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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MEF2C

Z-value: 0.43

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Transcription factors associated with MEF2C

Gene Symbol Gene ID Gene Info
MEF2C
ENSG00000081189.9 myocyte enhancer factor 2C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Chg19_v2_chr5_-_88178964_881790120.801.9e-05Click!

Activity profile of MEF2C motif

Sorted Z-values of MEF2C motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_143226979 1.85 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_143227088 1.79 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_-_49834299 1.78 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr8_-_49833978 1.70 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr1_-_209975494 1.46 ENST00000456314.1
IRF6
interferon regulatory factor 6
chr3_+_99357319 1.42 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1
collagen, type VIII, alpha 1
chr18_+_29027696 1.35 ENST00000257189.4
DSG3
desmoglein 3
chr1_+_68150744 1.22 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr3_-_176914191 1.22 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr15_+_78558523 1.14 ENST00000446172.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr7_+_18535321 1.08 ENST00000413380.1
ENST00000430454.1
HDAC9
histone deacetylase 9
chr3_+_135741576 1.07 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr14_-_23652849 1.01 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr10_-_3827371 1.01 ENST00000469435.1
KLF6
Kruppel-like factor 6
chr7_+_18535346 1.00 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr4_-_143767428 0.98 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr17_+_80186908 0.97 ENST00000582743.1
ENST00000578684.1
ENST00000577650.1
ENST00000582715.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr14_-_61748550 0.94 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr2_-_151344172 0.91 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr6_+_15401075 0.87 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr2_-_208031542 0.82 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr10_-_3827417 0.77 ENST00000497571.1
ENST00000542957.1
KLF6
Kruppel-like factor 6
chr8_-_139926236 0.76 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr4_+_89514402 0.76 ENST00000426683.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr1_+_230193521 0.74 ENST00000543760.1
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr21_+_39628852 0.72 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_208030886 0.70 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr4_+_160203650 0.68 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr7_+_18126557 0.67 ENST00000417496.2
HDAC9
histone deacetylase 9
chr4_+_89514516 0.65 ENST00000452979.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr7_+_18535893 0.64 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chrX_+_131157609 0.63 ENST00000496850.1
MST4
Serine/threonine-protein kinase MST4
chr2_+_148778570 0.62 ENST00000407073.1
MBD5
methyl-CpG binding domain protein 5
chr15_+_42651691 0.62 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
CAPN3
calpain 3, (p94)
chr5_-_137475071 0.62 ENST00000265191.2
NME5
NME/NM23 family member 5
chr18_+_9708162 0.61 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr20_+_22034809 0.61 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr3_-_48598547 0.60 ENST00000536104.1
ENST00000452531.1
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr3_+_138067521 0.58 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr21_+_39628655 0.58 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr20_+_58251716 0.57 ENST00000355648.4
PHACTR3
phosphatase and actin regulator 3
chr7_+_18536090 0.57 ENST00000441986.1
HDAC9
histone deacetylase 9
chr22_+_32340447 0.57 ENST00000248975.5
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr1_-_230513367 0.56 ENST00000321327.2
ENST00000525115.1
PGBD5
piggyBac transposable element derived 5
chr8_+_104831472 0.56 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr22_+_32340481 0.56 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr3_-_176914238 0.56 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr9_+_127054254 0.55 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr15_+_68582544 0.54 ENST00000566008.1
FEM1B
fem-1 homolog b (C. elegans)
chr13_+_76378357 0.52 ENST00000489941.2
ENST00000525373.1
LMO7
LIM domain 7
chr4_+_169418255 0.52 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr3_+_138067314 0.52 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chr2_+_220144168 0.50 ENST00000392087.2
ENST00000442681.1
ENST00000439026.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr12_+_14561422 0.49 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr3_+_138067666 0.48 ENST00000475711.1
ENST00000464896.1
MRAS
muscle RAS oncogene homolog
chr22_+_41487711 0.48 ENST00000263253.7
EP300
E1A binding protein p300
chr3_-_112360116 0.48 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr1_+_201617450 0.46 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1
neuron navigator 1
chr3_+_141106458 0.46 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr13_+_76334498 0.46 ENST00000534657.1
LMO7
LIM domain 7
chr15_+_40531243 0.45 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_+_182850743 0.45 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr8_+_107282389 0.45 ENST00000577661.1
ENST00000445937.1
RP11-395G23.3
OXR1
RP11-395G23.3
oxidation resistance 1
chr3_-_149510553 0.45 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr16_+_14280742 0.45 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr3_-_38071122 0.45 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr2_+_220299547 0.44 ENST00000312358.7
SPEG
SPEG complex locus
chr2_-_208030647 0.43 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_-_201346761 0.42 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr11_-_85780853 0.42 ENST00000531930.1
ENST00000528398.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr19_+_37096194 0.41 ENST00000460670.1
ENST00000292928.2
ENST00000439428.1
ZNF382
zinc finger protein 382
chr1_-_201390846 0.41 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1
troponin I type 1 (skeletal, slow)
chr15_+_40531621 0.41 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_+_220144052 0.41 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr1_-_31845914 0.41 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr13_+_76378407 0.41 ENST00000447038.1
LMO7
LIM domain 7
chr5_-_142065223 0.40 ENST00000378046.1
FGF1
fibroblast growth factor 1 (acidic)
chr4_+_160025300 0.40 ENST00000505478.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr13_-_30881134 0.39 ENST00000380617.3
ENST00000441394.1
KATNAL1
katanin p60 subunit A-like 1
chr17_+_7461580 0.39 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr1_+_16010779 0.39 ENST00000375799.3
ENST00000375793.2
PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr13_+_76378305 0.39 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr5_+_96077888 0.38 ENST00000509259.1
ENST00000503828.1
CAST
calpastatin
chr4_-_186697044 0.38 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr5_-_115910630 0.38 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr8_+_107282368 0.38 ENST00000521369.2
RP11-395G23.3
RP11-395G23.3
chr1_-_226187013 0.37 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr11_+_69924639 0.37 ENST00000538023.1
ENST00000398543.2
ANO1
anoctamin 1, calcium activated chloride channel
chr11_+_1860200 0.37 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr4_-_25865159 0.37 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr7_+_90032821 0.36 ENST00000427904.1
CLDN12
claudin 12
chr1_+_201617264 0.36 ENST00000367296.4
NAV1
neuron navigator 1
chr3_-_168864315 0.36 ENST00000475754.1
ENST00000484519.1
MECOM
MDS1 and EVI1 complex locus
chr8_-_73793975 0.36 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr10_-_29923893 0.36 ENST00000355867.4
SVIL
supervillin
chr1_+_90098606 0.35 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr12_+_53846594 0.35 ENST00000550192.1
PCBP2
poly(rC) binding protein 2
chrX_-_50386648 0.35 ENST00000460112.3
SHROOM4
shroom family member 4
chr3_+_186739636 0.35 ENST00000440338.1
ENST00000448044.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr10_-_62060232 0.35 ENST00000503925.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_21493123 0.34 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr9_-_110251836 0.33 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr5_+_191592 0.33 ENST00000328278.3
LRRC14B
leucine rich repeat containing 14B
chr22_+_19706958 0.33 ENST00000395109.2
SEPT5
septin 5
chr4_-_57547870 0.32 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr8_-_72268721 0.32 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr16_-_18923035 0.32 ENST00000563836.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr10_-_61495760 0.32 ENST00000395347.1
SLC16A9
solute carrier family 16, member 9
chr2_+_220143989 0.32 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr5_+_138609782 0.31 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
MATR3
matrin 3
chr17_+_17685422 0.30 ENST00000395774.1
RAI1
retinoic acid induced 1
chrX_-_15683147 0.29 ENST00000380342.3
TMEM27
transmembrane protein 27
chr10_+_124134201 0.29 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr8_-_95565673 0.29 ENST00000437199.1
ENST00000297591.5
ENST00000421249.2
KIAA1429
KIAA1429
chr11_+_128563652 0.29 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chrX_-_109683446 0.29 ENST00000372057.1
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr13_-_30880979 0.29 ENST00000414289.1
KATNAL1
katanin p60 subunit A-like 1
chr5_-_142065612 0.29 ENST00000360966.5
ENST00000411960.1
FGF1
fibroblast growth factor 1 (acidic)
chr21_+_39628780 0.28 ENST00000417042.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_+_58797974 0.28 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr11_+_65266507 0.28 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chrX_+_135279179 0.28 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr12_+_53846612 0.28 ENST00000551104.1
PCBP2
poly(rC) binding protein 2
chr8_+_132952112 0.27 ENST00000520362.1
ENST00000519656.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr16_+_14280564 0.27 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr2_+_136343943 0.26 ENST00000409606.1
R3HDM1
R3H domain containing 1
chr1_+_160051319 0.26 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr14_+_56046914 0.26 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr1_+_24018269 0.26 ENST00000374550.3
RPL11
ribosomal protein L11
chr18_+_55862873 0.25 ENST00000588494.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr10_+_102758105 0.25 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr5_+_53751445 0.25 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr14_-_74462922 0.25 ENST00000553284.1
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr9_+_127054217 0.24 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr8_-_70745575 0.24 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr13_+_97928395 0.24 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr10_-_14880002 0.23 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr4_-_186696561 0.23 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr19_+_6739662 0.23 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10
thyroid hormone receptor interactor 10
chr7_-_143956815 0.23 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr11_-_19223523 0.23 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr5_+_173316341 0.23 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_59249732 0.23 ENST00000371222.2
JUN
jun proto-oncogene
chr11_+_19799327 0.23 ENST00000540292.1
NAV2
neuron navigator 2
chr4_+_100495864 0.22 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr10_-_61900762 0.22 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_+_159570722 0.22 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr2_-_220117867 0.21 ENST00000456818.1
ENST00000447205.1
TUBA4A
tubulin, alpha 4a
chr9_+_127023704 0.21 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr7_-_151217166 0.21 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr14_-_94421923 0.21 ENST00000555507.1
ASB2
ankyrin repeat and SOCS box containing 2
chr3_+_154797877 0.21 ENST00000462745.1
ENST00000493237.1
MME
membrane metallo-endopeptidase
chr1_-_156460391 0.21 ENST00000360595.3
MEF2D
myocyte enhancer factor 2D
chr11_+_1860682 0.21 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr17_+_7758374 0.21 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr14_+_56046990 0.20 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
KTN1
kinectin 1 (kinesin receptor)
chrX_-_131353461 0.20 ENST00000370874.1
RAP2C
RAP2C, member of RAS oncogene family
chr2_+_179184955 0.20 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr8_+_104831554 0.20 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_63661053 0.20 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr13_+_111766897 0.19 ENST00000317133.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr1_-_116383322 0.19 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr1_+_114473350 0.19 ENST00000503968.1
HIPK1
homeodomain interacting protein kinase 1
chr11_+_69924679 0.19 ENST00000531604.1
ANO1
anoctamin 1, calcium activated chloride channel
chr7_-_124569864 0.19 ENST00000609702.1
POT1
protection of telomeres 1
chr9_-_21995249 0.19 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr18_+_32402321 0.19 ENST00000587723.1
DTNA
dystrobrevin, alpha
chr7_-_124569991 0.19 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1
protection of telomeres 1
chr22_-_31328881 0.18 ENST00000445980.1
MORC2
MORC family CW-type zinc finger 2
chr1_-_154164534 0.18 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr1_+_92632542 0.18 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr18_+_42260059 0.18 ENST00000426838.4
SETBP1
SET binding protein 1
chr7_-_105332084 0.18 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr13_+_76334795 0.17 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr8_-_71157595 0.17 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr1_+_183605222 0.17 ENST00000536277.1
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_-_152131703 0.17 ENST00000316073.3
RPTN
repetin
chr1_+_104104379 0.17 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr11_+_1940925 0.16 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3
troponin T type 3 (skeletal, fast)
chr4_-_170192000 0.16 ENST00000502315.1
SH3RF1
SH3 domain containing ring finger 1
chr3_+_4535025 0.16 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr11_+_1860832 0.16 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr1_+_41447609 0.16 ENST00000543104.1
CTPS1
CTP synthase 1
chr8_+_104831440 0.16 ENST00000515551.1
RIMS2
regulating synaptic membrane exocytosis 2
chr1_-_204436344 0.16 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr4_-_186696425 0.16 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_214017151 0.16 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr7_-_55583740 0.15 ENST00000453256.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr5_-_131347501 0.15 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr8_+_22225041 0.15 ENST00000289952.5
ENST00000524285.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr4_-_57547454 0.15 ENST00000556376.2
HOPX
HOP homeobox
chr15_+_100106126 0.15 ENST00000558812.1
ENST00000338042.6
MEF2A
myocyte enhancer factor 2A
chr3_+_113616317 0.14 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr7_-_22259845 0.14 ENST00000420196.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr11_+_12108410 0.14 ENST00000527997.1
RP13-631K18.5
RP13-631K18.5
chr1_-_40042416 0.14 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr12_-_131200810 0.13 ENST00000536002.1
ENST00000544034.1
RIMBP2
RP11-662M24.2
RIMS binding protein 2
RP11-662M24.2
chr19_-_51220176 0.13 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr15_+_100106155 0.13 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
MEF2A
myocyte enhancer factor 2A
chr7_+_80267973 0.13 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 4.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 1.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 1.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.4 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 1.8 GO:0060613 fat pad development(GO:0060613)
0.1 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.6 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.6 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.4 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.9 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 1.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.3 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 5.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.4 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 1.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.6 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 2.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 1.0 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.2 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 1.5 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0098754 detoxification(GO:0098754) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0040040 thermosensory behavior(GO:0040040)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.2 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0061767 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0016528 sarcoplasm(GO:0016528)
0.1 1.4 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.3 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.3 GO:0005861 troponin complex(GO:0005861)
0.0 1.4 GO:0043194 axon initial segment(GO:0043194)
0.0 4.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.4 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 2.5 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.4 GO:0070538 oleic acid binding(GO:0070538)
0.1 1.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.7 GO:0030172 troponin C binding(GO:0030172)
0.1 1.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 2.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 1.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 1.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 1.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.6 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 3.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.2 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 2.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 7.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling