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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR6A1

Z-value: 0.75

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Transcription factors associated with NR6A1

Gene Symbol Gene ID Gene Info
NR6A1
ENSG00000148200.12 nuclear receptor subfamily 6 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR6A1hg19_v2_chr9_-_127358087_127358170-0.723.0e-04Click!

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_43803517 2.02 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr11_-_64764435 1.50 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr11_+_65190245 1.32 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr19_+_11455900 1.25 ENST00000588790.1
CCDC159
coiled-coil domain containing 159
chr6_+_62284008 1.21 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr15_-_41166414 1.14 ENST00000220507.4
RHOV
ras homolog family member V
chr6_-_43197189 1.12 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr8_-_145701718 1.05 ENST00000377317.4
FOXH1
forkhead box H1
chr7_-_95225768 1.04 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr6_-_25874440 1.02 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr19_-_6720686 1.02 ENST00000245907.6
C3
complement component 3
chr10_-_76995675 0.89 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr17_+_48712206 0.84 ENST00000427699.1
ENST00000285238.8
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr7_-_150777874 0.79 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr19_+_10197463 0.74 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr5_-_140027357 0.73 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr17_-_26903900 0.73 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr7_+_99933730 0.72 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr8_+_144349606 0.72 ENST00000521682.1
ENST00000340042.1
GLI4
GLI family zinc finger 4
chr16_+_67195592 0.71 ENST00000519378.1
FBXL8
F-box and leucine-rich repeat protein 8
chr3_-_114790179 0.70 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_176836577 0.70 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr8_+_144640477 0.69 ENST00000262580.4
GSDMD
gasdermin D
chr19_-_58864848 0.69 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr6_-_31138439 0.68 ENST00000259915.8
POU5F1
POU class 5 homeobox 1
chr19_+_10196981 0.67 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr5_-_140027175 0.67 ENST00000512088.1
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr19_+_45542773 0.65 ENST00000544944.2
CLASRP
CLK4-associating serine/arginine rich protein
chr7_-_150777920 0.65 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr7_-_150777949 0.64 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr16_+_777739 0.63 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr16_+_777246 0.63 ENST00000561546.1
ENST00000564545.1
ENST00000389703.3
ENST00000567414.1
ENST00000568141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr16_-_3422283 0.63 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr19_+_49999631 0.63 ENST00000270625.2
ENST00000596873.1
ENST00000594493.1
ENST00000599561.1
RPS11
ribosomal protein S11
chr12_+_123942188 0.62 ENST00000526639.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr11_-_17555421 0.62 ENST00000526181.1
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr6_-_31697977 0.61 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr16_+_30759700 0.60 ENST00000328273.7
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr10_-_71892555 0.60 ENST00000307864.1
AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr7_+_99202003 0.59 ENST00000609449.1
GS1-259H13.2
GS1-259H13.2
chr16_+_776936 0.59 ENST00000549114.1
ENST00000341413.4
ENST00000562187.1
ENST00000564537.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr16_+_30759563 0.59 ENST00000563588.1
ENST00000565924.1
ENST00000424889.3
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr7_-_75401513 0.56 ENST00000005180.4
CCL26
chemokine (C-C motif) ligand 26
chr17_+_48712138 0.56 ENST00000515707.1
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr19_-_9006766 0.55 ENST00000599436.1
MUC16
mucin 16, cell surface associated
chr19_-_9003586 0.54 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr14_+_103573853 0.54 ENST00000560304.1
EXOC3L4
exocyst complex component 3-like 4
chr16_-_420514 0.54 ENST00000199706.8
MRPL28
mitochondrial ribosomal protein L28
chr6_+_5085572 0.53 ENST00000405617.2
PPP1R3G
protein phosphatase 1, regulatory subunit 3G
chr8_+_35649365 0.53 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr17_+_7452189 0.52 ENST00000293825.6
TNFSF12
tumor necrosis factor (ligand) superfamily, member 12
chr6_+_31620191 0.52 ENST00000375918.2
ENST00000375920.4
APOM
apolipoprotein M
chr6_-_43027105 0.52 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
MRPL2
mitochondrial ribosomal protein L2
chr17_-_56494713 0.52 ENST00000407977.2
RNF43
ring finger protein 43
chr17_+_46970134 0.51 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr15_+_41057818 0.51 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr20_+_57264187 0.51 ENST00000525967.1
ENST00000525817.1
NPEPL1
aminopeptidase-like 1
chr7_+_102004322 0.51 ENST00000496391.1
PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr12_-_7261772 0.50 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr22_-_21984282 0.50 ENST00000398873.3
ENST00000292778.6
YDJC
YdjC homolog (bacterial)
chr3_+_37427760 0.50 ENST00000425932.1
C3orf35
chromosome 3 open reading frame 35
chr21_+_33671160 0.50 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chrY_-_21906623 0.49 ENST00000382806.2
KDM5D
lysine (K)-specific demethylase 5D
chr1_-_153517473 0.48 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr9_-_38069208 0.48 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr19_-_8373173 0.48 ENST00000537716.2
ENST00000301458.5
CD320
CD320 molecule
chr15_+_76629064 0.48 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr1_+_225997791 0.48 ENST00000445856.1
ENST00000272167.5
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr17_-_8198636 0.47 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr15_+_42131011 0.47 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr11_+_63742050 0.46 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr19_+_11670245 0.46 ENST00000585493.1
ZNF627
zinc finger protein 627
chr16_+_30212378 0.45 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr19_+_49956426 0.45 ENST00000293350.4
ENST00000540132.1
ENST00000455361.2
ENST00000433981.2
ALDH16A1
aldehyde dehydrogenase 16 family, member A1
chr1_-_159825137 0.45 ENST00000368102.1
C1orf204
chromosome 1 open reading frame 204
chr17_+_77030267 0.44 ENST00000581774.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_+_118754475 0.44 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr16_+_777118 0.44 ENST00000562141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr16_+_31366536 0.44 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr17_-_29624343 0.44 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr8_-_27472198 0.44 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU
clusterin
chr19_+_49990811 0.43 ENST00000391857.4
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr6_+_31638156 0.43 ENST00000409525.1
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr5_-_180668605 0.43 ENST00000504128.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_+_212738676 0.42 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr16_+_31366455 0.42 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr4_+_667307 0.42 ENST00000506838.1
MYL5
myosin, light chain 5, regulatory
chr8_+_67104323 0.42 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
LINC00967
long intergenic non-protein coding RNA 967
chr17_-_7531121 0.42 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr3_-_129279894 0.41 ENST00000506979.1
PLXND1
plexin D1
chr17_+_57784826 0.40 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr8_-_38126675 0.40 ENST00000531823.1
ENST00000534339.1
ENST00000524616.1
ENST00000422581.2
ENST00000424479.2
ENST00000419686.2
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr10_+_695888 0.40 ENST00000441152.2
PRR26
proline rich 26
chr8_-_17555164 0.40 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr2_+_219283815 0.40 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
VIL1
villin 1
chr5_-_45696253 0.39 ENST00000303230.4
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr9_-_140115775 0.38 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr3_+_39851094 0.38 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr11_-_45940343 0.38 ENST00000532681.1
PEX16
peroxisomal biogenesis factor 16
chr16_-_18801582 0.38 ENST00000565420.1
RPS15A
ribosomal protein S15a
chr1_-_226111929 0.37 ENST00000343818.6
ENST00000432920.2
PYCR2
RP4-559A3.7
pyrroline-5-carboxylate reductase family, member 2
Uncharacterized protein
chr4_+_668348 0.37 ENST00000511290.1
MYL5
myosin, light chain 5, regulatory
chr1_+_1260147 0.37 ENST00000343938.4
GLTPD1
glycolipid transfer protein domain containing 1
chr18_-_658244 0.37 ENST00000585033.1
ENST00000323813.3
C18orf56
chromosome 18 open reading frame 56
chr19_-_16008880 0.36 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr19_+_1248547 0.36 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chr2_+_175352114 0.36 ENST00000444196.1
ENST00000417038.1
ENST00000606406.1
AC010894.3
AC010894.3
chr7_+_72349920 0.36 ENST00000395270.1
ENST00000446813.1
ENST00000257622.4
POM121
POM121 transmembrane nucleoporin
chr22_+_30163340 0.36 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr10_+_124030819 0.36 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr17_-_2614927 0.36 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr17_+_46970127 0.35 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr16_+_22501658 0.35 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr7_-_100844193 0.35 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
MOGAT3
monoacylglycerol O-acyltransferase 3
chr16_-_18801643 0.35 ENST00000322989.4
ENST00000563390.1
RPS15A
ribosomal protein S15a
chr2_-_231084820 0.35 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr3_+_39851170 0.34 ENST00000425621.1
ENST00000396217.3
MYRIP
myosin VIIA and Rab interacting protein
chr12_+_50017184 0.34 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chrX_+_1734051 0.34 ENST00000381229.4
ENST00000381233.3
ASMT
acetylserotonin O-methyltransferase
chr19_-_51289374 0.34 ENST00000563228.1
CTD-2568A17.1
CTD-2568A17.1
chr19_-_344786 0.34 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr6_+_31637944 0.34 ENST00000375864.4
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr20_+_33462888 0.33 ENST00000336325.4
ACSS2
acyl-CoA synthetase short-chain family member 2
chr8_-_59412717 0.33 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr8_+_145203548 0.33 ENST00000534366.1
MROH1
maestro heat-like repeat family member 1
chr10_-_70092671 0.33 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr1_+_6684918 0.32 ENST00000054650.4
THAP3
THAP domain containing, apoptosis associated protein 3
chr11_+_65407331 0.32 ENST00000527525.1
SIPA1
signal-induced proliferation-associated 1
chr7_-_141957847 0.32 ENST00000552471.1
ENST00000547058.2
PRSS58
protease, serine, 58
chr17_+_46970178 0.32 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr7_-_99332719 0.32 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr12_+_10366016 0.32 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_-_7293942 0.31 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr1_-_161102421 0.31 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
DEDD
death effector domain containing
chr16_+_31128978 0.31 ENST00000448516.2
ENST00000219797.4
KAT8
K(lysine) acetyltransferase 8
chr8_+_144640499 0.31 ENST00000525721.1
ENST00000534018.1
GSDMD
gasdermin D
chr8_-_97247759 0.31 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr16_-_69448 0.31 ENST00000326592.9
WASH4P
WAS protein family homolog 4 pseudogene
chr20_-_30310336 0.30 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr10_+_106014468 0.30 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
GSTO1
glutathione S-transferase omega 1
chrX_-_46187069 0.30 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr17_-_37308824 0.30 ENST00000415163.1
ENST00000441877.1
ENST00000444911.2
PLXDC1
plexin domain containing 1
chr19_-_22193731 0.30 ENST00000601773.1
ENST00000397126.4
ENST00000601993.1
ENST00000599916.1
ZNF208
zinc finger protein 208
chr10_+_114135004 0.29 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr5_-_138725594 0.29 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr2_-_211090162 0.29 ENST00000233710.3
ACADL
acyl-CoA dehydrogenase, long chain
chr4_-_159956333 0.29 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr16_-_420338 0.29 ENST00000450882.1
ENST00000441883.1
ENST00000447696.1
ENST00000389675.2
MRPL28
mitochondrial ribosomal protein L28
chr22_-_24181174 0.29 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr17_+_73089382 0.28 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr9_+_33795533 0.28 ENST00000379405.3
PRSS3
protease, serine, 3
chr9_-_14313893 0.28 ENST00000380921.3
ENST00000380959.3
NFIB
nuclear factor I/B
chr7_-_43769051 0.28 ENST00000395880.3
COA1
cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
chr7_-_137531606 0.27 ENST00000288490.5
DGKI
diacylglycerol kinase, iota
chr7_+_43803790 0.27 ENST00000424330.1
BLVRA
biliverdin reductase A
chr1_+_205473720 0.27 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr14_-_58893832 0.27 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr6_-_160166218 0.27 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr17_-_46682321 0.27 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr2_+_234296792 0.27 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr16_+_718147 0.27 ENST00000561929.1
RHOT2
ras homolog family member T2
chr9_+_74764340 0.27 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr17_-_79838860 0.27 ENST00000582866.1
RP11-498C9.15
RP11-498C9.15
chr11_-_133826852 0.27 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr6_+_43028182 0.26 ENST00000394058.1
KLC4
kinesin light chain 4
chr9_-_130679257 0.26 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr17_-_45056606 0.26 ENST00000322329.3
RPRML
reprimo-like
chr15_+_75182346 0.26 ENST00000569931.1
ENST00000352410.4
ENST00000566377.1
ENST00000569233.1
ENST00000567132.1
ENST00000564633.1
ENST00000568907.1
ENST00000563422.1
ENST00000564003.1
ENST00000562800.1
ENST00000563786.1
ENST00000535694.1
ENST00000323744.6
ENST00000568828.1
ENST00000562606.1
ENST00000565576.1
ENST00000567570.1
MPI
mannose phosphate isomerase
chr3_+_171561127 0.26 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr11_-_18270182 0.25 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr10_+_89419370 0.25 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr8_+_119294456 0.25 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr9_-_14314066 0.25 ENST00000397575.3
NFIB
nuclear factor I/B
chr1_+_197886461 0.25 ENST00000367388.3
ENST00000337020.2
ENST00000367387.4
LHX9
LIM homeobox 9
chrX_+_1733876 0.25 ENST00000381241.3
ASMT
acetylserotonin O-methyltransferase
chr11_+_66188475 0.25 ENST00000311034.2
NPAS4
neuronal PAS domain protein 4
chr19_-_49956728 0.24 ENST00000601825.1
ENST00000596049.1
ENST00000599366.1
ENST00000597415.1
PIH1D1
PIH1 domain containing 1
chr2_-_121223697 0.24 ENST00000593290.1
FLJ14816
long intergenic non-protein coding RNA 1101
chr3_+_51976338 0.24 ENST00000417220.2
ENST00000431474.1
ENST00000398755.3
PARP3
poly (ADP-ribose) polymerase family, member 3
chr11_-_111957451 0.24 ENST00000504148.2
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr4_+_57253672 0.24 ENST00000602927.1
RP11-646I6.5
RP11-646I6.5
chr19_-_6737241 0.24 ENST00000430424.4
ENST00000597298.1
GPR108
G protein-coupled receptor 108
chr19_-_11669960 0.24 ENST00000589171.1
ENST00000590700.1
ENST00000586683.1
ENST00000593077.1
ENST00000252445.3
ELOF1
elongation factor 1 homolog (S. cerevisiae)
chr12_-_107168696 0.24 ENST00000551505.1
RP11-144F15.1
Uncharacterized protein
chr6_-_31620455 0.24 ENST00000437771.1
ENST00000404765.2
ENST00000375964.6
ENST00000211379.5
BAG6
BCL2-associated athanogene 6
chr6_+_25652432 0.24 ENST00000377961.2
SCGN
secretagogin, EF-hand calcium binding protein
chrX_+_102840408 0.24 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr2_+_220462560 0.23 ENST00000456909.1
ENST00000295641.10
STK11IP
serine/threonine kinase 11 interacting protein
chr18_-_10701979 0.23 ENST00000538948.1
ENST00000285141.4
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr2_-_25564750 0.23 ENST00000321117.5
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_-_64512273 0.23 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr7_+_23719749 0.22 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr18_+_29171689 0.22 ENST00000237014.3
TTR
transthyretin
chr7_+_95171457 0.22 ENST00000601424.1
AC002451.1
Protein LOC100996577
chr2_-_176046391 0.22 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr16_+_53412368 0.22 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr8_+_42396936 0.22 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr16_+_77756399 0.22 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr19_-_59023348 0.21 ENST00000601355.1
ENST00000263093.2
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr12_+_48722763 0.21 ENST00000335017.1
H1FNT
H1 histone family, member N, testis-specific

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.3 1.0 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 1.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 0.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.2 0.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 0.6 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 0.5 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2 1.2 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.2 1.0 GO:0051673 membrane disruption in other organism(GO:0051673)
0.2 0.6 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.5 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.4 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.4 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.4 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.5 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.3 GO:0019254 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.0 GO:0015747 urate transport(GO:0015747)
0.1 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.6 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 2.0 GO:0007620 copulation(GO:0007620)
0.1 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.2 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.7 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.3 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.2 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.2 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.1 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 0.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.3 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.5 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.5 GO:0034720 T cell antigen processing and presentation(GO:0002457) histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.5 GO:0060316 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.5 GO:0003014 renal system process(GO:0003014)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.6 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.3 GO:0046959 habituation(GO:0046959)
0.0 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.6 GO:0007567 parturition(GO:0007567)
0.0 0.2 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.4 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.4 GO:0048535 lymph node development(GO:0048535)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 1.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.0 GO:0035573 N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.3 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0061055 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0 1.1 GO:0016266 O-glycan processing(GO:0016266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 1.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.0 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 0.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.6 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 2.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.5 1.4 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.3 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.5 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.2 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 0.5 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.6 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 1.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.4 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.4 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.3 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.5 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 1.0 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.4 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995) PTB domain binding(GO:0051425)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis