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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFATC1

Z-value: 1.03

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Transcription factors associated with NFATC1

Gene Symbol Gene ID Gene Info
NFATC1
ENSG00000131196.13 nuclear factor of activated T cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC1hg19_v2_chr18_+_77155942_77155951-0.732.3e-04Click!

Activity profile of NFATC1 motif

Sorted Z-values of NFATC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39781054 6.51 ENST00000463128.1
KRT17
keratin 17
chr12_-_52887034 6.45 ENST00000330722.6
KRT6A
keratin 6A
chr17_-_39780819 6.36 ENST00000311208.8
KRT17
keratin 17
chr17_-_39780634 5.95 ENST00000577817.2
KRT17
keratin 17
chr1_+_46640750 4.97 ENST00000372003.1
TSPAN1
tetraspanin 1
chr17_-_39743139 4.40 ENST00000167586.6
KRT14
keratin 14
chr2_-_230786032 3.78 ENST00000428959.1
TRIP12
thyroid hormone receptor interactor 12
chr12_-_28125638 3.15 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr17_-_39677971 3.15 ENST00000393976.2
KRT15
keratin 15
chr12_-_50616122 3.09 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr17_-_39216344 3.08 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr3_-_111314230 3.05 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr12_-_50616382 2.86 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr11_+_34642656 2.76 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr1_-_27816556 2.61 ENST00000536657.1
WASF2
WAS protein family, member 2
chr18_+_29027696 2.54 ENST00000257189.4
DSG3
desmoglein 3
chr7_-_38969150 2.40 ENST00000418457.2
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chrX_-_84634708 2.37 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr21_-_35899113 2.30 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr15_+_93443419 2.26 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr2_+_75061108 2.16 ENST00000290573.2
HK2
hexokinase 2
chr5_-_78808617 2.15 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr8_-_124553437 2.10 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr13_+_73629107 2.07 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr2_-_230786378 2.06 ENST00000430954.1
TRIP12
thyroid hormone receptor interactor 12
chr8_+_95653302 2.00 ENST00000423620.2
ENST00000433389.2
ESRP1
epithelial splicing regulatory protein 1
chr14_-_69261310 1.97 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr6_-_56716686 1.97 ENST00000520645.1
DST
dystonin
chr12_-_13529642 1.69 ENST00000318426.2
C12orf36
chromosome 12 open reading frame 36
chr4_-_80994619 1.67 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr6_-_128841503 1.66 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr2_+_17721920 1.66 ENST00000295156.4
VSNL1
visinin-like 1
chr11_-_110167331 1.65 ENST00000534683.1
RDX
radixin
chr5_-_39203093 1.59 ENST00000515010.1
FYB
FYN binding protein
chr11_+_131240373 1.56 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chr3_-_71632894 1.56 ENST00000493089.1
FOXP1
forkhead box P1
chr7_-_80548493 1.55 ENST00000536800.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr17_+_36584662 1.52 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr8_+_95653427 1.50 ENST00000454170.2
ESRP1
epithelial splicing regulatory protein 1
chr11_-_102668879 1.49 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr8_+_95653373 1.48 ENST00000358397.5
ESRP1
epithelial splicing regulatory protein 1
chr7_+_55177416 1.47 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr3_+_152017924 1.46 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chr11_+_10477733 1.45 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr10_-_27149851 1.44 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
ABI1
abl-interactor 1
chr1_+_150254936 1.43 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr1_-_111743285 1.41 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr2_-_161349909 1.38 ENST00000392753.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr14_+_35591509 1.37 ENST00000604073.1
KIAA0391
KIAA0391
chr15_-_35280426 1.37 ENST00000559564.1
ENST00000356321.4
ZNF770
zinc finger protein 770
chr15_+_52155001 1.35 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr5_+_148521046 1.35 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3
actin binding LIM protein family, member 3
chr11_+_34654011 1.35 ENST00000531794.1
EHF
ets homologous factor
chr11_-_110167352 1.35 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr3_+_107364769 1.33 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr10_-_27149904 1.32 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
ABI1
abl-interactor 1
chr1_+_117963209 1.32 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr4_+_169633310 1.31 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chrX_+_41193407 1.30 ENST00000457138.2
ENST00000441189.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr3_+_133293278 1.29 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3
CDV3 homolog (mouse)
chr11_-_122929699 1.27 ENST00000526686.1
HSPA8
heat shock 70kDa protein 8
chr6_+_163837347 1.26 ENST00000544436.1
QKI
QKI, KH domain containing, RNA binding
chr3_-_141747439 1.26 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_+_131240593 1.26 ENST00000539799.1
NTM
neurotrimin
chr11_+_19798964 1.24 ENST00000527559.2
NAV2
neuron navigator 2
chr3_+_185304059 1.23 ENST00000427465.2
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr1_+_61548374 1.23 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chr4_+_154387480 1.20 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr1_-_161337662 1.19 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr7_-_105319536 1.18 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr1_-_36020531 1.16 ENST00000440579.1
ENST00000494948.1
KIAA0319L
KIAA0319-like
chr7_-_83824449 1.15 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_+_148521136 1.14 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chr3_-_69370095 1.14 ENST00000473029.1
FRMD4B
FERM domain containing 4B
chr14_+_72064945 1.14 ENST00000537413.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr10_-_27149792 1.13 ENST00000376140.3
ENST00000376170.4
ABI1
abl-interactor 1
chr13_-_99667960 1.12 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr12_+_96588279 1.11 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr21_-_16374688 1.09 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr5_-_73937244 1.09 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr11_-_122930121 1.08 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr2_-_172087824 1.08 ENST00000521943.1
TLK1
tousled-like kinase 1
chr3_-_119813264 1.06 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr5_+_49962772 1.03 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr9_-_71869642 1.03 ENST00000600472.1
AL358113.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr11_-_13461790 1.02 ENST00000530907.1
BTBD10
BTB (POZ) domain containing 10
chr11_-_14358620 1.02 ENST00000531421.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr20_+_36149602 1.01 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr8_+_92082424 1.01 ENST00000285420.4
ENST00000404789.3
OTUD6B
OTU domain containing 6B
chr10_-_79789291 0.99 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr4_+_160203650 0.99 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_61547405 0.99 ENST00000371189.4
NFIA
nuclear factor I/A
chr4_-_100356291 0.99 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_-_13529594 0.98 ENST00000539026.1
C12orf36
chromosome 12 open reading frame 36
chr3_+_177159695 0.98 ENST00000442937.1
LINC00578
long intergenic non-protein coding RNA 578
chr1_-_154164534 0.98 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr10_+_11206925 0.98 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr6_-_138866823 0.97 ENST00000342260.5
NHSL1
NHS-like 1
chr8_+_95653840 0.96 ENST00000520385.1
ESRP1
epithelial splicing regulatory protein 1
chr15_-_43785274 0.96 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr1_+_209941942 0.95 ENST00000487271.1
ENST00000477431.1
TRAF3IP3
TRAF3 interacting protein 3
chr2_+_201242715 0.95 ENST00000421573.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr1_+_15853308 0.95 ENST00000375838.1
ENST00000375847.3
ENST00000375849.1
DNAJC16
DnaJ (Hsp40) homolog, subfamily C, member 16
chrX_-_19905577 0.94 ENST00000379697.3
SH3KBP1
SH3-domain kinase binding protein 1
chr11_-_102651343 0.94 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr5_+_49963239 0.94 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr4_-_80994471 0.94 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chrX_-_84634737 0.93 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr11_+_19799327 0.92 ENST00000540292.1
NAV2
neuron navigator 2
chr2_-_214016314 0.92 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr7_+_134551583 0.92 ENST00000435928.1
CALD1
caldesmon 1
chr1_-_50889155 0.91 ENST00000404795.3
DMRTA2
DMRT-like family A2
chr19_-_4722780 0.90 ENST00000600621.1
DPP9
dipeptidyl-peptidase 9
chr9_+_22646189 0.90 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr15_-_59981479 0.90 ENST00000607373.1
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr20_-_50808236 0.90 ENST00000361387.2
ZFP64
ZFP64 zinc finger protein
chr12_+_46777450 0.88 ENST00000551503.1
RP11-96H19.1
RP11-96H19.1
chr3_-_71353892 0.87 ENST00000484350.1
FOXP1
forkhead box P1
chr4_+_146403912 0.87 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr3_+_63897605 0.86 ENST00000487717.1
ATXN7
ataxin 7
chr10_+_129785536 0.84 ENST00000419012.2
PTPRE
protein tyrosine phosphatase, receptor type, E
chr3_+_107364683 0.83 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr14_+_32547434 0.83 ENST00000556191.1
ENST00000554090.1
ARHGAP5
Rho GTPase activating protein 5
chr17_-_40264321 0.82 ENST00000430773.1
ENST00000413196.2
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr14_+_90864504 0.82 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_78354243 0.79 ENST00000294624.8
NEXN
nexilin (F actin binding protein)
chr1_+_39670423 0.79 ENST00000536367.1
MACF1
microtubule-actin crosslinking factor 1
chr12_+_96588143 0.79 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr13_-_108867101 0.79 ENST00000356922.4
LIG4
ligase IV, DNA, ATP-dependent
chr11_-_71752100 0.79 ENST00000542977.1
NUMA1
nuclear mitotic apparatus protein 1
chr3_-_111852061 0.78 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr4_+_39046615 0.77 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr9_+_124062071 0.76 ENST00000373818.4
GSN
gelsolin
chr11_+_11863500 0.75 ENST00000527733.1
ENST00000539466.1
USP47
ubiquitin specific peptidase 47
chr12_+_27396901 0.75 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr12_+_96588368 0.75 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr5_+_33440802 0.75 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
TARS
threonyl-tRNA synthetase
chr12_+_69201923 0.75 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr9_-_136006496 0.75 ENST00000372062.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr10_-_65028817 0.74 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr5_+_33441053 0.74 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
TARS
threonyl-tRNA synthetase
chr6_+_15246501 0.73 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr6_-_119670919 0.73 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr10_+_13141585 0.73 ENST00000378764.2
OPTN
optineurin
chr7_-_83824169 0.72 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_109915098 0.69 ENST00000542858.1
ENST00000542262.1
ENST00000424763.2
KCTD10
potassium channel tetramerization domain containing 10
chr3_-_111852128 0.69 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr6_+_106534192 0.69 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr4_-_153274078 0.69 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr10_+_13141441 0.68 ENST00000263036.5
OPTN
optineurin
chr5_+_179125368 0.67 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
CANX
calnexin
chr13_-_49975632 0.67 ENST00000457041.1
ENST00000355854.4
CAB39L
calcium binding protein 39-like
chr14_-_89883412 0.66 ENST00000557258.1
FOXN3
forkhead box N3
chr12_+_26205496 0.65 ENST00000537946.1
ENST00000541218.1
ENST00000282884.9
ENST00000545413.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr18_-_53257027 0.65 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4
transcription factor 4
chr4_+_159131630 0.63 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr1_+_61548225 0.63 ENST00000371187.3
NFIA
nuclear factor I/A
chr11_-_129062093 0.62 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr10_-_27443294 0.62 ENST00000396296.3
ENST00000375972.3
ENST00000376016.3
ENST00000491542.2
YME1L1
YME1-like 1 ATPase
chrX_+_102611373 0.62 ENST00000372661.3
ENST00000372656.3
WBP5
WW domain binding protein 5
chr3_-_178789220 0.62 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr11_+_64950801 0.62 ENST00000526468.1
CAPN1
calpain 1, (mu/I) large subunit
chr10_-_65028938 0.62 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr17_+_27047570 0.61 ENST00000472628.1
ENST00000578181.1
RPL23A
ribosomal protein L23a
chr13_-_99174252 0.61 ENST00000376547.3
STK24
serine/threonine kinase 24
chr5_+_38445641 0.60 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr10_+_13142075 0.60 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr19_+_41509851 0.59 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr3_-_141747459 0.59 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_40862501 0.58 ENST00000539317.1
SMAP2
small ArfGAP2
chr11_-_111794446 0.57 ENST00000527950.1
CRYAB
crystallin, alpha B
chr3_+_141596371 0.57 ENST00000495216.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr15_+_73976545 0.57 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276
CD276 molecule
chr3_+_69134080 0.57 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr12_+_104359641 0.57 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr12_-_117799446 0.57 ENST00000317775.6
ENST00000344089.3
NOS1
nitric oxide synthase 1 (neuronal)
chr9_-_14314518 0.56 ENST00000397581.2
NFIB
nuclear factor I/B
chr5_+_118691008 0.56 ENST00000504642.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr8_+_128748466 0.56 ENST00000524013.1
ENST00000520751.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr1_-_94703118 0.55 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr12_-_112037306 0.54 ENST00000535949.1
ENST00000542287.2
ENST00000377617.3
ENST00000550104.1
ATXN2
ataxin 2
chr20_-_50808290 0.54 ENST00000346617.4
ENST00000371515.4
ENST00000371518.2
ZFP64
ZFP64 zinc finger protein
chr9_+_129097479 0.54 ENST00000402437.2
MVB12B
multivesicular body subunit 12B
chr12_+_104359614 0.53 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr12_+_26111823 0.53 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr9_-_132597529 0.53 ENST00000372447.3
C9orf78
chromosome 9 open reading frame 78
chr2_+_11817713 0.53 ENST00000449576.2
LPIN1
lipin 1
chr9_-_14314566 0.53 ENST00000397579.2
NFIB
nuclear factor I/B
chr18_-_53089723 0.53 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr17_+_46018872 0.53 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
PNPO
pyridoxamine 5'-phosphate oxidase
chr8_+_38831683 0.52 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr11_-_2182388 0.52 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
INS
INS-IGF2
insulin
INS-IGF2 readthrough
chr12_+_11802753 0.52 ENST00000396373.4
ETV6
ets variant 6
chr20_-_50808525 0.52 ENST00000216923.4
ZFP64
ZFP64 zinc finger protein
chr1_-_151798546 0.51 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr1_-_43638168 0.51 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr2_+_46926326 0.50 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr20_-_43589109 0.50 ENST00000372813.3
TOMM34
translocase of outer mitochondrial membrane 34
chr1_-_156051789 0.50 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr19_+_16222678 0.50 ENST00000586682.1
RAB8A
RAB8A, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.4 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.8 23.2 GO:0045109 intermediate filament organization(GO:0045109)
0.6 2.4 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.6 5.8 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.5 2.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.5 1.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.5 3.0 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.5 2.3 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.5 1.9 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.4 2.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.4 2.0 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.4 1.5 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.4 1.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.3 1.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.3 1.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3 2.2 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 2.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 1.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 1.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.3 0.8 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.2 0.7 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 1.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 2.2 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.2 2.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 2.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.4 GO:0006196 AMP catabolic process(GO:0006196)
0.2 0.6 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 6.6 GO:0035855 megakaryocyte development(GO:0035855)
0.2 0.6 GO:0099543 positive regulation of adrenergic receptor signaling pathway(GO:0071879) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.2 0.6 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.2 0.5 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.2 0.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 1.3 GO:0042256 mature ribosome assembly(GO:0042256) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.2 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 1.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 1.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.8 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 1.5 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.0 GO:0019075 virus maturation(GO:0019075)
0.1 1.0 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 1.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.6 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.7 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 1.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.8 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.4 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 2.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.6 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 2.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.4 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 1.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 1.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.3 GO:0051795 apoptotic process involved in outflow tract morphogenesis(GO:0003275) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 1.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.5 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 1.0 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.3 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.1 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.1 0.2 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.4 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.2 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.6 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.0 GO:0009249 protein lipoylation(GO:0009249)
0.1 5.3 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 2.8 GO:0060074 synapse maturation(GO:0060074)
0.1 1.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.5 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.5 GO:0070836 caveola assembly(GO:0070836)
0.1 0.9 GO:0051149 positive regulation of muscle cell differentiation(GO:0051149)
0.1 0.2 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.9 GO:0002076 osteoblast development(GO:0002076)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 2.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 1.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.6 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353) homocysteine catabolic process(GO:0043418)
0.0 0.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.4 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 2.9 GO:0008038 neuron recognition(GO:0008038)
0.0 2.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.5 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 8.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 1.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 1.2 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 1.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0042335 cuticle development(GO:0042335)
0.0 3.2 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.6 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.5 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.6 GO:0007379 segment specification(GO:0007379)
0.0 0.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.0 GO:0061145 primary prostatic bud elongation(GO:0060516) bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 2.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.0 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 4.3 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487) regulation of enamel mineralization(GO:0070173)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 4.4 GO:0050821 protein stabilization(GO:0050821)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 2.3 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 1.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 1.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.4 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 1.4 GO:0060348 bone development(GO:0060348)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.8 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.7 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.4 6.5 GO:0031209 SCAR complex(GO:0031209)
0.3 2.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.3 2.0 GO:0031673 H zone(GO:0031673)
0.3 3.0 GO:0051286 cell tip(GO:0051286)
0.3 2.6 GO:0033263 CORVET complex(GO:0033263)
0.2 1.8 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 6.0 GO:0030057 desmosome(GO:0030057)
0.2 1.5 GO:0055028 cortical microtubule(GO:0055028)
0.1 28.2 GO:0005882 intermediate filament(GO:0005882)
0.1 0.8 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.6 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 1.7 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0031592 centrosomal corona(GO:0031592)
0.1 0.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.4 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 1.1 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 8.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 4.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 1.9 GO:0043034 costamere(GO:0043034)
0.0 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 3.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 3.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.6 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 17.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.7 2.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.6 4.4 GO:1990254 keratin filament binding(GO:1990254)
0.6 2.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 1.5 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.4 1.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3 2.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.3 1.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 0.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 0.7 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 1.0 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.2 2.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 2.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 1.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 3.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 2.2 GO:0045159 myosin II binding(GO:0045159)
0.1 1.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 7.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 2.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 6.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 1.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 3.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 4.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.2 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.1 0.2 GO:0030395 lactose binding(GO:0030395)
0.1 1.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 2.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.4 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 2.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.4 GO:0052846 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.8 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.5 GO:0010181 FMN binding(GO:0010181)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 2.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 4.7 GO:0043621 protein self-association(GO:0043621)
0.1 2.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502) all-trans retinal binding(GO:0005503)
0.0 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 4.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 2.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 1.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 6.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 7.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 1.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0008266 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 1.9 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.8 GO:0031491 protein phosphatase inhibitor activity(GO:0004864) nucleosome binding(GO:0031491)
0.0 0.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 22.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 10.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 3.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.8 PID ATM PATHWAY ATM pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.2 PID MYC PATHWAY C-MYC pathway
0.0 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 2.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 3.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 1.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 2.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.6 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 4.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production