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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX2-4

Z-value: 0.65

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Transcription factors associated with NKX2-4

Gene Symbol Gene ID Gene Info
NKX2-4
ENSG00000125816.4 NK2 homeobox 4

Activity profile of NKX2-4 motif

Sorted Z-values of NKX2-4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_129932974 1.04 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4
carboxypeptidase A4
chr2_+_109065634 1.02 ENST00000409821.1
GCC2
GRIP and coiled-coil domain containing 2
chr10_+_6821545 0.85 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr2_+_201677390 0.85 ENST00000447069.1
BZW1
basic leucine zipper and W2 domains 1
chr5_+_147443534 0.85 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr7_-_80551671 0.80 ENST00000419255.2
ENST00000544525.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_+_222886694 0.77 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr6_-_56492816 0.71 ENST00000522360.1
DST
dystonin
chr18_-_28622699 0.70 ENST00000360428.4
DSC3
desmocollin 3
chr1_-_115301235 0.69 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr18_-_28622774 0.68 ENST00000434452.1
DSC3
desmocollin 3
chr5_-_78808617 0.67 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chrX_-_138914394 0.62 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr17_-_40264692 0.60 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_-_85780853 0.60 ENST00000531930.1
ENST00000528398.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr1_-_222886526 0.58 ENST00000541237.1
AIDA
axin interactor, dorsalization associated
chr10_-_91102410 0.57 ENST00000282673.4
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr10_+_98592674 0.55 ENST00000356016.3
ENST00000371097.4
LCOR
ligand dependent nuclear receptor corepressor
chr4_-_103746683 0.54 ENST00000504211.1
ENST00000508476.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_+_152974218 0.53 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
SPRR3
small proline-rich protein 3
chr1_-_224624730 0.52 ENST00000445239.1
WDR26
WD repeat domain 26
chrX_-_30993201 0.51 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr13_-_52026730 0.51 ENST00000420668.2
INTS6
integrator complex subunit 6
chr21_+_38792602 0.51 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr21_-_16374688 0.50 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr18_-_33702078 0.49 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr2_-_225434538 0.48 ENST00000409096.1
CUL3
cullin 3
chr11_+_34642656 0.48 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr6_-_131277510 0.48 ENST00000525193.1
ENST00000527659.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr16_+_1730338 0.47 ENST00000566691.1
ENST00000382710.4
HN1L
hematological and neurological expressed 1-like
chr14_+_51955831 0.47 ENST00000356218.4
FRMD6
FERM domain containing 6
chr18_-_44500101 0.46 ENST00000589917.1
ENST00000587810.1
PIAS2
protein inhibitor of activated STAT, 2
chr9_+_128510454 0.45 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chr12_-_122884553 0.45 ENST00000535290.1
CLIP1
CAP-GLY domain containing linker protein 1
chr11_-_119993979 0.45 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chr12_-_48500085 0.45 ENST00000549518.1
SENP1
SUMO1/sentrin specific peptidase 1
chr7_+_106810165 0.45 ENST00000468401.1
ENST00000497535.1
ENST00000485846.1
HBP1
HMG-box transcription factor 1
chr11_-_105892937 0.44 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr8_+_22844995 0.44 ENST00000524077.1
RHOBTB2
Rho-related BTB domain containing 2
chr17_+_66244071 0.44 ENST00000580548.1
ENST00000580753.1
ENST00000392720.2
ENST00000359783.4
ENST00000584837.1
ENST00000579724.1
ENST00000584494.1
ENST00000580837.1
AMZ2
archaelysin family metallopeptidase 2
chr7_+_116139424 0.43 ENST00000222693.4
CAV2
caveolin 2
chr3_-_56950407 0.43 ENST00000496106.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr6_+_106988986 0.43 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr5_+_154135453 0.43 ENST00000517616.1
ENST00000518892.1
LARP1
La ribonucleoprotein domain family, member 1
chr5_+_154135029 0.42 ENST00000518297.1
LARP1
La ribonucleoprotein domain family, member 1
chr4_-_103747011 0.42 ENST00000350435.7
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_94147385 0.42 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr12_+_10658201 0.42 ENST00000322446.3
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr1_-_161059380 0.41 ENST00000368012.3
PVRL4
poliovirus receptor-related 4
chr11_-_14521349 0.41 ENST00000534234.1
COPB1
coatomer protein complex, subunit beta 1
chr12_+_123237321 0.40 ENST00000280557.6
ENST00000455982.2
DENR
density-regulated protein
chr14_-_104028595 0.40 ENST00000337322.4
ENST00000445922.2
BAG5
BCL2-associated athanogene 5
chr3_+_189349162 0.39 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr19_-_41942344 0.39 ENST00000594660.1
ATP5SL
ATP5S-like
chr4_-_103746924 0.39 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr10_-_28571015 0.39 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr8_-_49833978 0.39 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr3_-_69249863 0.39 ENST00000478263.1
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr10_-_94301107 0.39 ENST00000436178.1
IDE
insulin-degrading enzyme
chr6_-_28303901 0.39 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr19_+_10765614 0.39 ENST00000589283.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr2_+_172309634 0.38 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr15_+_80364901 0.38 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr1_+_15986364 0.38 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr2_-_37899323 0.38 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr21_+_40177143 0.38 ENST00000360214.3
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr7_+_36450169 0.38 ENST00000428612.1
ANLN
anillin, actin binding protein
chr14_-_81408093 0.38 ENST00000555265.1
CEP128
centrosomal protein 128kDa
chr12_+_8975061 0.37 ENST00000299698.7
A2ML1
alpha-2-macroglobulin-like 1
chr15_-_78358465 0.36 ENST00000435468.1
TBC1D2B
TBC1 domain family, member 2B
chr5_-_98262240 0.36 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr4_+_75480629 0.36 ENST00000380846.3
AREGB
amphiregulin B
chr19_-_55767125 0.35 ENST00000592242.1
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr11_-_85779971 0.35 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr10_+_60094735 0.35 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr4_-_68411275 0.35 ENST00000273853.6
CENPC
centromere protein C
chr4_+_26578293 0.34 ENST00000512840.1
TBC1D19
TBC1 domain family, member 19
chr1_+_145575227 0.34 ENST00000393046.2
ENST00000369299.3
ENST00000463514.2
PIAS3
protein inhibitor of activated STAT, 3
chr8_-_141774467 0.34 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr1_-_70671216 0.34 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr10_-_65225641 0.34 ENST00000399262.2
JMJD1C
jumonji domain containing 1C
chr10_+_99332529 0.33 ENST00000455090.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr11_+_3875757 0.33 ENST00000525403.1
STIM1
stromal interaction molecule 1
chr13_-_36944307 0.33 ENST00000355182.4
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr11_-_61124776 0.33 ENST00000542361.1
CYB561A3
cytochrome b561 family, member A3
chr17_-_38574169 0.32 ENST00000423485.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr22_+_25465786 0.32 ENST00000401395.1
KIAA1671
KIAA1671
chr14_-_81893734 0.32 ENST00000555447.1
STON2
stonin 2
chr2_+_105953972 0.31 ENST00000410049.1
C2orf49
chromosome 2 open reading frame 49
chr8_+_22844913 0.31 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr14_+_56078695 0.31 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr5_-_39270725 0.31 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr4_+_90033968 0.31 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr7_+_107384142 0.30 ENST00000440859.3
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr10_-_65225722 0.30 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chr6_-_136610911 0.30 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1
BCL2-associated transcription factor 1
chr2_-_37501692 0.30 ENST00000443977.1
PRKD3
protein kinase D3
chr9_+_131445928 0.30 ENST00000372692.4
SET
SET nuclear oncogene
chr1_-_89458287 0.30 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr1_+_110036699 0.30 ENST00000496961.1
ENST00000533024.1
ENST00000310611.4
ENST00000527072.1
ENST00000420578.2
ENST00000528785.1
CYB561D1
cytochrome b561 family, member D1
chr2_-_166651152 0.29 ENST00000431484.1
ENST00000412248.1
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr16_+_68729719 0.29 ENST00000569080.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr17_+_61151306 0.29 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_-_80994619 0.29 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr5_+_64064748 0.29 ENST00000381070.3
ENST00000508024.1
CWC27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr19_+_59055412 0.29 ENST00000593582.1
TRIM28
tripartite motif containing 28
chr15_-_43398274 0.29 ENST00000382177.2
ENST00000290650.4
UBR1
ubiquitin protein ligase E3 component n-recognin 1
chr16_+_81070792 0.29 ENST00000564241.1
ENST00000565237.1
ATMIN
ATM interactor
chr7_-_92463210 0.29 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr1_+_32042105 0.29 ENST00000457433.2
ENST00000441210.2
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr11_+_107992518 0.29 ENST00000527942.1
ACAT1
acetyl-CoA acetyltransferase 1
chr8_-_141728444 0.28 ENST00000521562.1
PTK2
protein tyrosine kinase 2
chr1_+_95583479 0.28 ENST00000455656.1
ENST00000604534.1
TMEM56
RP11-57H12.6
transmembrane protein 56
TMEM56-RWDD3 readthrough
chr2_-_166651191 0.28 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr11_+_12766583 0.28 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr18_-_21852143 0.28 ENST00000399443.3
OSBPL1A
oxysterol binding protein-like 1A
chr6_-_30899924 0.28 ENST00000359086.3
SFTA2
surfactant associated 2
chr1_+_64239657 0.27 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr3_+_30647994 0.27 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr6_-_152958521 0.27 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr12_-_123011476 0.26 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr3_+_118905564 0.26 ENST00000460625.1
UPK1B
uroplakin 1B
chr6_-_149969871 0.26 ENST00000335643.8
ENST00000444282.1
KATNA1
katanin p60 (ATPase containing) subunit A 1
chr11_+_34645791 0.25 ENST00000529527.1
ENST00000531728.1
ENST00000525253.1
EHF
ets homologous factor
chr2_-_220025263 0.25 ENST00000457600.1
NHEJ1
nonhomologous end-joining factor 1
chr15_+_44719996 0.25 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr8_+_67687773 0.25 ENST00000518388.1
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr1_+_110036674 0.25 ENST00000393709.3
CYB561D1
cytochrome b561 family, member D1
chr19_-_11688500 0.25 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr3_+_15045419 0.25 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr7_-_17980091 0.25 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr1_-_243349684 0.25 ENST00000522895.1
CEP170
centrosomal protein 170kDa
chr7_+_151038850 0.24 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr18_+_72166564 0.24 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr4_-_68749745 0.24 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr18_+_21032781 0.24 ENST00000339486.3
RIOK3
RIO kinase 3
chr2_+_38177575 0.24 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr17_+_75277492 0.24 ENST00000427177.1
ENST00000591198.1
SEPT9
septin 9
chr2_+_53994927 0.24 ENST00000295304.4
CHAC2
ChaC, cation transport regulator homolog 2 (E. coli)
chr5_-_34919094 0.24 ENST00000341754.4
RAD1
RAD1 homolog (S. pombe)
chrX_-_54069576 0.23 ENST00000445025.1
ENST00000322659.8
PHF8
PHD finger protein 8
chr17_-_42976985 0.23 ENST00000426333.2
EFTUD2
elongation factor Tu GTP binding domain containing 2
chr2_+_205410723 0.23 ENST00000358768.2
ENST00000351153.1
ENST00000349953.3
PARD3B
par-3 family cell polarity regulator beta
chr12_+_21590549 0.23 ENST00000545178.1
ENST00000240651.9
PYROXD1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr2_+_161993465 0.23 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr13_-_108867846 0.22 ENST00000442234.1
LIG4
ligase IV, DNA, ATP-dependent
chr1_-_85870177 0.22 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr5_+_159436120 0.22 ENST00000522793.1
ENST00000231238.5
TTC1
tetratricopeptide repeat domain 1
chr4_-_185726906 0.22 ENST00000513317.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr7_-_104909435 0.22 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr5_+_118788433 0.22 ENST00000414835.2
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr4_-_68749699 0.22 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr12_-_39837192 0.22 ENST00000361961.3
ENST00000395670.3
KIF21A
kinesin family member 21A
chr11_-_19263145 0.22 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr12_+_133757995 0.22 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268
zinc finger protein 268
chr1_-_160231451 0.21 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr2_+_219110149 0.21 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr17_-_42976736 0.21 ENST00000591382.1
ENST00000593072.1
ENST00000592576.1
ENST00000402521.3
EFTUD2
elongation factor Tu GTP binding domain containing 2
chr8_-_141810634 0.21 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr21_-_45078019 0.21 ENST00000542962.1
HSF2BP
heat shock transcription factor 2 binding protein
chr6_+_35265586 0.21 ENST00000542066.1
ENST00000316637.5
DEF6
differentially expressed in FDCP 6 homolog (mouse)
chr17_+_46918925 0.21 ENST00000502761.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr19_+_10765699 0.21 ENST00000590009.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr17_+_41561317 0.21 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr4_-_87028478 0.21 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr5_-_94417339 0.21 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr19_-_12444306 0.21 ENST00000594577.1
ENST00000601858.1
ZNF563
zinc finger protein 563
chr6_+_45390222 0.21 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr14_+_45431379 0.20 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B
family with sequence similarity 179, member B
chr18_+_55816546 0.20 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr2_+_183982238 0.20 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
NUP35
nucleoporin 35kDa
chr22_-_26961328 0.20 ENST00000398110.2
TPST2
tyrosylprotein sulfotransferase 2
chr16_-_82045049 0.20 ENST00000532128.1
ENST00000328945.5
SDR42E1
short chain dehydrogenase/reductase family 42E, member 1
chr1_-_197744763 0.20 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chr2_-_37544209 0.20 ENST00000234179.2
PRKD3
protein kinase D3
chr2_-_3521518 0.20 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr19_-_12444519 0.20 ENST00000595977.1
ZNF563
zinc finger protein 563
chr18_-_29340827 0.20 ENST00000269205.5
SLC25A52
solute carrier family 25, member 52
chr2_+_159825143 0.20 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr17_+_28804380 0.20 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr14_+_96829886 0.20 ENST00000556095.1
GSKIP
GSK3B interacting protein
chr1_-_42801540 0.20 ENST00000372573.1
FOXJ3
forkhead box J3
chr14_-_88459182 0.20 ENST00000544807.2
GALC
galactosylceramidase
chr19_-_49258606 0.20 ENST00000310160.3
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr13_-_108870623 0.19 ENST00000405925.1
LIG4
ligase IV, DNA, ATP-dependent
chr7_+_65552756 0.19 ENST00000450043.1
AC068533.7
AC068533.7
chr11_-_10715287 0.19 ENST00000423302.2
MRVI1
murine retrovirus integration site 1 homolog
chr2_-_179315786 0.19 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr20_-_39928756 0.19 ENST00000432768.2
ZHX3
zinc fingers and homeoboxes 3
chr16_+_58010339 0.19 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chr19_-_20748541 0.19 ENST00000427401.4
ENST00000594419.1
ZNF737
zinc finger protein 737
chr8_+_41347915 0.19 ENST00000518270.1
ENST00000520817.1
GOLGA7
golgin A7
chr7_+_134551583 0.19 ENST00000435928.1
CALD1
caldesmon 1
chr9_-_36258326 0.19 ENST00000447283.2
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr19_-_20748614 0.19 ENST00000596797.1
ZNF737
zinc finger protein 737
chr6_+_26158343 0.19 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr3_+_141596371 0.19 ENST00000495216.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr8_+_37594103 0.19 ENST00000397228.2
ERLIN2
ER lipid raft associated 2
chr4_+_86749045 0.19 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr1_+_110036728 0.18 ENST00000369868.3
ENST00000430195.2
CYB561D1
cytochrome b561 family, member D1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 0.5 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 0.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 1.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 0.5 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.8 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.4 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.4 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.1 0.8 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.1 0.3 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.4 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.3 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.3 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.3 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.8 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.5 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.2 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.1 0.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.3 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:0039521 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.6 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.4 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.4 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation of dopamine receptor signaling pathway(GO:0060161) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.6 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 1.7 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.3 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:0042223 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.5 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.5 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.0 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.6 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.0 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.2 GO:0000052 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527) negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.0 GO:1902617 response to fluoride(GO:1902617)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.5 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.8 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 0.8 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.8 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 1.4 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.5 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.2 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.4 GO:0016248 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 0.2 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.2 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 1.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis