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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ONECUT1

Z-value: 0.69

Motif logo

Transcription factors associated with ONECUT1

Gene Symbol Gene ID Gene Info
ENSG00000169856.7 one cut homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ONECUT1hg19_v2_chr15_-_53082178_530822090.155.3e-01Click!

Activity profile of ONECUT1 motif

Sorted Z-values of ONECUT1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_26697304 2.58 ENST00000536498.1
vitronectin
chr12_+_21679220 2.17 ENST00000256969.2
chromosome 12 open reading frame 39
chr15_-_88799661 1.93 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr14_-_27066636 1.90 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
neuro-oncological ventral antigen 1
chr9_-_75653627 1.50 ENST00000446946.1
aldehyde dehydrogenase 1 family, member A1
chr1_-_238108575 1.38 ENST00000604646.1
MT-RNR2-like 11 (pseudogene)
chr14_-_27066960 1.38 ENST00000539517.2
neuro-oncological ventral antigen 1
chr1_-_186649543 1.37 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr9_-_116840728 1.32 ENST00000265132.3
alpha-1-microglobulin/bikunin precursor
chr10_+_28966271 1.29 ENST00000375533.3
BMP and activin membrane-bound inhibitor
chr2_+_71127699 1.29 ENST00000234392.2
ventral anterior homeobox 2
chr17_-_64225508 1.28 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr10_+_70980051 1.20 ENST00000354624.5
ENST00000395086.2
hexokinase domain containing 1
chr20_-_22566089 1.15 ENST00000377115.4
forkhead box A2
chr3_+_32280159 1.08 ENST00000458535.2
ENST00000307526.3
CKLF-like MARVEL transmembrane domain containing 8
chrX_-_151143140 1.05 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr19_-_58864848 1.04 ENST00000263100.3
alpha-1-B glycoprotein
chr1_+_26496362 1.03 ENST00000374266.5
ENST00000270812.5
zinc finger protein 593
chr5_-_176836577 1.03 ENST00000253496.3
coagulation factor XII (Hageman factor)
chrX_+_70435044 0.97 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
gap junction protein, beta 1, 32kDa
chr1_+_212738676 0.92 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr8_-_27468842 0.92 ENST00000523500.1
clusterin
chr10_+_115312766 0.71 ENST00000351270.3
hyaluronan binding protein 2
chr7_-_121944491 0.69 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr12_-_53297432 0.67 ENST00000546900.1
keratin 8
chr13_-_46679144 0.66 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr19_+_49588690 0.66 ENST00000221448.5
small nuclear ribonucleoprotein 70kDa (U1)
chrX_+_49126294 0.64 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
protein phosphatase 1, regulatory subunit 3F
chr17_-_17485731 0.62 ENST00000395783.1
phosphatidylethanolamine N-methyltransferase
chr11_+_102188272 0.62 ENST00000532808.1
baculoviral IAP repeat containing 3
chr10_-_94003003 0.61 ENST00000412050.4
cytoplasmic polyadenylation element binding protein 3
chr12_+_69742121 0.61 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
lysozyme
chr8_-_27468717 0.60 ENST00000520796.1
ENST00000520491.1
clusterin
chr12_+_70574088 0.60 ENST00000552324.1
RP11-320P7.2
chr19_+_49588677 0.59 ENST00000598984.1
ENST00000598441.1
small nuclear ribonucleoprotein 70kDa (U1)
chr7_-_32529973 0.59 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_+_127898312 0.57 ENST00000329722.7
chromosome 6 open reading frame 58
chr1_+_207262881 0.56 ENST00000451804.2
complement component 4 binding protein, beta
chr11_+_62623544 0.55 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr8_-_23712312 0.51 ENST00000290271.2
stanniocalcin 1
chr12_+_70760056 0.51 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr2_-_86850949 0.50 ENST00000237455.4
ring finger protein 103
chr4_+_110834033 0.50 ENST00000509793.1
ENST00000265171.5
epidermal growth factor
chr3_+_181429704 0.49 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr17_-_8263538 0.47 ENST00000535173.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr21_+_42792442 0.47 ENST00000398600.2
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr11_+_62623621 0.46 ENST00000535296.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr15_-_47426320 0.46 ENST00000557832.1
FKSG62
chr16_-_29499154 0.46 ENST00000354563.5
Uncharacterized protein
chr5_-_22853429 0.46 ENST00000504376.2
cadherin 12, type 2 (N-cadherin 2)
chr3_+_98699880 0.45 ENST00000473756.1
long intergenic non-protein coding RNA 973
chr20_-_22559211 0.45 ENST00000564492.1
long intergenic non-protein coding RNA 261
chr7_+_101459263 0.44 ENST00000292538.4
ENST00000393824.3
ENST00000547394.2
ENST00000360264.3
ENST00000425244.2
cut-like homeobox 1
chr9_-_77703115 0.44 ENST00000361092.4
ENST00000376808.4
nicotinamide riboside kinase 1
chr1_+_156589051 0.43 ENST00000255039.1
hyaluronan and proteoglycan link protein 2
chr17_-_56082455 0.43 ENST00000578794.1
Uncharacterized protein
chr16_+_27214802 0.43 ENST00000380948.2
ENST00000286096.4
lysine (K)-specific demethylase 8
chr19_+_45596218 0.42 ENST00000421905.1
ENST00000221462.4
protein phosphatase 1, regulatory subunit 37
chr4_-_141348999 0.42 ENST00000325617.5
calmegin
chr8_-_101719159 0.42 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr9_+_130830451 0.42 ENST00000373068.2
ENST00000373069.5
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr21_+_17961006 0.42 ENST00000602323.1
long intergenic non-protein coding RNA 478
chr14_-_35873856 0.41 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr13_-_114018400 0.41 ENST00000375430.4
ENST00000375431.4
growth hormone regulated TBC protein 1
chr20_+_36373032 0.40 ENST00000373473.1
catenin, beta like 1
chr8_+_120885949 0.40 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr1_-_63782888 0.40 ENST00000436475.2
long intergenic non-protein coding RNA 466
chr4_-_83483395 0.40 ENST00000515780.2
transmembrane protein 150C
chr3_+_32859510 0.40 ENST00000383763.5
tripartite motif containing 71, E3 ubiquitin protein ligase
chr2_-_200715834 0.40 ENST00000420128.1
ENST00000416668.1
formiminotransferase cyclodeaminase N-terminal like
chr18_+_68002675 0.39 ENST00000584919.1
Uncharacterized protein
chr4_-_130692631 0.39 ENST00000500092.2
ENST00000509105.1
RP11-519M16.1
chr11_+_47279155 0.39 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
nuclear receptor subfamily 1, group H, member 3
chr19_+_5681011 0.39 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr4_-_111563076 0.39 ENST00000354925.2
ENST00000511990.1
paired-like homeodomain 2
chr3_-_191000172 0.38 ENST00000427544.2
urotensin 2B
chr3_-_160117035 0.38 ENST00000489004.1
ENST00000496589.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr12_+_56624436 0.38 ENST00000266980.4
ENST00000437277.1
solute carrier family 39 (zinc transporter), member 5
chr1_-_26633067 0.38 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBX domain protein 11
chr17_+_79369249 0.38 ENST00000574717.2
Uncharacterized protein
chr4_-_111563279 0.37 ENST00000511837.1
paired-like homeodomain 2
chr12_+_56623827 0.37 ENST00000424625.1
ENST00000419753.1
ENST00000454355.2
ENST00000417965.1
ENST00000436633.1
solute carrier family 39 (zinc transporter), member 5
chr17_+_53342311 0.37 ENST00000226067.5
hepatic leukemia factor
chr14_+_101299520 0.37 ENST00000455531.1
maternally expressed 3 (non-protein coding)
chr10_+_114133773 0.36 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr8_-_145086922 0.35 ENST00000530478.1
poly (ADP-ribose) polymerase family, member 10
chr3_+_108308513 0.35 ENST00000361582.3
DAZ interacting zinc finger protein 3
chr1_+_156589198 0.35 ENST00000456112.1
hyaluronan and proteoglycan link protein 2
chr15_-_64338521 0.34 ENST00000457488.1
ENST00000558069.1
death-associated protein kinase 2
chr10_+_115312825 0.34 ENST00000537906.1
ENST00000541666.1
hyaluronan binding protein 2
chr16_+_31044413 0.34 ENST00000394998.1
syntaxin 4
chr22_+_24198890 0.34 ENST00000345044.6
solute carrier family 2 (facilitated glucose transporter), member 11
chr19_-_19729725 0.33 ENST00000251203.9
pre-B-cell leukemia homeobox 4
chr8_-_101718991 0.32 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr22_-_37505588 0.31 ENST00000406856.1
transmembrane protease, serine 6
chr5_+_32585605 0.31 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1 homolog (S. cerevisiae)
chr22_-_37505449 0.31 ENST00000406725.1
transmembrane protease, serine 6
chr12_-_21487829 0.30 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
solute carrier organic anion transporter family, member 1A2
chr10_+_105881779 0.30 ENST00000369729.3
SWI5-dependent recombination repair 1
chr9_-_77703056 0.30 ENST00000376811.1
nicotinamide riboside kinase 1
chr2_-_197457335 0.30 ENST00000260983.3
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr11_+_85359002 0.30 ENST00000528105.1
ENST00000304511.2
transmembrane protein 126A
chr17_-_79876010 0.30 ENST00000328666.6
sirtuin 7
chr8_-_121457608 0.29 ENST00000306185.3
mitochondrial ribosomal protein L13
chr12_-_56359802 0.29 ENST00000548803.1
ENST00000449260.2
ENST00000550447.1
ENST00000547137.1
ENST00000546543.1
ENST00000550464.1
premelanosome protein
chr11_-_118305921 0.29 ENST00000532619.1
RP11-770J1.4
chr4_-_175443484 0.28 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr2_-_161350305 0.28 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr10_-_127505167 0.28 ENST00000368786.1
uroporphyrinogen III synthase
chr16_-_75467318 0.28 ENST00000283882.3
craniofacial development protein 1
chr6_+_2246023 0.27 ENST00000530833.1
ENST00000525811.1
ENST00000534441.1
ENST00000533653.1
ENST00000534468.1
GMDS antisense RNA 1 (head to head)
chr12_+_15475462 0.27 ENST00000543886.1
ENST00000348962.2
protein tyrosine phosphatase, receptor type, O
chr10_+_105881906 0.27 ENST00000369727.3
ENST00000336358.5
SWI5-dependent recombination repair 1
chr5_-_151784838 0.27 ENST00000255262.3
neuromedin U receptor 2
chrX_+_122318006 0.26 ENST00000371266.1
ENST00000264357.5
glutamate receptor, ionotropic, AMPA 3
chr5_-_156362666 0.26 ENST00000406964.1
T-cell immunoglobulin and mucin domain containing 4
chr11_-_105948129 0.26 ENST00000526793.1
kelch repeat and BTB (POZ) domain containing 3
chr3_-_52273098 0.26 ENST00000499914.2
ENST00000305533.5
ENST00000597542.1
twinfilin actin-binding protein 2
toll-like receptor 9
chr4_-_168155169 0.26 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr15_-_86338134 0.25 ENST00000337975.5
kelch-like family member 25
chr1_+_156756667 0.25 ENST00000526188.1
ENST00000454659.1
papillary renal cell carcinoma (translocation-associated)
chr1_-_26633480 0.25 ENST00000450041.1
UBX domain protein 11
chr13_+_30002846 0.25 ENST00000542829.1
microtubule associated tumor suppressor candidate 2
chr5_-_20575959 0.25 ENST00000507958.1
cadherin 18, type 2
chr6_+_27925019 0.25 ENST00000244623.1
olfactory receptor, family 2, subfamily B, member 6
chr10_-_46167722 0.25 ENST00000374366.3
ENST00000344646.5
zinc finger, AN1-type domain 4
chr4_-_103940791 0.24 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chrX_-_16887963 0.24 ENST00000380084.4
retinoblastoma binding protein 7
chr17_-_26220366 0.24 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYR motif containing 9
Uncharacterized protein
chr15_+_48051920 0.24 ENST00000559196.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr14_+_38264418 0.24 ENST00000267368.7
ENST00000382320.3
tetratricopeptide repeat domain 6
chr1_-_177939348 0.24 ENST00000464631.2
SEC16 homolog B (S. cerevisiae)
chr7_-_132261253 0.24 ENST00000321063.4
plexin A4
chr10_-_5227096 0.24 ENST00000488756.1
ENST00000334314.3
aldo-keto reductase family 1, member C-like 1
chr3_+_159557637 0.23 ENST00000445224.2
schwannomin interacting protein 1
chr7_-_5998714 0.23 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr16_-_75467274 0.23 ENST00000566254.1
craniofacial development protein 1
chr13_+_30002741 0.23 ENST00000380808.2
microtubule associated tumor suppressor candidate 2
chr1_-_197036364 0.22 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr19_-_5680891 0.22 ENST00000309324.4
chromosome 19 open reading frame 70
chr3_+_148415571 0.22 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
angiotensin II receptor, type 1
chr10_-_4285923 0.22 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr7_-_78400598 0.22 ENST00000536571.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_59726565 0.22 ENST00000412930.2
FKSG52
chr14_-_74892805 0.22 ENST00000331628.3
ENST00000554953.1
synapse differentiation inducing 1-like
chr10_+_63661053 0.22 ENST00000279873.7
AT rich interactive domain 5B (MRF1-like)
chr6_-_31651817 0.21 ENST00000375863.3
ENST00000375860.2
lymphocyte antigen 6 complex, locus G5C
chr19_+_33865218 0.21 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr19_-_50168861 0.21 ENST00000596756.1
interferon regulatory factor 3
chr5_+_167956121 0.21 ENST00000338333.4
fibrillarin-like 1
chr15_-_74421477 0.21 ENST00000514871.1
HCG2004779; Uncharacterized protein
chr21_-_43816052 0.21 ENST00000398405.1
transmembrane protease, serine 3
chr1_+_25598872 0.21 ENST00000328664.4
Rh blood group, D antigen
chrX_+_14547632 0.21 ENST00000218075.4
glycine receptor, alpha 2
chr1_+_152178320 0.21 ENST00000429352.1
RP11-107M16.2
chr7_-_29235063 0.21 ENST00000437527.1
ENST00000455544.1
carboxypeptidase, vitellogenic-like
chr21_-_43816152 0.21 ENST00000433957.2
ENST00000398397.3
transmembrane protease, serine 3
chr18_-_49557 0.21 ENST00000308911.6
Tubulin beta-8 chain-like protein LOC260334
chr14_+_24407940 0.21 ENST00000354854.1
DHRS4-AS1
chr1_-_165414414 0.20 ENST00000359842.5
retinoid X receptor, gamma
chr14_+_24422795 0.20 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
dehydrogenase/reductase (SDR family) member 4
chr13_-_46679185 0.20 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr18_-_31802056 0.20 ENST00000538587.1
nucleolar protein 4
chr8_+_95558771 0.20 ENST00000391679.1
HCG2009141; PRO2397; Uncharacterized protein
chr9_-_101471479 0.20 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr16_-_69788816 0.20 ENST00000268802.5
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr2_+_234959323 0.19 ENST00000373368.1
ENST00000168148.3
secreted phosphoprotein 2, 24kDa
chr2_+_234959376 0.19 ENST00000425558.1
secreted phosphoprotein 2, 24kDa
chr15_+_69854027 0.19 ENST00000498938.2
RP11-279F6.1
chr2_-_99870744 0.19 ENST00000409238.1
ENST00000423800.1
lysozyme G-like 2
chrX_-_71792477 0.19 ENST00000421523.1
ENST00000415409.1
ENST00000373559.4
ENST00000373556.3
ENST00000373560.2
ENST00000373583.1
ENST00000429103.2
ENST00000373571.1
ENST00000373554.1
histone deacetylase 8
chr7_-_26240357 0.19 ENST00000354667.4
ENST00000356674.7
heterogeneous nuclear ribonucleoprotein A2/B1
chr18_-_31802282 0.19 ENST00000535475.1
nucleolar protein 4
chrX_+_10124977 0.19 ENST00000380833.4
chloride channel, voltage-sensitive 4
chr6_-_46048116 0.19 ENST00000185206.6
chloride intracellular channel 5
chr6_-_27799305 0.18 ENST00000357549.2
histone cluster 1, H4k
chr12_+_43086018 0.18 ENST00000550177.1
RP11-25I15.3
chr6_-_161695074 0.18 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr7_+_129007964 0.18 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
adenosylhomocysteinase-like 2
chr20_+_21686290 0.18 ENST00000398485.2
paired box 1
chr13_-_30683005 0.18 ENST00000413591.1
ENST00000432770.1
long intergenic non-protein coding RNA 365
chr9_-_138853156 0.17 ENST00000371756.3
UBA domain containing 1
chr7_-_69062391 0.17 ENST00000436600.2
RP5-942I16.1
chr14_+_62585332 0.17 ENST00000554895.1
long intergenic non-protein coding RNA 643
chr1_+_109256067 0.17 ENST00000271311.2
fibronectin type III domain containing 7
chr2_+_223536428 0.17 ENST00000446656.3
monoacylglycerol O-acyltransferase 1
chr5_+_140165876 0.16 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
protocadherin alpha 1
chr15_-_64995399 0.16 ENST00000559753.1
ENST00000560258.2
ENST00000559912.2
ENST00000326005.6
ornithine decarboxylase antizyme 2
chr18_+_74207477 0.16 ENST00000532511.1
uncharacterized protein LOC400658
chrX_+_122318113 0.16 ENST00000371264.3
glutamate receptor, ionotropic, AMPA 3
chr12_+_15475331 0.16 ENST00000281171.4
protein tyrosine phosphatase, receptor type, O
chr18_-_44775554 0.16 ENST00000425639.1
ENST00000400404.1
SKI family transcriptional corepressor 2
chr15_-_89089860 0.16 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
de-etiolated homolog 1 (Arabidopsis)
chr6_-_133055815 0.15 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
vanin 3
chr2_+_20650796 0.15 ENST00000448241.1
AC023137.2
chr7_+_141408153 0.15 ENST00000397541.2
WEE1 homolog 2 (S. pombe)
chr21_-_30445886 0.15 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
chaperonin containing TCP1, subunit 8 (theta)
chr7_-_132261223 0.15 ENST00000423507.2
plexin A4
chr17_-_50235423 0.15 ENST00000340813.6
carbonic anhydrase X
chr6_+_73076432 0.14 ENST00000414192.2
regulating synaptic membrane exocytosis 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.5 1.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 1.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.3 1.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.3 0.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 1.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 1.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.9 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 1.3 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.2 0.6 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 1.5 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.8 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.2 0.8 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 1.0 GO:0060356 leucine import(GO:0060356)
0.1 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 2.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.8 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 1.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.4 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 1.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.3 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 1.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.3 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.2 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.4 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:1901895 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.6 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.4 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.2 GO:0061056 sclerotome development(GO:0061056)
0.1 0.4 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 1.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.2 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 1.3 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.2 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.5 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.2 GO:0046498 S-adenosylmethionine cycle(GO:0033353) S-adenosylhomocysteine metabolic process(GO:0046498) S-adenosylmethionine metabolic process(GO:0046500)
0.0 0.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.6 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.1 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.6 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 1.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.5 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:1901631 positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.7 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.3 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 0.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.6 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.3 GO:0000243 commitment complex(GO:0000243)
0.1 1.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 1.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0070703 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0019862 IgA binding(GO:0019862)
0.3 1.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.3 1.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.2 1.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.6 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.2 1.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 1.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 3.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 2.5 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.0 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 2.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation