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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX2-6

Z-value: 0.68

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Transcription factors associated with NKX2-6

Gene Symbol Gene ID Gene Info
ENSG00000180053.6 NK2 homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-6hg19_v2_chr8_-_23563922_235641110.048.6e-01Click!

Activity profile of NKX2-6 motif

Sorted Z-values of NKX2-6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_120365866 2.21 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr12_+_56075330 1.94 ENST00000394252.3
methyltransferase like 7B
chr5_-_59481406 1.58 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr8_+_27629459 1.56 ENST00000523566.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr15_-_56757329 1.31 ENST00000260453.3
meiosis-specific nuclear structural 1
chr9_-_19065082 1.27 ENST00000415524.1
HAUS augmin-like complex, subunit 6
chr11_-_61687739 1.27 ENST00000531922.1
ENST00000301773.5
RAB3A interacting protein (rabin3)-like 1
chr7_-_107880508 1.16 ENST00000425651.2
neuronal cell adhesion molecule
chr9_+_97766409 1.11 ENST00000425634.2
chromosome 9 open reading frame 3
chr8_+_99076509 1.09 ENST00000318528.3
chromosome 8 open reading frame 47
chr1_-_36863481 1.05 ENST00000315732.2
LSM10, U7 small nuclear RNA associated
chr17_-_57229155 1.04 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr8_+_41386761 1.04 ENST00000523277.2
GINS complex subunit 4 (Sld5 homolog)
chr12_+_113354341 1.01 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr22_+_44427230 0.97 ENST00000444029.1
parvin, beta
chr8_-_95220775 0.97 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr20_-_32262165 0.96 ENST00000606690.1
ENST00000246190.6
ENST00000439478.1
ENST00000375238.4
N-terminal EF-hand calcium binding protein 3
chr12_-_8088773 0.94 ENST00000544291.1
solute carrier family 2 (facilitated glucose transporter), member 3
chr3_-_123339343 0.94 ENST00000578202.1
myosin light chain kinase
chr15_+_65843130 0.88 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr20_-_5100591 0.87 ENST00000379143.5
proliferating cell nuclear antigen
chr12_-_8088871 0.87 ENST00000075120.7
solute carrier family 2 (facilitated glucose transporter), member 3
chr8_+_42396712 0.81 ENST00000518574.1
ENST00000417410.2
ENST00000414154.2
small integral membrane protein 19
chr10_+_135204338 0.80 ENST00000468317.2
Mitochondrial GTPase 1
chr17_-_34890037 0.80 ENST00000589404.1
myosin XIX
chr17_-_39341594 0.78 ENST00000398472.1
keratin associated protein 4-1
chr17_+_49337881 0.76 ENST00000225298.7
UTP18 small subunit (SSU) processome component homolog (yeast)
chr2_-_121624973 0.75 ENST00000603720.1
RP11-297J22.1
chr20_-_271009 0.70 ENST00000382369.5
chromosome 20 open reading frame 96
chr3_-_123339418 0.69 ENST00000583087.1
myosin light chain kinase
chr3_+_37035289 0.68 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
mutL homolog 1
chr17_-_34890665 0.68 ENST00000586007.1
myosin XIX
chr11_+_65627974 0.67 ENST00000525768.1
MUS81 structure-specific endonuclease subunit
chr7_-_56101826 0.66 ENST00000421626.1
phosphoserine phosphatase
chr11_+_118958689 0.66 ENST00000535253.1
ENST00000392841.1
hydroxymethylbilane synthase
chr3_-_127541194 0.64 ENST00000453507.2
monoglyceride lipase
chr19_-_51611623 0.63 ENST00000421832.2
cytosolic thiouridylase subunit 1
chr17_-_44896047 0.61 ENST00000225512.5
wingless-type MMTV integration site family, member 3
chr2_+_87769459 0.60 ENST00000414030.1
ENST00000437561.1
long intergenic non-protein coding RNA 152
chr15_+_84841242 0.60 ENST00000558195.1
ubiquitin-conjugating enzyme E2Q family member 2-like
chr17_-_34890617 0.59 ENST00000586886.1
ENST00000585719.1
ENST00000585818.1
myosin XIX
chr6_+_126102292 0.57 ENST00000368357.3
nuclear receptor coactivator 7
chr17_+_33914276 0.57 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr17_-_34890709 0.56 ENST00000544606.1
myosin XIX
chr12_-_89919965 0.56 ENST00000548729.1
POC1B-GALNT4 readthrough
chr19_-_49552363 0.56 ENST00000448456.3
ENST00000355414.2
chorionic gonadotropin, beta polypeptide 8
chr7_-_37382360 0.55 ENST00000455119.1
engulfment and cell motility 1
chr8_+_42396936 0.55 ENST00000416469.2
small integral membrane protein 19
chr18_+_68002675 0.55 ENST00000584919.1
Uncharacterized protein
chr19_-_49843539 0.55 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
chr15_-_72668805 0.54 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr11_-_118901559 0.54 ENST00000330775.7
ENST00000545985.1
ENST00000357590.5
ENST00000538950.1
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chrX_-_53310791 0.54 ENST00000375365.2
IQ motif and Sec7 domain 2
chr8_-_62602327 0.53 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
aspartate beta-hydroxylase
chr3_-_157824292 0.52 ENST00000483851.2
short stature homeobox 2
chr17_+_33914460 0.51 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr10_-_27529486 0.50 ENST00000375888.1
acyl-CoA binding domain containing 5
chr16_-_69373396 0.50 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
component of oligomeric golgi complex 8
chr17_+_41150290 0.50 ENST00000589037.1
ENST00000253788.5
ribosomal protein L27
chr12_-_89920030 0.50 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr3_-_114790179 0.50 ENST00000462705.1
zinc finger and BTB domain containing 20
chr21_-_46964306 0.50 ENST00000443742.1
ENST00000528477.1
ENST00000567670.1
solute carrier family 19 (folate transporter), member 1
chr17_-_62493131 0.49 ENST00000539111.2
polymerase (DNA directed), gamma 2, accessory subunit
chr14_-_30766223 0.48 ENST00000549360.1
ENST00000508469.2
CTD-2251F13.1
chr7_-_150777874 0.47 ENST00000540185.1
Fas-activated serine/threonine kinase
chr7_-_150777920 0.47 ENST00000353841.2
ENST00000297532.6
Fas-activated serine/threonine kinase
chr8_+_22414182 0.47 ENST00000524057.1
sorbin and SH3 domain containing 3
chr10_-_13342097 0.46 ENST00000263038.4
phytanoyl-CoA 2-hydroxylase
chr14_+_50779029 0.46 ENST00000245448.6
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr2_-_175462934 0.46 ENST00000392546.2
ENST00000436221.1
WAS/WASL interacting protein family, member 1
chr15_-_55563072 0.46 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr12_-_89919765 0.45 ENST00000541909.1
ENST00000313546.3
POC1 centriolar protein B
chr5_+_52083730 0.45 ENST00000282588.6
ENST00000274311.2
integrin, alpha 1
pelota homolog (Drosophila)
chr4_-_129491686 0.45 ENST00000514265.1
RP11-184M15.1
chr6_+_24775641 0.44 ENST00000378054.2
ENST00000476555.1
geminin, DNA replication inhibitor
chr17_+_60501228 0.43 ENST00000311506.5
methyltransferase like 2A
chr17_+_33914424 0.43 ENST00000590432.1
adaptor-related protein complex 2, beta 1 subunit
chr17_+_34890807 0.43 ENST00000429467.2
ENST00000592983.1
phosphatidylinositol glycan anchor biosynthesis, class W
chr15_-_65579177 0.42 ENST00000444347.2
ENST00000261888.6
poly (ADP-ribose) polymerase family, member 16
chr11_+_65627865 0.42 ENST00000308110.4
MUS81 structure-specific endonuclease subunit
chr17_-_6524159 0.42 ENST00000589033.1
KIAA0753
chr9_-_111882195 0.41 ENST00000374586.3
transmembrane protein 245
chr1_+_173793641 0.40 ENST00000361951.4
aspartyl-tRNA synthetase 2, mitochondrial
chr2_-_175462456 0.40 ENST00000409891.1
ENST00000410117.1
WAS/WASL interacting protein family, member 1
chr14_+_31494841 0.40 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
adaptor-related protein complex 4, sigma 1 subunit
chr7_-_150777949 0.40 ENST00000482571.1
Fas-activated serine/threonine kinase
chr10_+_121652204 0.40 ENST00000369075.3
ENST00000543134.1
SEC23 interacting protein
chr8_-_121457608 0.40 ENST00000306185.3
mitochondrial ribosomal protein L13
chr12_-_57039739 0.39 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr12_+_118454500 0.39 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
replication factor C (activator 1) 5, 36.5kDa
chr14_+_31494672 0.39 ENST00000542754.2
ENST00000313566.6
adaptor-related protein complex 4, sigma 1 subunit
chr1_-_173793246 0.39 ENST00000345664.6
ENST00000367710.3
centromere protein L
chr6_-_131299929 0.39 ENST00000531356.1
erythrocyte membrane protein band 4.1-like 2
chr17_+_41150793 0.38 ENST00000586277.1
ribosomal protein L27
chr17_+_58755184 0.38 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr9_-_4859260 0.38 ENST00000599351.1
HCG2011465; Uncharacterized protein
chr4_+_113739244 0.38 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ankyrin 2, neuronal
chr1_+_110162448 0.37 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
adenosine monophosphate deaminase 2
chr14_-_31856397 0.37 ENST00000538864.2
ENST00000550366.1
HEAT repeat containing 5A
chr3_-_39196049 0.36 ENST00000514182.1
cysteine-serine-rich nuclear protein 1
chrX_-_47518527 0.35 ENST00000333119.3
ubiquitously-expressed, prefoldin-like chaperone
chr20_-_36793663 0.34 ENST00000536701.1
ENST00000536724.1
transglutaminase 2
chr2_-_69180083 0.34 ENST00000328895.4
gastrokine 2
chr4_-_170924888 0.34 ENST00000502832.1
ENST00000393704.3
microfibrillar-associated protein 3-like
chr1_-_149785236 0.34 ENST00000331491.1
histone cluster 2, H3d
chr12_-_109531264 0.34 ENST00000429722.2
ENST00000536242.1
ENST00000343075.3
ENST00000536358.1
alkB, alkylation repair homolog 2 (E. coli)
chr17_-_34890732 0.33 ENST00000268852.9
myosin XIX
chr8_+_99076750 0.33 ENST00000545282.1
chromosome 8 open reading frame 47
chr19_+_42746927 0.33 ENST00000378108.1
AC006486.1
chr9_+_116263639 0.33 ENST00000343817.5
regulator of G-protein signaling 3
chr1_-_160001737 0.33 ENST00000368090.2
phosphatidylinositol glycan anchor biosynthesis, class M
chr1_+_173793777 0.33 ENST00000239457.5
aspartyl-tRNA synthetase 2, mitochondrial
chr17_-_41116454 0.32 ENST00000427569.2
ENST00000430739.1
alanyl-tRNA synthetase domain containing 1
chr13_-_26452679 0.31 ENST00000596729.1
Uncharacterized protein
chrX_-_47518498 0.31 ENST00000335890.2
ubiquitously-expressed, prefoldin-like chaperone
chr2_-_202298268 0.31 ENST00000440597.1
trafficking protein, kinesin binding 2
chr9_+_134065506 0.31 ENST00000483497.2
nucleoporin 214kDa
chr14_-_60337684 0.30 ENST00000267484.5
reticulon 1
chr17_-_47723943 0.30 ENST00000510476.1
ENST00000503676.1
speckle-type POZ protein
chr6_+_10528560 0.30 ENST00000379597.3
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr17_-_34890759 0.30 ENST00000431794.3
myosin XIX
chr1_-_115259337 0.30 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr1_-_173793458 0.30 ENST00000356198.2
centromere protein L
chr2_+_219246746 0.29 ENST00000233202.6
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr14_+_50779071 0.29 ENST00000426751.2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr16_+_69373323 0.28 ENST00000254940.5
NIP7, nucleolar pre-rRNA processing protein
chr3_-_160167301 0.28 ENST00000494486.1
tripartite motif containing 59
chr12_+_120031264 0.28 ENST00000426426.1
transmembrane protein 233
chr19_-_44174330 0.27 ENST00000340093.3
plasminogen activator, urokinase receptor
chr3_+_37034823 0.27 ENST00000231790.2
ENST00000456676.2
mutL homolog 1
chr2_-_36779411 0.26 ENST00000406220.1
Uncharacterized protein
chr1_-_200638964 0.26 ENST00000367348.3
ENST00000447706.2
ENST00000331314.6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr11_+_94277017 0.26 ENST00000358752.2
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr11_-_64527425 0.25 ENST00000377432.3
phosphorylase, glycogen, muscle
chr12_-_39300071 0.25 ENST00000550863.1
copine VIII
chr11_-_76381029 0.25 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr8_-_82644562 0.24 ENST00000520604.1
ENST00000521742.1
ENST00000520635.1
zinc finger, AN1-type domain 1
chr9_-_134406611 0.24 ENST00000372208.3
ENST00000372215.4
uridine-cytidine kinase 1
chr9_+_134065519 0.24 ENST00000531600.1
nucleoporin 214kDa
chr13_-_88463487 0.24 ENST00000606221.1
RP11-471M2.3
chr6_-_144416737 0.24 ENST00000367569.2
splicing factor 3b, subunit 5, 10kDa
chr9_-_70465758 0.24 ENST00000489273.1
COBW domain containing 5
chr17_-_74049720 0.24 ENST00000602720.1
signal recognition particle 68kDa
chr10_-_91403625 0.23 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
pantothenate kinase 1
chr3_+_32726620 0.23 ENST00000331889.6
ENST00000328834.5
CCR4-NOT transcription complex, subunit 10
chr19_+_56111680 0.23 ENST00000301073.3
zinc finger protein 524
chr19_+_52076425 0.22 ENST00000436511.2
zinc finger protein 175
chr5_-_139937895 0.22 ENST00000336283.6
steroid receptor RNA activator 1
chr3_+_140981456 0.22 ENST00000504264.1
acid phosphatase-like 2
chr3_-_81811312 0.22 ENST00000429644.2
glucan (1,4-alpha-), branching enzyme 1
chr22_+_42017987 0.22 ENST00000405506.1
X-ray repair complementing defective repair in Chinese hamster cells 6
chr16_+_69796209 0.22 ENST00000359154.2
ENST00000561780.1
ENST00000563659.1
ENST00000448661.1
WW domain containing E3 ubiquitin protein ligase 2
chr7_+_16700806 0.21 ENST00000446596.1
ENST00000438834.1
basic leucine zipper and W2 domains 2
chr13_+_27998681 0.21 ENST00000381140.4
general transcription factor IIIA
chr17_-_7216939 0.21 ENST00000573684.1
G protein pathway suppressor 2
chr4_+_169418195 0.21 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr1_+_110163202 0.20 ENST00000531203.1
ENST00000256578.3
adenosine monophosphate deaminase 2
chr12_+_44152740 0.20 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
interleukin-1 receptor-associated kinase 4
chr15_+_43425672 0.20 ENST00000260403.2
transmembrane protein 62
chr1_+_171217677 0.20 ENST00000402921.2
flavin containing monooxygenase 1
chr1_+_159796534 0.20 ENST00000289707.5
SLAM family member 8
chr9_-_33402506 0.20 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
aquaporin 7
chr19_+_3178736 0.19 ENST00000246115.3
sphingosine-1-phosphate receptor 4
chr2_+_86426478 0.18 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
mitochondrial ribosomal protein L35
chr19_-_44174305 0.18 ENST00000601723.1
ENST00000339082.3
plasminogen activator, urokinase receptor
chr5_+_140071011 0.18 ENST00000230771.3
ENST00000509299.1
ENST00000503873.1
ENST00000435019.2
ENST00000437649.2
ENST00000432671.2
histidyl-tRNA synthetase 2, mitochondrial
chr10_+_32735030 0.18 ENST00000277657.6
ENST00000362006.5
coiled-coil domain containing 7
chr6_-_15586238 0.18 ENST00000462989.2
dystrobrevin binding protein 1
chr2_-_220252530 0.18 ENST00000521459.1
aspartyl aminopeptidase
chr12_-_68845165 0.18 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2
chr3_+_156807663 0.17 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
long intergenic non-protein coding RNA 881
chr3_-_39234074 0.17 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
xin actin-binding repeat containing 1
chr5_+_173763250 0.17 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
chr16_-_47493041 0.17 ENST00000565940.2
integrin alpha FG-GAP repeat containing 1
chr3_-_42003479 0.17 ENST00000420927.1
unc-51 like kinase 4
chr1_+_19578033 0.17 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr12_-_44152551 0.17 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr18_+_7754957 0.17 ENST00000400053.4
protein tyrosine phosphatase, receptor type, M
chr4_-_79860506 0.16 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
progestin and adipoQ receptor family member III
chr7_+_75511362 0.16 ENST00000428119.1
rhomboid domain containing 2
chr3_+_186435137 0.16 ENST00000447445.1
kininogen 1
chr18_-_10791648 0.16 ENST00000583325.1
piezo-type mechanosensitive ion channel component 2
chr8_-_30706608 0.16 ENST00000256246.2
testis expressed 15
chr3_+_32726774 0.16 ENST00000538368.1
CCR4-NOT transcription complex, subunit 10
chr6_-_72129806 0.15 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
long intergenic non-protein coding RNA 472
chr19_+_10563567 0.15 ENST00000344979.3
phosphodiesterase 4A, cAMP-specific
chr10_-_101841588 0.15 ENST00000370418.3
carboxypeptidase N, polypeptide 1
chr3_+_186158169 0.15 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1
chr4_+_186317133 0.15 ENST00000507753.1
ankyrin repeat domain 37
chr7_+_75544466 0.15 ENST00000421059.1
ENST00000394893.1
ENST00000412521.1
ENST00000414186.1
P450 (cytochrome) oxidoreductase
chr19_-_56110859 0.15 ENST00000221665.3
ENST00000592585.1
FLT3-interacting zinc finger 1
chr11_-_66360548 0.15 ENST00000333861.3
coiled-coil domain containing 87
chr20_-_36661826 0.15 ENST00000373448.2
ENST00000373447.3
TELO2 interacting protein 1
chr2_-_69180012 0.15 ENST00000481498.1
gastrokine 2
chr20_-_21494654 0.15 ENST00000377142.4
NK2 homeobox 2
chr9_+_125281420 0.14 ENST00000340750.1
olfactory receptor, family 1, subfamily J, member 4
chr9_+_4839762 0.14 ENST00000448872.2
ENST00000441844.1
RNA terminal phosphate cyclase-like 1
chr1_+_202172848 0.14 ENST00000255432.7
leucine-rich repeat containing G protein-coupled receptor 6
chr12_+_32259696 0.14 ENST00000551848.1
bicaudal D homolog 1 (Drosophila)
chr22_-_24096630 0.14 ENST00000248948.3
pre-B lymphocyte 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 0.9 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.3 1.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 2.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 2.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 0.9 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 0.6 GO:0060061 Spemann organizer formation(GO:0060061)
0.2 1.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 0.7 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 1.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 1.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.5 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.6 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.3 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.3 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.3 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.1 0.5 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.7 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.3 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 3.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 1.0 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 1.3 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.6 GO:0032264 IMP salvage(GO:0032264)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.4 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 0.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.5 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0061565 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.3 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0015793 glycerol transport(GO:0015793)
0.0 0.7 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.5 GO:0042255 ribosome assembly(GO:0042255)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005715 late recombination nodule(GO:0005715)
0.3 0.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 1.0 GO:0000811 GINS complex(GO:0000811)
0.2 1.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.5 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.1 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.5 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 0.5 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.3 GO:0070652 HAUS complex(GO:0070652)
0.1 1.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.5 GO:0045178 basal part of cell(GO:0045178)
0.1 1.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 1.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.8 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 3.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.8 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.4 1.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.4 1.8 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 1.0 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.3 3.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.3 1.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.2 0.9 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.2 1.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.5 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.1 0.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.5 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.7 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.9 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.3 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.3 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.1 0.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 1.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.5 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.5 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 2.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.0 1.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.6 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 2.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism