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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFIA

Z-value: 2.18

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Transcription factors associated with NFIA

Gene Symbol Gene ID Gene Info
ENSG00000162599.11 nuclear factor I A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIAhg19_v2_chr1_+_61330931_613310170.921.4e-08Click!

Activity profile of NFIA motif

Sorted Z-values of NFIA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_42947121 15.84 ENST00000601181.1
chemokine (C-X-C motif) ligand 17
chr18_+_61144160 13.20 ENST00000489441.1
ENST00000424602.1
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr12_-_52911718 12.48 ENST00000548409.1
keratin 5
chr18_+_61143994 12.42 ENST00000382771.4
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr7_-_41742697 12.00 ENST00000242208.4
inhibin, beta A
chr17_-_39661849 11.45 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
keratin 13
chr12_-_52914155 11.36 ENST00000549420.1
ENST00000551275.1
ENST00000546577.1
keratin 5
chr7_+_129932974 11.00 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr19_+_42254885 9.98 ENST00000595740.1
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr6_+_106959718 9.18 ENST00000369066.3
absent in melanoma 1
chr8_+_124194752 8.95 ENST00000318462.6
family with sequence similarity 83, member A
chr21_-_28215332 8.93 ENST00000517777.1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr13_+_78109884 8.78 ENST00000377246.3
ENST00000349847.3
sciellin
chr12_-_28125638 8.74 ENST00000545234.1
parathyroid hormone-like hormone
chr13_+_78109804 8.46 ENST00000535157.1
sciellin
chr11_+_34654011 8.44 ENST00000531794.1
ets homologous factor
chr8_+_124194875 8.34 ENST00000522648.1
ENST00000276699.6
family with sequence similarity 83, member A
chr17_-_39661947 7.44 ENST00000590425.1
keratin 13
chr17_-_39093672 7.29 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
keratin 23 (histone deacetylase inducible)
chr2_+_54684327 6.85 ENST00000389980.3
spectrin, beta, non-erythrocytic 1
chr18_+_61254221 6.59 ENST00000431153.1
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr19_-_43969796 6.35 ENST00000244333.3
LY6/PLAUR domain containing 3
chr11_-_118134997 6.21 ENST00000278937.2
myelin protein zero-like 2
chr18_+_61254570 6.14 ENST00000344731.5
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr2_-_113542063 5.96 ENST00000263339.3
interleukin 1, alpha
chr10_+_24528108 5.80 ENST00000438429.1
KIAA1217
chr1_+_209878182 5.74 ENST00000367027.3
hydroxysteroid (11-beta) dehydrogenase 1
chr2_-_31637560 5.60 ENST00000379416.3
xanthine dehydrogenase
chr18_+_61254534 5.58 ENST00000269489.5
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr6_-_56492816 5.53 ENST00000522360.1
dystonin
chr6_-_32784687 5.29 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr17_-_39769005 5.26 ENST00000301653.4
ENST00000593067.1
keratin 16
chr1_+_68150744 5.25 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr4_-_157892055 4.93 ENST00000422544.2
platelet derived growth factor C
chr3_+_121613265 4.93 ENST00000295605.2
solute carrier family 15 (oligopeptide transporter), member 2
chr1_-_39407467 4.89 ENST00000540558.1
rhomboid, veinlet-like 2 (Drosophila)
chr9_+_130911770 4.68 ENST00000372998.1
lipocalin 2
chr3_-_176914191 4.64 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
transducin (beta)-like 1 X-linked receptor 1
chr16_-_79634595 4.50 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr4_-_87028478 4.39 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr1_-_209792111 4.37 ENST00000455193.1
laminin, beta 3
chr11_+_34643600 4.21 ENST00000530286.1
ENST00000533754.1
ets homologous factor
chr1_-_39407450 4.20 ENST00000372990.1
rhomboid, veinlet-like 2 (Drosophila)
chr14_-_24732403 4.20 ENST00000206765.6
transglutaminase 1
chr12_-_53207842 4.16 ENST00000458244.2
keratin 4
chr4_+_30721968 4.15 ENST00000361762.2
protocadherin 7
chr3_-_105588231 4.12 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr9_+_130911723 4.08 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr10_-_126138622 4.06 ENST00000451024.3
NK1 homeobox 2
chr4_-_157892167 4.03 ENST00000541126.1
platelet derived growth factor C
chr16_+_82090028 4.03 ENST00000568090.1
hydroxysteroid (17-beta) dehydrogenase 2
chr18_+_20494078 4.00 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
retinoblastoma binding protein 8
chr5_-_141249154 3.95 ENST00000357517.5
ENST00000536585.1
protocadherin 1
chr14_-_24732368 3.81 ENST00000544573.1
transglutaminase 1
chr1_+_95975672 3.81 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
chr12_+_56324756 3.71 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chr2_+_17721230 3.70 ENST00000457525.1
visinin-like 1
chr2_-_163099885 3.67 ENST00000443424.1
fibroblast activation protein, alpha
chr6_-_30043539 3.60 ENST00000376751.3
ENST00000244360.6
ring finger protein 39
chr6_+_108977520 3.59 ENST00000540898.1
forkhead box O3
chr14_+_71165292 3.54 ENST00000553682.1
RP6-65G23.1
chr2_-_163100045 3.47 ENST00000188790.4
fibroblast activation protein, alpha
chr5_+_3596168 3.41 ENST00000302006.3
iroquois homeobox 1
chr1_+_24646002 3.34 ENST00000356046.2
grainyhead-like 3 (Drosophila)
chr7_-_17598506 3.30 ENST00000451792.1
AC017060.1
chr17_-_38657849 3.27 ENST00000254051.6
tensin 4
chr11_-_61101247 3.27 ENST00000543627.1
damage-specific DNA binding protein 1, 127kDa
chr14_-_36988882 3.25 ENST00000498187.2
NK2 homeobox 1
chr1_+_44399347 3.21 ENST00000477048.1
ENST00000471394.2
artemin
chr14_-_75079026 3.21 ENST00000261978.4
latent transforming growth factor beta binding protein 2
chr14_-_69350920 3.20 ENST00000553290.1
actinin, alpha 1
chr3_-_74570291 3.20 ENST00000263665.6
contactin 3 (plasmacytoma associated)
chr11_-_58343319 3.15 ENST00000395074.2
leupaxin
chr11_-_13461790 3.13 ENST00000530907.1
BTB (POZ) domain containing 10
chr12_+_8995832 3.10 ENST00000541459.1
alpha-2-macroglobulin-like 1
chr7_-_24957699 3.07 ENST00000441059.1
ENST00000415162.1
oxysterol binding protein-like 3
chr13_-_40177261 2.98 ENST00000379589.3
lipoma HMGIC fusion partner
chr4_+_146402925 2.97 ENST00000302085.4
SMAD family member 1
chr5_-_74807418 2.95 ENST00000405807.4
ENST00000261415.7
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr16_-_66785497 2.93 ENST00000440564.2
ENST00000379482.2
ENST00000443351.2
ENST00000566150.1
dynein, cytoplasmic 1, light intermediate chain 2
chr8_-_42358742 2.90 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr16_-_65106110 2.86 ENST00000562882.1
ENST00000567934.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr11_-_35547151 2.80 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
peptidase domain containing associated with muscle regeneration 1
chr1_+_24645915 2.77 ENST00000350501.5
grainyhead-like 3 (Drosophila)
chr7_-_151330218 2.77 ENST00000476632.1
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr10_+_135340859 2.75 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr2_-_214013353 2.74 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKAROS family zinc finger 2 (Helios)
chr17_-_74533963 2.73 ENST00000293230.5
cytoglobin
chr12_+_56324933 2.73 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr1_+_44399466 2.66 ENST00000498139.2
ENST00000491846.1
artemin
chr1_+_24646263 2.66 ENST00000524724.1
grainyhead-like 3 (Drosophila)
chr9_-_99064386 2.61 ENST00000375262.2
hydroxysteroid (17-beta) dehydrogenase 3
chr6_-_56716686 2.57 ENST00000520645.1
dystonin
chr17_+_7461580 2.56 ENST00000483039.1
ENST00000396542.1
tumor necrosis factor (ligand) superfamily, member 13
chr2_+_102953608 2.55 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr9_-_99064429 2.55 ENST00000375263.3
hydroxysteroid (17-beta) dehydrogenase 3
chr18_-_47792851 2.54 ENST00000398545.4
coiled-coil domain containing 11
chr12_+_110718428 2.54 ENST00000552636.1
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr22_-_38699003 2.54 ENST00000451964.1
casein kinase 1, epsilon
chr17_+_7462031 2.53 ENST00000380535.4
tumor necrosis factor (ligand) superfamily, member 13
chr5_+_112073544 2.52 ENST00000257430.4
ENST00000508376.2
adenomatous polyposis coli
chr14_-_75078725 2.50 ENST00000556690.1
latent transforming growth factor beta binding protein 2
chr3_-_93747425 2.49 ENST00000315099.2
syntaxin 19
chr3_+_184032919 2.46 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
eukaryotic translation initiation factor 4 gamma, 1
chr1_+_110546700 2.45 ENST00000359172.3
ENST00000393614.4
adenosylhomocysteinase-like 1
chr1_+_10093188 2.41 ENST00000377153.1
ubiquitination factor E4B
chr11_-_128392085 2.39 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr20_-_45985464 2.36 ENST00000458360.2
ENST00000262975.4
zinc finger, MYND-type containing 8
chr10_+_24755416 2.36 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr8_+_123875624 2.35 ENST00000534247.1
zinc fingers and homeoboxes 2
chr12_+_56325231 2.35 ENST00000549368.1
diacylglycerol kinase, alpha 80kDa
chr17_+_79027155 2.34 ENST00000572918.1
BAI1-associated protein 2
chr2_+_192543694 2.34 ENST00000435931.1
nucleic acid binding protein 1
chr10_-_25010795 2.32 ENST00000416305.1
ENST00000376410.2
Rho GTPase activating protein 21
chr3_-_69402828 2.31 ENST00000460709.1
FERM domain containing 4B
chr4_+_169552748 2.30 ENST00000504519.1
ENST00000512127.1
palladin, cytoskeletal associated protein
chr4_-_57547870 2.30 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr3_+_152017924 2.27 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
muscleblind-like splicing regulator 1
chrX_+_69642881 2.26 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
glycerophosphodiester phosphodiesterase domain containing 2
chr3_+_184033551 2.26 ENST00000456033.1
eukaryotic translation initiation factor 4 gamma, 1
chr3_-_176914238 2.25 ENST00000430069.1
ENST00000428970.1
transducin (beta)-like 1 X-linked receptor 1
chr3_-_171177852 2.21 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TRAF2 and NCK interacting kinase
chr20_-_45985414 2.21 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
zinc finger, MYND-type containing 8
chr11_-_122931881 2.20 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr20_-_45985172 2.18 ENST00000536340.1
zinc finger, MYND-type containing 8
chr5_+_36608422 2.13 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_204116078 2.09 ENST00000367198.2
ENST00000452983.1
ethanolamine kinase 2
chr2_-_99485825 2.08 ENST00000423771.1
KIAA1211-like
chr5_+_150157860 2.07 ENST00000600109.1
AC010441.1
chr2_-_160761179 2.07 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
lymphocyte antigen 75
LY75-CD302 readthrough
chr11_+_20044375 2.06 ENST00000525322.1
ENST00000530408.1
neuron navigator 2
chr14_-_85996332 2.03 ENST00000380722.1
RP11-497E19.1
chr5_-_41794663 2.03 ENST00000510634.1
3-oxoacid CoA transferase 1
chr17_+_79031415 2.03 ENST00000572073.1
ENST00000573677.1
BAI1-associated protein 2
chr5_+_150157444 2.03 ENST00000526627.1
small integral membrane protein 3
chr10_+_11206925 2.01 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CUGBP, Elav-like family member 2
chr6_-_86353510 2.01 ENST00000444272.1
synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_+_43603229 2.01 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr8_-_28243934 2.01 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr4_-_87770416 2.00 ENST00000273905.6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr6_+_26158343 1.97 ENST00000377777.4
ENST00000289316.2
histone cluster 1, H2bd
chr5_+_122847908 1.96 ENST00000511130.2
ENST00000512718.3
casein kinase 1, gamma 3
chr17_+_7461849 1.93 ENST00000338784.4
tumor necrosis factor (ligand) superfamily, member 13
chr9_+_470288 1.91 ENST00000382303.1
KN motif and ankyrin repeat domains 1
chr11_-_16430399 1.90 ENST00000528252.1
SRY (sex determining region Y)-box 6
chr1_+_174933899 1.90 ENST00000367688.3
RAB GTPase activating protein 1-like
chr11_-_46639436 1.89 ENST00000532281.1
harbinger transposase derived 1
chr11_+_118477144 1.89 ENST00000361417.2
pleckstrin homology-like domain, family B, member 1
chr6_+_21593972 1.89 ENST00000244745.1
ENST00000543472.1
SRY (sex determining region Y)-box 4
chr5_+_43602750 1.88 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
nicotinamide nucleotide transhydrogenase
chr16_-_19725899 1.85 ENST00000567367.1
lysine-rich nucleolar protein 1
chr1_+_33231221 1.85 ENST00000294521.3
KIAA1522
chr2_-_33824336 1.85 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
family with sequence similarity 98, member A
chr17_+_7461781 1.84 ENST00000349228.4
tumor necrosis factor (ligand) superfamily, member 13
chr3_+_184033135 1.84 ENST00000424196.1
eukaryotic translation initiation factor 4 gamma, 1
chr2_+_136289030 1.84 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3H domain containing 1
chr17_-_74533734 1.83 ENST00000589342.1
cytoglobin
chr10_-_27149851 1.81 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
abl-interactor 1
chr4_-_187517928 1.81 ENST00000512772.1
FAT atypical cadherin 1
chr5_-_168006324 1.80 ENST00000522176.1
pantothenate kinase 3
chr14_+_58797974 1.80 ENST00000417477.2
AT rich interactive domain 4A (RBP1-like)
chr7_-_129592471 1.79 ENST00000473814.2
ENST00000490974.1
ubiquitin-conjugating enzyme E2H
chr5_-_124082279 1.79 ENST00000513986.1
zinc finger protein 608
chr1_+_15986364 1.79 ENST00000345034.1
regulatory solute carrier protein, family 1, member 1
chr2_+_192141611 1.78 ENST00000392316.1
myosin IB
chr5_-_43313269 1.76 ENST00000511774.1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr11_+_20044096 1.76 ENST00000533917.1
neuron navigator 2
chr11_-_59383617 1.74 ENST00000263847.1
oxysterol binding protein
chr10_-_27149904 1.74 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
abl-interactor 1
chr17_+_7462103 1.72 ENST00000396545.4
tumor necrosis factor (ligand) superfamily, member 13
chr16_-_4164027 1.71 ENST00000572288.1
adenylate cyclase 9
chr2_-_114300213 1.70 ENST00000446595.1
ENST00000416105.1
ENST00000450636.1
ENST00000416758.1
RP11-395L14.4
chr13_-_20805109 1.67 ENST00000241124.6
gap junction protein, beta 6, 30kDa
chr11_-_118023490 1.67 ENST00000324727.4
sodium channel, voltage-gated, type IV, beta subunit
chr12_+_19389814 1.66 ENST00000536974.1
pleckstrin homology domain containing, family A member 5
chr5_+_112074029 1.66 ENST00000512211.2
adenomatous polyposis coli
chr9_+_109685630 1.65 ENST00000451160.2
Uncharacterized protein
chr8_-_116504448 1.64 ENST00000518018.1
trichorhinophalangeal syndrome I
chr11_-_2170786 1.64 ENST00000300632.5
insulin-like growth factor 2 (somatomedin A)
chrX_+_22050546 1.63 ENST00000379374.4
phosphate regulating endopeptidase homolog, X-linked
chr12_+_40787194 1.63 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr13_-_46742630 1.62 ENST00000416500.1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_50678921 1.62 ENST00000230658.7
ISL LIM homeobox 1
chr6_-_122792919 1.61 ENST00000339697.4
serine incorporator 1
chr7_+_17338239 1.60 ENST00000242057.4
aryl hydrocarbon receptor
chr2_-_26467465 1.60 ENST00000457468.2
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr3_+_186501979 1.60 ENST00000498746.1
eukaryotic translation initiation factor 4A2
chr6_-_143266297 1.60 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr16_+_15737124 1.60 ENST00000396355.1
ENST00000396353.2
nudE neurodevelopment protein 1
chr7_-_83824169 1.59 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_101188718 1.57 ENST00000299222.9
ENST00000392977.3
anoctamin 4
chr11_+_118230287 1.57 ENST00000252108.3
ENST00000431736.2
ubiquitination factor E4A
chr4_+_144354644 1.56 ENST00000512843.1
GRB2-associated binding protein 1
chr4_+_169633310 1.56 ENST00000510998.1
palladin, cytoskeletal associated protein
chr11_-_61348292 1.55 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
synaptotagmin VII
chr17_-_62308087 1.55 ENST00000583097.1
testis expressed 2
chr5_-_41794313 1.53 ENST00000512084.1
3-oxoacid CoA transferase 1
chrX_+_64808248 1.51 ENST00000609672.1
moesin
chr4_+_3076388 1.48 ENST00000355072.5
huntingtin
chr14_-_50319758 1.45 ENST00000298310.5
nuclear export mediator factor

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
4.0 12.0 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
2.7 8.0 GO:1902362 melanocyte apoptotic process(GO:1902362)
1.8 5.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.8 8.8 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.4 5.6 GO:0046110 xanthine metabolic process(GO:0046110)
1.2 3.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.1 8.0 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
1.1 6.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.1 20.0 GO:0043587 tongue morphogenesis(GO:0043587)
1.0 4.0 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.0 12.0 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
1.0 2.9 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
1.0 5.9 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.9 3.4 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.8 2.5 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.8 28.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.8 6.8 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.7 6.0 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.7 1.5 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.7 15.4 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.7 2.8 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.7 3.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.7 4.6 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.6 1.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.6 3.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.6 5.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.6 3.9 GO:0006740 NADPH regeneration(GO:0006740)
0.5 9.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.5 8.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.5 2.4 GO:0008050 female courtship behavior(GO:0008050)
0.5 4.4 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.5 3.8 GO:0021564 vagus nerve development(GO:0021564)
0.5 3.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.5 1.9 GO:0035905 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.5 6.9 GO:0060613 fat pad development(GO:0060613)
0.5 0.9 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 3.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.4 14.0 GO:0061436 establishment of skin barrier(GO:0061436)
0.4 6.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.4 0.9 GO:0042704 uterine wall breakdown(GO:0042704)
0.4 4.9 GO:0006857 oligopeptide transport(GO:0006857)
0.4 21.7 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.4 2.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.4 1.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.4 1.6 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.4 1.5 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.4 2.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.4 1.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.3 3.8 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.3 2.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 2.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 2.6 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.3 1.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.3 3.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 4.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 1.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 2.4 GO:0072553 terminal button organization(GO:0072553)
0.3 2.4 GO:0030578 PML body organization(GO:0030578)
0.3 3.9 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 0.8 GO:0061386 closure of optic fissure(GO:0061386)
0.3 1.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.3 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 3.2 GO:0021759 globus pallidus development(GO:0021759)
0.3 1.6 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.3 6.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.3 1.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 5.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 1.4 GO:0001575 globoside metabolic process(GO:0001575)
0.2 2.4 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.2 2.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 0.9 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 2.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 2.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 5.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 1.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.2 1.4 GO:0051012 microtubule sliding(GO:0051012)
0.2 9.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 4.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 5.2 GO:0030539 male genitalia development(GO:0030539)
0.2 1.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 0.7 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.2 1.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 2.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 1.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 0.7 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 4.9 GO:0035855 megakaryocyte development(GO:0035855)
0.2 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 3.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 4.4 GO:0051639 actin filament network formation(GO:0051639)
0.2 8.8 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.2 0.8 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.6 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.3 GO:0000023 maltose metabolic process(GO:0000023)
0.1 1.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 3.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.5 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.1 0.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 3.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 1.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.0 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 1.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.7 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 2.9 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.6 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 1.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 3.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 3.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 2.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.1 GO:0021603 cranial nerve formation(GO:0021603)
0.1 1.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 6.0 GO:0097435 fibril organization(GO:0097435)
0.1 2.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.1 3.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.9 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.5 GO:0051168 nuclear export(GO:0051168)
0.1 4.9 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 19.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.5 GO:0001555 oocyte growth(GO:0001555)
0.1 9.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.2 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 22.9 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 1.7 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 2.9 GO:0051642 centrosome localization(GO:0051642)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.3 GO:0072189 ureter development(GO:0072189)
0.1 1.4 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.1 3.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.6 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.1 4.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.8 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.2 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 0.4 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 1.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 1.0 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 12.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.6 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.6 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 1.8 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 1.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 9.9 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 1.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0055065 metal ion homeostasis(GO:0055065)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.3 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.9 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 1.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.8 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 1.2 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.7 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 1.1 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 1.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 2.3 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 3.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 3.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.0 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 1.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 3.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.8 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 1.0 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.4 GO:0032026 response to magnesium ion(GO:0032026)
0.0 1.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 2.4 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052)
0.0 0.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 2.6 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 3.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0030261 chromosome condensation(GO:0030261)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
1.4 8.1 GO:0031673 H zone(GO:0031673)
0.9 6.9 GO:0032437 cuticular plate(GO:0032437)
0.5 46.7 GO:0045095 keratin filament(GO:0045095)
0.4 8.0 GO:0071438 invadopodium membrane(GO:0071438)
0.4 3.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.4 4.4 GO:0005610 laminin-5 complex(GO:0005610)
0.4 1.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.3 1.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 24.8 GO:0001533 cornified envelope(GO:0001533)
0.3 1.6 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.3 1.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.3 1.2 GO:0070939 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.3 2.3 GO:0070876 SOSS complex(GO:0070876)
0.3 1.1 GO:0043293 apoptosome(GO:0043293)
0.3 2.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 4.9 GO:0031209 SCAR complex(GO:0031209)
0.3 3.2 GO:0005916 fascia adherens(GO:0005916)
0.3 1.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.3 2.0 GO:0097452 GAIT complex(GO:0097452)
0.2 4.2 GO:1990909 Wnt signalosome(GO:1990909)
0.2 1.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 5.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.3 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 2.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 5.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 0.6 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 2.5 GO:0097470 ribbon synapse(GO:0097470)
0.2 1.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 3.1 GO:0032433 filopodium tip(GO:0032433)
0.2 1.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 13.3 GO:0005882 intermediate filament(GO:0005882)
0.1 1.6 GO:0032009 early phagosome(GO:0032009)
0.1 2.0 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 1.3 GO:0030478 actin cap(GO:0030478)
0.1 1.0 GO:0070695 FHF complex(GO:0070695)
0.1 10.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.4 GO:0031905 early endosome lumen(GO:0031905)
0.1 6.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 9.4 GO:0002102 podosome(GO:0002102)
0.1 19.3 GO:0043202 lysosomal lumen(GO:0043202)
0.1 2.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.9 GO:0045180 basal cortex(GO:0045180)
0.1 16.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 9.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.5 GO:0071437 invadopodium(GO:0071437)
0.1 3.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.6 GO:0071141 SMAD protein complex(GO:0071141)
0.1 2.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 2.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.7 GO:0005922 connexon complex(GO:0005922)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 5.1 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 5.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.0 4.6 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.1 GO:0005604 basement membrane(GO:0005604)
0.0 6.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.0 GO:0030424 axon(GO:0030424)
0.0 2.0 GO:0031201 SNARE complex(GO:0031201)
0.0 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134) endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 3.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 3.1 GO:0005884 actin filament(GO:0005884)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 1.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 2.3 GO:0043679 axon terminus(GO:0043679)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 3.3 GO:0055037 recycling endosome(GO:0055037)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 1.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0016234 inclusion body(GO:0016234)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 3.3 GO:0001726 ruffle(GO:0001726)
0.0 1.9 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 12.0 GO:0070699 type II activin receptor binding(GO:0070699)
1.9 5.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.3 3.9 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
1.1 4.6 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.9 3.6 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.9 2.6 GO:0002113 interleukin-33 binding(GO:0002113)
0.8 2.5 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.8 18.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.8 4.9 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.7 2.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.6 5.6 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.6 8.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 2.9 GO:0097001 ceramide binding(GO:0097001)
0.5 2.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 1.6 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.4 1.2 GO:0019961 interferon binding(GO:0019961)
0.4 2.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 3.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.9 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.4 4.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 1.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3 2.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 2.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 47.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 14.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 5.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 6.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 11.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 3.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 2.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 3.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.3 3.9 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.3 1.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 2.8 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 7.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 9.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 1.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 2.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 6.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 0.7 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.2 8.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 24.9 GO:0097110 scaffold protein binding(GO:0097110)
0.2 10.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.9 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 0.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 4.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 4.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 2.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 4.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 1.7 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.8 GO:0003883 CTP synthase activity(GO:0003883)
0.1 3.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.6 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 1.3 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.1 3.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 6.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 3.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 3.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.1 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 5.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 6.3 GO:0043236 laminin binding(GO:0043236)
0.1 3.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.7 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 3.2 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.1 1.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 1.5 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 1.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 5.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 3.0 GO:0017166 vinculin binding(GO:0017166)
0.1 2.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.1 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.1 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.3 GO:0031751 D2 dopamine receptor binding(GO:0031749) D4 dopamine receptor binding(GO:0031751)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 2.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 12.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 10.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.1 1.1 GO:0070513 death domain binding(GO:0070513)
0.1 3.0 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 4.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.9 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 2.0 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 1.0 GO:0030674 protein binding, bridging(GO:0030674) binding, bridging(GO:0060090)
0.1 1.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 8.1 GO:0002020 protease binding(GO:0002020)
0.0 2.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 1.8 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 2.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 3.7 GO:0044212 regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212)
0.0 1.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 31.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 5.2 GO:0004386 helicase activity(GO:0004386)
0.0 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 2.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 1.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 14.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 3.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 1.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 11.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 39.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 16.7 PID ALK1 PATHWAY ALK1 signaling events
0.2 10.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 7.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 15.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 16.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 4.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 10.3 PID FOXO PATHWAY FoxO family signaling
0.1 35.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 8.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 9.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 4.0 PID BARD1 PATHWAY BARD1 signaling events
0.1 5.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 6.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 14.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 4.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 4.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.5 PID P73PATHWAY p73 transcription factor network
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.4 8.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 4.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 5.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 6.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 10.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 5.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 6.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 5.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 3.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 4.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 3.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 4.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 13.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 1.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 7.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 4.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 3.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.6 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.1 4.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 1.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 6.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 10.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 8.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 3.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 3.7 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 1.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 2.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation