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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR2E1

Z-value: 0.79

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Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
NR2E1
ENSG00000112333.7 nuclear receptor subfamily 2 group E member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg19_v2_chr6_+_108487245_108487262-0.331.5e-01Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_75567962 4.42 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr10_-_21786179 2.71 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr15_-_88799384 2.26 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr12_+_54384370 2.00 ENST00000504315.1
HOXC6
homeobox C6
chr12_+_40618873 1.72 ENST00000298910.7
LRRK2
leucine-rich repeat kinase 2
chr9_-_119162885 1.62 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr16_-_15180257 1.48 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chrX_+_10031499 1.40 ENST00000454666.1
WWC3
WWC family member 3
chr12_-_120241187 1.40 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr12_-_90049828 1.39 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_+_40618764 1.36 ENST00000343742.2
LRRK2
leucine-rich repeat kinase 2
chr6_+_142623758 1.34 ENST00000541199.1
ENST00000435011.2
GPR126
G protein-coupled receptor 126
chr5_-_33892204 1.34 ENST00000504830.1
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr3_-_148939598 1.32 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr6_+_12290586 1.32 ENST00000379375.5
EDN1
endothelin 1
chr2_-_45162783 1.28 ENST00000432125.2
RP11-89K21.1
RP11-89K21.1
chr20_-_22565101 1.26 ENST00000419308.2
FOXA2
forkhead box A2
chr17_+_65027509 1.25 ENST00000375684.1
AC005544.1
Uncharacterized protein
chr2_+_198365122 1.23 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr2_-_111291587 1.23 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr2_+_145780739 1.23 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr16_+_81272287 1.21 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr12_-_90049878 1.20 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_53343633 1.19 ENST00000546826.1
KRT8
keratin 8
chr1_-_103574024 1.19 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1
collagen, type XI, alpha 1
chr7_-_107880508 1.13 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr12_+_86268065 1.12 ENST00000551529.1
ENST00000256010.6
NTS
neurotensin
chr17_+_36886478 1.12 ENST00000439660.2
CISD3
CDGSH iron sulfur domain 3
chr17_-_46667594 1.09 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3
homeobox B3
chr4_+_4861385 1.04 ENST00000382723.4
MSX1
msh homeobox 1
chr9_-_16727978 0.99 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr5_-_33892118 0.99 ENST00000515401.1
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr17_+_18625336 0.98 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L
tripartite motif containing 16-like
chr17_-_73266616 0.98 ENST00000579194.1
ENST00000581777.1
MIF4GD
MIF4G domain containing
chr2_+_101437487 0.98 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr17_+_67498295 0.98 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_10748019 0.97 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
SYCP2L
TMEM14B
synaptonemal complex protein 2-like
transmembrane protein 14B
chr17_-_76220740 0.96 ENST00000600484.1
AC087645.1
Uncharacterized protein
chr4_-_141348999 0.96 ENST00000325617.5
CLGN
calmegin
chr17_-_41623716 0.94 ENST00000319349.5
ETV4
ets variant 4
chr3_-_148939835 0.93 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr1_-_244006528 0.93 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr11_+_31833939 0.92 ENST00000530348.1
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr1_+_240408560 0.92 ENST00000441342.1
ENST00000545751.1
FMN2
formin 2
chr13_+_28527647 0.91 ENST00000567234.1
LINC00543
long intergenic non-protein coding RNA 543
chr6_+_10747986 0.90 ENST00000379542.5
TMEM14B
transmembrane protein 14B
chr2_-_190445499 0.89 ENST00000261024.2
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr17_+_27895609 0.88 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr17_-_41623691 0.87 ENST00000545954.1
ETV4
ets variant 4
chr15_-_34502278 0.86 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1
katanin p80 subunit B-like 1
chr12_+_54410664 0.85 ENST00000303406.4
HOXC4
homeobox C4
chr20_+_42574317 0.84 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr12_+_7169887 0.84 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr10_-_94301107 0.84 ENST00000436178.1
IDE
insulin-degrading enzyme
chr12_+_53662073 0.83 ENST00000553219.1
ENST00000257934.4
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr17_-_46667628 0.83 ENST00000498678.1
HOXB3
homeobox B3
chr5_-_33892046 0.82 ENST00000352040.3
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr7_+_134832808 0.82 ENST00000275767.3
TMEM140
transmembrane protein 140
chr22_-_40929812 0.81 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr17_+_46918925 0.79 ENST00000502761.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr6_-_152958521 0.77 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_153917700 0.76 ENST00000368646.2
DENND4B
DENN/MADD domain containing 4B
chr12_-_8088773 0.75 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr12_+_53662110 0.75 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr7_-_14026123 0.75 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr1_-_244013384 0.74 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr3_+_12392971 0.73 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr10_+_11784360 0.72 ENST00000379215.4
ENST00000420401.1
ECHDC3
enoyl CoA hydratase domain containing 3
chr10_+_35484793 0.71 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr6_+_131521120 0.71 ENST00000537868.1
AKAP7
A kinase (PRKA) anchor protein 7
chr8_-_124408652 0.70 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr9_-_16728161 0.69 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr9_-_98189055 0.69 ENST00000433644.2
RP11-435O5.2
RP11-435O5.2
chr5_+_32711419 0.68 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr4_+_183370146 0.67 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr15_-_72563585 0.66 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr9_+_133569108 0.65 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
EXOSC2
exosome component 2
chr14_-_103434869 0.65 ENST00000559043.1
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr2_-_176046391 0.63 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr2_+_27440229 0.63 ENST00000264705.4
ENST00000403525.1
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr3_-_64673289 0.62 ENST00000295903.4
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr15_+_48413169 0.59 ENST00000341459.3
ENST00000482911.2
SLC24A5
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr12_-_8088871 0.59 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr12_+_79258547 0.59 ENST00000457153.2
SYT1
synaptotagmin I
chr6_+_10723148 0.58 ENST00000541412.1
ENST00000229563.5
TMEM14C
transmembrane protein 14C
chr12_+_79258444 0.58 ENST00000261205.4
SYT1
synaptotagmin I
chr16_-_73082274 0.57 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr4_+_96012614 0.57 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr3_-_64673668 0.56 ENST00000498707.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr7_+_134671234 0.56 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
AGBL3
ATP/GTP binding protein-like 3
chr2_-_190446738 0.56 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr3_-_119396193 0.56 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17
COX17 cytochrome c oxidase copper chaperone
chr12_-_54652060 0.56 ENST00000552562.1
CBX5
chromobox homolog 5
chr5_+_32711829 0.56 ENST00000415167.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr14_-_20774092 0.55 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
TTC5
tetratricopeptide repeat domain 5
chr20_-_4229721 0.55 ENST00000379453.4
ADRA1D
adrenoceptor alpha 1D
chr5_-_140013275 0.55 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr17_+_12569306 0.54 ENST00000425538.1
MYOCD
myocardin
chr4_-_40632140 0.54 ENST00000514782.1
RBM47
RNA binding motif protein 47
chr14_+_93651358 0.52 ENST00000415050.2
TMEM251
transmembrane protein 251
chr8_+_11561660 0.52 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA4
GATA binding protein 4
chr8_-_122653630 0.52 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr20_-_22559211 0.51 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr2_+_135011731 0.51 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr2_-_96926313 0.51 ENST00000435268.1
TMEM127
transmembrane protein 127
chr2_+_145780725 0.51 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chr17_-_26695013 0.50 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr1_+_90286562 0.50 ENST00000525774.1
ENST00000337338.5
LRRC8D
leucine rich repeat containing 8 family, member D
chr14_+_93651296 0.49 ENST00000283534.4
ENST00000557574.1
TMEM251
RP11-371E8.4
transmembrane protein 251
Uncharacterized protein
chr5_+_71475449 0.48 ENST00000504492.1
MAP1B
microtubule-associated protein 1B
chr8_+_86121448 0.48 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr20_+_43160458 0.48 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr7_-_130066571 0.47 ENST00000492389.1
CEP41
centrosomal protein 41kDa
chr3_+_69915363 0.46 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr1_+_161691353 0.46 ENST00000367948.2
FCRLB
Fc receptor-like B
chr5_+_75699040 0.46 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr7_+_150076406 0.46 ENST00000329630.5
ZNF775
zinc finger protein 775
chr15_+_48413211 0.46 ENST00000449382.2
SLC24A5
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr12_-_111180644 0.45 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
chr6_+_26156551 0.45 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr2_-_55237484 0.45 ENST00000394609.2
RTN4
reticulon 4
chr17_+_67498396 0.45 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chrX_+_47077680 0.44 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr4_-_13546632 0.44 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chr5_-_37371163 0.44 ENST00000513532.1
NUP155
nucleoporin 155kDa
chr19_+_24009879 0.44 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr14_+_31494841 0.44 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr2_+_109237717 0.44 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_-_3595181 0.43 ENST00000552050.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr5_+_75699149 0.43 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr2_+_67624430 0.43 ENST00000272342.5
ETAA1
Ewing tumor-associated antigen 1
chr11_+_100784231 0.43 ENST00000531183.1
ARHGAP42
Rho GTPase activating protein 42
chr7_-_7782204 0.43 ENST00000418534.2
AC007161.5
AC007161.5
chr22_-_33968239 0.42 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr5_-_142780280 0.42 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_8198636 0.42 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chrX_+_70364667 0.42 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr17_+_12626199 0.42 ENST00000609971.1
AC005358.1
AC005358.1
chr8_-_38126675 0.42 ENST00000531823.1
ENST00000534339.1
ENST00000524616.1
ENST00000422581.2
ENST00000424479.2
ENST00000419686.2
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr7_-_121944491 0.41 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr2_-_40657397 0.41 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_-_44818599 0.40 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr9_+_133589333 0.40 ENST00000372348.2
ENST00000393293.4
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr14_+_31494672 0.40 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr10_-_21463116 0.40 ENST00000417816.2
NEBL
nebulette
chr12_-_110883346 0.40 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr17_+_57274914 0.39 ENST00000582004.1
ENST00000577660.1
PRR11
CTD-2510F5.6
proline rich 11
Uncharacterized protein
chr6_-_107077347 0.39 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chr5_-_54523143 0.39 ENST00000513312.1
MCIDAS
multiciliate differentiation and DNA synthesis associated cell cycle protein
chr3_+_69788576 0.38 ENST00000352241.4
ENST00000448226.2
MITF
microphthalmia-associated transcription factor
chr12_-_57039739 0.38 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr4_-_40632605 0.37 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr11_+_63742050 0.37 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr12_-_122018346 0.37 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr8_+_76452097 0.37 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr15_+_36887069 0.37 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr3_+_69985734 0.36 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr1_-_31661000 0.36 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr17_-_73775839 0.36 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr1_-_17676070 0.35 ENST00000602074.1
AC004824.2
Uncharacterized protein
chr16_+_21608525 0.35 ENST00000567404.1
METTL9
methyltransferase like 9
chr3_-_50360165 0.35 ENST00000428028.1
HYAL2
hyaluronoglucosaminidase 2
chr16_+_3068393 0.35 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr14_+_23938891 0.34 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
NGDN
neuroguidin, EIF4E binding protein
chr7_-_14026063 0.34 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr17_-_26694979 0.34 ENST00000438614.1
VTN
vitronectin
chr1_+_178994939 0.34 ENST00000440702.1
FAM20B
family with sequence similarity 20, member B
chr5_-_37371278 0.34 ENST00000231498.3
NUP155
nucleoporin 155kDa
chr16_-_69788816 0.34 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr2_+_207630081 0.34 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr1_+_165864800 0.33 ENST00000469256.2
UCK2
uridine-cytidine kinase 2
chr19_-_633576 0.33 ENST00000588649.2
POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr17_-_7991021 0.32 ENST00000319144.4
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr17_-_3595042 0.32 ENST00000552723.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr10_-_73848531 0.32 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_+_141106643 0.32 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr19_+_36203830 0.31 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr15_-_34502197 0.31 ENST00000557877.1
KATNBL1
katanin p80 subunit B-like 1
chr2_+_29001711 0.30 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr12_-_58220078 0.30 ENST00000549039.1
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr16_-_10652993 0.30 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr12_-_58135903 0.30 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr3_+_69915385 0.30 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr1_+_225600404 0.29 ENST00000366845.2
AC092811.1
AC092811.1
chr16_-_18911366 0.29 ENST00000565224.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr17_-_47925379 0.29 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr15_+_31196080 0.29 ENST00000561607.1
ENST00000565466.1
FAN1
FANCD2/FANCI-associated nuclease 1
chrX_-_128657457 0.29 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr2_+_177015950 0.29 ENST00000306324.3
HOXD4
homeobox D4
chr10_-_73848764 0.29 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_-_43147549 0.28 ENST00000344697.2
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr8_+_77593448 0.28 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr5_-_140013224 0.28 ENST00000498971.2
CD14
CD14 molecule
chr15_+_58702742 0.28 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr7_-_107443652 0.28 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr20_-_30310797 0.28 ENST00000422920.1
BCL2L1
BCL2-like 1
chr13_+_110958124 0.27 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr2_-_231989808 0.27 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr6_+_28249332 0.27 ENST00000259883.3
PGBD1
piggyBac transposable element derived 1
chr6_+_28249299 0.27 ENST00000405948.2
PGBD1
piggyBac transposable element derived 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:2001113 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
1.0 3.1 GO:1903217 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.7 4.4 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.6 2.3 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.5 1.5 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.4 1.6 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.3 1.0 GO:0090427 activation of meiosis(GO:0090427)
0.3 1.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.3 1.3 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3 0.9 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.3 2.6 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.3 1.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 1.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 1.9 GO:0021546 rhombomere development(GO:0021546)
0.2 1.5 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.2 0.8 GO:1901143 insulin catabolic process(GO:1901143)
0.2 0.6 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 0.8 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 1.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.8 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 0.6 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 0.7 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 1.2 GO:0035989 tendon development(GO:0035989)
0.1 0.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.0 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.8 GO:0070295 renal water absorption(GO:0070295)
0.1 0.4 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.1 0.5 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.6 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 1.0 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.7 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.4 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.3 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.8 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.5 GO:0006825 copper ion transport(GO:0006825)
0.1 1.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 1.0 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 1.7 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.3 GO:0042176 regulation of protein catabolic process(GO:0042176)
0.0 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.9 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:1903980 positive regulation of microglial cell activation(GO:1903980)
0.0 1.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 1.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.7 GO:0097264 self proteolysis(GO:0097264)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.4 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.3 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.5 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.3 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.3 GO:0003093 regulation of glomerular filtration(GO:0003093)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.0 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.4 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:1904018 positive regulation of vasculature development(GO:1904018)
0.0 0.1 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0044753 amphisome(GO:0044753)
0.4 1.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 2.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.9 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 2.6 GO:0072562 blood microparticle(GO:0072562)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.0 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.5 1.5 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.5 4.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.5 1.5 GO:0097689 iron channel activity(GO:0097689)
0.3 0.8 GO:0031626 beta-endorphin binding(GO:0031626)
0.3 1.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 1.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 2.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.6 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 1.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 2.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 1.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.6 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.8 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.6 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.4 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 2.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.7 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.3 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.1 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.6 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 1.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 3.0 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 3.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis