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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR4A1

Z-value: 0.77

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.15 nuclear receptor subfamily 4 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A1hg19_v2_chr12_+_52445191_524452430.785.5e-05Click!

Activity profile of NR4A1 motif

Sorted Z-values of NR4A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_101542462 4.40 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr9_-_75567962 4.07 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr17_+_4854375 3.25 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr16_+_81272287 2.95 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr17_+_4855053 2.37 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr12_-_53320245 2.34 ENST00000552150.1
KRT8
keratin 8
chr2_+_175199674 2.28 ENST00000394967.2
SP9
Sp9 transcription factor
chrX_+_2746850 2.22 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2
chr11_+_66624527 2.06 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr12_+_109577202 1.96 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr19_+_6372444 1.92 ENST00000245812.3
ALKBH7
alkB, alkylation repair homolog 7 (E. coli)
chr1_+_66820058 1.86 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr17_+_9745786 1.77 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr11_+_7618413 1.64 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_+_691792 1.37 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr12_+_21679220 1.34 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr10_-_33625154 1.24 ENST00000265371.4
NRP1
neuropilin 1
chr4_-_40632844 1.20 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr17_+_7123207 1.18 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr22_-_51017084 1.17 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr22_-_51016846 1.17 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr10_+_35484793 1.17 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr19_-_41256207 1.16 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr12_+_54378923 1.08 ENST00000303460.4
HOXC10
homeobox C10
chr7_-_37488834 1.03 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chrX_+_2746818 1.02 ENST00000398806.3
GYG2
glycogenin 2
chr12_+_58335360 0.97 ENST00000300145.3
XRCC6BP1
XRCC6 binding protein 1
chr14_+_32476072 0.95 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr17_-_79283041 0.90 ENST00000332012.5
LINC00482
long intergenic non-protein coding RNA 482
chr17_+_79670386 0.89 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr14_-_77495007 0.89 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr7_-_37488777 0.88 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chr9_+_36572851 0.85 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr4_+_176986978 0.81 ENST00000508596.1
ENST00000393643.2
WDR17
WD repeat domain 17
chr2_+_26568965 0.80 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr14_-_35591433 0.80 ENST00000261475.5
ENST00000555644.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr11_+_86748863 0.78 ENST00000340353.7
TMEM135
transmembrane protein 135
chr14_-_35591156 0.78 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr17_+_41150290 0.76 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr14_-_21566731 0.72 ENST00000360947.3
ZNF219
zinc finger protein 219
chr17_-_66287257 0.71 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr9_+_137987825 0.70 ENST00000545657.1
OLFM1
olfactomedin 1
chr19_+_4153598 0.69 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr12_+_49687425 0.69 ENST00000257860.4
PRPH
peripherin
chr6_-_152958521 0.67 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr2_+_178257372 0.66 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr9_-_139137648 0.66 ENST00000358701.5
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr12_+_54378849 0.65 ENST00000515593.1
HOXC10
homeobox C10
chr19_-_11639931 0.64 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr4_-_40632140 0.62 ENST00000514782.1
RBM47
RNA binding motif protein 47
chr8_-_92053212 0.60 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr14_+_38065052 0.59 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr2_+_27282134 0.59 ENST00000441931.1
AGBL5
ATP/GTP binding protein-like 5
chr5_-_142784003 0.58 ENST00000416954.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr19_-_11639910 0.56 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr6_-_152489484 0.54 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr3_-_117716418 0.53 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr12_+_93963590 0.52 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr8_+_19536083 0.51 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr10_+_26986582 0.51 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr2_-_44223138 0.51 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr17_+_41150793 0.50 ENST00000586277.1
RPL27
ribosomal protein L27
chr20_+_11898507 0.50 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr5_-_27038683 0.48 ENST00000511822.1
ENST00000231021.4
CDH9
cadherin 9, type 2 (T1-cadherin)
chr6_-_116381918 0.47 ENST00000606080.1
FRK
fyn-related kinase
chr15_+_36887069 0.45 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr8_+_99956662 0.45 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr17_+_1646130 0.41 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr7_-_107443652 0.40 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr1_+_156589051 0.40 ENST00000255039.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr17_-_7123021 0.38 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr8_-_92053042 0.38 ENST00000520014.1
TMEM55A
transmembrane protein 55A
chr15_+_75335604 0.37 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr14_-_21567009 0.35 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr4_-_111563076 0.35 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr17_-_7307358 0.35 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chrX_-_54824673 0.33 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr19_+_17416457 0.32 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chr7_-_105516923 0.32 ENST00000478915.1
ATXN7L1
ataxin 7-like 1
chr19_+_45394477 0.32 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr6_+_30749649 0.30 ENST00000422944.1
HCG20
HLA complex group 20 (non-protein coding)
chr4_-_40632881 0.29 ENST00000511598.1
RBM47
RNA binding motif protein 47
chr11_+_64073699 0.28 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr18_-_60986613 0.27 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr14_-_35591679 0.27 ENST00000557278.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr1_+_156589198 0.27 ENST00000456112.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr7_-_37488547 0.26 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr10_+_12110963 0.26 ENST00000263035.4
ENST00000437298.1
DHTKD1
dehydrogenase E1 and transketolase domain containing 1
chr4_+_71108300 0.25 ENST00000304954.3
CSN3
casein kappa
chr2_-_27603582 0.24 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr5_-_74162739 0.24 ENST00000513277.1
FAM169A
family with sequence similarity 169, member A
chr7_+_6048856 0.24 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr20_-_42815733 0.24 ENST00000342272.3
JPH2
junctophilin 2
chr10_-_69991865 0.23 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr17_+_7123125 0.23 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL
acyl-CoA dehydrogenase, very long chain
chr18_-_60986962 0.22 ENST00000333681.4
BCL2
B-cell CLL/lymphoma 2
chrX_+_33744503 0.22 ENST00000439992.1
RP11-305F18.1
RP11-305F18.1
chr20_-_44485835 0.22 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr15_-_41120896 0.22 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr17_-_38928414 0.22 ENST00000335552.4
KRT26
keratin 26
chr8_+_99956759 0.22 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr3_+_63638372 0.22 ENST00000496807.1
SNTN
sentan, cilia apical structure protein
chr12_-_16759711 0.21 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_-_130536774 0.21 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr6_+_133561725 0.20 ENST00000452339.2
EYA4
eyes absent homolog 4 (Drosophila)
chr1_+_173793777 0.20 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr10_-_75351088 0.20 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr6_+_118869452 0.19 ENST00000357525.5
PLN
phospholamban
chr10_-_128359074 0.19 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr7_-_81399438 0.18 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_+_212738676 0.18 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr12_+_21525818 0.17 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr11_-_113577014 0.17 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chr4_-_111563279 0.17 ENST00000511837.1
PITX2
paired-like homeodomain 2
chr7_+_99933730 0.16 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr12_+_50794891 0.16 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr11_-_8680383 0.16 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr10_-_74714533 0.16 ENST00000373032.3
PLA2G12B
phospholipase A2, group XIIB
chr11_-_113577052 0.16 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr5_-_53115506 0.15 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1
CTD-2081C10.1
chr11_+_278365 0.15 ENST00000534750.1
NLRP6
NLR family, pyrin domain containing 6
chr5_-_74162605 0.15 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr5_+_35852797 0.14 ENST00000508941.1
IL7R
interleukin 7 receptor
chr17_+_41150479 0.13 ENST00000589913.1
RPL27
ribosomal protein L27
chr16_+_21608525 0.13 ENST00000567404.1
METTL9
methyltransferase like 9
chr11_+_86748957 0.13 ENST00000526733.1
ENST00000532959.1
TMEM135
transmembrane protein 135
chr20_+_3052264 0.12 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr17_+_73629500 0.12 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr3_-_48936272 0.11 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr11_+_86748998 0.11 ENST00000525018.1
ENST00000355734.4
TMEM135
transmembrane protein 135
chr4_-_65275162 0.11 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr4_-_89744457 0.11 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr11_+_116700600 0.10 ENST00000227667.3
APOC3
apolipoprotein C-III
chr11_+_116700614 0.10 ENST00000375345.1
APOC3
apolipoprotein C-III
chr5_-_169626104 0.10 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1
CTB-27N1.1
chr6_+_31895287 0.09 ENST00000447952.2
C2
complement component 2
chr7_-_229557 0.09 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr14_+_101295948 0.09 ENST00000452514.2
MEG3
maternally expressed 3 (non-protein coding)
chrX_-_48823165 0.09 ENST00000419374.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr17_-_29624343 0.08 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr3_-_133648656 0.08 ENST00000408895.2
C3orf36
chromosome 3 open reading frame 36
chrX_-_108868390 0.07 ENST00000372101.2
KCNE1L
KCNE1-like
chr20_-_42816206 0.07 ENST00000372980.3
JPH2
junctophilin 2
chr5_-_142784101 0.07 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_+_44126545 0.07 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11
calpain 11
chr4_-_40632757 0.06 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr1_+_40713573 0.06 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr6_+_31895254 0.06 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr3_+_138340049 0.06 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr13_-_74993252 0.06 ENST00000325811.1
AL355390.1
Uncharacterized protein
chr5_+_127039075 0.05 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr16_+_53241854 0.04 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr6_+_64346386 0.04 ENST00000509330.1
PHF3
PHD finger protein 3
chr11_+_120971882 0.04 ENST00000392793.1
TECTA
tectorin alpha
chr7_-_81399287 0.04 ENST00000354224.6
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr19_+_54926601 0.04 ENST00000301194.4
TTYH1
tweety family member 1
chr2_-_25194963 0.03 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr4_-_89744314 0.03 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr7_-_81399411 0.03 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_135612198 0.02 ENST00000589735.1
LUZP6
leucine zipper protein 6
chr7_-_72936531 0.02 ENST00000339594.4
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr2_-_25194476 0.02 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr4_+_57253672 0.01 ENST00000602927.1
RP11-646I6.5
RP11-646I6.5
chr16_+_21312170 0.01 ENST00000338573.5
ENST00000561968.1
CRYM-AS1
CRYM antisense RNA 1
chr3_+_63638339 0.01 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr4_-_40632605 0.01 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr12_-_94673956 0.01 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.7 4.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 2.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.3 1.9 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.3 0.9 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 1.2 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 1.8 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.2 2.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.5 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 2.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.7 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 2.5 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.9 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 1.4 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 1.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.5 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.7 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 5.6 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 0.2 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 1.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 0.2 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.7 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 0.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 2.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.6 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925) positive regulation of penile erection(GO:0060406)
0.0 0.4 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 2.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.4 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 1.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.0 GO:0032094 response to food(GO:0032094)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 2.3 GO:0035113 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0021554 optic nerve development(GO:0021554)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 4.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.2 GO:0097443 sorting endosome(GO:0097443)
0.1 2.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.8 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.9 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.6 5.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 4.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 1.8 GO:0004967 glucagon receptor activity(GO:0004967)
0.3 2.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.3 0.9 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.3 2.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 4.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 1.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.0 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.4 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.1 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.5 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0015288 protein channel activity(GO:0015266) porin activity(GO:0015288)
0.0 2.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.9 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 4.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 5.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 4.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling