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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR1H2

Z-value: 1.38

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Transcription factors associated with NR1H2

Gene Symbol Gene ID Gene Info
NR1H2
ENSG00000131408.9 nuclear receptor subfamily 1 group H member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H2hg19_v2_chr19_+_50879705_508797750.962.2e-11Click!

Activity profile of NR1H2 motif

Sorted Z-values of NR1H2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_124749609 5.70 ENST00000262219.6
ENST00000419625.1
ANXA13
annexin A13
chr17_-_19648916 4.50 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr20_+_43343886 4.08 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr19_-_38747172 3.86 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr14_-_102976135 3.78 ENST00000560748.1
ANKRD9
ankyrin repeat domain 9
chr20_+_43343517 3.40 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr2_-_216946500 3.38 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr17_+_77019030 3.35 ENST00000580454.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr20_+_34679725 3.22 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr17_-_76183111 3.09 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1
thymidine kinase 1, soluble
chr19_-_38806540 3.09 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_+_844406 3.08 ENST00000397404.1
TSPAN4
tetraspanin 4
chr8_-_61193947 2.80 ENST00000317995.4
CA8
carbonic anhydrase VIII
chr8_-_48651648 2.78 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr17_-_17480779 2.76 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr17_+_77018896 2.75 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_-_26695013 2.64 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr16_-_2205352 2.57 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr2_+_223725723 2.55 ENST00000535678.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr6_+_30687978 2.40 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr17_-_26694979 2.40 ENST00000438614.1
VTN
vitronectin
chr19_+_41092680 2.39 ENST00000594298.1
ENST00000597396.1
SHKBP1
SH3KBP1 binding protein 1
chr19_+_15751689 2.38 ENST00000586182.2
ENST00000591058.1
ENST00000221307.8
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr2_-_74699770 2.37 ENST00000409710.1
MRPL53
mitochondrial ribosomal protein L53
chr19_+_2977444 2.36 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr15_-_63674218 2.35 ENST00000178638.3
CA12
carbonic anhydrase XII
chr20_+_5987890 2.35 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr19_-_38806560 2.30 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr19_-_38806390 2.26 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr12_+_22778009 2.19 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr19_-_46285646 2.16 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr20_-_32262165 2.11 ENST00000606690.1
ENST00000246190.6
ENST00000439478.1
ENST00000375238.4
NECAB3
N-terminal EF-hand calcium binding protein 3
chr16_+_577697 2.05 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr2_+_228029281 2.03 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr19_+_15752088 1.97 ENST00000585846.1
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr5_-_58652788 1.95 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_34287174 1.93 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr2_+_216946589 1.90 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chrX_+_1455478 1.87 ENST00000331035.4
IL3RA
interleukin 3 receptor, alpha (low affinity)
chr20_+_34680595 1.86 ENST00000406771.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_+_169075554 1.83 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_-_49893958 1.78 ENST00000482243.1
ENST00000331456.2
ENST00000469027.1
TRAIP
TRAF interacting protein
chr19_-_17622684 1.78 ENST00000596643.1
CTD-3131K8.2
CTD-3131K8.2
chr11_+_62652649 1.75 ENST00000539507.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr15_-_102285007 1.75 ENST00000560292.2
RP11-89K11.1
Uncharacterized protein
chr11_+_65190245 1.70 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr16_-_30023615 1.65 ENST00000564979.1
ENST00000563378.1
DOC2A
double C2-like domains, alpha
chr15_+_89010923 1.60 ENST00000353598.6
MRPS11
mitochondrial ribosomal protein S11
chr14_-_102976091 1.60 ENST00000286918.4
ANKRD9
ankyrin repeat domain 9
chr1_+_10459111 1.60 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD
phosphogluconate dehydrogenase
chr12_+_22778116 1.60 ENST00000538218.1
ETNK1
ethanolamine kinase 1
chr20_+_34680620 1.55 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr8_+_142402089 1.51 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr17_+_42977122 1.45 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
FAM187A
CCDC103
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr1_-_153950098 1.40 ENST00000356648.1
JTB
jumping translocation breakpoint
chr17_+_4675175 1.37 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr19_+_33071974 1.32 ENST00000590247.2
ENST00000419343.3
ENST00000592786.1
ENST00000379316.3
PDCD5
programmed cell death 5
chr19_+_15783879 1.29 ENST00000551607.1
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chrX_+_52240504 1.28 ENST00000399805.2
XAGE1B
X antigen family, member 1B
chr4_-_140216948 1.25 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr9_+_67977438 1.25 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr12_+_57998400 1.24 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr12_+_122064398 1.21 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr10_-_72648541 1.20 ENST00000299299.3
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr15_-_89010607 1.19 ENST00000312475.4
MRPL46
mitochondrial ribosomal protein L46
chr19_-_49121054 1.17 ENST00000546623.1
ENST00000084795.5
RPL18
ribosomal protein L18
chrX_+_102631248 1.15 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_-_46649905 1.14 ENST00000569702.1
SHCBP1
SHC SH2-domain binding protein 1
chr14_-_93673353 1.12 ENST00000556566.1
ENST00000306954.4
C14orf142
chromosome 14 open reading frame 142
chr7_+_100136811 1.11 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr16_-_4465886 1.11 ENST00000539968.1
CORO7
coronin 7
chr17_+_70026795 1.10 ENST00000472655.2
ENST00000538810.1
RP11-84E24.3
long intergenic non-protein coding RNA 1152
chr7_-_73153161 1.10 ENST00000395147.4
ABHD11
abhydrolase domain containing 11
chr11_-_61596753 1.07 ENST00000448607.1
ENST00000421879.1
FADS1
fatty acid desaturase 1
chr2_+_73441350 1.07 ENST00000389501.4
SMYD5
SMYD family member 5
chr17_-_8151353 1.06 ENST00000315684.8
CTC1
CTS telomere maintenance complex component 1
chrX_-_107334790 1.06 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr17_-_8198636 1.05 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr7_-_73153122 1.05 ENST00000458339.1
ABHD11
abhydrolase domain containing 11
chr19_+_17865011 1.05 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCHO1
FCH domain only 1
chr3_-_127309550 1.04 ENST00000296210.7
ENST00000355552.3
TPRA1
transmembrane protein, adipocyte asscociated 1
chr14_-_59950724 1.00 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr1_+_45274154 0.97 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr1_-_153919128 0.97 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr19_+_1077393 0.95 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr12_-_91573132 0.95 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr19_+_17622415 0.95 ENST00000252603.2
ENST00000600923.1
PGLS
6-phosphogluconolactonase
chr19_+_39881951 0.95 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr19_+_50094866 0.90 ENST00000418929.2
PRR12
proline rich 12
chr22_-_24096630 0.90 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr2_+_44502597 0.89 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr19_-_36391434 0.89 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr10_-_70287172 0.88 ENST00000539557.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr4_-_84205905 0.87 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
COQ2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr1_-_153949751 0.87 ENST00000428469.1
JTB
jumping translocation breakpoint
chr15_+_75498739 0.86 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chrX_-_107334750 0.84 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr17_+_48351785 0.83 ENST00000507382.1
TMEM92
transmembrane protein 92
chr17_-_41977964 0.83 ENST00000377184.3
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr8_-_145652336 0.82 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr5_-_133968529 0.82 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr11_+_86748863 0.81 ENST00000340353.7
TMEM135
transmembrane protein 135
chr4_+_183164574 0.78 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr19_+_56146352 0.78 ENST00000592881.1
ZNF580
zinc finger protein 580
chr16_-_1661988 0.78 ENST00000426508.2
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr16_+_72042487 0.76 ENST00000572887.1
ENST00000219240.4
ENST00000574309.1
ENST00000576145.1
DHODH
dihydroorotate dehydrogenase (quinone)
chr9_-_98189055 0.76 ENST00000433644.2
RP11-435O5.2
RP11-435O5.2
chr17_-_27054952 0.75 ENST00000580518.1
TLCD1
TLC domain containing 1
chr1_-_40098672 0.75 ENST00000535435.1
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr12_+_100594557 0.74 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr19_+_3224700 0.73 ENST00000292672.2
ENST00000541430.2
CELF5
CUGBP, Elav-like family member 5
chr22_-_38480100 0.71 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr3_-_127309879 0.71 ENST00000489960.1
ENST00000490290.1
TPRA1
transmembrane protein, adipocyte asscociated 1
chr17_+_34087888 0.70 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
C17orf50
chromosome 17 open reading frame 50
chr11_+_827248 0.69 ENST00000527089.1
ENST00000530183.1
EFCAB4A
EF-hand calcium binding domain 4A
chr2_-_32390801 0.69 ENST00000608489.1
RP11-563N4.1
RP11-563N4.1
chr1_-_201476220 0.68 ENST00000526723.1
ENST00000524951.1
CSRP1
cysteine and glycine-rich protein 1
chr14_-_70826438 0.65 ENST00000389912.6
COX16
COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr22_-_38577782 0.65 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr14_+_77787227 0.65 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1
glutathione S-transferase zeta 1
chr17_-_3595042 0.64 ENST00000552723.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr22_-_24096562 0.64 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr3_+_52007693 0.63 ENST00000494478.1
ABHD14A
abhydrolase domain containing 14A
chr22_-_23974506 0.62 ENST00000317749.5
C22orf43
chromosome 22 open reading frame 43
chr2_+_145425573 0.61 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
TEX41
testis expressed 41 (non-protein coding)
chr22_+_19118321 0.61 ENST00000399635.2
TSSK2
testis-specific serine kinase 2
chr12_-_91573249 0.61 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr19_+_33622996 0.57 ENST00000592765.1
ENST00000361680.2
ENST00000355868.3
WDR88
WD repeat domain 88
chr14_-_80782219 0.56 ENST00000553594.1
DIO2
deiodinase, iodothyronine, type II
chr11_+_119039414 0.56 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLRX1
NLR family member X1
chr1_+_6615241 0.56 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr11_-_82611448 0.56 ENST00000393399.2
ENST00000313010.3
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr9_-_36400213 0.54 ENST00000259605.6
ENST00000353739.4
RNF38
ring finger protein 38
chrX_+_49020121 0.54 ENST00000415364.1
ENST00000376338.3
ENST00000425285.1
MAGIX
MAGI family member, X-linked
chr11_+_10326612 0.54 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr4_-_83483395 0.51 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr22_-_33968239 0.49 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr22_-_38577731 0.49 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr11_-_68519026 0.49 ENST00000255087.5
MTL5
metallothionein-like 5, testis-specific (tesmin)
chr11_-_798239 0.49 ENST00000531437.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr17_-_15370915 0.49 ENST00000312177.6
CDRT4
CMT1A duplicated region transcript 4
chr1_+_100818009 0.48 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr2_+_32390925 0.46 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr8_-_93115445 0.46 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_-_6677422 0.44 ENST00000382421.3
ENST00000545200.1
ENST00000399466.2
ENST00000536124.1
ENST00000540228.1
ENST00000542867.1
ENST00000545492.1
ENST00000322166.5
ENST00000545915.1
NOP2
NOP2 nucleolar protein
chr15_+_91473403 0.44 ENST00000394275.2
UNC45A
unc-45 homolog A (C. elegans)
chr11_+_61159832 0.42 ENST00000334888.5
ENST00000398979.3
TMEM216
transmembrane protein 216
chr20_+_35918035 0.42 ENST00000373606.3
ENST00000397156.3
ENST00000397150.1
ENST00000397152.3
MANBAL
mannosidase, beta A, lysosomal-like
chr16_+_4674787 0.41 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr10_+_101491968 0.41 ENST00000370476.5
ENST00000370472.4
CUTC
cutC copper transporter
chr15_+_74610894 0.41 ENST00000558821.1
ENST00000268082.4
CCDC33
coiled-coil domain containing 33
chr5_+_446253 0.39 ENST00000315013.5
EXOC3
exocyst complex component 3
chr3_-_49466686 0.39 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chr16_+_4674814 0.39 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr7_+_2687173 0.38 ENST00000403167.1
TTYH3
tweety family member 3
chr17_+_60457914 0.38 ENST00000305286.3
ENST00000520404.1
ENST00000518576.1
EFCAB3
EF-hand calcium binding domain 3
chr16_+_29467780 0.38 ENST00000395400.3
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr16_-_14788526 0.38 ENST00000438167.3
PLA2G10
phospholipase A2, group X
chr2_+_145425534 0.37 ENST00000432608.1
ENST00000597655.1
ENST00000598659.1
ENST00000600679.1
ENST00000601277.1
ENST00000451027.1
ENST00000445791.1
ENST00000596540.1
ENST00000596230.1
ENST00000594471.1
ENST00000598248.1
ENST00000597469.1
ENST00000431734.1
ENST00000595686.1
TEX41
testis expressed 41 (non-protein coding)
chr11_-_68518910 0.37 ENST00000544963.1
ENST00000443940.2
MTL5
metallothionein-like 5, testis-specific (tesmin)
chr12_-_56122761 0.37 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63
CD63 molecule
chr19_-_50420918 0.36 ENST00000595761.1
NUP62
nucleoporin 62kDa
chr3_-_114173530 0.36 ENST00000470311.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_-_62420757 0.36 ENST00000330574.2
INTS5
integrator complex subunit 5
chr19_-_46296011 0.36 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr14_-_22005062 0.36 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr16_+_29973351 0.35 ENST00000602948.1
ENST00000279396.6
ENST00000575829.2
ENST00000561899.2
TMEM219
transmembrane protein 219
chr2_+_207630081 0.35 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr20_-_44600810 0.34 ENST00000322927.2
ENST00000426788.1
ZNF335
zinc finger protein 335
chr16_+_57769635 0.34 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr4_-_39033963 0.34 ENST00000381938.3
TMEM156
transmembrane protein 156
chr12_-_9913489 0.34 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr19_+_41768401 0.34 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr16_+_30484021 0.33 ENST00000358164.5
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr4_+_108910870 0.33 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
HADH
hydroxyacyl-CoA dehydrogenase
chr2_+_27255806 0.33 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr5_-_137374288 0.33 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr15_+_67835517 0.32 ENST00000395476.2
MAP2K5
mitogen-activated protein kinase kinase 5
chr7_+_56131917 0.31 ENST00000434526.2
ENST00000275607.9
ENST00000395435.2
ENST00000413952.2
ENST00000342190.6
ENST00000437307.2
ENST00000413756.1
ENST00000451338.1
SUMF2
sulfatase modifying factor 2
chr11_+_119038897 0.31 ENST00000454811.1
ENST00000449394.1
NLRX1
NLR family member X1
chr7_-_56160625 0.31 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr13_+_49684445 0.31 ENST00000398316.3
FNDC3A
fibronectin type III domain containing 3A
chr8_-_121457332 0.30 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr12_-_125398850 0.30 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
UBC
ubiquitin C
chr11_+_66276550 0.30 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr7_+_16700806 0.29 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr2_-_114036488 0.29 ENST00000263335.7
ENST00000397647.3
ENST00000348715.5
ENST00000429538.3
PAX8
paired box 8
chr14_-_77787198 0.29 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr8_+_145218673 0.29 ENST00000326134.5
MROH1
maestro heat-like repeat family member 1
chr11_+_86748998 0.28 ENST00000525018.1
ENST00000355734.4
TMEM135
transmembrane protein 135
chr14_-_22005343 0.28 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr15_+_81589254 0.27 ENST00000394652.2
IL16
interleukin 16
chr17_-_5026397 0.27 ENST00000250076.3
ZNF232
zinc finger protein 232
chr17_+_78152274 0.26 ENST00000344227.2
ENST00000570421.1
CARD14
caspase recruitment domain family, member 14
chr17_+_42977062 0.26 ENST00000410006.2
ENST00000357776.2
ENST00000410027.1
CCDC103
coiled-coil domain containing 103
chr19_+_39930212 0.26 ENST00000396843.1
AC011500.1
Interleukin-like; Uncharacterized protein
chr15_-_90892669 0.25 ENST00000412799.2
GABARAPL3
GABA(A) receptors associated protein like 3, pseudogene
chr1_+_22962948 0.24 ENST00000374642.3
C1QA
complement component 1, q subcomponent, A chain
chr21_-_46340770 0.23 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr22_-_26875345 0.23 ENST00000398141.1
HPS4
Hermansky-Pudlak syndrome 4

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.6 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.8 6.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.5 1.4 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.4 3.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.4 2.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 1.9 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.3 1.9 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.3 2.8 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.3 0.8 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.3 1.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.3 2.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 1.8 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.3 2.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.3 2.3 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.3 3.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 0.8 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.3 1.8 GO:0060356 leucine import(GO:0060356)
0.2 0.7 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.2 1.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 1.5 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.2 2.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 1.1 GO:0048539 bone marrow development(GO:0048539)
0.1 1.7 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 2.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 3.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.9 GO:0015811 L-cystine transport(GO:0015811)
0.1 1.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.9 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1 1.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 2.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 6.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.3 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.6 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 2.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.9 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.6 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 0.2 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 1.2 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 1.1 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 1.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.5 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 2.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.9 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 4.5 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 2.7 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 4.2 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.8 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 1.1 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 1.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 3.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 8.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.8 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.0 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.6 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 2.3 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 2.0 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 2.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 2.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 7.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.1 1.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 2.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.6 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.4 GO:0005874 microtubule(GO:0005874)
0.1 0.7 GO:0060091 kinocilium(GO:0060091)
0.1 6.1 GO:0005581 collagen trimer(GO:0005581)
0.1 3.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 5.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 3.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 1.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 4.1 GO:0030496 midbody(GO:0030496)
0.0 7.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.7 GO:0031966 mitochondrial membrane(GO:0031966)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
1.1 3.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.9 2.8 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.8 2.3 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.5 3.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.5 4.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 1.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 1.2 GO:0008124 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.4 1.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.4 1.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.3 3.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 1.0 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.3 1.3 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.3 1.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 0.9 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.3 5.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 0.9 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 0.8 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2 0.7 GO:0035939 microsatellite binding(GO:0035939)
0.2 7.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.9 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 2.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 2.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 7.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 1.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 7.7 GO:0005518 collagen binding(GO:0005518)
0.1 0.6 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 3.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 5.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.0 GO:0004794 L-serine ammonia-lyase activity(GO:0003941) L-threonine ammonia-lyase activity(GO:0004794)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 2.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 2.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 12.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 7.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 3.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 3.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 6.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 5.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.9 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 1.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 2.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 5.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing