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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ONECUT2_ONECUT3

Z-value: 0.65

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Transcription factors associated with ONECUT2_ONECUT3

Gene Symbol Gene ID Gene Info
ONECUT2
ENSG00000119547.5 one cut homeobox 2
ONECUT3
ENSG00000205922.4 one cut homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ONECUT3hg19_v2_chr19_+_1752372_1752372-0.642.3e-03Click!
ONECUT2hg19_v2_chr18_+_55102917_55102985-0.596.3e-03Click!

Activity profile of ONECUT2_ONECUT3 motif

Sorted Z-values of ONECUT2_ONECUT3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_28192360 2.62 ENST00000570033.1
XPO6
exportin 6
chr7_-_30009542 2.23 ENST00000438497.1
SCRN1
secernin 1
chr2_+_157330081 1.96 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr17_+_61151306 1.85 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_-_208030295 1.49 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr7_-_30008849 1.36 ENST00000409497.1
SCRN1
secernin 1
chr15_-_83837983 1.30 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr17_+_17685422 1.29 ENST00000395774.1
RAI1
retinoic acid induced 1
chr2_+_102413726 1.25 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr12_+_4385230 1.14 ENST00000536537.1
CCND2
cyclin D2
chrX_-_119693745 1.02 ENST00000371323.2
CUL4B
cullin 4B
chr6_+_15401075 0.97 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr4_-_102267953 0.95 ENST00000523694.2
ENST00000507176.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr17_+_44701402 0.88 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr12_-_76817036 0.87 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr7_-_104909435 0.85 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr6_+_56954919 0.83 ENST00000508603.1
ENST00000491832.2
ENST00000370710.6
ZNF451
zinc finger protein 451
chr2_-_208030886 0.76 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr18_+_11752783 0.74 ENST00000585642.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chrX_-_85302531 0.73 ENST00000537751.1
ENST00000358786.4
ENST00000357749.2
CHM
choroideremia (Rab escort protein 1)
chr15_+_93443419 0.71 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr20_-_1309809 0.70 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr14_+_62164340 0.68 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr14_+_37126765 0.67 ENST00000402703.2
PAX9
paired box 9
chr7_+_133615169 0.66 ENST00000541309.1
EXOC4
exocyst complex component 4
chr11_-_107729504 0.65 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr7_-_107968999 0.63 ENST00000456431.1
NRCAM
neuronal cell adhesion molecule
chr6_+_56954808 0.61 ENST00000510483.1
ENST00000370706.4
ENST00000357489.3
ZNF451
zinc finger protein 451
chr9_-_27529726 0.61 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr8_+_133787586 0.59 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr11_-_107729287 0.58 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr4_-_102268708 0.57 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_243326612 0.56 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr18_+_11752040 0.55 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_+_99127225 0.52 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr19_-_44952635 0.51 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
ZNF229
zinc finger protein 229
chr2_-_192016276 0.51 ENST00000413064.1
STAT4
signal transducer and activator of transcription 4
chr7_-_151330218 0.51 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr9_-_127710292 0.48 ENST00000421514.1
GOLGA1
golgin A1
chr5_-_143550241 0.47 ENST00000522203.1
YIPF5
Yip1 domain family, member 5
chr11_+_134144139 0.47 ENST00000389887.5
GLB1L3
galactosidase, beta 1-like 3
chr13_+_97928395 0.44 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr4_-_102268484 0.43 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_-_139372141 0.42 ENST00000313050.7
SEC16A
SEC16 homolog A (S. cerevisiae)
chr6_+_126221034 0.42 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr11_+_8040739 0.41 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr2_-_55646412 0.41 ENST00000413716.2
CCDC88A
coiled-coil domain containing 88A
chr2_-_208030647 0.40 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_+_64846129 0.39 ENST00000540417.1
ENST00000539810.1
TBK1
TANK-binding kinase 1
chr22_-_36220420 0.38 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_69985734 0.38 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr11_-_116658758 0.38 ENST00000227322.3
ZNF259
zinc finger protein 259
chr2_+_109204743 0.38 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr11_-_116658695 0.38 ENST00000429220.1
ENST00000444935.1
ZNF259
zinc finger protein 259
chr7_-_107968921 0.38 ENST00000442580.1
NRCAM
neuronal cell adhesion molecule
chr7_-_23510086 0.37 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chrX_+_46771711 0.37 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chrX_+_100805496 0.37 ENST00000372829.3
ARMCX1
armadillo repeat containing, X-linked 1
chr3_-_11685345 0.36 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr18_-_46895066 0.35 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
DYM
dymeclin
chr2_-_192016316 0.35 ENST00000358470.4
ENST00000432798.1
ENST00000450994.1
STAT4
signal transducer and activator of transcription 4
chr4_-_103746683 0.35 ENST00000504211.1
ENST00000508476.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr11_-_10828892 0.35 ENST00000525681.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr5_-_146833222 0.35 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr4_+_169418255 0.34 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr3_-_141747439 0.34 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_146068184 0.33 ENST00000604894.1
ENST00000369323.3
ENST00000479926.2
NBPF11
neuroblastoma breakpoint family, member 11
chr4_-_103746924 0.33 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr5_-_146833485 0.33 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chrX_-_117119243 0.33 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr11_+_34643600 0.33 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr4_-_103747011 0.32 ENST00000350435.7
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr17_+_28705921 0.31 ENST00000225719.4
CPD
carboxypeptidase D
chr2_-_113012592 0.30 ENST00000272570.5
ENST00000409573.2
ZC3H8
zinc finger CCCH-type containing 8
chr5_+_162887556 0.30 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR
hyaluronan-mediated motility receptor (RHAMM)
chr1_-_26233423 0.30 ENST00000357865.2
STMN1
stathmin 1
chrX_-_64196351 0.29 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chr5_-_146833803 0.29 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr12_+_32832203 0.28 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L
dynamin 1-like
chr1_-_147610081 0.28 ENST00000369226.3
NBPF24
neuroblastoma breakpoint family, member 24
chr15_+_38746307 0.28 ENST00000397609.2
ENST00000491535.1
FAM98B
family with sequence similarity 98, member B
chr10_-_419129 0.27 ENST00000540204.1
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr3_-_93747425 0.27 ENST00000315099.2
STX19
syntaxin 19
chr11_-_107729887 0.27 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr12_-_54653313 0.26 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr11_-_117170403 0.25 ENST00000504995.1
BACE1
beta-site APP-cleaving enzyme 1
chr6_+_130339710 0.25 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chrX_-_64196376 0.25 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chr15_+_86098670 0.25 ENST00000558811.1
AKAP13
A kinase (PRKA) anchor protein 13
chr21_+_39628852 0.25 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_116383738 0.24 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr12_+_100594557 0.24 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr6_+_56954867 0.24 ENST00000370708.4
ENST00000370702.1
ZNF451
zinc finger protein 451
chr13_+_31774073 0.24 ENST00000343307.4
B3GALTL
beta 1,3-galactosyltransferase-like
chr14_+_67831576 0.23 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_-_141747459 0.23 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_-_143550159 0.22 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
YIPF5
Yip1 domain family, member 5
chrX_+_46771848 0.22 ENST00000218343.4
PHF16
jade family PHD finger 3
chr3_+_69985792 0.22 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr17_-_76824975 0.22 ENST00000586066.2
USP36
ubiquitin specific peptidase 36
chr12_+_64845864 0.22 ENST00000538890.1
TBK1
TANK-binding kinase 1
chr8_-_82645082 0.21 ENST00000523361.1
ZFAND1
zinc finger, AN1-type domain 1
chr10_-_62332357 0.20 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_+_18154059 0.20 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chrX_+_123095860 0.20 ENST00000428941.1
STAG2
stromal antigen 2
chr11_+_6947647 0.20 ENST00000278319.5
ZNF215
zinc finger protein 215
chr14_+_37131058 0.20 ENST00000361487.6
PAX9
paired box 9
chr4_+_71588372 0.20 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr9_+_70856397 0.19 ENST00000360171.6
CBWD3
COBW domain containing 3
chr18_+_29671812 0.19 ENST00000261593.3
ENST00000578914.1
RNF138
ring finger protein 138, E3 ubiquitin protein ligase
chrX_-_64196307 0.19 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr1_-_100598444 0.19 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr16_-_30621663 0.19 ENST00000287461.3
ZNF689
zinc finger protein 689
chrX_+_70586082 0.18 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr4_+_169418195 0.18 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr13_+_103459704 0.18 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr4_-_102268628 0.17 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr6_-_151773232 0.17 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr10_-_98031265 0.17 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chrX_+_123095890 0.17 ENST00000435215.1
STAG2
stromal antigen 2
chr3_+_130650738 0.17 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr19_+_37997812 0.17 ENST00000542455.1
ENST00000587143.1
ZNF793
zinc finger protein 793
chr1_+_206730484 0.17 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr10_+_114710516 0.17 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr10_-_98031310 0.17 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr10_+_69869237 0.16 ENST00000373675.3
MYPN
myopalladin
chr9_-_70490107 0.15 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr1_-_159684371 0.15 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
CRP
C-reactive protein, pentraxin-related
chr3_-_24207039 0.14 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr7_-_84121858 0.14 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_+_121774202 0.14 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr6_+_158733692 0.13 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr12_+_32832134 0.13 ENST00000452533.2
DNM1L
dynamin 1-like
chr5_-_160279207 0.13 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr3_-_71632894 0.13 ENST00000493089.1
FOXP1
forkhead box P1
chr7_-_14026063 0.12 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr3_-_155394152 0.12 ENST00000494598.1
PLCH1
phospholipase C, eta 1
chr10_-_73975657 0.12 ENST00000394919.1
ENST00000526751.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr19_-_4535233 0.12 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr5_+_147774275 0.12 ENST00000513826.1
FBXO38
F-box protein 38
chr1_+_144811744 0.12 ENST00000338347.4
ENST00000440491.2
ENST00000375552.4
NBPF9
neuroblastoma breakpoint family, member 9
chr17_+_7461613 0.11 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr5_+_136070614 0.11 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr1_+_145883868 0.10 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr1_+_114473350 0.10 ENST00000503968.1
HIPK1
homeodomain interacting protein kinase 1
chr2_-_39348137 0.09 ENST00000426016.1
SOS1
son of sevenless homolog 1 (Drosophila)
chr19_-_52674896 0.09 ENST00000322146.8
ENST00000597065.1
ZNF836
zinc finger protein 836
chr3_-_108836945 0.09 ENST00000483760.1
MORC1
MORC family CW-type zinc finger 1
chr21_+_39628780 0.09 ENST00000417042.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_207262578 0.09 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr11_-_102651343 0.08 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr3_+_10312604 0.08 ENST00000426850.1
TATDN2
TatD DNase domain containing 2
chr3_+_187461442 0.08 ENST00000450760.1
RP11-211G3.2
RP11-211G3.2
chr16_+_25228242 0.08 ENST00000219660.5
AQP8
aquaporin 8
chr12_-_122017542 0.08 ENST00000446152.2
KDM2B
lysine (K)-specific demethylase 2B
chr4_-_69434245 0.07 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr6_-_79787902 0.07 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr6_+_71122974 0.07 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr1_-_116383322 0.07 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr10_+_133753533 0.07 ENST00000422256.2
PPP2R2D
protein phosphatase 2, regulatory subunit B, delta
chr14_+_77607026 0.07 ENST00000600936.1
AC007375.1
Uncharacterized protein; cDNA FLJ43210 fis, clone FEBRA2020582
chr2_+_171034646 0.07 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr2_-_100925967 0.06 ENST00000409647.1
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr5_+_140800638 0.06 ENST00000398587.2
ENST00000518882.1
PCDHGA11
protocadherin gamma subfamily A, 11
chr7_-_14026123 0.06 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr6_+_37400974 0.06 ENST00000455891.1
ENST00000373451.4
CMTR1
cap methyltransferase 1
chr1_-_115259337 0.06 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr17_+_7461849 0.06 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_-_122018114 0.05 ENST00000539394.1
KDM2B
lysine (K)-specific demethylase 2B
chr11_-_115158193 0.05 ENST00000543540.1
CADM1
cell adhesion molecule 1
chr8_-_108510224 0.05 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr6_-_154751629 0.05 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr8_+_22601 0.05 ENST00000522481.3
ENST00000518652.1
AC144568.2
Uncharacterized protein
chr17_-_70989072 0.04 ENST00000582769.1
SLC39A11
solute carrier family 39, member 11
chr8_-_117043 0.04 ENST00000320901.3
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr20_+_58571419 0.04 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr4_-_100212132 0.04 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chrX_+_47093171 0.04 ENST00000377078.2
USP11
ubiquitin specific peptidase 11
chr12_-_122018346 0.04 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr9_+_95726243 0.04 ENST00000416701.2
FGD3
FYVE, RhoGEF and PH domain containing 3
chr17_-_39623681 0.04 ENST00000225899.3
KRT32
keratin 32
chr7_+_43152212 0.04 ENST00000453890.1
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr1_+_207262627 0.03 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr17_-_37764128 0.03 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr21_+_39628655 0.03 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_+_7461781 0.03 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_+_170440902 0.03 ENST00000448752.2
ENST00000418888.1
ENST00000414307.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr19_+_7598890 0.03 ENST00000221249.6
ENST00000601668.1
ENST00000601001.1
PNPLA6
patatin-like phospholipase domain containing 6
chr8_+_77593474 0.02 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr5_+_65440032 0.02 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr19_+_13135386 0.02 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_-_118550375 0.02 ENST00000525958.1
ENST00000264029.4
ENST00000397925.1
ENST00000529101.1
TREH
trehalase (brush-border membrane glycoprotein)
chr5_+_128300810 0.02 ENST00000262462.4
SLC27A6
solute carrier family 27 (fatty acid transporter), member 6
chr2_+_109204909 0.02 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_+_123480194 0.02 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr3_-_100565249 0.02 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr16_+_72088376 0.02 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr4_+_71587669 0.02 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr1_+_110655050 0.01 ENST00000334179.3
UBL4B
ubiquitin-like 4B
chr8_+_104831440 0.01 ENST00000515551.1
RIMS2
regulating synaptic membrane exocytosis 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT2_ONECUT3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.5 2.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.4 2.0 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.9 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.4 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.7 GO:0070101 neural fold elevation formation(GO:0021502) elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.9 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 1.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 1.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.7 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 1.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 1.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 2.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.9 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.3 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.1 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 1.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 2.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 3.6 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 2.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 1.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation