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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFAT5

Z-value: 0.70

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Transcription factors associated with NFAT5

Gene Symbol Gene ID Gene Info
NFAT5
ENSG00000102908.16 nuclear factor of activated T cells 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFAT5hg19_v2_chr16_+_69600209_69600254-0.802.2e-05Click!

Activity profile of NFAT5 motif

Sorted Z-values of NFAT5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_23731893 2.18 ENST00000398402.1
CST1
cystatin SN
chr4_-_155511887 1.88 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr11_+_65190245 1.88 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr14_+_103589789 1.66 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr20_-_23731569 1.64 ENST00000304749.2
CST1
cystatin SN
chr19_+_859425 1.56 ENST00000327726.6
CFD
complement factor D (adipsin)
chr12_+_120502441 1.35 ENST00000446727.2
CCDC64
coiled-coil domain containing 64
chr19_+_48828788 1.30 ENST00000594198.1
ENST00000597279.1
ENST00000593437.1
EMP3
epithelial membrane protein 3
chr19_+_48828582 1.18 ENST00000270221.6
ENST00000596315.1
EMP3
epithelial membrane protein 3
chr11_-_8190534 1.04 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
RIC3
RIC3 acetylcholine receptor chaperone
chr11_-_67120974 1.03 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr19_+_45254529 1.00 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr16_+_2079637 0.95 ENST00000561844.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr14_-_103589246 0.93 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr16_+_2079501 0.91 ENST00000563587.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr3_+_49027308 0.91 ENST00000383729.4
ENST00000343546.4
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr2_-_20101385 0.90 ENST00000431392.1
TTC32
tetratricopeptide repeat domain 32
chr17_+_6915730 0.89 ENST00000548577.1
RNASEK
ribonuclease, RNase K
chr1_-_153517473 0.82 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr14_+_100594914 0.78 ENST00000554695.1
EVL
Enah/Vasp-like
chr9_-_4859260 0.76 ENST00000599351.1
AL158147.2
HCG2011465; Uncharacterized protein
chr17_-_38545799 0.74 ENST00000577541.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr6_+_89790490 0.71 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_18958008 0.71 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr17_+_25799008 0.70 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr22_+_23248512 0.68 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr22_+_23243156 0.65 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chrX_+_12993202 0.65 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr17_-_202579 0.60 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL
rabphilin 3A-like (without C2 domains)
chr11_+_65154070 0.58 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr17_+_4853442 0.58 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr14_+_95078714 0.56 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr11_-_2924970 0.55 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr8_-_27469196 0.55 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr5_-_137090028 0.54 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr12_+_69742121 0.53 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr3_+_9834227 0.52 ENST00000287613.7
ENST00000397261.3
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr19_+_49999631 0.52 ENST00000270625.2
ENST00000596873.1
ENST00000594493.1
ENST00000599561.1
RPS11
ribosomal protein S11
chr17_+_68071389 0.52 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chrX_+_70752917 0.51 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_+_143635067 0.51 ENST00000264170.4
KYNU
kynureninase
chr19_+_3178736 0.51 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr6_+_138188351 0.51 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr3_+_184079492 0.50 ENST00000456318.1
ENST00000412877.1
ENST00000438240.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr15_-_102285007 0.50 ENST00000560292.2
RP11-89K11.1
Uncharacterized protein
chr1_-_155006224 0.50 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr16_-_51185149 0.49 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chr12_+_22778291 0.48 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr1_-_57045228 0.48 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr6_+_89790459 0.47 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr3_-_9834375 0.46 ENST00000343450.2
ENST00000301964.2
TADA3
transcriptional adaptor 3
chr21_+_17792672 0.46 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr4_-_74847800 0.46 ENST00000296029.3
PF4
platelet factor 4
chr1_-_155006254 0.45 ENST00000295536.5
DCST2
DC-STAMP domain containing 2
chr20_+_33104199 0.45 ENST00000357156.2
ENST00000417166.2
ENST00000300469.9
ENST00000374846.3
DYNLRB1
dynein, light chain, roadblock-type 1
chrX_+_48755183 0.44 ENST00000376563.1
ENST00000376566.4
PQBP1
polyglutamine binding protein 1
chr3_-_156878540 0.44 ENST00000461804.1
CCNL1
cyclin L1
chr3_+_8543561 0.42 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr17_+_68071458 0.42 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr20_-_19738569 0.42 ENST00000598007.1
AL121761.2
Uncharacterized protein
chr17_-_46716647 0.42 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr19_+_44037546 0.41 ENST00000601282.1
ZNF575
zinc finger protein 575
chr6_+_138188551 0.41 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chrX_+_135579670 0.41 ENST00000218364.4
HTATSF1
HIV-1 Tat specific factor 1
chr17_+_45908974 0.39 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr15_-_75134992 0.39 ENST00000568667.1
ULK3
unc-51 like kinase 3
chrX_-_128977781 0.38 ENST00000357166.6
ZDHHC9
zinc finger, DHHC-type containing 9
chr4_+_105828492 0.37 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr14_-_25479811 0.37 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr15_+_100348193 0.36 ENST00000558188.1
CTD-2054N24.2
Uncharacterized protein
chr19_-_46285736 0.36 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr13_-_50265570 0.35 ENST00000378270.5
ENST00000378284.2
ENST00000378272.5
ENST00000378268.1
ENST00000242827.6
ENST00000378282.5
EBPL
emopamil binding protein-like
chr11_-_58612168 0.33 ENST00000287275.1
GLYATL2
glycine-N-acyltransferase-like 2
chr7_+_96634850 0.33 ENST00000518156.2
DLX6
distal-less homeobox 6
chr9_-_34589700 0.33 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr14_+_91581011 0.33 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr18_+_11103 0.32 ENST00000575820.1
ENST00000572573.1
AP005530.1
AP005530.1
chr14_-_60097297 0.32 ENST00000395090.1
RTN1
reticulon 1
chr3_+_77088989 0.32 ENST00000461745.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr11_-_75062730 0.32 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr16_+_30968615 0.32 ENST00000262519.8
SETD1A
SET domain containing 1A
chr4_+_105828537 0.31 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr10_+_89419370 0.31 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr14_+_100848311 0.31 ENST00000542471.2
WDR25
WD repeat domain 25
chr7_+_149570049 0.31 ENST00000421974.2
ENST00000456496.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr20_-_23807358 0.31 ENST00000304725.2
CST2
cystatin SA
chr1_-_246670519 0.31 ENST00000388985.4
ENST00000490107.1
SMYD3
SET and MYND domain containing 3
chr12_+_53848549 0.31 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr19_-_12792020 0.30 ENST00000594424.1
ENST00000597152.1
ENST00000596162.1
DHPS
deoxyhypusine synthase
chr19_-_47288162 0.30 ENST00000594991.1
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr4_-_83483395 0.30 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr3_+_47866490 0.29 ENST00000457607.1
DHX30
DEAH (Asp-Glu-Ala-His) box helicase 30
chr14_+_91580777 0.29 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr10_-_124639062 0.29 ENST00000368898.3
ENST00000368896.1
ENST00000545804.1
FAM24B
CUZD1
family with sequence similarity 24, member B
CUB and zona pellucida-like domains 1
chr14_+_97059070 0.29 ENST00000553378.1
ENST00000555496.1
RP11-433J8.1
RP11-433J8.1
chr12_+_53848505 0.29 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chr12_+_10365404 0.29 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr17_-_40950698 0.29 ENST00000328434.7
COA3
cytochrome c oxidase assembly factor 3
chr11_+_8932828 0.28 ENST00000530281.1
ENST00000396648.2
ENST00000534147.1
ENST00000529942.1
AKIP1
A kinase (PRKA) interacting protein 1
chr22_+_24551765 0.28 ENST00000337989.7
CABIN1
calcineurin binding protein 1
chr2_+_56179262 0.27 ENST00000606639.1
RP11-481J13.1
RP11-481J13.1
chr8_-_133772870 0.27 ENST00000522334.1
ENST00000519016.1
TMEM71
transmembrane protein 71
chr7_-_100888313 0.27 ENST00000442303.1
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr13_+_113030658 0.27 ENST00000414180.1
ENST00000443541.1
SPACA7
sperm acrosome associated 7
chr8_-_133772794 0.26 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71
transmembrane protein 71
chr6_+_152011628 0.26 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr7_-_102119342 0.26 ENST00000393794.3
ENST00000292614.5
POLR2J
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr12_+_110011571 0.26 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr14_-_102706934 0.26 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
MOK
MOK protein kinase
chr14_+_91580708 0.25 ENST00000518868.1
C14orf159
chromosome 14 open reading frame 159
chr3_-_9834463 0.25 ENST00000439043.1
TADA3
transcriptional adaptor 3
chr9_+_139921916 0.24 ENST00000314330.2
C9orf139
chromosome 9 open reading frame 139
chr5_+_140186647 0.24 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr1_-_246670614 0.24 ENST00000403792.3
SMYD3
SET and MYND domain containing 3
chr12_+_101988774 0.24 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr8_+_132320792 0.24 ENST00000519695.1
ENST00000524275.1
CTD-2501M5.1
CTD-2501M5.1
chr5_-_41261540 0.23 ENST00000263413.3
C6
complement component 6
chr9_-_80263220 0.22 ENST00000341700.6
GNA14
guanine nucleotide binding protein (G protein), alpha 14
chrX_-_45060135 0.22 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr6_+_41755389 0.22 ENST00000398884.3
ENST00000398881.3
TOMM6
translocase of outer mitochondrial membrane 6 homolog (yeast)
chr3_-_42003613 0.22 ENST00000414606.1
ULK4
unc-51 like kinase 4
chr10_+_135122906 0.21 ENST00000368554.4
ZNF511
zinc finger protein 511
chr1_+_111889212 0.21 ENST00000369737.4
PIFO
primary cilia formation
chr14_+_91580732 0.21 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
C14orf159
chromosome 14 open reading frame 159
chr15_+_54901540 0.21 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr11_+_60145948 0.21 ENST00000300184.3
ENST00000358246.1
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr17_-_38083843 0.21 ENST00000304046.2
ENST00000579695.1
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr8_-_27469383 0.20 ENST00000519742.1
CLU
clusterin
chr14_+_39644425 0.19 ENST00000556530.1
PNN
pinin, desmosome associated protein
chr12_-_78934441 0.19 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
RP11-171L9.1
chr6_+_73331776 0.19 ENST00000370398.1
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr7_+_141478242 0.19 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr17_+_40950900 0.18 ENST00000588527.1
CNTD1
cyclin N-terminal domain containing 1
chr7_-_123673471 0.18 ENST00000455783.1
TMEM229A
transmembrane protein 229A
chr16_+_10971037 0.18 ENST00000324288.8
ENST00000381835.5
CIITA
class II, major histocompatibility complex, transactivator
chr11_+_119039414 0.18 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLRX1
NLR family member X1
chr19_+_17420340 0.18 ENST00000359866.4
DDA1
DET1 and DDB1 associated 1
chr7_+_95401851 0.18 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr10_-_97175444 0.18 ENST00000486141.2
SORBS1
sorbin and SH3 domain containing 1
chr16_-_51185172 0.18 ENST00000251020.4
SALL1
spalt-like transcription factor 1
chr3_+_97851542 0.18 ENST00000354565.2
OR5H1
olfactory receptor, family 5, subfamily H, member 1
chr14_-_60097524 0.18 ENST00000342503.4
RTN1
reticulon 1
chr3_+_8543393 0.17 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr5_-_77844974 0.17 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr17_+_17991197 0.17 ENST00000225729.3
DRG2
developmentally regulated GTP binding protein 2
chr5_-_35230771 0.17 ENST00000342362.5
PRLR
prolactin receptor
chr5_-_96209315 0.17 ENST00000504056.1
CTD-2260A17.2
Uncharacterized protein
chr14_+_91580357 0.16 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
C14orf159
chromosome 14 open reading frame 159
chr18_-_52989525 0.16 ENST00000457482.3
TCF4
transcription factor 4
chr2_-_26569611 0.16 ENST00000541401.1
ENST00000433584.1
ENST00000333478.6
GPR113
G protein-coupled receptor 113
chr11_-_74800799 0.16 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr6_+_30103885 0.16 ENST00000396581.1
TRIM40
tripartite motif containing 40
chr19_+_14142535 0.16 ENST00000263379.2
IL27RA
interleukin 27 receptor, alpha
chrX_+_18725758 0.16 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chrX_-_130964596 0.16 ENST00000427391.1
RP11-453F18__B.1
RP11-453F18__B.1
chr6_-_44400720 0.16 ENST00000595057.1
AL133262.1
AL133262.1
chr3_-_42003479 0.16 ENST00000420927.1
ULK4
unc-51 like kinase 4
chr3_+_63805017 0.16 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chr7_-_92855762 0.15 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr2_-_68479614 0.15 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr17_+_6658878 0.15 ENST00000574394.1
XAF1
XIAP associated factor 1
chr11_+_128563652 0.15 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_-_11287243 0.15 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr22_-_28490123 0.15 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr12_+_26274917 0.15 ENST00000538142.1
SSPN
sarcospan
chr2_+_200820494 0.15 ENST00000435773.2
C2orf47
chromosome 2 open reading frame 47
chr12_-_82152444 0.14 ENST00000549325.1
ENST00000550584.2
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr5_+_140261703 0.14 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr16_-_65268795 0.14 ENST00000565901.1
ENST00000567058.1
RP11-256I9.2
RP11-256I9.2
chr17_-_46608272 0.14 ENST00000577092.1
ENST00000239174.6
HOXB1
homeobox B1
chr3_+_8543533 0.13 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr12_+_101988627 0.13 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr11_+_60635035 0.13 ENST00000278853.5
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr2_-_238305397 0.13 ENST00000409809.1
COL6A3
collagen, type VI, alpha 3
chr1_-_6259641 0.13 ENST00000234875.4
RPL22
ribosomal protein L22
chr11_+_60145997 0.13 ENST00000530614.1
ENST00000530027.1
ENST00000530234.2
ENST00000528215.1
ENST00000531787.1
MS4A7
MS4A14
membrane-spanning 4-domains, subfamily A, member 7
membrane-spanning 4-domains, subfamily A, member 14
chr17_-_15466850 0.12 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
TVP23C
TVP23C-CDRT4
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr12_+_10365082 0.12 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr16_-_85969774 0.12 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr19_-_44100275 0.12 ENST00000422989.1
ENST00000598324.1
IRGQ
immunity-related GTPase family, Q
chr6_-_134495992 0.12 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_155006300 0.12 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr7_-_99698338 0.12 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr18_-_52989217 0.12 ENST00000570287.2
TCF4
transcription factor 4
chr10_-_63995871 0.12 ENST00000315289.2
RTKN2
rhotekin 2
chr11_-_75062829 0.11 ENST00000393505.4
ARRB1
arrestin, beta 1
chr11_-_18063973 0.11 ENST00000528338.1
TPH1
tryptophan hydroxylase 1
chr12_-_108991778 0.11 ENST00000549447.1
TMEM119
transmembrane protein 119
chr12_+_69139886 0.11 ENST00000398004.2
SLC35E3
solute carrier family 35, member E3
chr4_+_122685691 0.11 ENST00000424958.1
AC079341.1
Uncharacterized protein
chr9_+_95909309 0.11 ENST00000366188.2
RP11-370F5.4
RP11-370F5.4
chr12_-_11214893 0.11 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr1_-_169599314 0.10 ENST00000367786.2
ENST00000458599.2
ENST00000367795.2
ENST00000263686.6
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr22_-_38380543 0.10 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr20_-_44176013 0.10 ENST00000555685.1
EPPIN
epididymal peptidase inhibitor
chr8_-_7243080 0.10 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr1_+_111888890 0.10 ENST00000369738.4
PIFO
primary cilia formation
chr2_-_207078086 0.10 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr1_-_36945097 0.09 ENST00000331941.5
ENST00000418048.2
ENST00000338937.5
ENST00000440588.2
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr5_-_133747589 0.08 ENST00000458198.2
CDKN2AIPNL
CDKN2A interacting protein N-terminal like

Network of associatons between targets according to the STRING database.

First level regulatory network of NFAT5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.3 0.9 GO:2000349 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 4.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.7 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 1.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 2.0 GO:0051601 exocyst localization(GO:0051601)
0.1 0.8 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 2.5 GO:0032060 bleb assembly(GO:0032060)
0.1 0.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.5 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.3 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.7 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 1.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.3 GO:0046203 spermidine catabolic process(GO:0046203)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.0 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 1.0 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.5 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.0 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 1.2 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.9 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.6 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.8 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.7 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 1.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.5 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 1.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 2.0 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.7 GO:0030914 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 2.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 1.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.3 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.5 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 4.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.8 GO:0005522 profilin binding(GO:0005522)
0.0 0.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0043208 fucose binding(GO:0042806) glycosphingolipid binding(GO:0043208)
0.0 2.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 5.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules