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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MEF2D_MEF2A

Z-value: 1.56

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Transcription factors associated with MEF2D_MEF2A

Gene Symbol Gene ID Gene Info
ENSG00000116604.13 myocyte enhancer factor 2D
ENSG00000068305.13 myocyte enhancer factor 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Dhg19_v2_chr1_-_156470515_156470542-0.651.9e-03Click!
MEF2Ahg19_v2_chr15_+_100106244_1001062920.213.7e-01Click!

Activity profile of MEF2D_MEF2A motif

Sorted Z-values of MEF2D_MEF2A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_52445191 27.88 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
nuclear receptor subfamily 4, group A, member 1
chr8_+_40010989 12.92 ENST00000315792.3
chromosome 8 open reading frame 4
chr7_-_134143841 8.96 ENST00000285930.4
aldo-keto reductase family 1, member B1 (aldose reductase)
chr12_+_52430894 8.66 ENST00000546842.1
nuclear receptor subfamily 4, group A, member 1
chr4_+_41362796 6.93 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr9_-_119162885 6.17 ENST00000445861.2
PAPPA antisense RNA 1
chr9_-_75567962 5.83 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr14_-_65409502 5.54 ENST00000389614.5
glutathione peroxidase 2 (gastrointestinal)
chr1_-_153518270 5.47 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chr5_+_155753745 4.98 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr22_-_51017084 4.94 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chr6_+_136172820 4.86 ENST00000308191.6
phosphodiesterase 7B
chrX_-_30327495 4.80 ENST00000453287.1
nuclear receptor subfamily 0, group B, member 1
chr2_-_165424973 4.72 ENST00000543549.1
growth factor receptor-bound protein 14
chr22_-_51016846 4.55 ENST00000312108.7
ENST00000395650.2
carnitine palmitoyltransferase 1B (muscle)
chr9_-_104145795 4.42 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr22_-_36013368 4.38 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr9_+_97766409 4.29 ENST00000425634.2
chromosome 9 open reading frame 3
chr17_-_42200996 4.08 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr17_+_37821593 3.85 ENST00000578283.1
titin-cap
chr14_+_103589789 3.83 ENST00000558056.1
ENST00000560869.1
tumor necrosis factor, alpha-induced protein 2
chr12_+_54384370 3.82 ENST00000504315.1
homeobox C6
chr17_+_6918064 3.77 ENST00000546760.1
ENST00000552402.1
chromosome 17 open reading frame 49
chr15_+_59730348 3.73 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr3_-_148939835 3.73 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr1_+_221051699 3.51 ENST00000366903.6
H2.0-like homeobox
chr14_-_65409438 3.49 ENST00000557049.1
glutathione peroxidase 2 (gastrointestinal)
chr12_+_52431016 3.46 ENST00000553200.1
nuclear receptor subfamily 4, group A, member 1
chr17_+_4855053 3.41 ENST00000518175.1
enolase 3 (beta, muscle)
chr9_-_74980113 3.35 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
zinc finger, AN1-type domain 5
chr13_-_67802549 3.34 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr12_+_40618764 3.29 ENST00000343742.2
leucine-rich repeat kinase 2
chr17_-_79900255 3.23 ENST00000330655.3
ENST00000582198.1
myeloid-associated differentiation marker-like 2
pyrroline-5-carboxylate reductase 1
chr17_-_42200958 3.22 ENST00000336057.5
histone deacetylase 5
chr7_-_121944491 3.13 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr11_+_57308979 3.07 ENST00000457912.1
smoothelin-like 1
chr17_+_6918093 3.05 ENST00000439424.2
chromosome 17 open reading frame 49
chr8_-_17533838 2.94 ENST00000400046.1
microtubule associated tumor suppressor 1
chr1_+_156095951 2.93 ENST00000448611.2
ENST00000368297.1
lamin A/C
chr17_-_48785216 2.90 ENST00000285243.6
ankyrin repeat domain 40
chr10_+_104178946 2.78 ENST00000432590.1
F-box and leucine-rich repeat protein 15
chr4_+_41362615 2.75 ENST00000509638.1
LIM and calponin homology domains 1
chr22_-_36018569 2.73 ENST00000419229.1
ENST00000406324.1
myoglobin
chr4_+_129730779 2.71 ENST00000226319.6
jade family PHD finger 1
chr8_-_27850180 2.68 ENST00000380385.2
ENST00000301906.4
ENST00000354914.3
scavenger receptor class A, member 5 (putative)
chr20_+_48807351 2.67 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chr17_-_34417479 2.66 ENST00000225245.5
chemokine (C-C motif) ligand 3
chr3_-_52486841 2.61 ENST00000496590.1
troponin C type 1 (slow)
chr3_-_148939598 2.61 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr12_+_20963632 2.57 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr7_-_11871815 2.56 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr7_+_95115210 2.50 ENST00000428113.1
ENST00000325885.5
ankyrin repeat and SOCS box containing 4
chr2_-_190044480 2.49 ENST00000374866.3
collagen, type V, alpha 2
chr6_-_76203454 2.48 ENST00000237172.7
filamin A interacting protein 1
chr1_+_114522049 2.43 ENST00000369551.1
ENST00000320334.4
olfactomedin-like 3
chr6_-_6007200 2.36 ENST00000244766.2
neuritin 1
chr9_+_100263912 2.35 ENST00000259365.4
tropomodulin 1
chr1_-_204329013 2.35 ENST00000272203.3
ENST00000414478.1
pleckstrin homology domain containing, family A member 6
chr6_+_132129151 2.31 ENST00000360971.2
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr6_-_76203345 2.28 ENST00000393004.2
filamin A interacting protein 1
chr12_-_49393092 2.26 ENST00000421952.2
dendrin
chr3_-_156878482 2.25 ENST00000295925.4
cyclin L1
chr3_-_137834436 2.24 ENST00000327532.2
ENST00000467030.1
DAZ interacting zinc finger protein 1-like
chr12_+_20963647 2.17 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr1_+_201979743 2.15 ENST00000446188.1
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr7_+_28448995 2.13 ENST00000424599.1
cAMP responsive element binding protein 5
chr9_+_129677039 2.12 ENST00000259351.5
ENST00000424082.2
ENST00000394022.3
ENST00000394011.3
ENST00000319107.4
Ral GEF with PH domain and SH3 binding motif 1
chr19_+_45973120 2.10 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr2_+_145780739 2.09 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
testis expressed 41 (non-protein coding)
chr8_+_27631903 2.08 ENST00000305188.8
establishment of sister chromatid cohesion N-acetyltransferase 2
chr4_+_95373037 2.06 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDZ and LIM domain 5
chr2_+_233497931 2.05 ENST00000264059.3
EF-hand domain family, member D1
chr1_+_156096336 2.04 ENST00000504687.1
ENST00000473598.2
lamin A/C
chr11_+_71934962 2.04 ENST00000543234.1
inositol polyphosphate phosphatase-like 1
chr10_+_28966271 2.03 ENST00000375533.3
BMP and activin membrane-bound inhibitor
chr2_+_33661382 2.01 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_+_54393880 2.01 ENST00000303450.4
homeobox C9
chr6_-_33160231 1.99 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
collagen, type XI, alpha 2
chr16_-_31021921 1.97 ENST00000215095.5
syntaxin 1B
chr4_+_129730839 1.96 ENST00000511647.1
jade family PHD finger 1
chr3_-_157823839 1.89 ENST00000425436.3
ENST00000389589.4
ENST00000441443.2
short stature homeobox 2
chr2_-_157198860 1.88 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr22_-_30642728 1.85 ENST00000403987.3
leukemia inhibitory factor
chr17_-_42188598 1.81 ENST00000591714.1
histone deacetylase 5
chr7_-_37488834 1.81 ENST00000310758.4
engulfment and cell motility 1
chr4_+_119809984 1.78 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
synaptopodin 2
chr3_+_8543561 1.78 ENST00000397386.3
LIM and cysteine-rich domains 1
chr15_-_70994612 1.76 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chrX_+_18725758 1.76 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr2_-_133429091 1.74 ENST00000345008.6
LY6/PLAUR domain containing 1
chr21_-_34185944 1.74 ENST00000479548.1
chromosome 21 open reading frame 62
chr10_-_72141330 1.72 ENST00000395011.1
ENST00000395010.1
leucine rich repeat containing 20
chr20_+_5987890 1.72 ENST00000378868.4
cardiolipin synthase 1
chr8_+_76452097 1.70 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chrX_-_55208866 1.66 ENST00000545075.1
MT-RNR2-like 10
chr3_+_8543393 1.64 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr8_-_62602327 1.63 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
aspartate beta-hydroxylase
chr3_+_36421826 1.62 ENST00000273183.3
SH3 and cysteine rich domain
chr17_+_68165657 1.61 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr15_-_83474806 1.59 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr22_-_31742218 1.53 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
POZ (BTB) and AT hook containing zinc finger 1
chr9_-_97356075 1.53 ENST00000375337.3
fructose-1,6-bisphosphatase 2
chr1_+_201979645 1.49 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr5_-_111091948 1.48 ENST00000447165.2
neuronal regeneration related protein
chr15_+_91446157 1.48 ENST00000559717.1
mannosidase, alpha, class 2A, member 2
chr17_-_79881408 1.47 ENST00000392366.3
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr21_-_34186006 1.44 ENST00000490358.1
chromosome 21 open reading frame 62
chr17_-_1389228 1.44 ENST00000438665.2
myosin IC
chr3_+_8543533 1.42 ENST00000454244.1
LIM and cysteine-rich domains 1
chr2_+_145780767 1.41 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
testis expressed 41 (non-protein coding)
chr9_-_33402506 1.41 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
aquaporin 7
chr18_+_12407895 1.39 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
slowmo homolog 1 (Drosophila)
chr1_+_95583479 1.36 ENST00000455656.1
ENST00000604534.1
transmembrane protein 56
TMEM56-RWDD3 readthrough
chr12_-_68845165 1.35 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2
chr7_-_37488777 1.35 ENST00000445322.1
ENST00000448602.1
engulfment and cell motility 1
chr17_-_6917755 1.34 ENST00000593646.1
Uncharacterized protein
chr3_-_131756559 1.34 ENST00000505957.1
copine IV
chr3_+_49057876 1.33 ENST00000326912.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr3_+_36421971 1.33 ENST00000457375.2
ENST00000434649.1
SH3 and cysteine rich domain
chr12_+_52203789 1.33 ENST00000599343.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr4_+_119810134 1.33 ENST00000434046.2
synaptopodin 2
chr3_-_156878540 1.32 ENST00000461804.1
cyclin L1
chr14_-_103589246 1.31 ENST00000558224.1
ENST00000560742.1
long intergenic non-protein coding RNA 677
chr16_+_30075595 1.29 ENST00000563060.2
aldolase A, fructose-bisphosphate
chr7_-_16872932 1.29 ENST00000419572.2
ENST00000412973.1
anterior gradient 2
chr20_+_42574317 1.29 ENST00000358131.5
TOX high mobility group box family member 2
chr6_-_3912207 1.27 ENST00000566733.1
RP1-140K8.5
chrX_+_70521584 1.27 ENST00000373829.3
ENST00000538820.1
integrin beta 1 binding protein (melusin) 2
chr11_+_7597639 1.27 ENST00000533792.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_-_16509101 1.26 ENST00000399793.2
family with sequence similarity 134, member B
chr7_-_35013217 1.26 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr11_+_45918092 1.26 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr16_+_30075783 1.22 ENST00000412304.2
aldolase A, fructose-bisphosphate
chr6_+_159291090 1.22 ENST00000367073.4
ENST00000608817.1
chromosome 6 open reading frame 99
chr3_+_179370517 1.21 ENST00000263966.3
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr14_-_23877474 1.21 ENST00000405093.3
myosin, heavy chain 6, cardiac muscle, alpha
chr17_-_38821373 1.20 ENST00000394052.3
keratin 222
chr17_+_42248063 1.17 ENST00000293414.1
ankyrin repeat and SOCS box containing 16
chr9_-_136344237 1.17 ENST00000432868.1
ENST00000371899.4
solute carrier family 2 (facilitated glucose transporter), member 6
chr12_-_14133053 1.16 ENST00000609686.1
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr3_-_157824292 1.16 ENST00000483851.2
short stature homeobox 2
chr4_-_39640513 1.14 ENST00000511809.1
ENST00000505729.1
small integral membrane protein 14
chr17_-_27467418 1.13 ENST00000528564.1
myosin XVIIIA
chr2_-_148778323 1.13 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr7_-_29152509 1.10 ENST00000448959.1
carboxypeptidase, vitellogenic-like
chr2_+_103378472 1.10 ENST00000412401.2
transmembrane protein 182
chr6_-_123957942 1.08 ENST00000398178.3
triadin
chr9_-_136344197 1.07 ENST00000414172.1
ENST00000371897.4
solute carrier family 2 (facilitated glucose transporter), member 6
chr9_-_15472730 1.07 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr15_+_74509530 1.07 ENST00000321288.5
coiled-coil domain containing 33
chr1_+_203097407 1.04 ENST00000367235.1
adenosine A1 receptor
chr11_-_47374246 1.04 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
myosin binding protein C, cardiac
chr2_-_148779106 1.04 ENST00000416719.1
ENST00000264169.2
origin recognition complex, subunit 4
chr16_+_30075463 1.04 ENST00000562168.1
ENST00000569545.1
aldolase A, fructose-bisphosphate
chrX_+_153046456 1.04 ENST00000393786.3
ENST00000370104.1
ENST00000370108.3
ENST00000370101.3
ENST00000430541.1
ENST00000370100.1
SRSF protein kinase 3
chr20_+_32581525 1.03 ENST00000246194.3
ENST00000413297.1
RALY heterogeneous nuclear ribonucleoprotein
chrX_-_21776281 1.01 ENST00000379494.3
small muscle protein, X-linked
chr10_+_95517566 1.01 ENST00000542308.1
leucine-rich, glioma inactivated 1
chr13_+_51483814 1.01 ENST00000336617.3
ENST00000422660.1
ribonuclease H2, subunit B
chr4_+_120056939 0.98 ENST00000307128.5
myozenin 2
chr6_-_123958051 0.98 ENST00000546248.1
triadin
chr1_-_205912577 0.98 ENST00000367135.3
ENST00000367134.2
solute carrier family 26 (anion exchanger), member 9
chr17_-_45899126 0.95 ENST00000007414.3
ENST00000392507.3
oxysterol binding protein-like 7
chr12_+_109554386 0.93 ENST00000338432.7
acetyl-CoA carboxylase beta
chr11_-_62457371 0.92 ENST00000317449.4
LRRN4 C-terminal like
chr22_-_40929812 0.92 ENST00000422851.1
megakaryoblastic leukemia (translocation) 1
chr6_+_44194762 0.92 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr3_-_121264848 0.92 ENST00000264233.5
polymerase (DNA directed), theta
chr14_+_24540154 0.90 ENST00000559778.1
ENST00000560761.1
ENST00000557889.1
copine VI (neuronal)
chr7_+_5465382 0.89 ENST00000609130.1
RP11-1275H24.2
chr16_-_3422283 0.89 ENST00000399974.3
MT-RNR2-like 4
chr2_-_148778258 0.88 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
origin recognition complex, subunit 4
chr4_-_23891658 0.87 ENST00000507380.1
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr17_-_72855989 0.87 ENST00000293190.5
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr10_+_95517616 0.86 ENST00000371418.4
leucine-rich, glioma inactivated 1
chr17_+_42264556 0.86 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
transmembrane and ubiquitin-like domain containing 2
chr10_-_62704005 0.86 ENST00000337910.5
Rho-related BTB domain containing 1
chr17_-_1389419 0.86 ENST00000575158.1
myosin IC
chr8_-_27850141 0.85 ENST00000524352.1
scavenger receptor class A, member 5 (putative)
chr12_+_21207503 0.85 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr9_-_16728161 0.85 ENST00000603713.1
ENST00000603313.1
basonuclin 2
chr2_+_85766280 0.85 ENST00000306434.3
methionine adenosyltransferase II, alpha
chr8_-_23282797 0.85 ENST00000524144.1
lysyl oxidase-like 2
chr12_-_12715266 0.83 ENST00000228862.2
dual specificity phosphatase 16
chr11_-_18034701 0.83 ENST00000265965.5
secretion regulating guanine nucleotide exchange factor
chr17_-_41132010 0.82 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1 readthrough
chr2_+_145780725 0.82 ENST00000451478.1
testis expressed 41 (non-protein coding)
chr3_-_39234074 0.82 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
xin actin-binding repeat containing 1
chr3_+_69812877 0.81 ENST00000457080.1
ENST00000328528.6
microphthalmia-associated transcription factor
chr4_-_23891693 0.81 ENST00000264867.2
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr8_-_23282820 0.81 ENST00000520871.1
lysyl oxidase-like 2
chr1_+_170115142 0.81 ENST00000439373.2
methyltransferase like 11B
chr3_-_192445289 0.80 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
fibroblast growth factor 12
chr7_-_150946015 0.80 ENST00000262188.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_223853425 0.80 ENST00000366873.2
ENST00000419193.2
calpain 8
chr9_-_85882145 0.79 ENST00000328788.1
FERM domain containing 3
chr7_-_151217001 0.78 ENST00000262187.5
Ras homolog enriched in brain
chr18_-_3220106 0.78 ENST00000356443.4
ENST00000400569.3
myomesin 1
chr4_+_124571409 0.78 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
long intergenic non-protein coding RNA 1091
chr17_+_42264322 0.77 ENST00000446571.3
ENST00000357984.3
ENST00000538716.2
transmembrane and ubiquitin-like domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 41.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
3.0 9.0 GO:0006059 hexitol metabolic process(GO:0006059)
1.3 12.9 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.1 3.3 GO:1903217 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
1.0 5.0 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
1.0 5.8 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.0 3.9 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.9 2.7 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.9 7.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.8 2.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.8 2.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.6 1.7 GO:1904640 positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.5 3.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 2.6 GO:0002086 diaphragm contraction(GO:0002086)
0.5 3.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.4 10.8 GO:0006853 carnitine shuttle(GO:0006853)
0.4 1.7 GO:0018277 protein deamination(GO:0018277)
0.4 1.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.4 2.0 GO:0060023 soft palate development(GO:0060023)
0.4 2.0 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.4 3.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.4 2.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4 1.5 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986)
0.4 2.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 1.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 4.4 GO:0019530 taurine metabolic process(GO:0019530)
0.3 1.0 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.3 2.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 9.3 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.3 1.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 0.9 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.3 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 2.4 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.3 5.9 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 0.9 GO:0033058 directional locomotion(GO:0033058)
0.3 1.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.3 3.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 3.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 3.0 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.3 0.5 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.2 1.4 GO:0036309 protein localization to M-band(GO:0036309)
0.2 3.6 GO:0060056 mammary gland involution(GO:0060056)
0.2 2.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.8 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2 2.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.8 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.2 0.8 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.2 0.8 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 3.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 1.7 GO:0015793 glycerol transport(GO:0015793)
0.2 3.8 GO:0051601 exocyst localization(GO:0051601)
0.2 1.7 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.2 6.3 GO:0006825 copper ion transport(GO:0006825)
0.2 0.9 GO:0015862 uridine transport(GO:0015862)
0.2 1.3 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.2 0.9 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 5.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 1.3 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.7 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 1.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.7 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.8 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 3.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 1.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 4.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 5.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.5 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 2.0 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 3.4 GO:0003016 respiratory system process(GO:0003016)
0.1 1.2 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1 0.7 GO:1903333 negative regulation of protein folding(GO:1903333)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 4.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.2 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 3.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.1 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.1 GO:0060789 hair follicle placode formation(GO:0060789)
0.1 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 1.1 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.1 2.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.2 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.7 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.4 GO:0046689 response to mercury ion(GO:0046689)
0.1 2.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 2.7 GO:0061615 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 3.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.4 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 7.8 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.1 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 3.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 4.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.8 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.9 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 2.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 7.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.8 GO:0043586 tongue development(GO:0043586)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 2.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.4 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.3 GO:0018212 peptidyl-tyrosine phosphorylation(GO:0018108) peptidyl-tyrosine modification(GO:0018212)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.5 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 2.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 4.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 1.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 1.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.6 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.7 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.5 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:0008542 visual learning(GO:0008542)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 1.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 1.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0007632 visual behavior(GO:0007632)
0.0 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.7 GO:0010761 fibroblast migration(GO:0010761)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.8 2.5 GO:0005588 collagen type V trimer(GO:0005588)
0.8 3.3 GO:0044753 amphisome(GO:0044753)
0.6 2.5 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.6 2.3 GO:0045160 myosin I complex(GO:0045160)
0.5 5.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 5.0 GO:0005638 lamin filament(GO:0005638)
0.4 3.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 4.8 GO:0042788 polysomal ribosome(GO:0042788)
0.3 1.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 2.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 0.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 2.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.3 GO:0005927 muscle tendon junction(GO:0005927)
0.2 2.5 GO:0030314 junctional membrane complex(GO:0030314)
0.2 5.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 0.8 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 3.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 0.9 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 2.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.2 GO:0032437 cuticular plate(GO:0032437)
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.3 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 7.6 GO:0031430 M band(GO:0031430)
0.1 2.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.8 GO:0032982 myosin filament(GO:0032982)
0.1 0.3 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 3.8 GO:0000145 exocyst(GO:0000145)
0.1 2.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 3.3 GO:0030315 T-tubule(GO:0030315)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.8 GO:0001739 sex chromatin(GO:0001739)
0.1 4.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.7 GO:0032039 integrator complex(GO:0032039)
0.1 30.7 GO:0031965 nuclear membrane(GO:0031965)
0.1 3.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.0 1.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 2.8 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 10.2 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 5.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 5.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0042383 sarcolemma(GO:0042383)
0.0 8.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 4.4 GO:0031674 I band(GO:0031674)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 10.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 2.1 GO:0043204 perikaryon(GO:0043204)
0.0 2.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.1 3.3 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
1.0 9.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.8 4.8 GO:0051373 FATZ binding(GO:0051373)
0.6 5.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6 9.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.6 1.8 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.6 1.7 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.5 1.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.5 3.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 2.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.5 6.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 2.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.4 1.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.4 49.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.4 7.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 12.9 GO:0005112 Notch binding(GO:0005112)
0.4 1.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.4 3.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.5 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.3 4.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 1.4 GO:0015254 glycerol channel activity(GO:0015254)
0.3 3.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 9.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 1.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.3 1.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 5.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.7 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 1.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 1.1 GO:0031432 titin binding(GO:0031432)
0.2 0.8 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 5.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 1.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 1.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 2.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 2.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 1.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 1.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 4.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 3.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.4 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 2.0 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 1.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 5.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.9 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 2.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.0 GO:0031013 troponin I binding(GO:0031013)
0.1 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.6 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 3.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.2 GO:0016594 glycine binding(GO:0016594)
0.1 1.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 3.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 1.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 4.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 2.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 4.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.1 GO:0043531 ADP binding(GO:0043531)
0.0 0.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 3.4 GO:0000149 SNARE binding(GO:0000149)
0.0 1.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 3.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 4.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 39.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 4.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 12.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 7.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.4 PID REELIN PATHWAY Reelin signaling pathway
0.1 6.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 4.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 5.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 5.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 5.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 37.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.5 9.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 5.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 10.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 1.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 3.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 6.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 5.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 3.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 7.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 4.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 6.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 9.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 3.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 5.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 6.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 4.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling