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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MEF2B

Z-value: 0.43

Motif logo

Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
ENSG00000213999.11 myocyte enhancer factor 2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Bhg19_v2_chr19_-_19281054_192810980.512.3e-02Click!

Activity profile of MEF2B motif

Sorted Z-values of MEF2B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_52445191 6.19 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
nuclear receptor subfamily 4, group A, member 1
chr12_+_52430894 1.90 ENST00000546842.1
nuclear receptor subfamily 4, group A, member 1
chr20_+_10199468 1.78 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr4_+_41362796 1.59 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr11_+_71934962 1.29 ENST00000543234.1
inositol polyphosphate phosphatase-like 1
chr22_-_51017084 1.10 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chr9_+_97766409 1.02 ENST00000425634.2
chromosome 9 open reading frame 3
chr22_-_51016846 1.01 ENST00000312108.7
ENST00000395650.2
carnitine palmitoyltransferase 1B (muscle)
chr6_-_33160231 0.94 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
collagen, type XI, alpha 2
chr1_+_156095951 0.92 ENST00000448611.2
ENST00000368297.1
lamin A/C
chr1_-_204329013 0.91 ENST00000272203.3
ENST00000414478.1
pleckstrin homology domain containing, family A member 6
chr5_+_155753745 0.89 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr17_-_42200996 0.88 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr2_-_165424973 0.86 ENST00000543549.1
growth factor receptor-bound protein 14
chr2_-_157198860 0.86 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr9_-_74980113 0.84 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
zinc finger, AN1-type domain 5
chr2_-_86564776 0.83 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr16_-_88717482 0.82 ENST00000261623.3
cytochrome b-245, alpha polypeptide
chr1_+_156096336 0.80 ENST00000504687.1
ENST00000473598.2
lamin A/C
chr3_+_8543561 0.79 ENST00000397386.3
LIM and cysteine-rich domains 1
chr20_+_10199566 0.78 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chr7_-_16872932 0.77 ENST00000419572.2
ENST00000412973.1
anterior gradient 2
chr12_+_52431016 0.71 ENST00000553200.1
nuclear receptor subfamily 4, group A, member 1
chr17_-_42200958 0.70 ENST00000336057.5
histone deacetylase 5
chr12_-_49393092 0.70 ENST00000421952.2
dendrin
chr3_+_8543393 0.70 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr3_-_52486841 0.65 ENST00000496590.1
troponin C type 1 (slow)
chr12_+_54384370 0.62 ENST00000504315.1
homeobox C6
chr4_+_41362615 0.60 ENST00000509638.1
LIM and calponin homology domains 1
chr3_+_8543533 0.59 ENST00000454244.1
LIM and cysteine-rich domains 1
chr22_-_30642782 0.56 ENST00000249075.3
leukemia inhibitory factor
chr9_+_100263912 0.56 ENST00000259365.4
tropomodulin 1
chr3_+_49057876 0.56 ENST00000326912.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr17_-_48785216 0.55 ENST00000285243.6
ankyrin repeat domain 40
chr8_+_76452097 0.53 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr16_-_88717423 0.49 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
cytochrome b-245, alpha polypeptide
chr2_+_33661382 0.48 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_233497931 0.48 ENST00000264059.3
EF-hand domain family, member D1
chr1_+_212782012 0.47 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr17_-_42188598 0.45 ENST00000591714.1
histone deacetylase 5
chr2_-_190044480 0.45 ENST00000374866.3
collagen, type V, alpha 2
chr22_-_30642728 0.45 ENST00000403987.3
leukemia inhibitory factor
chr7_-_37488834 0.45 ENST00000310758.4
engulfment and cell motility 1
chr11_+_7597639 0.43 ENST00000533792.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_86564740 0.43 ENST00000540790.1
ENST00000428491.1
receptor accessory protein 1
chr3_+_179370517 0.42 ENST00000263966.3
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr5_-_16509101 0.42 ENST00000399793.2
family with sequence similarity 134, member B
chr19_-_40324767 0.42 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chrX_+_70521584 0.40 ENST00000373829.3
ENST00000538820.1
integrin beta 1 binding protein (melusin) 2
chr19_-_40324255 0.39 ENST00000593685.1
ENST00000600611.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr3_-_137834436 0.39 ENST00000327532.2
ENST00000467030.1
DAZ interacting zinc finger protein 1-like
chr17_-_5322786 0.39 ENST00000225696.4
nucleoporin 88kDa
chr11_-_18034701 0.38 ENST00000265965.5
secretion regulating guanine nucleotide exchange factor
chr17_-_34417479 0.37 ENST00000225245.5
chemokine (C-C motif) ligand 3
chr6_+_44194762 0.36 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr7_-_121944491 0.33 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr1_-_150693318 0.32 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMA domain containing 1
chr2_-_86564696 0.32 ENST00000437769.1
receptor accessory protein 1
chr3_-_192445289 0.32 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
fibroblast growth factor 12
chr7_-_37488777 0.32 ENST00000445322.1
ENST00000448602.1
engulfment and cell motility 1
chr12_-_120189900 0.31 ENST00000546026.1
citron (rho-interacting, serine/threonine kinase 21)
chr8_-_62602327 0.31 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
aspartate beta-hydroxylase
chr17_-_1389228 0.30 ENST00000438665.2
myosin IC
chr19_-_16008880 0.30 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr11_+_47293795 0.29 ENST00000422579.1
MAP-kinase activating death domain
chr18_+_12407895 0.29 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
slowmo homolog 1 (Drosophila)
chr4_+_120056939 0.27 ENST00000307128.5
myozenin 2
chr20_+_11898507 0.27 ENST00000378226.2
BTB (POZ) domain containing 3
chr17_+_42248063 0.27 ENST00000293414.1
ankyrin repeat and SOCS box containing 16
chr9_-_85882145 0.26 ENST00000328788.1
FERM domain containing 3
chr9_-_16728161 0.24 ENST00000603713.1
ENST00000603313.1
basonuclin 2
chr11_-_47374246 0.23 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
myosin binding protein C, cardiac
chr1_+_145524891 0.20 ENST00000369304.3
integrin, alpha 10
chr5_-_11903337 0.20 ENST00000502551.1
catenin (cadherin-associated protein), delta 2
chr1_+_145525015 0.19 ENST00000539363.1
ENST00000538811.1
integrin, alpha 10
chr8_-_27115903 0.19 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr1_-_150693305 0.19 ENST00000368987.1
HORMA domain containing 1
chr20_+_32581525 0.18 ENST00000246194.3
ENST00000413297.1
RALY heterogeneous nuclear ribonucleoprotein
chr5_-_111091948 0.18 ENST00000447165.2
neuronal regeneration related protein
chr17_+_20059302 0.18 ENST00000395530.2
sperm antigen with calponin homology and coiled-coil domains 1
chr20_-_62582475 0.17 ENST00000369908.5
uridine-cytidine kinase 1-like 1
chr14_+_76776957 0.17 ENST00000512784.1
estrogen-related receptor beta
chr17_-_1389419 0.16 ENST00000575158.1
myosin IC
chr16_+_50313426 0.16 ENST00000569265.1
adenylate cyclase 7
chr2_+_170366203 0.16 ENST00000284669.1
kelch-like family member 41
chrX_-_15332665 0.16 ENST00000537676.1
ENST00000344384.4
ankyrin repeat and SOCS box containing 11
chr4_+_8321882 0.16 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
chr11_+_7598239 0.15 ENST00000525597.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_-_72268889 0.14 ENST00000388742.4
eyes absent homolog 1 (Drosophila)
chr16_+_12059091 0.14 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr5_-_11903475 0.14 ENST00000508761.1
catenin (cadherin-associated protein), delta 2
chr8_-_27115931 0.13 ENST00000523048.1
stathmin-like 4
chr14_+_101359265 0.13 ENST00000599197.1
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr2_-_218766698 0.13 ENST00000439083.1
tensin 1
chr5_+_132009675 0.13 ENST00000231449.2
ENST00000350025.2
interleukin 4
chr6_+_123038689 0.12 ENST00000354275.2
ENST00000368446.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr6_-_123957942 0.11 ENST00000398178.3
triadin
chr8_-_72268968 0.11 ENST00000388740.3
eyes absent homolog 1 (Drosophila)
chr18_-_35145981 0.11 ENST00000420428.2
ENST00000412753.1
CUGBP, Elav-like family member 4
chr7_-_37488547 0.11 ENST00000453399.1
engulfment and cell motility 1
chr6_-_123958051 0.10 ENST00000546248.1
triadin
chr1_+_74701062 0.10 ENST00000326637.3
TNNI3 interacting kinase
chr10_-_97200772 0.10 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
sorbin and SH3 domain containing 1
chr18_-_3220106 0.10 ENST00000356443.4
ENST00000400569.3
myomesin 1
chr3_-_39234074 0.09 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
xin actin-binding repeat containing 1
chr3_+_54157480 0.09 ENST00000490478.1
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr18_-_3219847 0.08 ENST00000261606.7
myomesin 1
chr11_-_47400062 0.08 ENST00000533030.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr5_-_66492562 0.08 ENST00000256447.4
CD180 molecule
chr11_-_104480019 0.08 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chrX_-_138304939 0.08 ENST00000448673.1
fibroblast growth factor 13
chr17_-_27467418 0.08 ENST00000528564.1
myosin XVIIIA
chr10_+_71561630 0.08 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
collagen, type XIII, alpha 1
chr4_-_185303418 0.07 ENST00000610223.1
ENST00000608785.1
RP11-290F5.1
chr7_+_86781916 0.07 ENST00000579592.1
ENST00000434534.1
cyclin D binding myb-like transcription factor 1
chr7_+_75931861 0.07 ENST00000248553.6
heat shock 27kDa protein 1
chr3_+_46924829 0.07 ENST00000313049.5
parathyroid hormone 1 receptor
chr10_-_75415825 0.07 ENST00000394810.2
synaptopodin 2-like
chr1_+_84630645 0.07 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_99548270 0.06 ENST00000546568.1
ENST00000332712.7
ENST00000546960.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_-_70546897 0.06 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
solute carrier family 8 (sodium/calcium exchanger), member 3
chrX_-_142722897 0.06 ENST00000338017.4
SLIT and NTRK-like family, member 4
chr10_+_71561704 0.06 ENST00000520267.1
collagen, type XIII, alpha 1
chr12_+_15699286 0.05 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
protein tyrosine phosphatase, receptor type, O
chr11_-_47400032 0.05 ENST00000533968.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr7_-_15726296 0.05 ENST00000262041.5
mesenchyme homeobox 2
chr14_-_102704783 0.05 ENST00000522534.1
MOK protein kinase
chr9_+_116327326 0.05 ENST00000342620.5
regulator of G-protein signaling 3
chr2_+_33683109 0.05 ENST00000437184.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr10_-_69455873 0.05 ENST00000433211.2
catenin (cadherin-associated protein), alpha 3
chr11_-_84634447 0.05 ENST00000532653.1
discs, large homolog 2 (Drosophila)
chr11_-_47400078 0.04 ENST00000378538.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr18_+_3252206 0.04 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr3_-_11610255 0.04 ENST00000424529.2
vestigial like 4 (Drosophila)
chr13_+_39261224 0.04 ENST00000280481.7
FRAS1 related extracellular matrix protein 2
chr2_-_145188137 0.04 ENST00000440875.1
zinc finger E-box binding homeobox 2
chr1_+_84630367 0.04 ENST00000370680.1
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_30951461 0.03 ENST00000311813.4
aquaporin 1 (Colton blood group)
chr12_-_5352315 0.03 ENST00000536518.1
RP11-319E16.1
chr16_-_56223480 0.03 ENST00000565155.1
RP11-461O7.1
chr9_-_102582155 0.03 ENST00000427039.1
RP11-554F20.1
chr11_-_84634217 0.03 ENST00000524982.1
discs, large homolog 2 (Drosophila)
chr2_+_168043793 0.03 ENST00000409273.1
ENST00000409605.1
xin actin-binding repeat containing 2
chr10_+_71561649 0.03 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
collagen, type XIII, alpha 1
chr14_-_22005343 0.03 ENST00000327430.3
spalt-like transcription factor 2
chr20_+_44657845 0.02 ENST00000243964.3
solute carrier family 12 (potassium/chloride transporter), member 5
chr11_-_47399942 0.02 ENST00000227163.4
spleen focus forming virus (SFFV) proviral integration oncogene
chr12_-_371994 0.02 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
solute carrier family 6 (neurotransmitter transporter), member 13
chr4_+_37892682 0.02 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr11_+_75110530 0.02 ENST00000531188.1
ENST00000530164.1
ENST00000422465.2
ENST00000278572.6
ENST00000534440.1
ENST00000527446.1
ENST00000526608.1
ENST00000527273.1
ENST00000524851.1
ribosomal protein S3
chr16_+_31225337 0.02 ENST00000322122.3
tripartite motif containing 72
chr7_+_86781847 0.01 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
cyclin D binding myb-like transcription factor 1
chr20_+_61147651 0.01 ENST00000370527.3
ENST00000370524.2
chromosome 20 open reading frame 166
chrX_-_63450480 0.01 ENST00000362002.2
ankyrin repeat and SOCS box containing 12
chrX_-_11284095 0.01 ENST00000303025.6
ENST00000534860.1
Rho GTPase activating protein 6
chr8_+_11351876 0.01 ENST00000529894.1
B lymphoid tyrosine kinase
chr10_-_31146615 0.01 ENST00000444692.2
zinc finger protein 438
chr6_+_139094657 0.00 ENST00000332797.6
coiled-coil domain containing 28A

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.7 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.6 2.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.3 1.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.3 1.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 1.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.9 GO:0060023 soft palate development(GO:0060023)
0.2 0.5 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.2 0.6 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.8 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 2.1 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 2.1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 1.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.2 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.1 2.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 1.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.8 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.9 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 1.7 GO:0005638 lamin filament(GO:0005638)
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 8.0 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.3 1.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 2.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 2.0 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 10.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.9 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.8 GO:0031013 troponin I binding(GO:0031013)
0.1 1.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 2.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 2.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 2.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4