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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFATC2_NFATC3

Z-value: 0.76

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Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
NFATC2
ENSG00000101096.15 nuclear factor of activated T cells 2
NFATC3
ENSG00000072736.14 nuclear factor of activated T cells 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC2hg19_v2_chr20_-_50159198_50159299-0.426.6e-02Click!
NFATC3hg19_v2_chr16_+_68119764_681198680.389.8e-02Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_209602771 4.14 ENST00000440276.1
MIR205HG
MIR205 host gene (non-protein coding)
chr1_-_153538011 3.75 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr12_-_50616122 3.25 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr1_+_209602609 3.21 ENST00000458250.1
MIR205HG
MIR205 host gene (non-protein coding)
chr1_+_46640750 3.01 ENST00000372003.1
TSPAN1
tetraspanin 1
chr18_+_29027696 2.93 ENST00000257189.4
DSG3
desmoglein 3
chr12_-_50616382 2.48 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr7_-_41742697 2.22 ENST00000242208.4
INHBA
inhibin, beta A
chr16_-_28192360 2.19 ENST00000570033.1
XPO6
exportin 6
chr17_-_39093672 2.10 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr3_+_99357319 1.83 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1
collagen, type VIII, alpha 1
chr15_+_93443419 1.76 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr17_+_74372662 1.76 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr3_-_112360116 1.75 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr15_+_43885252 1.75 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr8_+_102504979 1.74 ENST00000395927.1
GRHL2
grainyhead-like 2 (Drosophila)
chr5_-_78808617 1.71 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr14_+_24837226 1.67 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr15_+_43985084 1.66 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr11_+_34654011 1.65 ENST00000531794.1
EHF
ets homologous factor
chr14_+_65170820 1.59 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr17_+_44701402 1.56 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr6_+_106959718 1.56 ENST00000369066.3
AIM1
absent in melanoma 1
chr1_+_24975417 1.53 ENST00000537199.1
SRRM1
serine/arginine repetitive matrix 1
chr11_-_119187826 1.49 ENST00000264036.4
MCAM
melanoma cell adhesion molecule
chr4_-_41216492 1.49 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr11_+_101983176 1.44 ENST00000524575.1
YAP1
Yes-associated protein 1
chr4_+_26322409 1.37 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr6_+_144665237 1.35 ENST00000421035.2
UTRN
utrophin
chr1_-_156675564 1.31 ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr1_-_156675535 1.31 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr16_+_55600580 1.30 ENST00000457326.2
CAPNS2
calpain, small subunit 2
chr11_-_123065989 1.29 ENST00000448775.2
CLMP
CXADR-like membrane protein
chr5_-_124081008 1.29 ENST00000306315.5
ZNF608
zinc finger protein 608
chr3_+_152017924 1.29 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chr4_+_100737954 1.26 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr1_-_207206092 1.26 ENST00000359470.5
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr2_-_163099885 1.22 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr5_+_148960931 1.20 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr2_-_216003127 1.19 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_156675368 1.17 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr2_-_163100045 1.14 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr17_+_36584662 1.14 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr11_+_34663913 1.13 ENST00000532302.1
EHF
ets homologous factor
chr3_-_18480260 1.11 ENST00000454909.2
SATB1
SATB homeobox 1
chr19_+_13134772 1.08 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr6_+_150464155 1.07 ENST00000361131.4
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr14_-_23623577 1.03 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr3_-_71353892 1.03 ENST00000484350.1
FOXP1
forkhead box P1
chr2_-_113594279 1.02 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr3_-_56809534 0.98 ENST00000497267.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr5_+_173316341 0.97 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr11_+_34664014 0.95 ENST00000527935.1
EHF
ets homologous factor
chr6_+_15246501 0.94 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr5_+_49962772 0.92 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr3_+_111578131 0.91 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr13_-_99667960 0.90 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr18_+_55888767 0.89 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr20_+_44637526 0.89 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr6_+_138188378 0.88 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr7_-_20256965 0.86 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr5_+_49963239 0.85 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr14_+_72052983 0.84 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr8_+_128748466 0.84 ENST00000524013.1
ENST00000520751.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr12_-_6484715 0.83 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr6_+_106534192 0.83 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr1_+_150254936 0.83 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr6_+_158733692 0.83 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chrX_+_22056165 0.82 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr4_-_41216473 0.82 ENST00000513140.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr3_+_111578027 0.80 ENST00000431670.2
ENST00000412622.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chrX_+_56259316 0.79 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr14_+_90864504 0.79 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr17_+_7341586 0.78 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr3_-_167813132 0.77 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr4_-_100356291 0.77 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_209941942 0.77 ENST00000487271.1
ENST00000477431.1
TRAF3IP3
TRAF3 interacting protein 3
chr11_-_57089774 0.75 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr3_-_71632894 0.74 ENST00000493089.1
FOXP1
forkhead box P1
chr6_-_112081113 0.74 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr5_+_150591678 0.73 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr4_-_140477353 0.73 ENST00000406354.1
ENST00000506866.2
SETD7
SET domain containing (lysine methyltransferase) 7
chr17_+_7387677 0.73 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr1_+_38022513 0.73 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr7_+_44663908 0.72 ENST00000543843.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr1_+_44401479 0.71 ENST00000438616.3
ARTN
artemin
chr1_-_161337662 0.71 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr14_+_65171099 0.71 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_-_87770416 0.71 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr6_-_47010061 0.70 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr11_+_131240373 0.70 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chr13_-_86373536 0.69 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr9_+_124062071 0.69 ENST00000373818.4
GSN
gelsolin
chr14_+_65171315 0.69 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_+_26322185 0.67 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_8892464 0.67 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr3_+_171844762 0.67 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr1_+_159931002 0.66 ENST00000443364.1
ENST00000423943.1
RP11-48O20.4
long intergenic non-protein coding RNA 1133
chr14_-_61748550 0.66 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr9_+_124329336 0.66 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr1_+_86046433 0.66 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr7_+_55177416 0.65 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr6_+_116691001 0.65 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr12_-_49582837 0.64 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr7_+_134551583 0.63 ENST00000435928.1
CALD1
caldesmon 1
chrX_+_105936982 0.63 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr15_-_42749711 0.63 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106
zinc finger protein 106
chr18_+_61442629 0.63 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chrX_+_48367338 0.63 ENST00000359882.4
ENST00000537758.1
ENST00000367574.4
ENST00000355961.4
ENST00000489940.1
ENST00000361988.3
PORCN
porcupine homolog (Drosophila)
chr6_-_47009996 0.62 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr3_-_141747950 0.62 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr12_+_27396901 0.62 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr1_+_38022572 0.62 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr20_-_10654639 0.62 ENST00000254958.5
JAG1
jagged 1
chr11_+_128563652 0.61 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr10_+_47746929 0.61 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr4_-_153274078 0.60 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr4_+_69313145 0.60 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr11_+_33563821 0.60 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr6_+_43739697 0.59 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr12_-_57037284 0.59 ENST00000551570.1
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr12_-_118490403 0.59 ENST00000535496.1
WSB2
WD repeat and SOCS box containing 2
chr5_-_124080203 0.59 ENST00000504926.1
ZNF608
zinc finger protein 608
chrX_-_41782592 0.58 ENST00000378158.1
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr20_+_12989596 0.58 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr7_-_104909435 0.58 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr1_-_151319318 0.58 ENST00000436271.1
ENST00000450506.1
ENST00000422595.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr10_-_29923893 0.57 ENST00000355867.4
SVIL
supervillin
chr1_-_183559693 0.57 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr11_+_131240593 0.57 ENST00000539799.1
NTM
neurotrimin
chr5_+_138210919 0.57 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr14_+_32546145 0.57 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr12_+_51318513 0.57 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr15_+_96869165 0.57 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr16_+_57679859 0.56 ENST00000569494.1
ENST00000566169.1
GPR56
G protein-coupled receptor 56
chr8_+_94929969 0.56 ENST00000517764.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_68698197 0.56 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr2_-_230787879 0.56 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chrX_+_100663243 0.56 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr15_-_34629922 0.56 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr10_+_111967345 0.55 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr12_+_96588368 0.55 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr8_-_13134246 0.55 ENST00000503161.2
DLC1
deleted in liver cancer 1
chr11_-_57089671 0.55 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr21_-_35899113 0.55 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr1_-_160990886 0.55 ENST00000537746.1
F11R
F11 receptor
chr1_+_24646263 0.55 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr6_-_56716686 0.54 ENST00000520645.1
DST
dystonin
chr11_+_13299186 0.54 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chrX_+_102585124 0.54 ENST00000332431.4
ENST00000372666.1
TCEAL7
transcription elongation factor A (SII)-like 7
chr11_+_86502085 0.54 ENST00000527521.1
PRSS23
protease, serine, 23
chr1_-_115053781 0.54 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr9_-_13165457 0.53 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr11_+_19799327 0.53 ENST00000540292.1
NAV2
neuron navigator 2
chr8_-_13134045 0.52 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr14_-_36988882 0.52 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr3_-_56809685 0.52 ENST00000413728.2
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr1_+_24646002 0.52 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_61547405 0.51 ENST00000371189.4
NFIA
nuclear factor I/A
chr3_-_25706368 0.51 ENST00000424225.1
TOP2B
topoisomerase (DNA) II beta 180kDa
chr4_-_143226979 0.51 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr20_-_57089934 0.50 ENST00000439429.1
ENST00000371149.3
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr1_+_174846570 0.50 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr6_-_75912508 0.50 ENST00000416123.2
COL12A1
collagen, type XII, alpha 1
chr3_+_127770455 0.50 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr20_-_36156125 0.50 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr2_+_191334212 0.49 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr5_+_96211643 0.49 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr1_+_26605618 0.49 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr12_+_112563335 0.49 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr15_+_43985725 0.48 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr3_-_111852061 0.48 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr11_+_58938903 0.48 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr11_+_123986069 0.48 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr10_-_105615164 0.48 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr8_+_55466915 0.48 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr18_-_47376197 0.47 ENST00000592688.1
MYO5B
myosin VB
chr11_-_46113756 0.47 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr8_+_38854368 0.47 ENST00000466936.1
ADAM9
ADAM metallopeptidase domain 9
chr16_+_57679945 0.47 ENST00000568157.1
GPR56
G protein-coupled receptor 56
chr3_+_9944492 0.47 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
IL17RE
interleukin 17 receptor E
chr13_+_97928395 0.47 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr15_-_41694640 0.46 ENST00000558719.1
ENST00000260361.4
ENST00000560978.1
NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr5_-_124082279 0.46 ENST00000513986.1
ZNF608
zinc finger protein 608
chrX_-_30993201 0.46 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr14_-_54955376 0.46 ENST00000553333.1
GMFB
glia maturation factor, beta
chr5_-_42811986 0.46 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr1_+_151512775 0.46 ENST00000368849.3
ENST00000392712.3
ENST00000353024.3
ENST00000368848.2
ENST00000538902.1
TUFT1
tuftelin 1
chr11_+_35211429 0.46 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr6_-_11779403 0.46 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr7_-_107204337 0.46 ENST00000605888.1
ENST00000347053.3
COG5
component of oligomeric golgi complex 5
chr2_-_134326009 0.45 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr10_-_27149851 0.45 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
ABI1
abl-interactor 1
chr14_+_62164340 0.45 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chrX_+_105937068 0.45 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr8_-_11710979 0.45 ENST00000415599.2
CTSB
cathepsin B
chr8_+_42873548 0.44 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr12_-_76425368 0.44 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr1_+_24645915 0.44 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr9_+_115913222 0.44 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.7 2.2 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.6 1.3 GO:0048565 digestive tract development(GO:0048565)
0.6 1.8 GO:0046521 sphingoid catabolic process(GO:0046521)
0.6 1.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 1.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 1.0 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.3 2.4 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 1.2 GO:0035627 ceramide transport(GO:0035627)
0.3 1.8 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 1.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 1.7 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.7 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 1.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.7 GO:0001172 transcription, RNA-templated(GO:0001172)
0.2 0.7 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 3.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 0.8 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 0.6 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.7 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 1.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.2 0.9 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.6 GO:0035494 SNARE complex disassembly(GO:0035494)
0.2 2.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.3 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.2 1.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.9 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.4 GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.1 0.4 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 0.7 GO:0003409 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.7 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 0.6 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.4 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.1 0.7 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.7 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 1.5 GO:0070487 monocyte aggregation(GO:0070487)
0.1 0.7 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 2.1 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 1.5 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.0 GO:0033590 response to cobalamin(GO:0033590)
0.1 1.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1 0.6 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.5 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.8 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1 2.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.4 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 0.3 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.4 GO:0060242 contact inhibition(GO:0060242)
0.1 0.5 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.2 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.5 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 1.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 2.5 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.4 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 1.4 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 5.4 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 0.3 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.2 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 0.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.1 GO:0016241 regulation of macroautophagy(GO:0016241)
0.1 0.5 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.3 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 1.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.6 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.8 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.2 GO:0072209 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.5 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0032439 endosome localization(GO:0032439)
0.1 0.6 GO:0060591 chondroblast differentiation(GO:0060591)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.5 GO:0060004 reflex(GO:0060004)
0.1 0.6 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.6 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.4 GO:0019075 virus maturation(GO:0019075)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.4 GO:1900044 regulation of protein K63-linked ubiquitination(GO:1900044)
0.1 0.5 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.3 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.3 GO:1990169 detoxification of copper ion(GO:0010273) cellular response to erythropoietin(GO:0036018) stress response to copper ion(GO:1990169)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.5 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.5 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.4 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.2 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 1.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.6 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.5 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.0 0.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.2 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.4 GO:0060174 limb bud formation(GO:0060174)
0.0 1.0 GO:0015695 organic cation transport(GO:0015695)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.9 GO:0060074 synapse maturation(GO:0060074)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 4.3 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.6 GO:0046697 decidualization(GO:0046697)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619) female courtship behavior(GO:0008050)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.3 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0001781 neutrophil apoptotic process(GO:0001781)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 1.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 1.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.6 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.4 GO:0009642 response to light intensity(GO:0009642)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.6 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0 0.3 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 1.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.0 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0061157 mRNA destabilization(GO:0061157)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 2.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 0.7 GO:1990032 parallel fiber(GO:1990032)
0.2 0.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.2 0.7 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 1.8 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2 1.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 0.5 GO:0005595 collagen type XII trimer(GO:0005595)
0.2 0.6 GO:0031592 centrosomal corona(GO:0031592)
0.1 2.2 GO:0045180 basal cortex(GO:0045180)
0.1 2.6 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 3.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.4 GO:0019867 outer membrane(GO:0019867)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.3 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 3.3 GO:0030057 desmosome(GO:0030057)
0.1 1.4 GO:0070938 contractile ring(GO:0070938)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.5 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.9 GO:0012505 endomembrane system(GO:0012505)
0.1 6.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.5 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 1.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.0 1.0 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 1.9 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 1.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.8 GO:0034706 sodium channel complex(GO:0034706)
0.0 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.1 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 3.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.4 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:1990752 microtubule end(GO:1990752)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 1.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 1.2 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.3 1.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 1.8 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.7 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.2 2.1 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.6 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.2 0.7 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 3.9 GO:0019841 retinol binding(GO:0019841)
0.2 0.5 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 1.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.8 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 2.4 GO:0000150 recombinase activity(GO:0000150)
0.1 0.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 2.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.5 GO:0045159 myosin II binding(GO:0045159)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.5 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 2.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 5.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 2.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.5 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.2 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 1.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 1.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.1 1.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 2.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.5 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.3 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 1.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.2 GO:0017166 vinculin binding(GO:0017166)
0.0 1.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.6 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 1.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 1.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 5.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.7 GO:0043621 protein self-association(GO:0043621)
0.0 2.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0047391 phosphodiesterase I activity(GO:0004528) alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.0 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0032451 cobalamin binding(GO:0031419) demethylase activity(GO:0032451)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 2.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 4.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.8 PID MYC PATHWAY C-MYC pathway
0.0 1.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.5 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 2.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 1.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2