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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MEIS3_TGIF2LX

Z-value: 0.41

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Transcription factors associated with MEIS3_TGIF2LX

Gene Symbol Gene ID Gene Info
MEIS3
ENSG00000105419.13 Meis homeobox 3
TGIF2LX
ENSG00000153779.8 TGFB induced factor homeobox 2 like X-linked

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEIS3hg19_v2_chr19_-_47922373_479225720.741.7e-04Click!

Activity profile of MEIS3_TGIF2LX motif

Sorted Z-values of MEIS3_TGIF2LX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_153775426 1.85 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr15_+_65337708 1.18 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr2_-_42160486 1.12 ENST00000427054.1
AC104654.2
AC104654.2
chr1_-_47655686 0.93 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr16_+_69458428 0.87 ENST00000512062.1
ENST00000307892.8
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr16_+_69458537 0.80 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr1_+_8378140 0.80 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr1_-_153517473 0.79 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr10_-_5060201 0.74 ENST00000407674.1
AKR1C2
aldo-keto reductase family 1, member C2
chr16_+_30212378 0.74 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr11_-_615570 0.68 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chrX_-_153775760 0.67 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
G6PD
glucose-6-phosphate dehydrogenase
chr5_-_58882219 0.66 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_76139741 0.66 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
UPK3B
uroplakin 3B
chr2_+_97202480 0.63 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr10_-_5060147 0.62 ENST00000604507.1
AKR1C2
aldo-keto reductase family 1, member C2
chr19_+_1000418 0.62 ENST00000234389.3
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr3_-_49726486 0.59 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr12_+_121647868 0.57 ENST00000359949.7
ENST00000541532.1
ENST00000543171.1
ENST00000538701.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr8_+_56014949 0.57 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_+_10560147 0.55 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chr12_-_53298841 0.55 ENST00000293308.6
KRT8
keratin 8
chr2_+_97203082 0.54 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr11_+_71934962 0.53 ENST00000543234.1
INPPL1
inositol polyphosphate phosphatase-like 1
chr11_-_65325664 0.51 ENST00000301873.5
LTBP3
latent transforming growth factor beta binding protein 3
chr18_+_3449330 0.48 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr2_-_242089677 0.48 ENST00000405260.1
PASK
PAS domain containing serine/threonine kinase
chr7_+_76139833 0.48 ENST00000257632.5
UPK3B
uroplakin 3B
chr17_-_19648916 0.47 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr5_+_155753745 0.46 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr11_-_842509 0.44 ENST00000322028.4
POLR2L
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
chr11_+_67776012 0.44 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr22_+_35776354 0.44 ENST00000412893.1
HMOX1
heme oxygenase (decycling) 1
chr22_-_30953587 0.44 ENST00000453479.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr2_-_175202151 0.43 ENST00000595354.1
AC018470.1
Uncharacterized protein FLJ46347
chr6_+_160769399 0.43 ENST00000392145.1
SLC22A3
solute carrier family 22 (organic cation transporter), member 3
chr6_+_160769300 0.43 ENST00000275300.2
SLC22A3
solute carrier family 22 (organic cation transporter), member 3
chr19_+_18530146 0.42 ENST00000348495.6
ENST00000270061.7
SSBP4
single stranded DNA binding protein 4
chr19_-_4559814 0.41 ENST00000586582.1
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr7_-_156803329 0.41 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr20_+_306221 0.40 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr12_+_121647962 0.40 ENST00000542067.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr7_-_128415844 0.39 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr2_-_3595547 0.38 ENST00000438485.1
RP13-512J5.1
Uncharacterized protein
chr1_+_159750720 0.37 ENST00000368109.1
ENST00000368108.3
DUSP23
dual specificity phosphatase 23
chr9_-_86432547 0.37 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr20_+_306177 0.36 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr1_+_159750776 0.36 ENST00000368107.1
DUSP23
dual specificity phosphatase 23
chr3_-_52719888 0.35 ENST00000458294.1
PBRM1
polybromo 1
chr19_-_41256207 0.35 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr13_-_67802549 0.33 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr12_+_52203789 0.32 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr7_+_76139925 0.32 ENST00000394849.1
UPK3B
uroplakin 3B
chr19_+_18530184 0.31 ENST00000601357.2
SSBP4
single stranded DNA binding protein 4
chr3_-_122512619 0.31 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr14_-_54418598 0.30 ENST00000609748.1
ENST00000558961.1
BMP4
bone morphogenetic protein 4
chrX_+_118602363 0.30 ENST00000317881.8
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr11_-_76381029 0.29 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chrX_+_153775821 0.29 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr11_+_61447845 0.29 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr17_-_33446820 0.29 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr11_-_107590383 0.28 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chrX_+_153775869 0.28 ENST00000424839.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr17_+_73089382 0.28 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr17_-_6917755 0.26 ENST00000593646.1
AC040977.1
Uncharacterized protein
chr10_-_7661623 0.24 ENST00000298441.6
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr7_-_29234802 0.24 ENST00000449801.1
ENST00000409850.1
CPVL
carboxypeptidase, vitellogenic-like
chr17_+_39846114 0.24 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr15_-_74284613 0.24 ENST00000316911.6
ENST00000564777.1
ENST00000566081.1
ENST00000316900.5
STOML1
stomatin (EPB72)-like 1
chr9_+_96026230 0.22 ENST00000448251.1
WNK2
WNK lysine deficient protein kinase 2
chr17_-_33446735 0.22 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr18_+_3449821 0.21 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr15_-_74284558 0.21 ENST00000359750.4
ENST00000541638.1
ENST00000562453.1
STOML1
stomatin (EPB72)-like 1
chr18_+_68002675 0.21 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr3_-_3221358 0.21 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr18_+_3449695 0.20 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr2_+_220379052 0.20 ENST00000347842.3
ENST00000358078.4
ASIC4
acid-sensing (proton-gated) ion channel family member 4
chr11_+_827553 0.20 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr11_+_102188272 0.20 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr6_-_33160231 0.20 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr14_-_80677613 0.19 ENST00000556811.1
DIO2
deiodinase, iodothyronine, type II
chr19_-_50400212 0.19 ENST00000391826.2
IL4I1
interleukin 4 induced 1
chr9_+_137967268 0.19 ENST00000371799.4
ENST00000277415.11
OLFM1
olfactomedin 1
chr17_-_76220740 0.19 ENST00000600484.1
AC087645.1
Uncharacterized protein
chr12_+_120875910 0.19 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr3_+_8775466 0.19 ENST00000343849.2
ENST00000397368.2
CAV3
caveolin 3
chrX_+_17755696 0.18 ENST00000419185.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr19_-_4670345 0.18 ENST00000599630.1
ENST00000262947.3
C19orf10
chromosome 19 open reading frame 10
chr6_-_52860171 0.17 ENST00000370963.4
GSTA4
glutathione S-transferase alpha 4
chrX_+_17755563 0.17 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr19_-_10227503 0.17 ENST00000593054.1
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr11_+_102188224 0.16 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr11_+_64073699 0.16 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr2_-_55920952 0.16 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr4_+_671711 0.16 ENST00000400159.2
MYL5
myosin, light chain 5, regulatory
chr7_-_7782204 0.16 ENST00000418534.2
AC007161.5
AC007161.5
chr1_+_228395755 0.16 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr21_-_46954529 0.16 ENST00000485649.2
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr22_+_46731596 0.16 ENST00000381019.3
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr12_+_100867694 0.16 ENST00000392986.3
ENST00000549996.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr5_+_142286887 0.16 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr17_+_41003166 0.15 ENST00000308423.2
AOC3
amine oxidase, copper containing 3
chrX_-_23926004 0.15 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr15_-_78592053 0.15 ENST00000267973.2
WDR61
WD repeat domain 61
chr6_+_24495067 0.15 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr4_-_100871506 0.15 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr2_+_26785409 0.14 ENST00000329615.3
ENST00000409392.1
C2orf70
chromosome 2 open reading frame 70
chr9_-_140444814 0.14 ENST00000277531.4
PNPLA7
patatin-like phospholipase domain containing 7
chr8_+_126103921 0.14 ENST00000523741.1
NSMCE2
non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr7_-_150675372 0.14 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr16_-_10868853 0.14 ENST00000572428.1
TVP23A
trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
chr15_-_78591912 0.14 ENST00000560569.1
ENST00000558459.1
ENST00000558311.1
WDR61
WD repeat domain 61
chr17_+_6916957 0.14 ENST00000547302.2
RNASEK-C17orf49
RNASEK-C17orf49 readthrough
chr3_-_149093499 0.13 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr17_+_58755184 0.13 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr8_-_98290087 0.13 ENST00000322128.3
TSPYL5
TSPY-like 5
chr2_-_239149300 0.13 ENST00000436051.1
HES6
hes family bHLH transcription factor 6
chr6_-_33663474 0.13 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr19_-_40791302 0.13 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr8_+_26240414 0.13 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr17_-_41465674 0.13 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
LINC00910
long intergenic non-protein coding RNA 910
chr12_-_81763184 0.13 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chrX_+_41548220 0.13 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr19_-_5680231 0.13 ENST00000587950.1
C19orf70
chromosome 19 open reading frame 70
chr11_+_19138670 0.13 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr2_-_61697862 0.12 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr19_+_6361754 0.12 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr4_+_78783674 0.12 ENST00000315567.8
MRPL1
mitochondrial ribosomal protein L1
chr14_-_80677815 0.12 ENST00000557125.1
ENST00000555750.1
DIO2
deiodinase, iodothyronine, type II
chr10_+_114169299 0.12 ENST00000369410.3
ACSL5
acyl-CoA synthetase long-chain family member 5
chr2_-_158182105 0.12 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr15_-_78112553 0.12 ENST00000562933.1
LINGO1
leucine rich repeat and Ig domain containing 1
chrX_+_47420516 0.12 ENST00000377045.4
ENST00000290277.6
ENST00000377039.2
ARAF
v-raf murine sarcoma 3611 viral oncogene homolog
chr7_-_99332719 0.12 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr18_+_55018044 0.12 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr9_+_100174344 0.12 ENST00000422139.2
TDRD7
tudor domain containing 7
chr12_+_100867486 0.11 ENST00000548884.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr9_+_136501478 0.11 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr12_-_81763127 0.11 ENST00000541017.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr12_-_133787772 0.11 ENST00000545350.1
AC226150.4
Uncharacterized protein
chr18_-_52989525 0.11 ENST00000457482.3
TCF4
transcription factor 4
chr1_+_154975110 0.11 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chrX_+_135730373 0.11 ENST00000370628.2
CD40LG
CD40 ligand
chr17_+_34431212 0.10 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr10_+_51187938 0.10 ENST00000311663.5
FAM21D
family with sequence similarity 21, member D
chr16_-_18468926 0.10 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr16_+_20817839 0.10 ENST00000348433.6
ENST00000568501.1
ENST00000566276.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr1_-_16539094 0.10 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr9_-_37592561 0.10 ENST00000544379.1
ENST00000377773.5
ENST00000401811.3
ENST00000321301.6
TOMM5
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr11_+_7273181 0.10 ENST00000318881.6
SYT9
synaptotagmin IX
chr10_-_73848531 0.10 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chrX_+_135730297 0.10 ENST00000370629.2
CD40LG
CD40 ligand
chr4_-_184241927 0.10 ENST00000323319.5
CLDN22
claudin 22
chr2_+_149402553 0.10 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr19_+_50183032 0.10 ENST00000527412.1
PRMT1
protein arginine methyltransferase 1
chr17_+_37782955 0.10 ENST00000580825.1
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr9_-_130541017 0.10 ENST00000314830.8
SH2D3C
SH2 domain containing 3C
chr7_+_29234375 0.10 ENST00000409350.1
ENST00000495789.2
ENST00000539389.1
CHN2
chimerin 2
chr3_+_111260954 0.09 ENST00000283285.5
CD96
CD96 molecule
chr9_-_90589402 0.09 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20
cyclin-dependent kinase 20
chr3_+_111260856 0.09 ENST00000352690.4
CD96
CD96 molecule
chr6_+_112375275 0.09 ENST00000368666.2
ENST00000604763.1
ENST00000230529.5
WISP3
WNT1 inducible signaling pathway protein 3
chr10_-_73848764 0.09 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr19_+_17982747 0.09 ENST00000222248.3
SLC5A5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr1_+_79115503 0.09 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chrX_-_148713440 0.09 ENST00000536359.1
ENST00000316916.8
TMEM185A
transmembrane protein 185A
chrX_-_148713365 0.09 ENST00000511776.1
ENST00000507237.1
TMEM185A
transmembrane protein 185A
chrX_+_41548259 0.09 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr3_-_47023455 0.09 ENST00000446836.1
ENST00000425441.1
CCDC12
coiled-coil domain containing 12
chr20_+_35504522 0.09 ENST00000602922.1
ENST00000217320.3
TLDC2
TBC/LysM-associated domain containing 2
chr11_+_1295809 0.09 ENST00000598274.1
AC136297.1
Uncharacterized protein
chr6_+_134273321 0.09 ENST00000457715.1
TBPL1
TBP-like 1
chr1_+_86934526 0.08 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr12_+_113682066 0.08 ENST00000392569.4
ENST00000552542.1
TPCN1
two pore segment channel 1
chr6_+_31887761 0.08 ENST00000413154.1
C2
complement component 2
chrX_+_148622138 0.08 ENST00000450602.2
ENST00000441248.1
CXorf40A
chromosome X open reading frame 40A
chr3_+_49726932 0.08 ENST00000327697.6
ENST00000432042.1
ENST00000454491.1
RNF123
ring finger protein 123
chr19_-_5680202 0.08 ENST00000590389.1
C19orf70
chromosome 19 open reading frame 70
chrX_-_13835398 0.08 ENST00000475307.1
GPM6B
glycoprotein M6B
chr6_+_24495185 0.08 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr15_+_96904487 0.08 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr1_-_169680745 0.08 ENST00000236147.4
SELL
selectin L
chrX_-_13835147 0.08 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr7_-_141957847 0.08 ENST00000552471.1
ENST00000547058.2
PRSS58
protease, serine, 58
chrX_+_148622513 0.08 ENST00000393985.3
ENST00000423421.1
ENST00000423540.2
ENST00000434353.2
ENST00000514208.1
CXorf40A
chromosome X open reading frame 40A
chr2_+_27799389 0.07 ENST00000408964.2
C2orf16
chromosome 2 open reading frame 16
chr3_-_52719912 0.07 ENST00000420148.1
PBRM1
polybromo 1
chr8_+_26240666 0.07 ENST00000523949.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr2_+_96068436 0.07 ENST00000445649.1
ENST00000447036.1
ENST00000233379.4
ENST00000418606.1
FAHD2A
fumarylacetoacetate hydrolase domain containing 2A
chr19_+_6361795 0.07 ENST00000596149.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr8_-_7243080 0.07 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr19_+_6361841 0.07 ENST00000596605.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr17_-_42345487 0.07 ENST00000262418.6
SLC4A1
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr10_+_104535994 0.07 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr12_+_100867733 0.07 ENST00000546380.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr7_-_48068643 0.07 ENST00000453192.2
SUN3
Sad1 and UNC84 domain containing 3
chr17_-_79533608 0.07 ENST00000572760.1
ENST00000573876.1
NPLOC4
nuclear protein localization 4 homolog (S. cerevisiae)
chr3_+_52719936 0.07 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr10_-_5227096 0.07 ENST00000488756.1
ENST00000334314.3
AKR1CL1
aldo-keto reductase family 1, member C-like 1
chr19_-_9938480 0.07 ENST00000585379.1
FBXL12
F-box and leucine-rich repeat protein 12

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS3_TGIF2LX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 1.4 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.7 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.3 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.7 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.3 GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.5 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 1.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 0.3 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.3 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.0 GO:0032308 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.3 GO:0061151 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:2000625 rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 0.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.3 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.5 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.9 GO:0051608 histamine transport(GO:0051608)
0.0 0.2 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.2 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.2 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 1.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.3 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 0.2 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 2.1 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 1.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.0 GO:0045160 myosin I complex(GO:0045160)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 1.4 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.7 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.6 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.9 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.1 0.3 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0016594 glycine binding(GO:0016594)
0.0 0.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 1.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events