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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR2E3

Z-value: 1.01

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Transcription factors associated with NR2E3

Gene Symbol Gene ID Gene Info
ENSG00000031544.10 nuclear receptor subfamily 2 group E member 3

Activity profile of NR2E3 motif

Sorted Z-values of NR2E3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_138210919 3.09 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr4_+_174089951 2.60 ENST00000512285.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr5_+_179135246 1.63 ENST00000508787.1
calnexin
chr17_+_57233087 1.31 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
proline rich 11
chr12_+_41221794 1.27 ENST00000547849.1
contactin 1
chr2_+_172309634 1.25 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr11_-_73471655 1.23 ENST00000400470.2
RAB6A, member RAS oncogene family
chr3_+_69915363 1.20 ENST00000451708.1
microphthalmia-associated transcription factor
chr1_+_12042015 1.14 ENST00000412236.1
mitofusin 2
chr3_+_141043050 1.14 ENST00000509842.1
zinc finger and BTB domain containing 38
chr10_-_14596140 1.10 ENST00000496330.1
family with sequence similarity 107, member B
chr3_+_184033551 1.08 ENST00000456033.1
eukaryotic translation initiation factor 4 gamma, 1
chr8_+_38677850 1.08 ENST00000518809.1
ENST00000520611.1
transforming, acidic coiled-coil containing protein 1
chr3_+_141105705 1.08 ENST00000513258.1
zinc finger and BTB domain containing 38
chr4_+_174089904 1.07 ENST00000265000.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr13_+_76378357 1.06 ENST00000489941.2
ENST00000525373.1
LIM domain 7
chr11_+_57559005 1.05 ENST00000534647.1
catenin (cadherin-associated protein), delta 1
chr2_-_197664366 1.03 ENST00000409364.3
ENST00000263956.3
general transcription factor IIIC, polypeptide 3, 102kDa
chr13_+_76334498 1.02 ENST00000534657.1
LIM domain 7
chr6_-_108278456 1.00 ENST00000429168.1
SEC63 homolog (S. cerevisiae)
chr7_-_124569991 1.00 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
protection of telomeres 1
chr4_+_71859156 1.00 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
deoxycytidine kinase
chr17_+_57232690 0.99 ENST00000262293.4
proline rich 11
chr15_+_45879964 0.99 ENST00000565409.1
ENST00000564765.1
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr2_-_65593784 0.99 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr4_-_40477766 0.98 ENST00000507180.1
RNA binding motif protein 47
chr5_-_16738451 0.98 ENST00000274203.9
ENST00000515803.1
myosin X
chr6_-_101329191 0.97 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr3_+_69915385 0.96 ENST00000314589.5
microphthalmia-associated transcription factor
chr4_+_169633310 0.96 ENST00000510998.1
palladin, cytoskeletal associated protein
chr2_-_208031943 0.96 ENST00000421199.1
ENST00000457962.1
Kruppel-like factor 7 (ubiquitous)
chr1_-_154150651 0.96 ENST00000302206.5
tropomyosin 3
chr12_+_41221975 0.95 ENST00000552913.1
contactin 1
chr10_-_91403625 0.95 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
pantothenate kinase 1
chr3_-_33686925 0.95 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
cytoplasmic linker associated protein 2
chr19_-_14628645 0.94 ENST00000598235.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chrX_-_138914394 0.93 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATPase, class VI, type 11C
chr4_+_170581213 0.93 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr5_-_59783882 0.92 ENST00000505507.2
ENST00000502484.2
phosphodiesterase 4D, cAMP-specific
chr11_+_121447469 0.92 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr4_-_39367949 0.92 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr21_-_16374688 0.91 ENST00000411932.1
nuclear receptor interacting protein 1
chr10_-_93392811 0.88 ENST00000238994.5
protein phosphatase 1, regulatory subunit 3C
chr18_+_55712915 0.87 ENST00000592846.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr5_+_133861339 0.87 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
jade family PHD finger 2
chr16_+_23690138 0.84 ENST00000300093.4
polo-like kinase 1
chr3_+_141105235 0.84 ENST00000503809.1
zinc finger and BTB domain containing 38
chr5_-_148930731 0.84 ENST00000515748.2
casein kinase 1, alpha 1
chr2_+_160590469 0.83 ENST00000409591.1
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr19_-_14628234 0.83 ENST00000595139.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr16_+_19619083 0.80 ENST00000538552.1
chromosome 16 open reading frame 62
chr7_-_124569864 0.79 ENST00000609702.1
protection of telomeres 1
chr11_-_47521309 0.79 ENST00000535982.1
CUGBP, Elav-like family member 1
chr5_-_150473127 0.79 ENST00000521001.1
TNFAIP3 interacting protein 1
chr2_+_187454749 0.78 ENST00000261023.3
ENST00000374907.3
integrin, alpha V
chr2_-_178128250 0.78 ENST00000448782.1
ENST00000446151.2
nuclear factor, erythroid 2-like 2
chr1_+_61547405 0.77 ENST00000371189.4
nuclear factor I/A
chr1_+_203595689 0.76 ENST00000357681.5
ATPase, Ca++ transporting, plasma membrane 4
chr3_+_186501979 0.75 ENST00000498746.1
eukaryotic translation initiation factor 4A2
chr3_-_189839467 0.75 ENST00000426003.1
leprecan-like 1
chr17_+_46189311 0.75 ENST00000582481.1
sorting nexin 11
chr6_+_74405501 0.75 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr4_-_25865159 0.74 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_-_208031542 0.73 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr18_-_66382289 0.72 ENST00000443099.2
ENST00000562706.1
ENST00000544714.2
thioredoxin-related transmembrane protein 3
chr12_+_104680793 0.70 ENST00000529546.1
ENST00000529751.1
ENST00000540716.1
ENST00000528079.2
ENST00000526580.1
thioredoxin reductase 1
chr2_+_24150180 0.69 ENST00000404924.1
UBX domain protein 2A
chr11_-_122930121 0.69 ENST00000524552.1
heat shock 70kDa protein 8
chr6_-_131291572 0.69 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chrX_+_114874727 0.69 ENST00000543070.1
plastin 3
chr4_+_169418255 0.68 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr17_+_46185111 0.68 ENST00000582104.1
ENST00000584335.1
sorting nexin 11
chr2_-_178128149 0.68 ENST00000423513.1
nuclear factor, erythroid 2-like 2
chr22_-_40929812 0.68 ENST00000422851.1
megakaryoblastic leukemia (translocation) 1
chr16_+_30773610 0.67 ENST00000566811.1
ring finger protein 40, E3 ubiquitin protein ligase
chr16_-_66785497 0.67 ENST00000440564.2
ENST00000379482.2
ENST00000443351.2
ENST00000566150.1
dynein, cytoplasmic 1, light intermediate chain 2
chr12_+_53773944 0.67 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chr5_+_102455853 0.67 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
diphosphoinositol pentakisphosphate kinase 2
chr2_-_225434538 0.66 ENST00000409096.1
cullin 3
chr1_-_179834311 0.66 ENST00000553856.1
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr2_-_220252530 0.66 ENST00000521459.1
aspartyl aminopeptidase
chr10_-_115904361 0.65 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chr10_-_104866395 0.65 ENST00000458345.1
5'-nucleotidase, cytosolic II
chr2_+_102456277 0.64 ENST00000421882.1
mitogen-activated protein kinase kinase kinase kinase 4
chr8_+_54764346 0.64 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr13_+_76378407 0.64 ENST00000447038.1
LIM domain 7
chrX_+_123094672 0.63 ENST00000354548.5
ENST00000458700.1
stromal antigen 2
chr11_-_122929699 0.63 ENST00000526686.1
heat shock 70kDa protein 8
chr17_-_1463095 0.63 ENST00000575895.1
ENST00000573056.1
phosphatidylinositol transfer protein, alpha
chr12_+_96588279 0.63 ENST00000552142.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr11_-_102962874 0.63 ENST00000531543.1
DCN1, defective in cullin neddylation 1, domain containing 5
chr17_-_49124230 0.63 ENST00000510283.1
ENST00000510855.1
sperm associated antigen 9
chr6_+_37897735 0.62 ENST00000373389.5
zinc finger, AN1-type domain 3
chr4_+_160188306 0.62 ENST00000510510.1
Rap guanine nucleotide exchange factor (GEF) 2
chr3_-_46000146 0.61 ENST00000438446.1
FYVE and coiled-coil domain containing 1
chr2_-_220252068 0.61 ENST00000430206.1
ENST00000429013.1
aspartyl aminopeptidase
chr3_-_196159268 0.61 ENST00000381887.3
ENST00000535858.1
ENST00000428095.1
ENST00000296328.4
UBX domain protein 7
chr15_+_73976715 0.61 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276 molecule
chr12_-_110906027 0.60 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN-loop GTPase 3
chr14_+_73525265 0.60 ENST00000525161.1
RNA binding motif protein 25
chr3_-_33686743 0.59 ENST00000333778.6
ENST00000539981.1
cytoplasmic linker associated protein 2
chr3_-_138312971 0.59 ENST00000485115.1
ENST00000484888.1
ENST00000468900.1
ENST00000542237.1
ENST00000481834.1
centrosomal protein 70kDa
chr1_-_47131521 0.59 ENST00000542495.1
ENST00000532925.1
ATP synthase mitochondrial F1 complex assembly factor 1
chr1_+_24118452 0.58 ENST00000421070.1
lysophospholipase II
chr3_+_189507523 0.57 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chr20_-_40247133 0.57 ENST00000373233.3
ENST00000309279.7
chromodomain helicase DNA binding protein 6
chr11_+_100784231 0.56 ENST00000531183.1
Rho GTPase activating protein 42
chr1_+_41448820 0.56 ENST00000372616.1
CTP synthase 1
chr1_-_184723701 0.56 ENST00000367512.3
ER degradation enhancer, mannosidase alpha-like 3
chr4_-_152147579 0.56 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3 domain containing 19
chr14_+_67831576 0.55 ENST00000555876.1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr7_-_103848405 0.55 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
origin recognition complex, subunit 5
chr14_-_35099377 0.55 ENST00000362031.4
sorting nexin 6
chr3_-_65583561 0.54 ENST00000460329.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr2_-_37544209 0.54 ENST00000234179.2
protein kinase D3
chr20_-_56286479 0.53 ENST00000265626.4
prostate transmembrane protein, androgen induced 1
chr6_-_4135693 0.53 ENST00000495548.1
ENST00000380125.2
ENST00000465828.1
enoyl-CoA delta isomerase 2
chr6_+_126221034 0.53 ENST00000433571.1
nuclear receptor coactivator 7
chr3_+_164924716 0.53 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
chr5_-_65018834 0.52 ENST00000506816.1
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr19_+_30433372 0.52 ENST00000312051.6
URI1, prefoldin-like chaperone
chr11_+_71640071 0.52 ENST00000533380.1
ENST00000393713.3
ENST00000545854.1
ring finger protein 121
chrX_-_39956656 0.52 ENST00000397354.3
ENST00000378444.4
BCL6 corepressor
chr15_+_65914347 0.52 ENST00000544319.2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr11_+_74204883 0.51 ENST00000528481.1
polymerase (DNA-directed), delta 3, accessory subunit
chr9_+_91605778 0.51 ENST00000375851.2
ENST00000375850.3
ENST00000334490.5
chromosome 9 open reading frame 47
chrX_-_30993201 0.51 ENST00000288422.2
ENST00000378932.2
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr3_-_133380731 0.51 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr13_+_76362974 0.51 ENST00000497947.2
LIM domain 7
chr2_+_33359687 0.51 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr2_+_121493717 0.51 ENST00000418323.1
GLI family zinc finger 2
chr6_+_4776580 0.51 ENST00000397588.3
chromodomain protein, Y-like
chr15_+_59908633 0.50 ENST00000559626.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_-_217804377 0.50 ENST00000366935.3
ENST00000366934.3
G patch domain containing 2
chr14_+_69658480 0.50 ENST00000409949.1
ENST00000409242.1
ENST00000312994.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr2_+_7073174 0.50 ENST00000416587.1
ring finger protein 144A
chr11_-_8795787 0.50 ENST00000528196.1
ENST00000533681.1
suppression of tumorigenicity 5
chr11_-_10822029 0.49 ENST00000528839.1
eukaryotic translation initiation factor 4 gamma, 2
chr19_+_47421933 0.48 ENST00000404338.3
Rho GTPase activating protein 35
chrX_+_123097014 0.48 ENST00000394478.1
stromal antigen 2
chr18_+_23806382 0.48 ENST00000400466.2
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr11_-_102962929 0.48 ENST00000260247.5
DCN1, defective in cullin neddylation 1, domain containing 5
chr5_+_34757309 0.48 ENST00000397449.1
retinoic acid induced 14
chr5_-_137368726 0.48 ENST00000420893.2
ENST00000425075.2
family with sequence similarity 13, member B
chr1_+_84629976 0.48 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_68255912 0.48 ENST00000262215.3
ENST00000519436.1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr5_+_102200948 0.48 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
peptidylglycine alpha-amidating monooxygenase
chr12_+_10658489 0.47 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr14_+_54976603 0.47 ENST00000557317.1
cell growth regulator with ring finger domain 1
chr18_+_19321281 0.47 ENST00000261537.6
mindbomb E3 ubiquitin protein ligase 1
chr15_+_57211318 0.46 ENST00000557947.1
transcription factor 12
chr17_-_47786375 0.46 ENST00000511657.1
solute carrier family 35, member B1
chr17_-_41977964 0.46 ENST00000377184.3
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr1_+_156084461 0.46 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr1_+_61330931 0.46 ENST00000371191.1
nuclear factor I/A
chr8_-_72987810 0.45 ENST00000262209.4
transient receptor potential cation channel, subfamily A, member 1
chr5_+_68788594 0.45 ENST00000396442.2
ENST00000380766.2
occludin
chr6_-_4135825 0.45 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
enoyl-CoA delta isomerase 2
chr15_-_52587945 0.45 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
myosin VC
chr4_-_146859623 0.45 ENST00000379448.4
ENST00000513320.1
zinc finger protein 827
chr8_+_107460147 0.45 ENST00000442977.2
oxidation resistance 1
chr2_-_45795145 0.44 ENST00000535761.1
S1 RNA binding domain 1
chr15_-_77197620 0.44 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
S-phase cyclin A-associated protein in the ER
chr12_-_57146095 0.44 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr16_+_21623392 0.44 ENST00000562961.1
methyltransferase like 9
chr17_-_40575535 0.44 ENST00000357037.5
polymerase I and transcript release factor
chr2_+_33359646 0.44 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr4_+_159727272 0.44 ENST00000379346.3
folliculin interacting protein 2
chr2_+_201987200 0.44 ENST00000425030.1
CASP8 and FADD-like apoptosis regulator
chr13_-_48575376 0.44 ENST00000434484.1
succinate-CoA ligase, ADP-forming, beta subunit
chr2_+_33359473 0.44 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr13_-_48575401 0.43 ENST00000433022.1
ENST00000544100.1
succinate-CoA ligase, ADP-forming, beta subunit
chr1_+_203595903 0.43 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATPase, Ca++ transporting, plasma membrane 4
chr12_+_78359999 0.43 ENST00000550503.1
neuron navigator 3
chr1_-_38156153 0.43 ENST00000464085.1
ENST00000486637.1
ENST00000358011.4
ENST00000461359.1
chromosome 1 open reading frame 109
chr3_+_50654821 0.43 ENST00000457064.1
mitogen-activated protein kinase-activated protein kinase 3
chr12_-_76477707 0.43 ENST00000551992.1
nucleosome assembly protein 1-like 1
chr2_-_175711978 0.43 ENST00000409089.2
chimerin 1
chr16_+_50300427 0.42 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
adenylate cyclase 7
chr3_-_33700589 0.42 ENST00000461133.3
ENST00000496954.2
cytoplasmic linker associated protein 2
chr20_-_20033052 0.42 ENST00000536226.1
crooked neck pre-mRNA splicing factor 1
chr8_+_101170563 0.42 ENST00000520508.1
ENST00000388798.2
sperm associated antigen 1
chr6_+_12008986 0.42 ENST00000491710.1
human immunodeficiency virus type I enhancer binding protein 1
chr9_-_112260531 0.42 ENST00000374541.2
ENST00000262539.3
protein tyrosine phosphatase, non-receptor type 3
chr14_+_24584372 0.42 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DDB1 and CUL4 associated factor 11
chr14_+_90422239 0.41 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
tyrosyl-DNA phosphodiesterase 1
chr4_+_159727222 0.41 ENST00000512986.1
folliculin interacting protein 2
chr1_-_155904161 0.41 ENST00000368319.3
KIAA0907
chr14_-_35099315 0.41 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
sorting nexin 6
chr4_-_76555657 0.41 ENST00000307465.4
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr1_+_65775204 0.41 ENST00000371069.4
DnaJ (Hsp40) homolog, subfamily C, member 6
chr16_-_69390209 0.41 ENST00000563634.1
Uncharacterized protein
chr17_-_15554940 0.40 ENST00000455584.2
Uncharacterized protein
chr11_+_71640112 0.40 ENST00000530137.1
ring finger protein 121
chr16_+_53483983 0.40 ENST00000544545.1
retinoblastoma-like 2 (p130)
chr3_-_185641681 0.40 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr8_+_132952112 0.40 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr15_+_79165222 0.40 ENST00000559930.1
mortality factor 4 like 1
chr14_-_75083313 0.39 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr6_+_4021554 0.39 ENST00000337659.6
pre-mRNA processing factor 4B

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.6 1.8 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.4 1.2 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.3 1.0 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 0.9 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3 0.9 GO:0001543 ovarian follicle rupture(GO:0001543)
0.3 1.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.3 1.3 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.3 1.8 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.2 1.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 0.8 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.2 1.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.2 0.7 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 0.5 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 1.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 0.8 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 1.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.6 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 2.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 2.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.6 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.7 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 1.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.5 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.8 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 0.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.0 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 1.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 1.0 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.5 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.4 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.5 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 1.0 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.7 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.9 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.9 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.7 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 1.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1 0.3 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.5 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 1.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.4 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.5 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 1.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 1.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.4 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 1.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:1901490 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) regulation of lymphangiogenesis(GO:1901490)
0.1 1.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 1.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 1.0 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 0.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.5 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.4 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 2.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 1.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0072095 regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.0 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 2.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.5 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.4 GO:0044351 macropinocytosis(GO:0044351)
0.0 1.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.8 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 3.5 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.7 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0015888 thiamine transport(GO:0015888)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 1.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 1.0 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.8 GO:0016246 RNA interference(GO:0016246)
0.0 0.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.7 GO:0009642 response to light intensity(GO:0009642)
0.0 0.4 GO:0007548 sex differentiation(GO:0007548)
0.0 0.4 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.8 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 1.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 1.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.7 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.8 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 1.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 1.0 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 3.1 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034686 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.2 1.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 1.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 0.6 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.2 3.1 GO:0016600 flotillin complex(GO:0016600)
0.1 2.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 1.0 GO:0097422 tubular endosome(GO:0097422)
0.1 0.4 GO:0034455 t-UTP complex(GO:0034455)
0.1 1.0 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.8 GO:0070187 telosome(GO:0070187)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0005715 late recombination nodule(GO:0005715)
0.1 0.9 GO:0033503 HULC complex(GO:0033503)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 1.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 1.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.4 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 0.2 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.0 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0005638 lamin filament(GO:0005638)
0.0 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 1.0 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.7 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 1.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.1 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 1.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.7 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 3.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0005602 complement component C1 complex(GO:0005602)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 4.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 3.1 GO:0043209 myelin sheath(GO:0043209)
0.0 2.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.4 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 1.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 1.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.3 1.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2 1.4 GO:0050436 microfibril binding(GO:0050436)
0.2 0.6 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.2 1.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 0.7 GO:0003896 DNA primase activity(GO:0003896)
0.2 0.9 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.2 1.0 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 0.5 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 1.0 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.2 0.6 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.7 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.7 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 3.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.5 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.8 GO:0042835 BRE binding(GO:0042835)
0.1 1.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.7 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 3.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.0 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 3.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.1 0.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 1.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.2 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.3 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 2.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.0 GO:0034452 dynactin binding(GO:0034452)
0.1 0.2 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.7 GO:0042731 PH domain binding(GO:0042731)
0.1 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 2.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 2.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 2.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.5 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0002020 protease binding(GO:0002020)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 3.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 3.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 3.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 4.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.0 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 4.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 4.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling