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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for MYBL1
Z-value: 1.66
Motif logo
Transcription factors associated with MYBL1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MYBL1
|
ENSG00000185697.12 | MYB proto-oncogene like 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYBL1 | hg19_v2_chr8_-_67525473_67525518 | 0.92 | 8.2e-09 | Click! |
Activity profile of MYBL1 motif
Sorted Z-values of MYBL1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MYBL1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.6 | GO:0042660 | positive regulation of cell fate specification(GO:0042660) |
| 1.2 | 6.2 | GO:0036343 | psychomotor behavior(GO:0036343) |
| 1.1 | 3.4 | GO:2000224 | sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224) |
| 0.9 | 2.6 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.8 | 3.3 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.8 | 2.5 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 0.6 | 1.8 | GO:0060827 | regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829) |
| 0.6 | 2.4 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.5 | 3.9 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.5 | 3.3 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.5 | 1.4 | GO:0046080 | dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081) |
| 0.5 | 1.4 | GO:1990426 | homologous recombination-dependent replication fork processing(GO:1990426) |
| 0.4 | 2.2 | GO:1903613 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.4 | 1.8 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.4 | 1.7 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.4 | 1.3 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.4 | 1.6 | GO:1990927 | negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927) |
| 0.4 | 1.1 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.3 | 3.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.3 | 1.3 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
| 0.3 | 1.6 | GO:1905040 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.3 | 0.9 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) RNA repair(GO:0042245) |
| 0.3 | 0.9 | GO:0060382 | regulation of DNA strand elongation(GO:0060382) |
| 0.3 | 1.5 | GO:0031296 | B cell costimulation(GO:0031296) |
| 0.3 | 2.9 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.3 | 1.1 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.3 | 1.7 | GO:0052199 | negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199) |
| 0.3 | 1.9 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 0.3 | 2.6 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.3 | 1.0 | GO:0016267 | O-glycan processing, core 1(GO:0016267) |
| 0.2 | 1.0 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.2 | 2.4 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.2 | 1.1 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.2 | 0.7 | GO:1904772 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 0.2 | 0.9 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.2 | 2.3 | GO:0042262 | DNA protection(GO:0042262) |
| 0.2 | 2.0 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.2 | 0.8 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.2 | 0.6 | GO:0051311 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 0.2 | 1.1 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.2 | 1.5 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.2 | 0.7 | GO:0090410 | malonate catabolic process(GO:0090410) |
| 0.2 | 4.1 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.2 | 1.1 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.2 | 4.1 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.2 | 1.4 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.1 | 0.4 | GO:2000397 | regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 0.1 | 1.6 | GO:0018317 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.1 | 1.1 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.1 | 0.5 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 0.1 | 1.8 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.1 | 3.0 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 0.4 | GO:0099543 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545) |
| 0.1 | 1.3 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 1.1 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 2.8 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.1 | 0.9 | GO:0046075 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 0.1 | 22.9 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.1 | 0.3 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.1 | 1.0 | GO:1904386 | response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386) |
| 0.1 | 3.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.3 | GO:0050822 | peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823) |
| 0.1 | 0.7 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.1 | 1.3 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 0.1 | 1.3 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.1 | 0.9 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.1 | 0.7 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.1 | 2.2 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.1 | 1.2 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 0.5 | GO:0009099 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.1 | 0.2 | GO:0009138 | pyrimidine nucleoside diphosphate metabolic process(GO:0009138) |
| 0.1 | 2.0 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 1.0 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.1 | 0.9 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 0.1 | 2.5 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.1 | 1.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.3 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.1 | 0.9 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.1 | 1.0 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.1 | 0.5 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.1 | 2.6 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 1.8 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.1 | 1.6 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.4 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.1 | 0.4 | GO:2001151 | regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153) |
| 0.1 | 0.2 | GO:1905033 | positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033) |
| 0.1 | 1.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 0.2 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 0.1 | 0.2 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
| 0.1 | 0.6 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.1 | 0.5 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 0.1 | 0.7 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 0.1 | 0.3 | GO:0097403 | cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) |
| 0.1 | 0.1 | GO:0016999 | antibiotic metabolic process(GO:0016999) |
| 0.1 | 1.2 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 0.4 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 0.4 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 0.1 | 0.6 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 4.6 | GO:0035307 | positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307) |
| 0.1 | 1.8 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 0.1 | 3.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 0.8 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.1 | 0.2 | GO:0043449 | cellular alkene metabolic process(GO:0043449) |
| 0.1 | 0.6 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 0.3 | GO:0030317 | sperm motility(GO:0030317) |
| 0.1 | 3.7 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.0 | 2.0 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 1.8 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 1.1 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.0 | 0.2 | GO:0007468 | regulation of rhodopsin gene expression(GO:0007468) |
| 0.0 | 0.8 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.0 | 1.5 | GO:1905145 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.0 | 0.9 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 0.2 | GO:0015883 | FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) |
| 0.0 | 0.8 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.6 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 0.2 | GO:0042144 | vacuole fusion, non-autophagic(GO:0042144) |
| 0.0 | 2.7 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.0 | 0.7 | GO:0003352 | regulation of cilium movement(GO:0003352) |
| 0.0 | 0.5 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.2 | GO:0046898 | response to cycloheximide(GO:0046898) cellular response to cycloheximide(GO:0071409) |
| 0.0 | 1.0 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 1.1 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.2 | GO:0043932 | ossification involved in bone remodeling(GO:0043932) |
| 0.0 | 0.4 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.0 | 0.1 | GO:0031938 | regulation of chromatin silencing at telomere(GO:0031938) |
| 0.0 | 0.6 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.0 | 0.2 | GO:0098908 | regulation of neuronal action potential(GO:0098908) |
| 0.0 | 1.8 | GO:0010259 | multicellular organism aging(GO:0010259) |
| 0.0 | 0.8 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 0.0 | 0.4 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.0 | 0.4 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.0 | 0.5 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 0.1 | GO:0046603 | negative regulation of mitotic centrosome separation(GO:0046603) |
| 0.0 | 0.2 | GO:0045007 | depurination(GO:0045007) |
| 0.0 | 1.4 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.0 | 0.2 | GO:0002729 | positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.0 | 1.4 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 0.6 | GO:0060285 | cilium-dependent cell motility(GO:0060285) |
| 0.0 | 1.2 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.0 | 0.9 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.0 | 1.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.0 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 8.4 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 0.6 | GO:0098780 | response to mitochondrial depolarisation(GO:0098780) |
| 0.0 | 1.8 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.0 | 1.1 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.0 | 0.1 | GO:0072720 | response to dithiothreitol(GO:0072720) |
| 0.0 | 0.1 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 0.0 | 1.6 | GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108) |
| 0.0 | 1.9 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.0 | 1.1 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.7 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.0 | 0.6 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.0 | 0.8 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 0.2 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 0.0 | 1.8 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 1.2 | GO:0042073 | intraciliary transport(GO:0042073) |
| 0.0 | 0.8 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.0 | 0.8 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.1 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.0 | 0.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.0 | 0.2 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.0 | 0.3 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 0.3 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.0 | 0.4 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 1.1 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.0 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 0.0 | 0.2 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.0 | 3.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.4 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.0 | 1.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 1.6 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.0 | 0.6 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.2 | GO:2001204 | regulation of osteoclast development(GO:2001204) |
| 0.0 | 0.4 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.4 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.0 | 0.4 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.2 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.0 | 0.3 | GO:0042135 | neurotransmitter catabolic process(GO:0042135) |
| 0.0 | 0.9 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
| 0.0 | 0.6 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 7.6 | GO:1990423 | RZZ complex(GO:1990423) |
| 1.1 | 7.4 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.7 | 3.4 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.6 | 1.8 | GO:0009346 | citrate lyase complex(GO:0009346) |
| 0.5 | 5.6 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.4 | 2.2 | GO:0097362 | MCM8-MCM9 complex(GO:0097362) |
| 0.4 | 1.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.4 | 2.5 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.4 | 1.7 | GO:0005712 | chiasma(GO:0005712) |
| 0.3 | 1.0 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.3 | 2.8 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.3 | 1.6 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.2 | 2.8 | GO:0000796 | condensin complex(GO:0000796) |
| 0.2 | 1.1 | GO:0031417 | NatC complex(GO:0031417) |
| 0.2 | 2.0 | GO:0033503 | HULC complex(GO:0033503) |
| 0.2 | 3.0 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.2 | 0.9 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.2 | 1.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.2 | 1.2 | GO:0030891 | VCB complex(GO:0030891) |
| 0.1 | 1.6 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 2.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 2.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 0.6 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.1 | 0.3 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.1 | 0.9 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.1 | 0.7 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.1 | 2.4 | GO:0000800 | lateral element(GO:0000800) |
| 0.1 | 2.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 3.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 13.9 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 1.3 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 3.7 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.1 | 1.6 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 0.9 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.1 | 2.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.1 | 0.5 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.1 | 0.9 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 0.2 | GO:0097636 | intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
| 0.1 | 4.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 0.9 | GO:0070187 | telosome(GO:0070187) |
| 0.1 | 1.2 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 0.5 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.1 | 6.1 | GO:0018995 | host(GO:0018995) host cell(GO:0043657) |
| 0.1 | 1.1 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 0.6 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 0.2 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
| 0.0 | 1.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 1.2 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 1.1 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.3 | GO:0042825 | TAP complex(GO:0042825) |
| 0.0 | 0.2 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.0 | 0.2 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.0 | 0.2 | GO:0044218 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 0.0 | 0.7 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 1.2 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 2.7 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.6 | GO:0045120 | pronucleus(GO:0045120) |
| 0.0 | 1.5 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.4 | GO:0097504 | SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504) |
| 0.0 | 0.6 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 1.1 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 0.9 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 1.0 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 1.0 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 3.0 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.9 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 1.2 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 2.8 | GO:0031970 | organelle envelope lumen(GO:0031970) |
| 0.0 | 1.9 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 1.8 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 1.6 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.9 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.1 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 0.5 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342) |
| 0.0 | 2.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.5 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 1.2 | GO:0044815 | DNA packaging complex(GO:0044815) |
| 0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 1.5 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.8 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.7 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 1.3 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 0.4 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 2.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.6 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.1 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.0 | 0.2 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.0 | 0.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.6 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.4 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.2 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 0.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.4 | GO:0047017 | geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017) |
| 0.6 | 1.9 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 0.6 | 1.9 | GO:0052894 | norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895) |
| 0.6 | 2.4 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.6 | 2.4 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.6 | 1.8 | GO:0003878 | ATP citrate synthase activity(GO:0003878) |
| 0.6 | 4.1 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.5 | 2.7 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.5 | 1.5 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.5 | 1.4 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 0.4 | 1.1 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.4 | 1.5 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.3 | 1.7 | GO:0070363 | mitochondrial light strand promoter sense binding(GO:0070363) |
| 0.3 | 1.0 | GO:0043337 | cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337) |
| 0.3 | 1.2 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.3 | 0.9 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
| 0.3 | 2.3 | GO:0030613 | oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) |
| 0.3 | 1.4 | GO:0031403 | lithium ion binding(GO:0031403) |
| 0.3 | 1.0 | GO:0016263 | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) |
| 0.2 | 1.4 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.2 | 0.9 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.2 | 1.3 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.2 | 0.6 | GO:0038131 | neuregulin receptor activity(GO:0038131) |
| 0.2 | 0.8 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.2 | 2.9 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.2 | 0.7 | GO:0090409 | malonyl-CoA synthetase activity(GO:0090409) |
| 0.2 | 4.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.2 | 0.9 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.2 | 1.2 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.2 | 3.5 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.1 | 0.6 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.1 | 0.4 | GO:1904854 | proteasome core complex binding(GO:1904854) |
| 0.1 | 2.0 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 1.6 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.1 | 1.6 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.1 | 1.1 | GO:0046790 | complement component C1q binding(GO:0001849) virion binding(GO:0046790) |
| 0.1 | 1.1 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.1 | 2.4 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.1 | 1.1 | GO:0003696 | satellite DNA binding(GO:0003696) |
| 0.1 | 0.3 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.1 | 1.3 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.1 | 1.1 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
| 0.1 | 0.5 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.1 | 1.4 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 0.5 | GO:0052656 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 0.9 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.1 | 1.8 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 0.8 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 0.5 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.1 | 0.7 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.1 | 2.8 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 0.8 | GO:0032407 | MutSalpha complex binding(GO:0032407) |
| 0.1 | 0.3 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.1 | 1.5 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.7 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 1.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 1.8 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 1.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 1.4 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.1 | 0.4 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.1 | 0.4 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 0.4 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.1 | 1.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.7 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.0 | 1.1 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 2.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.8 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.8 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 1.6 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 0.2 | GO:0015230 | FAD transmembrane transporter activity(GO:0015230) |
| 0.0 | 0.8 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.0 | 0.9 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.0 | 1.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.4 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.0 | 2.6 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.4 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.0 | 1.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 1.4 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 2.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 2.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.7 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.0 | 0.2 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.0 | 1.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.3 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.0 | 1.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 1.2 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.7 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.0 | 0.7 | GO:0015036 | disulfide oxidoreductase activity(GO:0015036) |
| 0.0 | 0.4 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.3 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 4.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 2.0 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.2 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.2 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 0.0 | 6.3 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 5.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 0.2 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 0.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 0.2 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.0 | 1.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.2 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 0.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 2.8 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.4 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.4 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.1 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 1.9 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 0.7 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.8 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 0.2 | GO:0031543 | peptidyl-proline dioxygenase activity(GO:0031543) |
| 0.0 | 1.6 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.3 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.0 | 0.2 | GO:0010181 | FMN binding(GO:0010181) |
| 0.0 | 0.4 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.0 | 0.2 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 3.9 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 1.0 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.1 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.7 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.3 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.2 | 4.1 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 5.3 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 1.6 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 1.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 1.6 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.0 | 1.6 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.1 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.0 | 1.1 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 1.5 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 3.8 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 3.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 1.8 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 2.4 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 2.6 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 2.6 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 4.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.8 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 2.1 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 1.9 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.0 | 0.6 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.1 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 1.1 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.0 | 1.0 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.2 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 2.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.6 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.2 | 26.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 2.2 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.1 | 2.0 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 1.1 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.1 | 3.1 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 2.5 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.1 | 4.1 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 1.9 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 5.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 2.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 1.8 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 2.4 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 1.1 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 1.3 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 5.1 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 0.7 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 1.4 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 1.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.2 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.4 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 2.4 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 1.4 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.4 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 1.2 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 2.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.6 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 1.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 1.6 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.5 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.0 | 0.5 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.4 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 2.2 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 0.5 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 0.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 1.4 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.6 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 0.7 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 1.3 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.4 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.2 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.0 | 0.2 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.4 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.6 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.0 | 0.4 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 3.4 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.2 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 3.1 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 1.0 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |