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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFE2L1

Z-value: 1.68

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Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
ENSG00000082641.11 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v2_chr17_+_46125707_461257460.913.0e-08Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52887034 19.88 ENST00000330722.6
keratin 6A
chr11_+_117947782 11.74 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
transmembrane protease, serine 4
chr2_-_161056762 8.48 ENST00000428609.2
ENST00000409967.2
integrin, beta 6
chr12_-_15104040 8.26 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_161056802 8.13 ENST00000283249.2
ENST00000409872.1
integrin, beta 6
chr2_-_113594279 7.89 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr11_+_117947724 7.64 ENST00000534111.1
transmembrane protease, serine 4
chr12_-_15103621 6.88 ENST00000536592.1
Rho GDP dissociation inhibitor (GDI) beta
chr11_-_119999539 6.76 ENST00000541857.1
tripartite motif containing 29
chr11_-_119999611 6.70 ENST00000529044.1
tripartite motif containing 29
chr11_+_35211511 6.23 ENST00000524922.1
CD44 molecule (Indian blood group)
chr12_-_123187890 6.00 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr17_-_7165662 5.96 ENST00000571881.2
ENST00000360325.7
claudin 7
chr11_+_35222629 5.52 ENST00000526553.1
CD44 molecule (Indian blood group)
chr19_-_42947121 5.46 ENST00000601181.1
chemokine (C-X-C motif) ligand 17
chr9_-_117853297 5.43 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
tenascin C
chr10_+_5566916 5.40 ENST00000315238.1
calmodulin-like 3
chr1_-_209975494 5.35 ENST00000456314.1
interferon regulatory factor 6
chr2_+_169926047 5.14 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr12_-_123201337 5.00 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr1_+_35220613 4.97 ENST00000338513.1
gap junction protein, beta 5, 31.1kDa
chr2_+_113735575 4.89 ENST00000376489.2
ENST00000259205.4
interleukin 36, gamma
chr6_-_32784687 4.85 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr11_-_125366089 4.41 ENST00000366139.3
ENST00000278919.3
fasciculation and elongation protein zeta 1 (zygin I)
chr6_-_56507586 4.31 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
dystonin
chr6_-_113953705 4.28 ENST00000452675.1
RP11-367G18.1
chr16_+_8814563 4.20 ENST00000425191.2
ENST00000569156.1
4-aminobutyrate aminotransferase
chr22_-_38349552 4.12 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
chromosome 22 open reading frame 23
chr11_-_87908600 4.01 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38, member RAS oncogene family
chr2_+_169923504 3.82 ENST00000357546.2
dehydrogenase/reductase (SDR family) member 9
chr1_+_203651937 3.56 ENST00000341360.2
ATPase, Ca++ transporting, plasma membrane 4
chr1_+_26605618 3.56 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr10_-_123357598 3.47 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
fibroblast growth factor receptor 2
chr11_-_119991589 3.46 ENST00000526881.1
tripartite motif containing 29
chr10_-_123357910 3.43 ENST00000336553.6
ENST00000457416.2
ENST00000360144.3
ENST00000369059.1
ENST00000356226.4
ENST00000351936.6
fibroblast growth factor receptor 2
chr6_+_86195088 3.31 ENST00000437581.1
5'-nucleotidase, ecto (CD73)
chr11_+_123986069 3.24 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
von Willebrand factor A domain containing 5A
chr8_+_24151553 3.10 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr2_+_169923577 3.07 ENST00000432060.2
dehydrogenase/reductase (SDR family) member 9
chr1_-_153113927 3.07 ENST00000368752.4
small proline-rich protein 2B
chr1_-_183538319 3.07 ENST00000420553.1
ENST00000419402.1
neutrophil cytosolic factor 2
chr19_-_51530916 2.95 ENST00000594768.1
kallikrein-related peptidase 11
chr5_-_160279207 2.90 ENST00000327245.5
ATPase, class V, type 10B
chr1_+_112939121 2.88 ENST00000441739.1
CTTNBP2 N-terminal like
chr5_-_112630598 2.83 ENST00000302475.4
mutated in colorectal cancers
chr12_-_123380610 2.82 ENST00000535765.1
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr5_+_36608422 2.81 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_41130914 2.80 ENST00000373113.3
ENST00000338469.3
triggering receptor expressed on myeloid cells 2
chr2_-_46385 2.80 ENST00000327669.4
family with sequence similarity 110, member C
chr1_-_39395165 2.79 ENST00000372985.3
rhomboid, veinlet-like 2 (Drosophila)
chr7_-_41742697 2.76 ENST00000242208.4
inhibin, beta A
chr19_-_36019123 2.62 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr6_+_163837347 2.61 ENST00000544436.1
QKI, KH domain containing, RNA binding
chr16_+_21623958 2.61 ENST00000568826.1
methyltransferase like 9
chr3_+_45730829 2.59 ENST00000438671.1
SAC1 suppressor of actin mutations 1-like (yeast)
chrX_+_99899180 2.58 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr15_+_45406519 2.58 ENST00000323030.5
dual oxidase maturation factor 2
chr1_+_112938803 2.55 ENST00000271277.6
CTTNBP2 N-terminal like
chr18_-_68004529 2.54 ENST00000578633.1
RP11-484N16.1
chr11_-_46113756 2.47 ENST00000531959.1
PHD finger protein 21A
chr11_+_35198243 2.45 ENST00000528455.1
CD44 molecule (Indian blood group)
chr4_+_169013666 2.44 ENST00000359299.3
annexin A10
chr1_+_43735646 2.34 ENST00000439858.1
transmembrane protein 125
chr17_+_7461580 2.33 ENST00000483039.1
ENST00000396542.1
tumor necrosis factor (ligand) superfamily, member 13
chr6_+_143381979 2.32 ENST00000367598.5
ENST00000447498.1
ENST00000357847.4
ENST00000344492.5
ENST00000367596.1
ENST00000494282.2
ENST00000275235.4
androgen-induced 1
chr18_+_55888767 2.30 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_+_35211429 2.29 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44 molecule (Indian blood group)
chr14_-_36988882 2.29 ENST00000498187.2
NK2 homeobox 1
chr15_-_45406385 2.29 ENST00000389039.6
dual oxidase 2
chr2_+_201242715 2.18 ENST00000421573.1
spermatogenesis associated, serine-rich 2-like
chr18_+_11752783 2.12 ENST00000585642.1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr12_-_120663792 2.11 ENST00000546532.1
ENST00000548912.1
paxillin
chr1_-_113258090 2.09 ENST00000309276.6
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chrX_+_9754461 2.05 ENST00000380913.3
shroom family member 2
chr4_+_71384257 2.05 ENST00000339336.4
amelotin
chr8_+_22853345 2.04 ENST00000522948.1
Rho-related BTB domain containing 2
chr8_+_24151620 1.99 ENST00000437154.2
ADAM metallopeptidase domain 28
chr10_-_115904361 1.99 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chr19_+_35645618 1.98 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr1_+_29241027 1.96 ENST00000373797.1
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_+_82165350 1.95 ENST00000359929.3
latrophilin 2
chr2_-_230787879 1.93 ENST00000435716.1
thyroid hormone receptor interactor 12
chr2_-_70781087 1.93 ENST00000394241.3
ENST00000295400.6
transforming growth factor, alpha
chr17_+_42081914 1.92 ENST00000293404.3
ENST00000589767.1
N-acetylglutamate synthase
chrX_-_30993201 1.92 ENST00000288422.2
ENST00000378932.2
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr10_+_127661942 1.91 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr18_+_72166564 1.90 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr4_+_71384300 1.90 ENST00000504451.1
amelotin
chr6_-_32145861 1.90 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr1_-_214638146 1.90 ENST00000543945.1
protein tyrosine phosphatase, non-receptor type 14
chr11_+_35201826 1.89 ENST00000531873.1
CD44 molecule (Indian blood group)
chr19_-_35992780 1.89 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
dermokine
chr9_+_109694914 1.88 ENST00000542028.1
zinc finger protein 462
chr2_+_234602305 1.86 ENST00000406651.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr10_-_5638048 1.86 ENST00000478294.1
RP13-463N16.6
chr11_-_128894053 1.85 ENST00000392657.3
Rho GTPase activating protein 32
chrX_+_134654540 1.82 ENST00000370752.4
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_-_54813229 1.82 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_+_43735678 1.80 ENST00000432792.2
transmembrane protein 125
chr4_+_144303093 1.80 ENST00000505913.1
GRB2-associated binding protein 1
chr1_+_28586006 1.79 ENST00000253063.3
sestrin 2
chr14_+_52164675 1.76 ENST00000555936.1
FERM domain containing 6
chr15_-_45406348 1.76 ENST00000603300.1
dual oxidase 2
chr8_+_55466915 1.75 ENST00000522711.2
RP11-53M11.3
chr15_-_81616446 1.74 ENST00000302824.6
StAR-related lipid transfer (START) domain containing 5
chr3_-_171489085 1.71 ENST00000418087.1
phospholipase D1, phosphatidylcholine-specific
chr3_-_59035673 1.70 ENST00000491845.1
ENST00000472469.1
ENST00000471288.1
ENST00000295966.7
chromosome 3 open reading frame 67
chr4_+_3344141 1.68 ENST00000306648.7
regulator of G-protein signaling 12
chr10_+_5488564 1.64 ENST00000449083.1
ENST00000380359.3
neuroepithelial cell transforming 1
chr6_-_31619892 1.60 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BCL2-associated athanogene 6
chr4_+_185734773 1.59 ENST00000508020.1
Uncharacterized protein
chr19_-_58485895 1.58 ENST00000314391.3
chromosome 19 open reading frame 18
chr6_+_63921399 1.56 ENST00000356170.3
FK506 binding protein 1C
chr9_-_100684769 1.55 ENST00000455506.1
ENST00000375117.4
chromosome 9 open reading frame 156
chr7_+_6713376 1.52 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
Uncharacterized protein
chr11_-_126138808 1.51 ENST00000332118.6
ENST00000532259.1
signal recognition particle receptor (docking protein)
chr4_+_26324474 1.50 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr11_+_35198118 1.50 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chr16_-_67881588 1.48 ENST00000561593.1
ENST00000565114.1
centromere protein T
chr8_+_104831472 1.48 ENST00000262231.10
ENST00000507740.1
regulating synaptic membrane exocytosis 2
chr11_+_59480899 1.47 ENST00000300150.7
syntaxin 3
chr15_+_94899183 1.47 ENST00000557742.1
multiple C2 domains, transmembrane 2
chr1_+_152758690 1.46 ENST00000368771.1
ENST00000368770.3
late cornified envelope 1E
chr2_+_201242941 1.46 ENST00000449647.1
spermatogenesis associated, serine-rich 2-like
chr6_+_143381594 1.45 ENST00000367601.4
androgen-induced 1
chr21_+_39668831 1.45 ENST00000419868.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_+_72064945 1.45 ENST00000537413.1
signal-induced proliferation-associated 1 like 1
chr5_+_125800836 1.44 ENST00000511134.1
GRAM domain containing 3
chr12_+_112563335 1.43 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr19_+_11200038 1.43 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
low density lipoprotein receptor
chr3_-_56809685 1.40 ENST00000413728.2
Rho guanine nucleotide exchange factor (GEF) 3
chr6_+_30539153 1.40 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ATP-binding cassette, sub-family F (GCN20), member 1
chr15_+_93447675 1.40 ENST00000536619.1
chromodomain helicase DNA binding protein 2
chr13_+_76378357 1.38 ENST00000489941.2
ENST00000525373.1
LIM domain 7
chr6_-_31619697 1.37 ENST00000434444.1
BCL2-associated athanogene 6
chr22_-_39097527 1.36 ENST00000417712.1
Josephin domain containing 1
chr9_+_72002837 1.36 ENST00000377216.3
family with sequence similarity 189, member A2
chr18_+_34124507 1.36 ENST00000591635.1
formin homology 2 domain containing 3
chr16_+_57662138 1.36 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr5_+_65440032 1.36 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr6_+_74405501 1.36 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr17_+_26662679 1.36 ENST00000578158.1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr4_-_119759795 1.35 ENST00000419654.2
SEC24 family member D
chr12_+_40787194 1.34 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr22_+_20861858 1.34 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
mediator complex subunit 15
chr17_+_7461613 1.32 ENST00000438470.1
ENST00000436057.1
tumor necrosis factor (ligand) superfamily, member 13
chr3_-_12587055 1.32 ENST00000564146.3
chromosome 3 open reading frame 83
chr8_+_128747757 1.32 ENST00000517291.1
v-myc avian myelocytomatosis viral oncogene homolog
chr22_-_43040515 1.31 ENST00000361740.4
cytochrome b5 reductase 3
chr6_-_31619742 1.31 ENST00000433828.1
ENST00000456286.1
BCL2-associated athanogene 6
chr11_+_71903169 1.31 ENST00000393676.3
folate receptor 1 (adult)
chr14_-_69262947 1.30 ENST00000557086.1
ZFP36 ring finger protein-like 1
chr12_+_112563303 1.29 ENST00000412615.2
TRAF-type zinc finger domain containing 1
chr1_+_45265897 1.29 ENST00000372201.4
polo-like kinase 3
chr4_+_3388057 1.29 ENST00000538395.1
regulator of G-protein signaling 12
chr8_-_29592736 1.28 ENST00000518623.1
long intergenic non-protein coding RNA 589
chr17_+_28256874 1.26 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr1_+_2066387 1.24 ENST00000497183.1
protein kinase C, zeta
chr22_+_20862321 1.24 ENST00000541476.1
ENST00000438962.1
mediator complex subunit 15
chrM_+_7586 1.23 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr1_+_43613612 1.22 ENST00000335282.4
family with sequence similarity 183, member A
chr2_-_220119280 1.21 ENST00000392088.2
tubulin, alpha 4a
chr10_+_5932174 1.19 ENST00000362091.4
F-box protein, helicase, 18
chr15_-_43559055 1.19 ENST00000220420.5
ENST00000349114.4
transglutaminase 5
chr14_-_24768913 1.17 ENST00000288111.7
dehydrogenase/reductase (SDR family) member 1
chr1_-_156265438 1.17 ENST00000362007.1
chromosome 1 open reading frame 85
chr4_-_87028478 1.16 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr11_+_101983176 1.16 ENST00000524575.1
Yes-associated protein 1
chr2_+_182850551 1.16 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr3_-_143567262 1.16 ENST00000474151.1
ENST00000316549.6
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr19_-_14606900 1.14 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC PDZ domain containing family, member 1
chr6_+_74405804 1.13 ENST00000287097.5
CD109 molecule
chr3_-_47932759 1.12 ENST00000441748.2
ENST00000335271.5
microtubule-associated protein 4
chr3_-_47950745 1.12 ENST00000429422.1
microtubule-associated protein 4
chr1_-_151319654 1.11 ENST00000430227.1
ENST00000412774.1
regulatory factor X, 5 (influences HLA class II expression)
chr21_+_40823753 1.11 ENST00000333634.4
SH3 domain binding glutamic acid-rich protein
chr2_+_182850743 1.10 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_-_95523500 1.10 ENST00000540054.1
family with sequence similarity 76, member B
chr9_-_14180778 1.10 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr5_-_41794663 1.10 ENST00000510634.1
3-oxoacid CoA transferase 1
chr6_-_99873145 1.08 ENST00000369239.5
ENST00000438806.1
PNN-interacting serine/arginine-rich protein
chr3_-_105588231 1.08 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr17_-_8021710 1.08 ENST00000380149.1
ENST00000448843.2
arachidonate lipoxygenase 3
chr8_+_79503458 1.06 ENST00000518467.1
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr10_+_13142075 1.06 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
optineurin
chr15_-_43876702 1.06 ENST00000348806.6
diphosphoinositol pentakisphosphate kinase 1
chr2_+_219110149 1.05 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr10_+_13142225 1.03 ENST00000378747.3
optineurin
chr1_+_43148059 1.03 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr4_+_26165074 1.02 ENST00000512351.1
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_159080806 1.01 ENST00000590648.1
family with sequence similarity 198, member B
chr15_-_43877062 1.01 ENST00000381885.1
ENST00000396923.3
diphosphoinositol pentakisphosphate kinase 1
chr5_-_133706695 1.00 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr4_+_26344754 1.00 ENST00000515573.1
recombination signal binding protein for immunoglobulin kappa J region
chr19_+_11546093 0.99 ENST00000591462.1
protein kinase C substrate 80K-H
chr1_+_100435986 0.99 ENST00000532693.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr14_-_75083313 0.98 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr17_-_40170506 0.98 ENST00000589773.1
ENST00000590348.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr6_+_15249128 0.98 ENST00000397311.3
jumonji, AT rich interactive domain 2
chr19_+_11546153 0.97 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
protein kinase C substrate 80K-H

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 19.9 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
2.3 27.8 GO:0070487 monocyte aggregation(GO:0070487)
2.3 6.9 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
2.2 15.1 GO:0071461 cellular response to redox state(GO:0071461)
1.6 4.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.5 16.6 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
1.4 4.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
1.4 5.4 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.2 3.6 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
1.1 12.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.0 6.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.0 5.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.9 2.8 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.9 2.8 GO:0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.9 2.8 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.8 4.2 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.7 2.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.7 2.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.7 4.1 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.7 3.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.6 3.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 3.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 1.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 3.5 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4 1.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4 1.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.4 4.3 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.4 2.7 GO:0051012 microtubule sliding(GO:0051012)
0.4 1.4 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.4 2.5 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 1.3 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.3 2.6 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.3 3.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.3 2.1 GO:1903232 melanosome assembly(GO:1903232)
0.3 4.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.3 0.9 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.3 1.9 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 4.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 1.3 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2 2.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 2.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 1.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 1.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 2.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.9 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.2 0.7 GO:0030070 insulin processing(GO:0030070)
0.2 0.8 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.2 2.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 0.8 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.2 1.8 GO:0003383 apical constriction(GO:0003383)
0.2 0.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.8 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 1.9 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2 2.3 GO:0021759 globus pallidus development(GO:0021759)
0.2 3.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 0.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.2 2.0 GO:2001181 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 0.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 3.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 1.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 0.5 GO:0061055 myotome development(GO:0061055)
0.2 6.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 0.5 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 1.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.7 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 1.7 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 1.8 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 1.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 5.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 2.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 5.5 GO:0010575 positive regulation of vascular endothelial growth factor production(GO:0010575)
0.1 0.8 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 1.6 GO:0051451 myoblast migration(GO:0051451)
0.1 0.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.1 18.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 0.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.2 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.5 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 1.6 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 1.0 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 1.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.9 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 2.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.6 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 1.0 GO:0015747 urate transport(GO:0015747)
0.1 3.1 GO:0045730 respiratory burst(GO:0045730)
0.1 0.4 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 2.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.7 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 2.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.7 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 1.9 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 0.7 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 1.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 3.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.6 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 2.1 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.4 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 2.5 GO:0002576 platelet degranulation(GO:0002576)
0.1 4.3 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.6 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.5 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 1.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 2.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 2.7 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.7 GO:0033227 dsRNA transport(GO:0033227)
0.0 4.8 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 3.8 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.8 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 1.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 1.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.8 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0050808 synapse organization(GO:0050808)
0.0 0.8 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.9 GO:0097205 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.0 0.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.6 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.5 GO:0006477 protein sulfation(GO:0006477)
0.0 1.7 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.8 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097)
0.0 0.7 GO:0048535 lymph node development(GO:0048535)
0.0 0.3 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 1.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.6 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 1.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 3.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 1.9 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.5 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 1.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 1.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0048290 isotype switching to IgA isotypes(GO:0048290)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.0 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 11.1 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.3 GO:0046649 lymphocyte activation(GO:0046649)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 2.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 2.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0097459 ferric iron import(GO:0033216) iron ion import into cell(GO:0097459) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) iron ion import across plasma membrane(GO:0098711)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.6 GO:1901215 negative regulation of neuron death(GO:1901215)
0.0 0.1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.4 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.6 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
2.5 19.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.9 2.8 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.8 4.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.8 4.0 GO:0031905 early endosome lumen(GO:0031905)
0.7 4.3 GO:0031673 H zone(GO:0031673)
0.5 2.0 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.5 1.4 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.5 1.8 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4 4.3 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.4 3.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 1.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.3 3.1 GO:0032010 phagolysosome(GO:0032010)
0.2 5.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 5.4 GO:0005922 connexon complex(GO:0005922)
0.2 17.0 GO:0045095 keratin filament(GO:0045095)
0.2 5.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 5.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 2.8 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 2.0 GO:0045179 apical cortex(GO:0045179)
0.1 1.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 0.6 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 1.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 4.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 18.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 5.7 GO:0001533 cornified envelope(GO:0001533)
0.1 0.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 3.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 4.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 3.9 GO:0005605 basal lamina(GO:0005605)
0.1 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 1.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 4.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 11.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.3 GO:0002177 manchette(GO:0002177)
0.1 0.9 GO:0032797 SMN complex(GO:0032797)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 1.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 3.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 15.9 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.4 GO:1990391 DNA repair complex(GO:1990391)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 2.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.6 GO:0042599 lamellar body(GO:0042599)
0.0 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 2.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 3.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.4 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 15.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.2 3.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
1.0 4.0 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.9 12.0 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.8 4.2 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.7 4.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6 6.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.5 5.4 GO:0045545 syndecan binding(GO:0045545)
0.5 13.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.5 2.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.5 18.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 2.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 16.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4 2.7 GO:0070728 leucine binding(GO:0070728)
0.4 1.9 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.4 1.9 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4 3.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 2.8 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.3 1.2 GO:0015616 DNA translocase activity(GO:0015616)
0.3 4.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 0.9 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.2 0.9 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.2 0.9 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 1.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.2 0.8 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 3.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 18.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 5.7 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.2 2.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 1.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 3.5 GO:0000150 recombinase activity(GO:0000150)
0.2 3.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 4.2 GO:0015643 toxic substance binding(GO:0015643)
0.2 3.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.5 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.2 1.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 2.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 18.5 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 3.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.7 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 2.1 GO:0017166 vinculin binding(GO:0017166)
0.1 4.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 5.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 2.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.0 GO:0005123 death receptor binding(GO:0005123)
0.1 4.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.5 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 3.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 1.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 2.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.8 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 22.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.7 GO:0032052 bile acid binding(GO:0032052)
0.1 1.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.5 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 1.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 2.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.3 GO:0016208 AMP binding(GO:0016208)
0.0 2.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 1.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 1.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 1.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 7.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 1.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 3.5 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 27.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 17.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 8.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 17.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 5.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 9.5 PID FGF PATHWAY FGF signaling pathway
0.1 2.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 6.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.8 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 4.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 3.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 3.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 3.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 3.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 18.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 7.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.3 2.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 5.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 3.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 1.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 3.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 6.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 4.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 17.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 6.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 3.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 3.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.5 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.1 1.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 15.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 3.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 3.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 3.1 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 7.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 3.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 3.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall