Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for NFKB2

Z-value: 1.12

Motif logo

logo of

Transcription factors associated with NFKB2

Gene Symbol Gene ID Gene Info
NFKB2
ENSG00000077150.13 nuclear factor kappa B subunit 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB2hg19_v2_chr10_+_104154229_1041543540.642.3e-03Click!

Activity profile of NFKB2 motif

Sorted Z-values of NFKB2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_43803517 3.41 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr4_-_74904398 2.90 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr9_+_130911723 2.75 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr4_-_74964904 2.39 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr9_+_130911770 2.33 ENST00000372998.1
LCN2
lipocalin 2
chr4_+_74735102 2.26 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr17_-_34207295 1.82 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr16_+_89753070 1.77 ENST00000353379.7
ENST00000505473.1
ENST00000564192.1
CDK10
cyclin-dependent kinase 10
chr14_-_24616426 1.46 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr6_-_31138439 1.39 ENST00000259915.8
POU5F1
POU class 5 homeobox 1
chr19_+_859654 1.38 ENST00000592860.1
CFD
complement factor D (adipsin)
chr7_+_1570322 1.33 ENST00000343242.4
MAFK
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr10_-_7708918 1.31 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr6_-_31324943 1.29 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr13_-_111214015 1.28 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr8_-_66754172 1.26 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr9_-_139948487 1.25 ENST00000355097.2
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr9_+_135037334 1.23 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr3_+_126243126 1.23 ENST00000319340.2
CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr1_-_186649543 1.22 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr19_+_18544045 1.21 ENST00000599699.2
SSBP4
single stranded DNA binding protein 4
chr9_-_139948468 1.19 ENST00000312665.5
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr14_-_24615805 1.18 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr8_-_145641864 1.17 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_-_32229523 1.17 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
BAI2
brain-specific angiogenesis inhibitor 2
chr10_+_104154229 1.16 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr9_-_140115775 1.11 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr11_-_18270182 1.07 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr5_-_176730676 1.07 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr5_-_176730733 1.02 ENST00000504395.1
RAB24
RAB24, member RAS oncogene family
chr12_+_56473628 0.99 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr11_-_57335750 0.97 ENST00000340573.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr11_+_60691924 0.95 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr4_-_74864386 0.94 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr6_-_30080876 0.94 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr12_+_120740119 0.94 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr9_+_130922537 0.93 ENST00000372994.1
C9orf16
chromosome 9 open reading frame 16
chr22_-_25801333 0.88 ENST00000444995.3
LRP5L
low density lipoprotein receptor-related protein 5-like
chr11_+_119056178 0.86 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr6_-_30080863 0.86 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr16_-_88923285 0.85 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr3_-_50340996 0.82 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr8_-_144923112 0.81 ENST00000442628.2
NRBP2
nuclear receptor binding protein 2
chr1_+_186649754 0.80 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr11_+_818902 0.80 ENST00000336615.4
PNPLA2
patatin-like phospholipase domain containing 2
chr5_+_98264867 0.80 ENST00000513175.1
CTD-2007H13.3
CTD-2007H13.3
chr1_-_32229934 0.80 ENST00000398542.1
BAI2
brain-specific angiogenesis inhibitor 2
chr19_+_45504688 0.80 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr12_-_58131931 0.78 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_-_27682962 0.77 ENST00000486046.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr19_-_8567478 0.77 ENST00000255612.3
PRAM1
PML-RARA regulated adaptor molecule 1
chr11_+_72525353 0.75 ENST00000321297.5
ENST00000534905.1
ENST00000540567.1
ATG16L2
autophagy related 16-like 2 (S. cerevisiae)
chr12_+_7023491 0.74 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr14_-_24615523 0.74 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr19_-_52227221 0.73 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr11_-_76381781 0.73 ENST00000260061.5
ENST00000404995.1
LRRC32
leucine rich repeat containing 32
chr1_+_24117627 0.72 ENST00000400061.1
LYPLA2
lysophospholipase II
chr11_-_61197480 0.72 ENST00000439958.3
ENST00000394888.4
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr22_+_17082732 0.71 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr11_-_64570706 0.70 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr11_-_65641044 0.69 ENST00000527378.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr16_-_88878305 0.69 ENST00000569616.1
ENST00000563655.1
ENST00000567713.1
ENST00000426324.2
ENST00000378364.3
APRT
adenine phosphoribosyltransferase
chr1_-_42921915 0.69 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chr5_-_137090028 0.68 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr12_-_62997214 0.68 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr19_-_47734448 0.67 ENST00000439096.2
BBC3
BCL2 binding component 3
chr12_+_120502441 0.67 ENST00000446727.2
CCDC64
coiled-coil domain containing 64
chr7_-_5463175 0.67 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr19_-_55677999 0.67 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3
dynein, axonemal, assembly factor 3
chr12_+_56473939 0.66 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr19_+_55795493 0.65 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr19_+_35485682 0.65 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr12_+_70760056 0.64 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr11_-_61560053 0.64 ENST00000537328.1
TMEM258
transmembrane protein 258
chr19_-_55677920 0.64 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr1_+_244624678 0.64 ENST00000366534.4
ENST00000366533.4
ENST00000428042.1
ENST00000366531.3
C1orf101
chromosome 1 open reading frame 101
chr10_+_112257596 0.63 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr2_+_71162995 0.63 ENST00000234396.4
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr11_-_104840093 0.63 ENST00000417440.2
ENST00000444739.2
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr5_-_179780312 0.61 ENST00000253778.8
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr3_+_51705222 0.61 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
TEX264
testis expressed 264
chr8_+_22941868 0.61 ENST00000397703.2
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr19_-_55881741 0.61 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr22_-_21984282 0.61 ENST00000398873.3
ENST00000292778.6
YDJC
YdjC homolog (bacterial)
chrX_-_118986911 0.60 ENST00000276201.2
ENST00000345865.2
UPF3B
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr8_-_145582118 0.60 ENST00000455319.2
ENST00000331890.5
FBXL6
F-box and leucine-rich repeat protein 6
chr19_+_41860047 0.60 ENST00000604123.1
TMEM91
transmembrane protein 91
chr19_+_46367518 0.59 ENST00000302177.2
FOXA3
forkhead box A3
chr11_-_61560254 0.59 ENST00000543510.1
TMEM258
transmembrane protein 258
chr14_+_23299088 0.59 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr1_+_901847 0.59 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr12_-_54673871 0.58 ENST00000209875.4
CBX5
chromobox homolog 5
chr2_+_71163051 0.58 ENST00000412314.1
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr20_-_3154162 0.57 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr2_-_206950781 0.56 ENST00000403263.1
INO80D
INO80 complex subunit D
chr17_+_46970134 0.56 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr2_+_132044330 0.55 ENST00000416266.1
CYP4F31P
cytochrome P450, family 4, subfamily F, polypeptide 31, pseudogene
chr17_+_66255310 0.55 ENST00000448504.2
ARSG
arylsulfatase G
chr19_-_50400212 0.55 ENST00000391826.2
IL4I1
interleukin 4 induced 1
chr17_+_46970127 0.55 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr11_-_33891362 0.55 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_+_78354243 0.55 ENST00000294624.8
NEXN
nexilin (F actin binding protein)
chr5_+_60240943 0.54 ENST00000296597.5
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr19_+_45251804 0.54 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr11_-_2924720 0.53 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr11_-_62380199 0.53 ENST00000419857.1
ENST00000394773.2
EML3
echinoderm microtubule associated protein like 3
chr19_+_19639704 0.53 ENST00000514277.4
YJEFN3
YjeF N-terminal domain containing 3
chr4_+_2043689 0.53 ENST00000382878.3
ENST00000409248.4
C4orf48
chromosome 4 open reading frame 48
chr6_-_43484718 0.53 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr10_+_124030819 0.53 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr8_-_90769939 0.53 ENST00000504145.1
ENST00000519655.2
RP11-37B2.1
RP11-37B2.1
chr12_+_57998595 0.53 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
DTX3
deltex homolog 3 (Drosophila)
chr14_-_23299009 0.52 ENST00000488800.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_+_75032901 0.52 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr12_+_123319973 0.52 ENST00000253083.4
HIP1R
huntingtin interacting protein 1 related
chr12_+_56109810 0.51 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
RP11-644F5.10
BLOC1S1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr20_-_48532019 0.51 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr8_-_103668114 0.51 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr19_-_41859814 0.51 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr8_-_90769422 0.51 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
RP11-37B2.1
chr19_+_1248547 0.50 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chr19_+_19639670 0.50 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr18_+_44812072 0.50 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
CTD-2130O13.1
chr5_-_178772424 0.50 ENST00000251582.7
ENST00000274609.5
ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr10_+_48189612 0.50 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr12_+_58003935 0.49 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr16_-_89752965 0.49 ENST00000567544.1
RP11-368I7.4
Uncharacterized protein
chr19_+_13135790 0.49 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_43380459 0.49 ENST00000299240.6
ENST00000039989.4
TTC17
tetratricopeptide repeat domain 17
chr20_-_62462566 0.49 ENST00000245663.4
ENST00000302995.2
ZBTB46
zinc finger and BTB domain containing 46
chr5_+_174151536 0.49 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr17_-_46671323 0.49 ENST00000239151.5
HOXB5
homeobox B5
chrX_+_68048803 0.49 ENST00000204961.4
EFNB1
ephrin-B1
chr19_+_35940486 0.48 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr19_+_48824711 0.48 ENST00000599704.1
EMP3
epithelial membrane protein 3
chr12_+_57916584 0.48 ENST00000546632.1
ENST00000549623.1
ENST00000431731.2
MBD6
methyl-CpG binding domain protein 6
chr19_-_33716750 0.48 ENST00000253188.4
SLC7A10
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chr3_+_96533621 0.48 ENST00000542517.1
ENST00000506569.1
EPHA6
EPH receptor A6
chr17_+_76165213 0.47 ENST00000590201.1
SYNGR2
synaptogyrin 2
chr20_-_25207370 0.47 ENST00000593352.1
AL035252.1
HCG2018895; Uncharacterized protein
chr19_+_50191921 0.47 ENST00000420022.3
ADM5
adrenomedullin 5 (putative)
chr17_-_7123021 0.47 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr10_+_22605304 0.46 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr12_-_57352103 0.46 ENST00000398138.3
RDH16
retinol dehydrogenase 16 (all-trans)
chr1_+_25943959 0.46 ENST00000374332.4
MAN1C1
mannosidase, alpha, class 1C, member 1
chr1_-_38100539 0.46 ENST00000401069.1
RSPO1
R-spondin 1
chr17_+_76164639 0.46 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
SYNGR2
synaptogyrin 2
chr12_-_124457257 0.46 ENST00000545891.1
CCDC92
coiled-coil domain containing 92
chr1_+_110453203 0.45 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr12_+_124997766 0.45 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr12_-_124457371 0.45 ENST00000238156.3
ENST00000545037.1
CCDC92
coiled-coil domain containing 92
chr12_-_56753858 0.45 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr16_+_28834303 0.45 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L
ataxin 2-like
chr16_-_4466565 0.45 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7
CORO7-PAM16 readthrough
coronin 7
chr19_+_38794797 0.44 ENST00000301246.5
ENST00000588605.1
C19orf33
chromosome 19 open reading frame 33
chr17_+_46970178 0.44 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr9_+_134103496 0.44 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr14_+_100705322 0.44 ENST00000262238.4
YY1
YY1 transcription factor
chr1_-_6545502 0.43 ENST00000535355.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_+_207494853 0.43 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr7_+_149412094 0.43 ENST00000255992.10
ENST00000319551.8
KRBA1
KRAB-A domain containing 1
chr17_+_28884130 0.43 ENST00000580161.1
TBC1D29
TBC1 domain family, member 29
chr1_-_45965525 0.43 ENST00000488405.2
ENST00000490551.3
ENST00000432082.1
CCDC163P
coiled-coil domain containing 163, pseudogene
chr8_+_145582217 0.43 ENST00000530047.1
ENST00000527078.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr16_-_57318566 0.43 ENST00000569059.1
ENST00000219207.5
PLLP
plasmolipin
chr22_+_50781723 0.43 ENST00000359139.3
ENST00000395741.3
ENST00000395744.3
PPP6R2
protein phosphatase 6, regulatory subunit 2
chr15_+_92937058 0.43 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr12_-_94673956 0.43 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr7_+_123485102 0.43 ENST00000488323.1
ENST00000223026.4
HYAL4
hyaluronoglucosaminidase 4
chr6_-_32157947 0.42 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr3_+_49058444 0.42 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr16_-_4303767 0.42 ENST00000573268.1
ENST00000573042.1
RP11-95P2.1
RP11-95P2.1
chr20_-_62258394 0.42 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chr1_-_2126174 0.42 ENST00000400919.3
ENST00000420515.1
ENST00000378543.2
ENST00000400918.3
C1orf86
chromosome 1 open reading frame 86
chr18_+_43914159 0.42 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr4_-_860950 0.41 ENST00000511980.1
ENST00000510799.1
GAK
cyclin G associated kinase
chr12_+_90674665 0.41 ENST00000549313.1
RP11-753N8.1
RP11-753N8.1
chr6_-_43484621 0.41 ENST00000506469.1
ENST00000503972.1
YIPF3
Yip1 domain family, member 3
chr10_+_22605374 0.41 ENST00000448361.1
COMMD3
COMM domain containing 3
chr11_+_61197572 0.41 ENST00000542074.1
ENST00000534878.1
ENST00000537782.1
ENST00000543265.1
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr17_+_38024417 0.41 ENST00000348931.4
ENST00000583811.1
ENST00000584588.1
ENST00000377940.3
ZPBP2
zona pellucida binding protein 2
chr19_-_1885432 0.40 ENST00000250974.9
ABHD17A
abhydrolase domain containing 17A
chr1_-_2126192 0.40 ENST00000378546.4
C1orf86
chromosome 1 open reading frame 86
chr8_+_90769967 0.40 ENST00000220751.4
RIPK2
receptor-interacting serine-threonine kinase 2
chr5_+_56469775 0.40 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr10_-_47239738 0.40 ENST00000413193.2
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr1_+_45274154 0.40 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr19_-_5978144 0.40 ENST00000340578.6
ENST00000541471.1
ENST00000591736.1
ENST00000587479.1
RANBP3
RAN binding protein 3
chr20_+_33462888 0.39 ENST00000336325.4
ACSS2
acyl-CoA synthetase short-chain family member 2
chr18_+_43913973 0.39 ENST00000590330.1
RNF165
ring finger protein 165
chr9_-_130700080 0.39 ENST00000373110.4
DPM2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr2_+_74153953 0.39 ENST00000264093.4
ENST00000348222.1
DGUOK
deoxyguanosine kinase
chr2_+_232575168 0.39 ENST00000440384.1
PTMA
prothymosin, alpha
chr1_-_208417620 0.39 ENST00000367033.3
PLXNA2
plexin A2
chr22_-_38349552 0.39 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
C22orf23
chromosome 22 open reading frame 23
chr16_-_66959429 0.38 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr19_+_50094866 0.38 ENST00000418929.2
PRR12
proline rich 12
chr8_+_128427857 0.38 ENST00000391675.1
POU5F1B
POU class 5 homeobox 1B
chr21_+_42741979 0.38 ENST00000543692.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr9_+_140145713 0.38 ENST00000388931.3
ENST00000412566.1
C9orf173
chromosome 9 open reading frame 173

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.6 1.8 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.5 1.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.4 1.7 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.4 1.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 2.4 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.3 0.9 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.3 8.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.3 1.8 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.3 0.8 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 0.7 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 0.5 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.2 1.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 0.7 GO:0044209 AMP salvage(GO:0044209)
0.2 1.0 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.2 0.7 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.5 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2 0.5 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.2 0.7 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 0.8 GO:0032218 riboflavin transport(GO:0032218)
0.2 0.8 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.1 3.4 GO:0007620 copulation(GO:0007620)
0.1 1.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.7 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.4 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.7 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.4 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.4 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 1.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.3 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 1.5 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.8 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.6 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.6 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.5 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.2 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 2.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.1 0.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:0035690 cellular response to drug(GO:0035690)
0.1 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.1 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 1.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.5 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.8 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.3 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.5 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.5 GO:0032328 alanine transport(GO:0032328) D-amino acid transport(GO:0042940)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.4 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 3.7 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 1.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.4 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.6 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 2.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.6 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.6 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.3 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 1.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.8 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 1.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0023035 CD40 signaling pathway(GO:0023035) protein linear polyubiquitination(GO:0097039)
0.0 0.4 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 1.0 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.5 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 1.5 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 1.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0007351 blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.0 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.7 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.2 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.0 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.5 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.7 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0008537 proteasome activator complex(GO:0008537)
0.4 1.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 0.8 GO:0036117 hyaluranon cable(GO:0036117)
0.2 0.5 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 1.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.6 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 3.2 GO:0005605 basal lamina(GO:0005605)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 5.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 3.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 1.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 2.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 2.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0043194 node of Ranvier(GO:0033268) axon initial segment(GO:0043194)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 3.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 1.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 1.0 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.3 1.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 3.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.2 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.2 0.9 GO:0047708 biotinidase activity(GO:0047708)
0.2 0.9 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 1.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.7 GO:0002060 purine nucleobase binding(GO:0002060)
0.2 1.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 0.8 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.6 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 2.0 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 2.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.3 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.6 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.5 GO:0070026 nitric oxide binding(GO:0070026)
0.1 0.9 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.1 0.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.2 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 1.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.4 GO:0035198 miRNA binding(GO:0035198)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.6 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 2.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.6 GO:0008483 transaminase activity(GO:0008483)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 3.8 GO:0005506 iron ion binding(GO:0005506)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.0 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 3.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 2.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.3 ST GAQ PATHWAY G alpha q Pathway
0.0 1.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 3.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.8 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.0 1.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi