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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX2-1

Z-value: 0.99

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Transcription factors associated with NKX2-1

Gene Symbol Gene ID Gene Info
NKX2-1
ENSG00000136352.13 NK2 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-1hg19_v2_chr14_-_36990354_36990397-0.907.3e-08Click!

Activity profile of NKX2-1 motif

Sorted Z-values of NKX2-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153518270 3.53 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chrX_-_30326445 3.10 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr1_-_153517473 2.78 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr22_+_24999114 2.34 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr8_-_38326119 2.24 ENST00000356207.5
ENST00000326324.6
FGFR1
fibroblast growth factor receptor 1
chr22_-_30968839 2.15 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr20_-_22565101 2.05 ENST00000419308.2
FOXA2
forkhead box A2
chr5_-_172662303 1.99 ENST00000517440.1
ENST00000329198.4
NKX2-5
NK2 homeobox 5
chr9_-_4299874 1.97 ENST00000381971.3
ENST00000477901.1
GLIS3
GLIS family zinc finger 3
chr5_-_58335281 1.86 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_+_73642315 1.80 ENST00000556126.2
SMIM6
small integral membrane protein 6
chr5_-_58571935 1.76 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr22_-_30968813 1.76 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr17_+_73642486 1.71 ENST00000579469.1
SMIM6
small integral membrane protein 6
chr17_+_76210267 1.68 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr17_+_26646121 1.65 ENST00000226230.6
TMEM97
transmembrane protein 97
chr2_+_101591314 1.62 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr17_+_4613918 1.49 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2
arrestin, beta 2
chr2_-_175870085 1.45 ENST00000409156.3
CHN1
chimerin 1
chr17_+_26646175 1.43 ENST00000583381.1
ENST00000582113.1
ENST00000582384.1
TMEM97
transmembrane protein 97
chr5_+_140345820 1.40 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr15_+_76030311 1.39 ENST00000543887.1
AC019294.1
AC019294.1
chr19_+_39390320 1.36 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr15_+_40453204 1.35 ENST00000287598.6
ENST00000412359.3
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chr16_+_66638003 1.33 ENST00000562357.1
ENST00000360086.4
ENST00000562707.1
ENST00000361909.4
ENST00000460097.1
ENST00000565666.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr5_-_172662230 1.29 ENST00000424406.2
NKX2-5
NK2 homeobox 5
chr2_-_133429091 1.28 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr11_-_86383650 1.24 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr5_-_172662197 1.19 ENST00000521848.1
NKX2-5
NK2 homeobox 5
chr17_+_76210367 1.18 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr12_+_121416489 1.15 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr8_+_62200509 1.14 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr10_-_14596140 1.10 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr18_+_3450161 1.09 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr16_+_57126428 1.07 ENST00000290776.8
CPNE2
copine II
chr21_+_45773515 1.06 ENST00000397932.2
ENST00000300481.9
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr7_-_95064264 1.05 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2
paraoxonase 2
chr19_+_36235964 1.01 ENST00000587708.2
PSENEN
presenilin enhancer gamma secretase subunit
chr16_+_57126482 1.01 ENST00000537605.1
ENST00000535318.2
CPNE2
copine II
chr6_-_42858534 0.99 ENST00000408925.2
C6orf226
chromosome 6 open reading frame 226
chr8_-_62602327 0.99 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr17_-_42466864 0.99 ENST00000353281.4
ENST00000262407.5
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chrX_-_119693745 0.97 ENST00000371323.2
CUL4B
cullin 4B
chr12_-_102591604 0.97 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr1_-_41487383 0.97 ENST00000302946.8
ENST00000372613.2
ENST00000439569.2
ENST00000397197.2
SLFNL1
schlafen-like 1
chr16_+_5121814 0.94 ENST00000262374.5
ENST00000586840.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr2_-_157189180 0.93 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr7_+_99156249 0.90 ENST00000449244.1
ZNF655
zinc finger protein 655
chr7_+_150758642 0.87 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr14_-_58893876 0.85 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr16_+_66638616 0.83 ENST00000564060.1
ENST00000565922.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr8_-_144679602 0.82 ENST00000526710.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr8_+_37654693 0.81 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr19_-_36231437 0.79 ENST00000591748.1
IGFLR1
IGF-like family receptor 1
chr6_+_100054606 0.77 ENST00000369215.4
PRDM13
PR domain containing 13
chrX_-_83442915 0.76 ENST00000262752.2
ENST00000543399.1
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr19_+_40477062 0.76 ENST00000455878.2
PSMC4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr10_-_79397547 0.74 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_11685345 0.74 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr9_-_97356075 0.74 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr19_+_24009879 0.73 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr16_+_58533951 0.73 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr7_+_99156212 0.71 ENST00000454654.1
ZNF655
zinc finger protein 655
chr19_-_45748628 0.69 ENST00000590022.1
AC006126.4
AC006126.4
chr16_+_640055 0.69 ENST00000568586.1
ENST00000538492.1
ENST00000248139.3
RAB40C
RAB40C, member RAS oncogene family
chr16_+_66638567 0.68 ENST00000567572.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chrX_-_70474499 0.67 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr19_+_50148087 0.67 ENST00000601038.1
ENST00000595242.1
SCAF1
SR-related CTD-associated factor 1
chr3_-_114790179 0.66 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_25291475 0.65 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr17_+_46048497 0.64 ENST00000583352.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr20_-_36793663 0.62 ENST00000536701.1
ENST00000536724.1
TGM2
transglutaminase 2
chr17_-_8198636 0.60 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr17_-_60005329 0.59 ENST00000251334.6
INTS2
integrator complex subunit 2
chr15_+_69452959 0.59 ENST00000261858.2
GLCE
glucuronic acid epimerase
chr17_-_47492236 0.58 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin
chr7_-_121944491 0.55 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr16_+_28303804 0.54 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chrX_-_70474377 0.54 ENST00000373978.1
ENST00000373981.1
ZMYM3
zinc finger, MYM-type 3
chr17_-_60005365 0.54 ENST00000444766.3
INTS2
integrator complex subunit 2
chr8_+_94752349 0.53 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr19_-_46234119 0.51 ENST00000317683.3
FBXO46
F-box protein 46
chrX_-_70473957 0.50 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3
zinc finger, MYM-type 3
chr2_+_99797636 0.50 ENST00000409145.1
MRPL30
mitochondrial ribosomal protein L30
chr19_+_751122 0.50 ENST00000215582.6
MISP
mitotic spindle positioning
chr1_+_15736359 0.50 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr17_-_79623597 0.49 ENST00000574024.1
ENST00000331056.5
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr16_+_71929397 0.47 ENST00000537613.1
ENST00000424485.2
ENST00000606369.1
ENST00000329908.8
ENST00000538850.1
ENST00000541918.1
ENST00000534994.1
ENST00000378798.5
ENST00000539186.1
IST1
increased sodium tolerance 1 homolog (yeast)
chr19_+_48958766 0.47 ENST00000342291.2
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr16_-_67190152 0.47 ENST00000486556.1
TRADD
TNFRSF1A-associated via death domain
chr3_-_49837254 0.46 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
CDHR4
cadherin-related family member 4
chr12_-_21810765 0.46 ENST00000450584.1
ENST00000350669.1
LDHB
lactate dehydrogenase B
chr12_-_10978957 0.46 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr1_+_228337553 0.45 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr14_-_58893832 0.45 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_-_41487415 0.45 ENST00000372611.1
SLFNL1
schlafen-like 1
chr20_-_35724388 0.45 ENST00000344359.3
ENST00000373664.3
RBL1
retinoblastoma-like 1 (p107)
chr2_-_25451065 0.43 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr14_+_74353320 0.43 ENST00000540593.1
ENST00000555730.1
ZNF410
zinc finger protein 410
chr12_-_21810726 0.43 ENST00000396076.1
LDHB
lactate dehydrogenase B
chr19_-_38720354 0.42 ENST00000416611.1
DPF1
D4, zinc and double PHD fingers family 1
chr20_-_56285595 0.42 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr15_-_66790146 0.42 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr20_+_30407151 0.42 ENST00000375985.4
MYLK2
myosin light chain kinase 2
chr12_+_50479101 0.41 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr20_+_30407105 0.41 ENST00000375994.2
MYLK2
myosin light chain kinase 2
chr10_-_103454876 0.41 ENST00000331272.7
FBXW4
F-box and WD repeat domain containing 4
chr17_-_47492164 0.40 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
PHB
prohibitin
chr10_-_98347063 0.40 ENST00000443638.1
TM9SF3
transmembrane 9 superfamily member 3
chr17_+_59529743 0.39 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr5_+_131705438 0.39 ENST00000245407.3
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr2_+_152266604 0.38 ENST00000430328.2
RIF1
RAP1 interacting factor homolog (yeast)
chr1_+_170115142 0.37 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr21_+_33671264 0.37 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr12_+_50478977 0.37 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr11_-_65325203 0.36 ENST00000526927.1
ENST00000536982.1
LTBP3
latent transforming growth factor beta binding protein 3
chr6_-_26056695 0.36 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr16_+_2022036 0.35 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr15_-_94614049 0.35 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr1_-_153599426 0.34 ENST00000392622.1
S100A13
S100 calcium binding protein A13
chr17_+_46048376 0.34 ENST00000338399.4
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr9_-_128246769 0.34 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr1_+_206643787 0.34 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr12_+_50479109 0.33 ENST00000550477.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr11_-_65325430 0.32 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr1_-_115259337 0.32 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr5_-_146889619 0.31 ENST00000343218.5
DPYSL3
dihydropyrimidinase-like 3
chr12_-_719573 0.31 ENST00000397265.3
NINJ2
ninjurin 2
chr11_+_105948216 0.30 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr7_+_99156145 0.30 ENST00000452314.1
ENST00000252713.4
ZNF655
zinc finger protein 655
chr17_+_26684604 0.30 ENST00000292114.3
ENST00000509083.1
TMEM199
transmembrane protein 199
chrX_-_108976449 0.29 ENST00000469857.1
ACSL4
acyl-CoA synthetase long-chain family member 4
chr6_-_27841289 0.29 ENST00000355981.2
HIST1H4L
histone cluster 1, H4l
chr3_+_19189946 0.28 ENST00000328405.2
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr8_-_16859690 0.27 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr14_+_67708344 0.27 ENST00000557237.1
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr17_-_34195862 0.26 ENST00000592980.1
ENST00000587626.1
C17orf66
chromosome 17 open reading frame 66
chrX_+_78003204 0.25 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr15_+_89182156 0.24 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_-_34195889 0.24 ENST00000311880.2
C17orf66
chromosome 17 open reading frame 66
chr1_+_207277590 0.23 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chrX_-_110655306 0.23 ENST00000371993.2
DCX
doublecortin
chr18_+_56806701 0.23 ENST00000587834.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr2_+_85646054 0.22 ENST00000389938.2
SH2D6
SH2 domain containing 6
chrX_-_134478012 0.22 ENST00000370766.3
ZNF75D
zinc finger protein 75D
chr10_+_80027105 0.21 ENST00000461034.1
ENST00000476909.1
ENST00000459633.1
LINC00595
long intergenic non-protein coding RNA 595
chr9_-_5830768 0.20 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr2_-_152118352 0.20 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr2_-_225266711 0.19 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr15_-_33360085 0.19 ENST00000334528.9
FMN1
formin 1
chr9_-_72374848 0.19 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr2_-_225266802 0.19 ENST00000243806.2
FAM124B
family with sequence similarity 124B
chr17_-_49198216 0.18 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr2_-_180610767 0.18 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr16_-_28223166 0.18 ENST00000304658.5
XPO6
exportin 6
chr4_-_79860506 0.17 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chrX_-_153236819 0.17 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr17_+_46048471 0.17 ENST00000578018.1
ENST00000579175.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr7_-_27224795 0.16 ENST00000006015.3
HOXA11
homeobox A11
chr6_+_31554779 0.16 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr18_-_10791648 0.16 ENST00000583325.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr2_-_176032843 0.16 ENST00000392544.1
ENST00000409499.1
ENST00000426833.3
ENST00000392543.2
ENST00000538946.1
ENST00000487334.2
ENST00000409833.1
ENST00000409635.1
ENST00000264110.2
ENST00000345739.5
ATF2
activating transcription factor 2
chr18_+_29171689 0.15 ENST00000237014.3
TTR
transthyretin
chr1_-_236445251 0.15 ENST00000354619.5
ENST00000327333.8
ERO1LB
ERO1-like beta (S. cerevisiae)
chr8_+_22019168 0.15 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
SFTPC
surfactant protein C
chr2_+_99797542 0.15 ENST00000338148.3
ENST00000512183.2
MRPL30
C2orf15
mitochondrial ribosomal protein L30
chromosome 2 open reading frame 15
chr6_-_71012773 0.14 ENST00000370496.3
ENST00000357250.6
COL9A1
collagen, type IX, alpha 1
chrX_+_86772707 0.14 ENST00000373119.4
KLHL4
kelch-like family member 4
chr1_+_66999268 0.13 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr15_+_57511609 0.13 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr17_-_3499125 0.13 ENST00000399759.3
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr2_+_220379052 0.13 ENST00000347842.3
ENST00000358078.4
ASIC4
acid-sensing (proton-gated) ion channel family member 4
chr4_+_184826418 0.13 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr11_-_105948129 0.13 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chrX_-_108976410 0.13 ENST00000504980.1
ACSL4
acyl-CoA synthetase long-chain family member 4
chr3_+_187930491 0.13 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr10_-_98031155 0.12 ENST00000495266.1
BLNK
B-cell linker
chr10_+_102222798 0.12 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr10_-_81320151 0.12 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
SFTPA2
surfactant protein A2
chr3_+_4535155 0.12 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr3_-_42744312 0.11 ENST00000416756.1
ENST00000441594.1
HHATL
hedgehog acyltransferase-like
chr8_+_77596014 0.11 ENST00000523885.1
ZFHX4
zinc finger homeobox 4
chr6_-_149806105 0.11 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D
zinc finger CCCH-type containing 12D
chr10_-_7708918 0.11 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr18_-_24283586 0.11 ENST00000579458.1
U3
Small nucleolar RNA U3
chr6_-_55740352 0.10 ENST00000370830.3
BMP5
bone morphogenetic protein 5
chr7_-_27224842 0.10 ENST00000517402.1
HOXA11
homeobox A11
chr19_+_48972265 0.10 ENST00000452733.2
CYTH2
cytohesin 2
chr2_-_225266743 0.10 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr14_+_74815116 0.10 ENST00000256362.4
VRTN
vertebrae development associated
chr15_-_43029252 0.09 ENST00000563260.1
ENST00000356231.3
CDAN1
codanin 1
chr16_-_67493110 0.08 ENST00000602876.1
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr8_-_144679296 0.08 ENST00000317198.6
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chrX_+_86772787 0.08 ENST00000373114.4
KLHL4
kelch-like family member 4
chr18_+_13382553 0.08 ENST00000586222.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr19_+_1065922 0.07 ENST00000539243.2
HMHA1
histocompatibility (minor) HA-1
chr3_-_52029958 0.07 ENST00000294189.6
RPL29
ribosomal protein L29
chr6_+_25652501 0.07 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chr17_+_61571746 0.07 ENST00000579409.1
ACE
angiotensin I converting enzyme
chr17_+_59489112 0.06 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0060929 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.7 2.2 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.5 2.0 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 1.1 GO:0035623 renal glucose absorption(GO:0035623)
0.4 3.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 1.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3 0.9 GO:0051866 general adaptation syndrome(GO:0051866)
0.3 3.9 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 1.5 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.2 1.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 2.3 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.2 0.7 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 3.1 GO:0030238 male sex determination(GO:0030238)
0.2 1.0 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 2.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 0.6 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 2.9 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.8 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 1.1 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.7 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 1.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 1.2 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.4 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.8 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.7 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 1.3 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.9 GO:0006089 lactate metabolic process(GO:0006089)
0.0 1.0 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.5 GO:0009838 abscission(GO:0009838)
0.0 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0021502 neural fold elevation formation(GO:0021502) allantois development(GO:1905069)
0.0 0.1 GO:0060262 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.3 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.7 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.5 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.3 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 3.1 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 1.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 1.6 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.6 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 5.0 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 2.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 GO:0098589 membrane region(GO:0098589)
0.4 2.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 1.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.2 3.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.4 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 0.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 3.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 3.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 5.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.4 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0010736 serum response element binding(GO:0010736)
0.5 1.5 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.4 1.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.3 1.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.3 3.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 1.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 6.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 1.0 GO:0070051 fibrinogen binding(GO:0070051)
0.2 2.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.7 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 1.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 3.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 1.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 0.5 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 2.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 3.1 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 0.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.4 GO:0036435 IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.1 0.4 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 3.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.5 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 1.2 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 2.9 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.9 PID AURORA A PATHWAY Aurora A signaling
0.0 2.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 3.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 4.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 2.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter