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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR2C1

Z-value: 0.52

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Transcription factors associated with NR2C1

Gene Symbol Gene ID Gene Info
NR2C1
ENSG00000120798.12 nuclear receptor subfamily 2 group C member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2C1hg19_v2_chr12_-_95467356_95467479-0.706.5e-04Click!

Activity profile of NR2C1 motif

Sorted Z-values of NR2C1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39743139 3.56 ENST00000167586.6
KRT14
keratin 14
chr1_-_156675564 2.28 ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr15_-_45422056 1.76 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
DUOXA1
dual oxidase maturation factor 1
chr15_+_45422178 1.66 ENST00000389037.3
ENST00000558322.1
DUOX1
dual oxidase 1
chr15_+_45422131 1.52 ENST00000321429.4
DUOX1
dual oxidase 1
chr11_+_131781290 1.18 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr19_-_51472031 1.06 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr5_-_1801408 1.02 ENST00000505818.1
MRPL36
mitochondrial ribosomal protein L36
chr10_+_63808970 0.94 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr4_+_26321284 0.75 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr5_-_42811986 0.74 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr22_+_41777927 0.70 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr6_+_43737939 0.70 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr6_-_160147925 0.68 ENST00000535561.1
SOD2
superoxide dismutase 2, mitochondrial
chr10_+_127661942 0.67 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr2_-_163099885 0.65 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr19_-_46142362 0.65 ENST00000586770.1
ENST00000591721.1
EML2
echinoderm microtubule associated protein like 2
chr19_+_6464243 0.65 ENST00000600229.1
ENST00000356762.3
CRB3
crumbs homolog 3 (Drosophila)
chr2_-_163100045 0.64 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr12_+_107349606 0.64 ENST00000547242.1
ENST00000551489.1
ENST00000550344.1
C12orf23
chromosome 12 open reading frame 23
chr19_-_10679697 0.63 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chrX_-_132095419 0.63 ENST00000370836.2
ENST00000521489.1
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr12_+_48499883 0.62 ENST00000546755.1
ENST00000549366.1
ENST00000552792.1
PFKM
phosphofructokinase, muscle
chr11_+_10471836 0.62 ENST00000444303.2
AMPD3
adenosine monophosphate deaminase 3
chr3_+_101546827 0.61 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr5_-_42812143 0.61 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr11_+_94501497 0.60 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
AMOTL1
angiomotin like 1
chr22_-_29784519 0.57 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr6_-_160148356 0.51 ENST00000401980.3
ENST00000545162.1
SOD2
superoxide dismutase 2, mitochondrial
chr19_+_10196981 0.51 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr19_+_10197463 0.51 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr6_-_31138439 0.50 ENST00000259915.8
POU5F1
POU class 5 homeobox 1
chr21_-_32931290 0.49 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr10_+_104005272 0.49 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr19_-_49371711 0.48 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr19_+_676385 0.44 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr4_+_159593418 0.43 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr19_-_4066890 0.43 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr13_+_21714653 0.42 ENST00000382533.4
SAP18
Sin3A-associated protein, 18kDa
chr1_+_44412577 0.42 ENST00000372343.3
IPO13
importin 13
chr18_+_8609402 0.42 ENST00000329286.6
RAB12
RAB12, member RAS oncogene family
chr11_-_65429891 0.42 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr7_+_143080063 0.42 ENST00000446634.1
ZYX
zyxin
chr10_+_24755416 0.41 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr3_+_107318157 0.40 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr18_+_54318566 0.39 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr1_-_29508321 0.39 ENST00000546138.1
SRSF4
serine/arginine-rich splicing factor 4
chr3_+_37284668 0.39 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
GOLGA4
golgin A4
chr9_+_33795533 0.39 ENST00000379405.3
PRSS3
protease, serine, 3
chr18_+_54318616 0.38 ENST00000254442.3
WDR7
WD repeat domain 7
chr2_-_201936302 0.37 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr7_+_100770328 0.36 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr8_-_80680078 0.35 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr6_+_31515337 0.35 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr7_+_121513143 0.34 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr10_-_103815874 0.34 ENST00000370033.4
ENST00000311122.5
C10orf76
chromosome 10 open reading frame 76
chr18_+_54318893 0.33 ENST00000593058.1
WDR7
WD repeat domain 7
chr14_-_73360796 0.31 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr20_+_44486246 0.31 ENST00000255152.2
ENST00000454862.2
ZSWIM3
zinc finger, SWIM-type containing 3
chr2_+_201936458 0.31 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr12_+_96252706 0.30 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr16_+_30710462 0.30 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr12_-_6665200 0.29 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
IFFO1
intermediate filament family orphan 1
chr14_-_21492251 0.29 ENST00000554398.1
NDRG2
NDRG family member 2
chr6_+_30594619 0.28 ENST00000318999.7
ENST00000376485.4
ENST00000376478.2
ENST00000319027.5
ENST00000376483.4
ENST00000329992.8
ENST00000330083.5
ATAT1
alpha tubulin acetyltransferase 1
chr15_-_43802769 0.28 ENST00000263801.3
TP53BP1
tumor protein p53 binding protein 1
chr11_-_65430554 0.26 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr22_+_47158578 0.26 ENST00000355704.3
TBC1D22A
TBC1 domain family, member 22A
chr12_-_109219937 0.26 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr1_-_917466 0.26 ENST00000341290.2
C1orf170
chromosome 1 open reading frame 170
chr19_+_16771936 0.26 ENST00000187762.2
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr12_+_6494285 0.26 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr3_+_183903811 0.25 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr1_-_31381528 0.24 ENST00000339394.6
SDC3
syndecan 3
chr13_-_103046837 0.24 ENST00000607251.1
FGF14-IT1
FGF14 intronic transcript 1 (non-protein coding)
chr19_+_6464502 0.24 ENST00000308243.7
CRB3
crumbs homolog 3 (Drosophila)
chr14_-_21492113 0.24 ENST00000554094.1
NDRG2
NDRG family member 2
chr13_+_21714711 0.23 ENST00000607003.1
ENST00000492245.1
SAP18
Sin3A-associated protein, 18kDa
chr20_+_19870167 0.23 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr2_-_163099546 0.23 ENST00000447386.1
FAP
fibroblast activation protein, alpha
chr1_-_226374373 0.23 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr1_-_45140227 0.20 ENST00000372237.3
TMEM53
transmembrane protein 53
chr15_+_90728145 0.20 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr1_-_155881156 0.20 ENST00000539040.1
ENST00000368323.3
RIT1
Ras-like without CAAX 1
chr3_+_14989186 0.19 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr1_+_26872324 0.19 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr14_+_21492331 0.19 ENST00000533984.1
ENST00000532213.2
AL161668.5
AL161668.5
chr4_-_151936416 0.18 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr14_-_65289812 0.18 ENST00000389720.3
ENST00000389721.5
ENST00000389722.3
SPTB
spectrin, beta, erythrocytic
chr6_+_149068464 0.18 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr22_+_47158518 0.18 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
TBC1D22A
TBC1 domain family, member 22A
chr11_-_72414430 0.17 ENST00000452383.2
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr22_-_38851205 0.16 ENST00000303592.3
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr22_-_31536480 0.16 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr1_-_155880672 0.15 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr2_+_120124497 0.15 ENST00000355857.3
ENST00000535617.1
ENST00000535757.1
ENST00000409094.1
ENST00000311521.4
DBI
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr4_-_76598296 0.15 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr9_-_35685452 0.14 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr11_-_63684316 0.14 ENST00000301459.4
RCOR2
REST corepressor 2
chr11_-_45939565 0.14 ENST00000525192.1
ENST00000378750.5
PEX16
peroxisomal biogenesis factor 16
chr13_-_33760216 0.14 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr19_-_51289374 0.14 ENST00000563228.1
CTD-2568A17.1
CTD-2568A17.1
chr1_+_110577229 0.13 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr15_-_43863695 0.13 ENST00000439195.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr4_-_99064387 0.13 ENST00000295268.3
STPG2
sperm-tail PG-rich repeat containing 2
chr2_+_109745655 0.13 ENST00000418513.1
SH3RF3
SH3 domain containing ring finger 3
chr12_-_109797249 0.13 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr1_-_55089191 0.13 ENST00000302250.2
ENST00000371304.2
FAM151A
family with sequence similarity 151, member A
chr1_+_45140400 0.12 ENST00000453711.1
C1orf228
chromosome 1 open reading frame 228
chr9_+_140513438 0.12 ENST00000462484.1
ENST00000334856.6
ENST00000460843.1
EHMT1
euchromatic histone-lysine N-methyltransferase 1
chr1_+_25071848 0.12 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr5_+_179125907 0.11 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
CANX
calnexin
chr18_-_54318353 0.11 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr19_-_36304201 0.11 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr13_+_100741269 0.11 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
PCCA
propionyl CoA carboxylase, alpha polypeptide
chr12_-_118810688 0.10 ENST00000542532.1
ENST00000392533.3
TAOK3
TAO kinase 3
chr8_+_70404996 0.10 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr11_-_72414256 0.10 ENST00000427971.2
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr6_+_160148593 0.10 ENST00000337387.4
WTAP
Wilms tumor 1 associated protein
chr9_-_16253112 0.09 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr2_+_151485403 0.09 ENST00000413247.1
ENST00000423428.1
ENST00000427615.1
ENST00000443811.1
AC104777.4
AC104777.4
chr3_+_37284824 0.09 ENST00000431105.1
GOLGA4
golgin A4
chr3_+_42897512 0.09 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr12_-_22487588 0.08 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr22_+_30163340 0.08 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr3_+_179065474 0.08 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr2_+_201936707 0.07 ENST00000433898.1
ENST00000454214.1
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr2_-_202316260 0.07 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr2_+_210636697 0.07 ENST00000439458.1
ENST00000272845.6
UNC80
unc-80 homolog (C. elegans)
chr10_-_23633720 0.06 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr1_-_173886491 0.06 ENST00000367698.3
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr2_-_74757066 0.06 ENST00000377526.3
AUP1
ancient ubiquitous protein 1
chr12_-_22487618 0.06 ENST00000404299.3
ENST00000396037.4
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr7_-_72936608 0.06 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr11_-_64013663 0.06 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_+_120969045 0.05 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr1_-_101491319 0.05 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr3_+_154801678 0.05 ENST00000462837.1
MME
membrane metallo-endopeptidase
chr12_-_48499826 0.04 ENST00000551798.1
SENP1
SUMO1/sentrin specific peptidase 1
chr13_+_103046954 0.04 ENST00000606448.1
FGF14-AS2
FGF14 antisense RNA 2
chr1_-_12679171 0.04 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr20_+_37590942 0.04 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr11_-_26743546 0.04 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr19_+_11350278 0.03 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr1_+_212797789 0.03 ENST00000294829.3
FAM71A
family with sequence similarity 71, member A
chr3_-_126236588 0.03 ENST00000383579.3
UROC1
urocanate hydratase 1
chr8_-_145028013 0.03 ENST00000354958.2
PLEC
plectin
chr15_+_65369082 0.03 ENST00000432196.2
KBTBD13
kelch repeat and BTB (POZ) domain containing 13
chr9_-_140513231 0.03 ENST00000371417.3
C9orf37
chromosome 9 open reading frame 37
chr2_+_120125245 0.03 ENST00000393103.2
DBI
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr2_-_96701722 0.02 ENST00000434632.1
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr7_-_38948774 0.02 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr16_-_88752889 0.02 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr17_-_49021974 0.02 ENST00000501718.2
RP11-700H6.1
RP11-700H6.1
chr2_-_154335300 0.02 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr14_+_105212297 0.02 ENST00000556623.1
ENST00000555674.1
ADSSL1
adenylosuccinate synthase like 1
chr9_-_34397800 0.02 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr20_+_30946106 0.02 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr8_+_77318769 0.02 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr19_-_48867291 0.02 ENST00000435956.3
TMEM143
transmembrane protein 143
chr3_-_126236605 0.01 ENST00000290868.2
UROC1
urocanate hydratase 1
chr1_-_45140074 0.01 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
TMEM53
transmembrane protein 53
chr16_-_4292071 0.01 ENST00000399609.3
SRL
sarcalumenin
chr2_-_219134343 0.01 ENST00000447885.1
ENST00000420660.1
AAMP
angio-associated, migratory cell protein
chr6_+_54172653 0.01 ENST00000370869.3
TINAG
tubulointerstitial nephritis antigen
chr2_-_219134822 0.00 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2C1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.5 3.2 GO:0042335 cuticle development(GO:0042335)
0.5 1.5 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.2 1.2 GO:0003070 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.2 0.7 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.7 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 1.8 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.2 0.6 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 0.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 2.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.7 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.5 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.1 0.6 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.7 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 1.0 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 1.0 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.9 GO:0016577 histone demethylation(GO:0016577)
0.0 1.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.3 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.1 1.5 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.0 3.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:1990254 keratin filament binding(GO:1990254)
0.2 3.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.4 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 1.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 2.3 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.1 0.4 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.7 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 3.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.2 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo