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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFATC4

Z-value: 0.70

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Transcription factors associated with NFATC4

Gene Symbol Gene ID Gene Info
NFATC4
ENSG00000100968.9 nuclear factor of activated T cells 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC4hg19_v2_chr14_+_24837226_248375470.732.8e-04Click!

Activity profile of NFATC4 motif

Sorted Z-values of NFATC4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_49833978 2.19 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr17_-_39093672 1.98 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr11_-_87908600 1.91 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr1_+_158979792 1.76 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr1_+_24646263 1.69 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr12_-_28125638 1.60 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr1_+_24975417 1.57 ENST00000537199.1
SRRM1
serine/arginine repetitive matrix 1
chr12_+_13349650 1.56 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr4_+_26322409 1.51 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr21_-_28215332 1.42 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr6_-_47010061 1.38 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr6_+_144665237 1.38 ENST00000421035.2
UTRN
utrophin
chr6_-_47009996 1.37 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr10_-_10836865 1.34 ENST00000446372.2
SFTA1P
surfactant associated 1, pseudogene
chr3_+_156393349 1.33 ENST00000473702.1
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr15_+_43885252 1.30 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr11_-_46113756 1.29 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr11_+_123986069 1.28 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr14_-_61748550 1.26 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr1_+_36789335 1.24 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr15_+_43985084 1.24 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr3_+_171844762 1.22 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr14_+_85996507 1.22 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_+_24645807 1.19 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr6_-_56716686 1.17 ENST00000520645.1
DST
dystonin
chr17_+_44701402 1.16 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr3_-_18480260 1.16 ENST00000454909.2
SATB1
SATB homeobox 1
chr11_+_58938903 1.13 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chrX_+_115567767 1.13 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr1_+_158979686 1.12 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr14_+_85996471 1.12 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_-_8892464 1.12 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr11_+_66824303 1.11 ENST00000533360.1
RHOD
ras homolog family member D
chr1_+_158979680 1.10 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr1_+_24646002 1.09 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr5_-_112630598 1.08 ENST00000302475.4
MCC
mutated in colorectal cancers
chr1_-_221915418 1.07 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr11_+_101983176 1.07 ENST00000524575.1
YAP1
Yes-associated protein 1
chr17_+_74372662 1.07 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr1_+_24645865 1.07 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr17_+_36584662 1.06 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr1_-_1763721 1.05 ENST00000437146.1
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr1_+_151512775 1.04 ENST00000368849.3
ENST00000392712.3
ENST00000353024.3
ENST00000368848.2
ENST00000538902.1
TUFT1
tuftelin 1
chr11_-_96076334 1.04 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr1_-_161337662 1.03 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chrX_-_43741594 1.03 ENST00000536181.1
ENST00000378069.4
MAOB
monoamine oxidase B
chr11_-_65429891 1.02 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr17_+_48610074 1.01 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr7_+_18535893 1.01 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr4_-_41216492 0.98 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr5_-_42811986 0.98 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr12_+_13349711 0.97 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr3_+_118905564 0.96 ENST00000460625.1
UPK1B
uroplakin 1B
chr12_+_51318513 0.95 ENST00000332160.4
METTL7A
methyltransferase like 7A
chrX_-_73051037 0.95 ENST00000445814.1
XIST
X inactive specific transcript (non-protein coding)
chr20_+_12989596 0.94 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr5_-_124081008 0.93 ENST00000306315.5
ZNF608
zinc finger protein 608
chr2_+_191208656 0.93 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr11_+_66824276 0.93 ENST00000308831.2
RHOD
ras homolog family member D
chr1_-_152297679 0.92 ENST00000368799.1
FLG
filaggrin
chr19_+_11200038 0.91 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr17_-_76732928 0.90 ENST00000589768.1
CYTH1
cytohesin 1
chr4_+_26322185 0.90 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr7_-_92747269 0.90 ENST00000446617.1
ENST00000379958.2
SAMD9
sterile alpha motif domain containing 9
chr1_+_24645915 0.90 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr7_+_18536090 0.89 ENST00000441986.1
HDAC9
histone deacetylase 9
chr11_-_12030629 0.88 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr4_-_80994619 0.88 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr3_-_195997410 0.88 ENST00000419333.1
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
chr2_+_191208791 0.86 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr3_-_69370095 0.86 ENST00000473029.1
FRMD4B
FERM domain containing 4B
chr3_-_197024394 0.86 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chrX_-_30877837 0.85 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr6_-_167276033 0.84 ENST00000503859.1
ENST00000506565.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_+_32546145 0.84 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr5_-_42812143 0.82 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr8_-_57123815 0.82 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr1_+_111682058 0.82 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr18_+_55888767 0.81 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr12_+_27396901 0.81 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr9_+_706842 0.80 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr11_-_33757950 0.80 ENST00000533403.1
ENST00000528700.1
ENST00000527577.1
ENST00000395850.3
ENST00000351554.3
CD59
CD59 molecule, complement regulatory protein
chr9_+_34989638 0.79 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr7_-_105319536 0.78 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr2_+_191208601 0.78 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chrX_+_22056165 0.78 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr17_+_48610042 0.78 ENST00000503246.1
EPN3
epsin 3
chrX_-_15619076 0.77 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr12_+_14518598 0.77 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP
activating transcription factor 7 interacting protein
chr1_-_184723701 0.77 ENST00000367512.3
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr14_+_65170820 0.77 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_-_155881156 0.76 ENST00000539040.1
ENST00000368323.3
RIT1
Ras-like without CAAX 1
chr5_+_72251857 0.75 ENST00000507345.2
ENST00000512348.1
ENST00000287761.6
FCHO2
FCH domain only 2
chr2_-_122247879 0.74 ENST00000545861.1
CLASP1
cytoplasmic linker associated protein 1
chrX_-_84634708 0.74 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr1_-_68698197 0.73 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr19_+_52996047 0.73 ENST00000601120.1
ZNF578
zinc finger protein 578
chr8_+_94929969 0.72 ENST00000517764.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_+_31885963 0.71 ENST00000373709.3
SERINC2
serine incorporator 2
chr7_+_18535346 0.71 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr3_-_93747425 0.70 ENST00000315099.2
STX19
syntaxin 19
chr20_-_45985464 0.70 ENST00000458360.2
ENST00000262975.4
ZMYND8
zinc finger, MYND-type containing 8
chr20_+_35201993 0.70 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr14_+_75988768 0.69 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr6_-_167275991 0.69 ENST00000510118.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_-_65430251 0.69 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr19_-_53606604 0.69 ENST00000599056.1
ENST00000599247.1
ENST00000355147.5
ENST00000429604.1
ENST00000418871.1
ENST00000599637.1
ZNF160
zinc finger protein 160
chr1_-_151299842 0.68 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr5_+_145317356 0.68 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr13_-_30169807 0.68 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_+_63953415 0.67 ENST00000484332.1
ATXN7
ataxin 7
chr2_+_98703595 0.66 ENST00000435344.1
VWA3B
von Willebrand factor A domain containing 3B
chr11_-_85779786 0.66 ENST00000356360.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chr7_-_107204337 0.66 ENST00000605888.1
ENST00000347053.3
COG5
component of oligomeric golgi complex 5
chr5_+_82767284 0.65 ENST00000265077.3
VCAN
versican
chr20_-_45985414 0.65 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
ZMYND8
zinc finger, MYND-type containing 8
chr14_-_24711470 0.65 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr4_+_74301880 0.64 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr1_+_65613513 0.64 ENST00000395334.2
AK4
adenylate kinase 4
chr1_+_117963209 0.64 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr20_-_45985172 0.63 ENST00000536340.1
ZMYND8
zinc finger, MYND-type containing 8
chr15_-_77712429 0.62 ENST00000564328.1
ENST00000558305.1
PEAK1
pseudopodium-enriched atypical kinase 1
chr8_+_28747884 0.61 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
HMBOX1
homeobox containing 1
chr18_+_52385068 0.61 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr7_+_18535854 0.60 ENST00000401921.1
HDAC9
histone deacetylase 9
chr5_+_15500280 0.60 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr4_-_166034029 0.60 ENST00000306480.6
TMEM192
transmembrane protein 192
chr19_+_35645817 0.59 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr4_-_41216473 0.59 ENST00000513140.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr3_+_177159695 0.59 ENST00000442937.1
LINC00578
long intergenic non-protein coding RNA 578
chr10_+_121578211 0.59 ENST00000369080.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr1_-_205744205 0.58 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr4_+_26323764 0.58 ENST00000514730.1
ENST00000507574.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_+_65613340 0.58 ENST00000546702.1
AK4
adenylate kinase 4
chr1_-_145470383 0.57 ENST00000369314.1
ENST00000369313.3
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr10_+_129785536 0.56 ENST00000419012.2
PTPRE
protein tyrosine phosphatase, receptor type, E
chr19_+_35645618 0.56 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr5_-_43412418 0.56 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chrX_+_100663243 0.56 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr16_+_67062996 0.56 ENST00000561924.2
CBFB
core-binding factor, beta subunit
chr14_+_85994943 0.56 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr20_+_12989822 0.56 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr3_-_18480173 0.56 ENST00000414509.1
SATB1
SATB homeobox 1
chr7_+_18535321 0.55 ENST00000413380.1
ENST00000430454.1
HDAC9
histone deacetylase 9
chr6_-_35888905 0.55 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr1_-_151826173 0.54 ENST00000368817.5
THEM5
thioesterase superfamily member 5
chr22_-_36236623 0.54 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_-_74551096 0.54 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_+_40420802 0.54 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
MFSD2A
major facilitator superfamily domain containing 2A
chr11_+_120255997 0.52 ENST00000532993.1
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr21_+_38792602 0.51 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr6_+_106534192 0.51 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr5_+_43603229 0.51 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr12_-_89918982 0.51 ENST00000549504.1
POC1B
POC1 centriolar protein B
chr8_-_22089845 0.51 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr12_-_47219733 0.50 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4
solute carrier family 38, member 4
chr6_+_90272027 0.50 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr2_+_98703695 0.50 ENST00000451075.2
VWA3B
von Willebrand factor A domain containing 3B
chr22_-_36220420 0.50 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_50649302 0.50 ENST00000446044.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr6_+_158733692 0.50 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr19_-_39390212 0.49 ENST00000437828.1
SIRT2
sirtuin 2
chr11_-_88070896 0.49 ENST00000529974.1
ENST00000527018.1
CTSC
cathepsin C
chr4_-_153303658 0.48 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_+_28995258 0.48 ENST00000361872.4
ENST00000294409.2
GMEB1
glucocorticoid modulatory element binding protein 1
chr1_+_174846570 0.48 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr15_+_65914347 0.48 ENST00000544319.2
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr4_+_39046615 0.48 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr7_+_132937820 0.47 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr17_-_58499766 0.47 ENST00000588898.1
USP32
ubiquitin specific peptidase 32
chr5_+_43602750 0.47 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr16_-_18937072 0.47 ENST00000569122.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr5_-_133510456 0.47 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr1_-_205744574 0.47 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr6_+_87865262 0.47 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr1_+_99127225 0.46 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr19_-_39390350 0.46 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr3_+_177534653 0.46 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chr5_+_72112470 0.45 ENST00000447967.2
ENST00000523768.1
TNPO1
transportin 1
chr6_-_112081113 0.45 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr12_-_10007448 0.44 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr1_+_99127265 0.44 ENST00000306121.3
SNX7
sorting nexin 7
chr1_+_100503643 0.44 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr12_+_64798826 0.44 ENST00000540203.1
XPOT
exportin, tRNA
chr5_+_131409476 0.44 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr17_-_39942322 0.44 ENST00000449889.1
ENST00000465293.1
JUP
junction plakoglobin
chr2_+_98703643 0.44 ENST00000477737.1
VWA3B
von Willebrand factor A domain containing 3B
chr1_+_78470530 0.43 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr20_-_14318248 0.43 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr11_+_86502085 0.43 ENST00000527521.1
PRSS23
protease, serine, 23
chr19_-_36909528 0.43 ENST00000392161.3
ENST00000392171.1
ZFP82
ZFP82 zinc finger protein
chr1_+_65613217 0.42 ENST00000545314.1
AK4
adenylate kinase 4
chr6_-_134495992 0.42 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr8_-_18541603 0.41 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_147245484 0.41 ENST00000271348.2
GJA5
gap junction protein, alpha 5, 40kDa
chr14_+_65171315 0.41 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr7_+_18535786 0.40 ENST00000406072.1
HDAC9
histone deacetylase 9
chr1_-_147245445 0.40 ENST00000430508.1
GJA5
gap junction protein, alpha 5, 40kDa
chr19_-_39390440 0.40 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr1_+_79115503 0.40 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6 1.7 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.5 1.4 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.4 2.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.4 1.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.4 3.0 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4 1.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 1.9 GO:1903232 melanosome assembly(GO:1903232)
0.3 0.8 GO:0098906 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.3 1.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 0.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 5.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 0.9 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.2 2.0 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 4.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 0.8 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.2 0.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 1.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 1.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 0.6 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 0.8 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.4 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 1.0 GO:0006740 NADPH regeneration(GO:0006740)
0.1 1.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.8 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 1.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 2.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.7 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.9 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 1.1 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.5 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.8 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 1.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.7 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 1.5 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.3 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 1.4 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.9 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 2.5 GO:0032060 bleb assembly(GO:0032060)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.3 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 0.6 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.6 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 1.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.2 GO:0006600 creatine metabolic process(GO:0006600)
0.1 1.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.3 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.5 GO:0046449 creatinine metabolic process(GO:0046449)
0.1 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.3 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 4.0 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.6 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 0.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 1.7 GO:0060004 reflex(GO:0060004)
0.1 1.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.2 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.4 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 1.6 GO:0002076 osteoblast development(GO:0002076)
0.0 0.3 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.8 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 1.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 1.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.3 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 1.2 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:1904647 response to rotenone(GO:1904647)
0.0 1.0 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.4 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.5 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 1.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 2.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.7 GO:0061436 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 2.7 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.7 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 1.2 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 1.9 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.5 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.7 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.4 1.9 GO:0031905 early endosome lumen(GO:0031905)
0.3 0.9 GO:0036457 keratohyalin granule(GO:0036457)
0.3 0.9 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.3 3.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 1.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 0.6 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.2 1.2 GO:0031673 H zone(GO:0031673)
0.2 0.7 GO:0031592 centrosomal corona(GO:0031592)
0.1 2.2 GO:0043219 lateral loop(GO:0043219)
0.1 1.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.6 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 1.4 GO:0070938 contractile ring(GO:0070938)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.9 GO:0042587 glycogen granule(GO:0042587)
0.1 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 2.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 5.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 3.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 3.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 2.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.5 1.9 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.5 1.4 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.4 1.8 GO:1990175 EH domain binding(GO:1990175)
0.3 1.0 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 1.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 0.8 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.2 1.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 2.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.0 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 0.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2 1.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 2.7 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 1.2 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 4.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.9 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.8 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.1 GO:0019956 chemokine binding(GO:0019956)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 2.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.6 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.4 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.8 GO:0031404 chloride ion binding(GO:0031404)
0.0 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 3.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 1.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 3.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 3.6 GO:0001047 core promoter binding(GO:0001047)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 3.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 3.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.4 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 4.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling