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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OLIG2_NEUROD1_ATOH1

Z-value: 0.79

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol Gene ID Gene Info
OLIG2
ENSG00000205927.4 oligodendrocyte transcription factor 2
NEUROD1
ENSG00000162992.3 neuronal differentiation 1
ATOH1
ENSG00000172238.3 atonal bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OLIG2hg19_v2_chr21_+_34398153_34398250-0.165.0e-01Click!
ATOH1hg19_v2_chr4_+_94750014_94750042-0.155.2e-01Click!
NEUROD1hg19_v2_chr2_-_182545603_1825456030.126.0e-01Click!

Activity profile of OLIG2_NEUROD1_ATOH1 motif

Sorted Z-values of OLIG2_NEUROD1_ATOH1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_49834299 2.28 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr8_-_49833978 2.28 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr12_+_4382917 1.71 ENST00000261254.3
CCND2
cyclin D2
chr3_-_99833333 1.69 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L
filamin A interacting protein 1-like
chr3_-_18480260 1.52 ENST00000454909.2
SATB1
SATB homeobox 1
chr12_+_113416191 1.50 ENST00000342315.4
ENST00000392583.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr11_+_57365150 1.48 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr3_-_195310802 1.41 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr3_+_118892411 1.39 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr3_+_118892362 1.33 ENST00000497685.1
ENST00000264234.3
UPK1B
uroplakin 1B
chr19_-_11450249 1.28 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr5_+_49962772 1.19 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr4_+_1795012 1.11 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
FGFR3
fibroblast growth factor receptor 3
chr6_+_30851840 1.10 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr12_+_113416340 1.09 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr1_+_6508100 1.04 ENST00000461727.1
ESPN
espin
chr11_+_44587141 1.02 ENST00000227155.4
ENST00000342935.3
ENST00000532544.1
CD82
CD82 molecule
chr2_-_163100045 1.02 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr17_+_7341586 1.01 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr19_-_4338783 1.00 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr1_-_209792111 1.00 ENST00000455193.1
LAMB3
laminin, beta 3
chr5_+_102201722 0.91 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr19_+_41222998 0.91 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr5_+_102201687 0.89 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr11_+_44587206 0.89 ENST00000525210.1
ENST00000527737.1
ENST00000524704.1
CD82
CD82 molecule
chr3_-_18480173 0.86 ENST00000414509.1
SATB1
SATB homeobox 1
chr7_-_41742697 0.85 ENST00000242208.4
INHBA
inhibin, beta A
chr13_-_20767037 0.85 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chr3_+_49840685 0.82 ENST00000333323.4
FAM212A
family with sequence similarity 212, member A
chr5_+_102201509 0.79 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr18_+_59415396 0.76 ENST00000567801.1
RP11-1096D5.1
RP11-1096D5.1
chr12_+_6309963 0.75 ENST00000382515.2
CD9
CD9 molecule
chr1_-_153363452 0.74 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr12_-_48152428 0.73 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr9_-_33447584 0.69 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr10_-_105437909 0.68 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr21_+_30502806 0.68 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr1_+_12524965 0.67 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr12_-_52845910 0.67 ENST00000252252.3
KRT6B
keratin 6B
chr17_-_56492989 0.67 ENST00000583753.1
RNF43
ring finger protein 43
chr19_+_45281118 0.66 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr12_+_113416265 0.65 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr1_-_201346761 0.63 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr15_+_75940218 0.63 ENST00000308527.5
SNX33
sorting nexin 33
chr19_-_51466681 0.63 ENST00000456750.2
KLK6
kallikrein-related peptidase 6
chr3_+_118905564 0.59 ENST00000460625.1
UPK1B
uroplakin 1B
chrX_+_9880412 0.58 ENST00000418909.2
SHROOM2
shroom family member 2
chr2_+_69001913 0.58 ENST00000409030.3
ENST00000409220.1
ARHGAP25
Rho GTPase activating protein 25
chr20_+_33292507 0.57 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr5_+_102201430 0.57 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr12_-_58145889 0.57 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr11_+_128634589 0.56 ENST00000281428.8
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_+_69201923 0.56 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr22_+_17082732 0.55 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr8_-_128231299 0.54 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr4_-_24914576 0.54 ENST00000502801.1
ENST00000428116.2
CCDC149
coiled-coil domain containing 149
chr12_-_57634475 0.53 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr4_-_24914508 0.52 ENST00000504487.1
CCDC149
coiled-coil domain containing 149
chr12_+_6309517 0.52 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr7_+_30174426 0.52 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr15_-_41694640 0.52 ENST00000558719.1
ENST00000260361.4
ENST00000560978.1
NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr14_-_75079026 0.52 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chrX_+_150151824 0.51 ENST00000455596.1
ENST00000448905.2
HMGB3
high mobility group box 3
chr12_-_15082050 0.51 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chr11_+_124933191 0.51 ENST00000532000.1
ENST00000308074.4
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr11_+_124932986 0.49 ENST00000407458.1
ENST00000298280.5
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr11_+_111789580 0.48 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr7_+_30174668 0.48 ENST00000415604.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_+_107599267 0.48 ENST00000361318.5
ENST00000370078.1
PRMT6
protein arginine methyltransferase 6
chr13_+_38923959 0.48 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr16_-_30102547 0.48 ENST00000279386.2
TBX6
T-box 6
chr12_-_48152853 0.47 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr1_+_155051305 0.47 ENST00000368408.3
EFNA3
ephrin-A3
chrX_+_150151752 0.47 ENST00000325307.7
HMGB3
high mobility group box 3
chr15_+_81489213 0.46 ENST00000559383.1
ENST00000394660.2
IL16
interleukin 16
chr11_-_59633951 0.45 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr19_+_39687596 0.45 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr9_-_35111420 0.45 ENST00000378557.1
FAM214B
family with sequence similarity 214, member B
chr16_-_79633799 0.45 ENST00000569649.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr9_+_131644398 0.44 ENST00000372599.3
LRRC8A
leucine rich repeat containing 8 family, member A
chrX_+_47444613 0.44 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr19_-_39368887 0.44 ENST00000340740.3
ENST00000591812.1
RINL
Ras and Rab interactor-like
chr11_+_124932955 0.44 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr19_+_17416609 0.43 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr12_-_48152611 0.43 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr1_-_17304771 0.43 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr22_-_21905120 0.43 ENST00000331505.5
RIMBP3C
RIMS binding protein 3C
chr17_+_74380683 0.42 ENST00000592299.1
ENST00000590959.1
ENST00000323374.4
SPHK1
sphingosine kinase 1
chr12_-_123752624 0.42 ENST00000542174.1
ENST00000535796.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr7_+_30174574 0.42 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr7_+_143078652 0.41 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr6_-_112194484 0.41 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr1_-_154941350 0.41 ENST00000444179.1
ENST00000414115.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr6_+_30852130 0.40 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr8_-_135522425 0.40 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr1_+_19967014 0.40 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr11_+_46299199 0.39 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr8_-_139926236 0.39 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr5_+_139927213 0.39 ENST00000310331.2
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chr1_+_12538594 0.39 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr9_+_131644388 0.38 ENST00000372600.4
LRRC8A
leucine rich repeat containing 8 family, member A
chr13_+_102104952 0.38 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr11_+_118401899 0.38 ENST00000528373.1
ENST00000544878.1
ENST00000354284.4
ENST00000533137.1
ENST00000532762.1
ENST00000526973.1
ENST00000354064.7
ENST00000533102.1
ENST00000313236.5
ENST00000527267.1
ENST00000524725.1
ENST00000533689.1
TMEM25
transmembrane protein 25
chr9_+_131644781 0.37 ENST00000259324.5
LRRC8A
leucine rich repeat containing 8 family, member A
chr8_-_112248400 0.37 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chr16_+_71660079 0.36 ENST00000565261.1
ENST00000268485.3
ENST00000299952.4
MARVELD3
MARVEL domain containing 3
chr14_-_24806588 0.36 ENST00000555591.1
ENST00000554569.1
RP11-934B9.3
RIPK3
Uncharacterized protein
receptor-interacting serine-threonine kinase 3
chr5_+_3596168 0.36 ENST00000302006.3
IRX1
iroquois homeobox 1
chr16_+_4606347 0.36 ENST00000444310.4
C16orf96
chromosome 16 open reading frame 96
chr17_+_77681075 0.36 ENST00000397549.2
CTD-2116F7.1
CTD-2116F7.1
chr12_+_56473628 0.36 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr11_-_2170786 0.35 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_+_135937365 0.35 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr6_+_53948328 0.35 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr6_+_30852738 0.34 ENST00000508312.1
ENST00000512336.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr1_-_33647267 0.34 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr3_+_189349162 0.34 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr7_+_143079000 0.34 ENST00000392910.2
ZYX
zyxin
chr1_+_92632542 0.34 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr3_+_182511266 0.33 ENST00000323116.5
ENST00000493826.1
ATP11B
ATPase, class VI, type 11B
chr6_-_66417107 0.33 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr1_+_14075903 0.33 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr6_-_56716686 0.33 ENST00000520645.1
DST
dystonin
chr6_+_150464155 0.33 ENST00000361131.4
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr1_-_63782888 0.32 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr10_-_62149433 0.32 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr18_+_43753500 0.32 ENST00000587591.1
ENST00000588730.1
C18orf25
chromosome 18 open reading frame 25
chr6_+_53948221 0.32 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr12_+_57916466 0.31 ENST00000355673.3
MBD6
methyl-CpG binding domain protein 6
chr18_+_43914159 0.31 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr1_+_14075865 0.31 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr17_+_74381343 0.31 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr2_+_137523086 0.31 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr18_+_47088401 0.31 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr8_+_39972170 0.30 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr3_+_111717511 0.30 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr4_-_108204904 0.30 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr1_-_207206092 0.29 ENST00000359470.5
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr21_+_30503282 0.29 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr13_+_102104980 0.29 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr20_+_58179582 0.29 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr9_+_19408999 0.29 ENST00000340967.2
ACER2
alkaline ceramidase 2
chr10_-_64576105 0.28 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr10_-_98031265 0.28 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr17_+_38333263 0.28 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr4_+_7045042 0.28 ENST00000310074.7
ENST00000512388.1
TADA2B
transcriptional adaptor 2B
chr14_+_24641820 0.28 ENST00000560501.1
REC8
REC8 meiotic recombination protein
chrX_-_32173579 0.28 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chrX_-_102565932 0.28 ENST00000372674.1
ENST00000372677.3
BEX2
brain expressed X-linked 2
chr16_-_69385681 0.28 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr12_-_109027643 0.27 ENST00000388962.3
ENST00000550948.1
SELPLG
selectin P ligand
chr17_+_7255208 0.27 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr5_+_66124590 0.27 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr19_-_47164386 0.27 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr7_+_18535346 0.27 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chrX_-_131623043 0.27 ENST00000421707.1
MBNL3
muscleblind-like splicing regulator 3
chr19_-_6720686 0.26 ENST00000245907.6
C3
complement component 3
chr6_+_30848557 0.26 ENST00000460944.2
ENST00000324771.8
DDR1
discoidin domain receptor tyrosine kinase 1
chr15_+_44084503 0.26 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr11_+_118826999 0.26 ENST00000264031.2
UPK2
uroplakin 2
chr2_-_7005785 0.26 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr14_+_62331592 0.26 ENST00000554436.1
CTD-2277K2.1
CTD-2277K2.1
chr5_+_148521381 0.26 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chrX_+_9880590 0.25 ENST00000452575.1
SHROOM2
shroom family member 2
chr1_-_205391178 0.25 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr4_-_41216492 0.25 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr19_-_41934635 0.24 ENST00000321702.2
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr9_+_131174024 0.24 ENST00000420034.1
ENST00000372842.1
CERCAM
cerebral endothelial cell adhesion molecule
chr1_-_40367668 0.24 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr12_+_46777450 0.24 ENST00000551503.1
RP11-96H19.1
RP11-96H19.1
chr3_-_178789220 0.24 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr13_-_33780133 0.23 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr10_-_98031310 0.23 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr4_+_2814011 0.23 ENST00000502260.1
ENST00000435136.2
SH3BP2
SH3-domain binding protein 2
chr1_+_180165672 0.23 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr11_+_64948665 0.23 ENST00000533820.1
CAPN1
calpain 1, (mu/I) large subunit
chr2_+_7005959 0.23 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr19_-_19051103 0.22 ENST00000542541.2
ENST00000433218.2
HOMER3
homer homolog 3 (Drosophila)
chr1_+_104293028 0.22 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr17_+_76165213 0.22 ENST00000590201.1
SYNGR2
synaptogyrin 2
chr9_+_92219919 0.22 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr3_+_72201910 0.22 ENST00000469178.1
ENST00000485404.1
LINC00870
long intergenic non-protein coding RNA 870
chr6_-_26250835 0.22 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr11_+_117103441 0.22 ENST00000531287.1
ENST00000531452.1
RNF214
ring finger protein 214
chr14_+_24584508 0.22 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11
DDB1 and CUL4 associated factor 11
chr10_+_75668916 0.22 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr2_-_152590946 0.22 ENST00000172853.10
NEB
nebulin
chr4_+_2813946 0.22 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr7_+_18535321 0.22 ENST00000413380.1
ENST00000430454.1
HDAC9
histone deacetylase 9
chr1_+_17559776 0.21 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr20_-_31124186 0.21 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr2_+_69002052 0.21 ENST00000497079.1
ARHGAP25
Rho GTPase activating protein 25
chr19_+_50084561 0.21 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr19_-_49944806 0.21 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr9_-_128003606 0.21 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr3_-_69370095 0.21 ENST00000473029.1
FRMD4B
FERM domain containing 4B
chr3_+_183948161 0.21 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chr21_+_37692481 0.21 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3
chr22_-_36877371 0.20 ENST00000403313.1
TXN2
thioredoxin 2
chr19_-_36499521 0.20 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
SYNE4
spectrin repeat containing, nuclear envelope family member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 3.2 GO:0018032 protein amidation(GO:0018032)
0.4 1.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 1.0 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.3 1.6 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.3 3.2 GO:0018377 protein myristoylation(GO:0018377)
0.3 0.8 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 0.8 GO:0008057 eye pigment granule organization(GO:0008057)
0.3 1.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 0.7 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 2.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.6 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 0.8 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.2 0.5 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 1.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.7 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0035697 CD8-positive, alpha-beta T cell extravasation(GO:0035697) CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of T cell extravasation(GO:2000407) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 1.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.7 GO:0070295 renal water absorption(GO:0070295)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 2.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.3 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.5 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.3 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.4 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.1 0.6 GO:0036089 cleavage furrow formation(GO:0036089)
0.1 0.3 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.3 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.1 1.7 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.4 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.2 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.2 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 1.0 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.5 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:1900108 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.2 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.1 0.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.1 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.1 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.2 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.3 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.7 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 1.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.3 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.4 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.7 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.0 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.1 GO:0060844 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.5 GO:0060384 innervation(GO:0060384)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 1.0 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.0 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 1.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.0 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 1.3 GO:0042588 zymogen granule(GO:0042588)
0.1 0.9 GO:0097449 astrocyte projection(GO:0097449)
0.1 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 1.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 2.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 1.6 GO:0005902 microvillus(GO:0005902)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.3 3.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 2.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.6 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.4 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.7 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 0.2 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 4.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.0 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 1.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 4.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 3.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase