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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OSR1_OSR2

Z-value: 0.45

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Transcription factors associated with OSR1_OSR2

Gene Symbol Gene ID Gene Info
OSR1
ENSG00000143867.5 odd-skipped related transcription factor 1
OSR2
ENSG00000164920.5 odd-skipped related transciption factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OSR2hg19_v2_chr8_+_99956759_999568870.512.1e-02Click!
OSR1hg19_v2_chr2_-_19558373_195584140.436.1e-02Click!

Activity profile of OSR1_OSR2 motif

Sorted Z-values of OSR1_OSR2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_134212312 1.06 ENST00000359579.4
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr10_-_94301107 0.84 ENST00000436178.1
IDE
insulin-degrading enzyme
chr12_-_50419177 0.82 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1
Rac GTPase activating protein 1
chr9_-_95055923 0.73 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chr9_-_95055956 0.71 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr5_+_68463043 0.69 ENST00000508407.1
ENST00000505500.1
CCNB1
cyclin B1
chr5_+_169011033 0.63 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr9_-_95056010 0.59 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr8_+_66619277 0.57 ENST00000521247.2
ENST00000527155.1
MTFR1
mitochondrial fission regulator 1
chr5_+_68462944 0.57 ENST00000506572.1
CCNB1
cyclin B1
chr5_+_68462837 0.55 ENST00000256442.5
CCNB1
cyclin B1
chr17_-_46690839 0.54 ENST00000498634.2
HOXB8
homeobox B8
chr5_+_169010638 0.53 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr1_+_12042015 0.52 ENST00000412236.1
MFN2
mitofusin 2
chr3_-_186080012 0.46 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr2_-_74007095 0.44 ENST00000452812.1
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr11_-_96123022 0.43 ENST00000542662.1
CCDC82
coiled-coil domain containing 82
chr14_+_56127960 0.38 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr4_-_40516560 0.38 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr5_+_110073853 0.37 ENST00000513807.1
ENST00000509442.2
SLC25A46
solute carrier family 25, member 46
chr17_-_79895097 0.36 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr15_+_75491203 0.36 ENST00000562637.1
C15orf39
chromosome 15 open reading frame 39
chr16_+_88493879 0.36 ENST00000565624.1
ENST00000437464.1
ZNF469
zinc finger protein 469
chr16_+_23690138 0.35 ENST00000300093.4
PLK1
polo-like kinase 1
chr3_+_149191723 0.35 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr14_+_56127989 0.35 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr1_-_204463829 0.34 ENST00000429009.1
ENST00000415899.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr3_+_149192475 0.34 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr3_-_112693865 0.34 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1
CD200 receptor 1
chrX_-_134049233 0.33 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr17_-_79895154 0.33 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr2_-_44588624 0.33 ENST00000438314.1
ENST00000409936.1
PREPL
prolyl endopeptidase-like
chr2_-_44588893 0.31 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL
prolyl endopeptidase-like
chr8_+_125486939 0.30 ENST00000303545.3
RNF139
ring finger protein 139
chr5_+_135383008 0.29 ENST00000508767.1
ENST00000604555.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr2_-_37458749 0.29 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr8_+_94710789 0.29 ENST00000523475.1
FAM92A1
family with sequence similarity 92, member A1
chr7_-_6388537 0.29 ENST00000313324.4
ENST00000530143.1
FAM220A
family with sequence similarity 220, member A
chr1_+_218458625 0.28 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr9_+_36572851 0.27 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr17_-_79894651 0.27 ENST00000584848.1
ENST00000577756.1
ENST00000329875.8
PYCR1
pyrroline-5-carboxylate reductase 1
chr10_+_95848824 0.27 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr7_-_95225768 0.27 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr15_-_66649010 0.26 ENST00000367709.4
ENST00000261881.4
TIPIN
TIMELESS interacting protein
chr2_+_87754989 0.26 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr6_-_136788001 0.26 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr2_+_178257372 0.26 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr7_+_16700806 0.26 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr2_-_44588679 0.26 ENST00000409411.1
PREPL
prolyl endopeptidase-like
chr1_-_231560790 0.25 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr15_+_41523417 0.25 ENST00000560397.1
CHP1
calcineurin-like EF-hand protein 1
chr21_+_40752170 0.25 ENST00000333781.5
ENST00000541890.1
WRB
tryptophan rich basic protein
chr3_-_45957088 0.24 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr15_+_36994210 0.23 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr2_-_44588694 0.23 ENST00000409957.1
PREPL
prolyl endopeptidase-like
chr17_-_191188 0.23 ENST00000575634.1
RPH3AL
rabphilin 3A-like (without C2 domains)
chr20_+_23342783 0.23 ENST00000544236.1
ENST00000338121.5
ENST00000542987.1
ENST00000424216.1
GZF1
GDNF-inducible zinc finger protein 1
chr14_-_88459503 0.23 ENST00000393568.4
ENST00000261304.2
GALC
galactosylceramidase
chr2_-_148779106 0.22 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr17_+_61271355 0.22 ENST00000583356.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr8_+_37594185 0.22 ENST00000518586.1
ENST00000335171.6
ENST00000521644.1
ERLIN2
ER lipid raft associated 2
chr5_+_140306302 0.22 ENST00000409700.3
PCDHAC1
protocadherin alpha subfamily C, 1
chr2_+_87754887 0.21 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr7_-_6312206 0.21 ENST00000350796.3
CYTH3
cytohesin 3
chr9_-_98268883 0.21 ENST00000551630.1
ENST00000548420.1
PTCH1
patched 1
chr8_+_26247878 0.21 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr11_+_62648336 0.20 ENST00000338663.7
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr19_-_17185848 0.20 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr13_+_97874574 0.20 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr1_+_201798269 0.19 ENST00000361565.4
IPO9
importin 9
chr2_-_133104839 0.19 ENST00000608279.1
RP11-725P16.2
RP11-725P16.2
chr10_-_36812323 0.19 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr14_+_93651296 0.19 ENST00000283534.4
ENST00000557574.1
TMEM251
RP11-371E8.4
transmembrane protein 251
Uncharacterized protein
chr10_+_101088836 0.18 ENST00000356713.4
CNNM1
cyclin M1
chr9_+_103189660 0.18 ENST00000374886.3
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr19_+_39989535 0.18 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr3_+_140947563 0.18 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr19_+_39989580 0.18 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chr14_-_88459182 0.17 ENST00000544807.2
GALC
galactosylceramidase
chr2_+_217277466 0.17 ENST00000358207.5
ENST00000434435.1
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr9_+_127023704 0.16 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr2_+_37458928 0.16 ENST00000439218.1
ENST00000432075.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr3_+_101504200 0.16 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr2_-_178257401 0.15 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr7_-_105752971 0.15 ENST00000011473.2
SYPL1
synaptophysin-like 1
chr1_-_179112189 0.15 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr4_-_77996032 0.15 ENST00000505609.1
CCNI
cyclin I
chr12_+_94656297 0.15 ENST00000545312.1
PLXNC1
plexin C1
chr1_-_156722195 0.14 ENST00000368206.5
HDGF
hepatoma-derived growth factor
chr2_+_87755054 0.14 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr8_+_37594130 0.14 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2
ER lipid raft associated 2
chr20_+_31407692 0.13 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr22_-_42336209 0.13 ENST00000472374.2
CENPM
centromere protein M
chr2_+_70056762 0.13 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr5_+_140306478 0.13 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr14_+_65453432 0.13 ENST00000246166.2
FNTB
farnesyltransferase, CAAX box, beta
chr5_+_36152091 0.13 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr12_+_27396901 0.13 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr17_-_72869140 0.12 ENST00000583917.1
ENST00000293195.5
ENST00000442102.2
FDXR
ferredoxin reductase
chr8_+_37594103 0.12 ENST00000397228.2
ERLIN2
ER lipid raft associated 2
chr8_+_96037255 0.12 ENST00000286687.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chrX_-_134049262 0.12 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr3_+_50654821 0.12 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr11_-_63439381 0.12 ENST00000538786.1
ENST00000540699.1
ATL3
atlastin GTPase 3
chr19_+_19144666 0.12 ENST00000535288.1
ENST00000538663.1
ARMC6
armadillo repeat containing 6
chr17_-_72869086 0.12 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
FDXR
ferredoxin reductase
chr3_-_119182506 0.11 ENST00000468676.1
TMEM39A
transmembrane protein 39A
chr7_+_112090483 0.11 ENST00000403825.3
ENST00000429071.1
IFRD1
interferon-related developmental regulator 1
chr11_+_64808675 0.11 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr15_-_74284558 0.11 ENST00000359750.4
ENST00000541638.1
ENST00000562453.1
STOML1
stomatin (EPB72)-like 1
chr19_-_41220957 0.11 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
ADCK4
aarF domain containing kinase 4
chr5_+_135468516 0.10 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr22_+_42017280 0.10 ENST00000402580.3
ENST00000428575.2
ENST00000359308.4
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr4_-_8430152 0.10 ENST00000514423.1
ENST00000503233.1
ACOX3
acyl-CoA oxidase 3, pristanoyl
chr14_-_54955376 0.10 ENST00000553333.1
GMFB
glia maturation factor, beta
chr16_+_3550924 0.10 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
CLUAP1
clusterin associated protein 1
chr2_-_201828356 0.09 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr6_+_122720681 0.09 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr19_+_19144384 0.09 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chrX_+_80457442 0.09 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr21_+_17214724 0.09 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr22_+_42017459 0.09 ENST00000405878.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chrX_-_134478012 0.09 ENST00000370766.3
ZNF75D
zinc finger protein 75D
chr4_-_76862117 0.09 ENST00000507956.1
ENST00000507187.2
ENST00000399497.3
ENST00000286733.4
NAAA
N-acylethanolamine acid amidase
chr19_+_17326521 0.09 ENST00000593597.1
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr3_-_112693759 0.08 ENST00000440122.2
ENST00000490004.1
CD200R1
CD200 receptor 1
chr2_+_234580499 0.08 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_+_234580525 0.08 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr14_+_105266933 0.08 ENST00000555360.1
ZBTB42
zinc finger and BTB domain containing 42
chr10_+_97515409 0.08 ENST00000371207.3
ENST00000543964.1
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr17_+_79859985 0.08 ENST00000333383.7
NPB
neuropeptide B
chr3_+_130648842 0.08 ENST00000508297.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr5_-_146833803 0.08 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr19_+_36203830 0.08 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr8_+_20054878 0.08 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr8_-_57906362 0.08 ENST00000262644.4
IMPAD1
inositol monophosphatase domain containing 1
chr1_+_233749739 0.08 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr4_-_70080449 0.07 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr6_+_10585979 0.07 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr15_-_80263506 0.07 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr2_-_74007193 0.07 ENST00000377706.4
ENST00000443070.1
ENST00000272444.3
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr2_-_241500447 0.07 ENST00000536462.1
ENST00000405002.1
ENST00000441168.1
ENST00000403283.1
ANKMY1
ankyrin repeat and MYND domain containing 1
chr11_-_8615720 0.07 ENST00000358872.3
ENST00000454443.2
STK33
serine/threonine kinase 33
chr20_+_10415931 0.07 ENST00000334534.5
SLX4IP
SLX4 interacting protein
chr5_-_36152031 0.06 ENST00000296603.4
LMBRD2
LMBR1 domain containing 2
chr21_-_34915084 0.06 ENST00000426819.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr1_+_159175201 0.06 ENST00000368121.2
DARC
Duffy blood group, atypical chemokine receptor
chr13_+_53226963 0.06 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr20_-_30311703 0.06 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1
BCL2-like 1
chr4_+_146403912 0.06 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr19_-_45826125 0.06 ENST00000221476.3
CKM
creatine kinase, muscle
chr1_-_156722015 0.06 ENST00000368209.5
HDGF
hepatoma-derived growth factor
chr21_-_34915123 0.06 ENST00000438059.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr19_+_7459998 0.06 ENST00000319670.9
ENST00000599752.1
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr18_+_52385068 0.05 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr17_+_40714092 0.05 ENST00000420359.1
ENST00000449624.1
ENST00000585811.1
ENST00000585909.1
ENST00000586771.1
ENST00000421097.2
ENST00000591779.1
ENST00000587858.1
ENST00000587214.1
ENST00000587157.1
ENST00000590958.1
ENST00000393818.2
COASY
CoA synthase
chr3_-_58613323 0.05 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr15_-_60683326 0.05 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr16_+_83841448 0.05 ENST00000433866.2
HSBP1
heat shock factor binding protein 1
chr3_-_179322416 0.05 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr15_+_75491213 0.05 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr4_-_85771168 0.05 ENST00000514071.1
WDFY3
WD repeat and FYVE domain containing 3
chr11_-_77705687 0.04 ENST00000529807.1
ENST00000527522.1
ENST00000534064.1
INTS4
integrator complex subunit 4
chrX_+_11776278 0.04 ENST00000312196.4
ENST00000337339.2
MSL3
male-specific lethal 3 homolog (Drosophila)
chr9_+_33025209 0.04 ENST00000330899.4
ENST00000544625.1
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr15_+_58724184 0.04 ENST00000433326.2
LIPC
lipase, hepatic
chr19_-_13068012 0.04 ENST00000316939.1
GADD45GIP1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr1_+_161736072 0.04 ENST00000367942.3
ATF6
activating transcription factor 6
chr5_+_36152163 0.04 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr1_-_35450897 0.04 ENST00000373337.3
ZMYM6NB
ZMYM6 neighbor
chr13_-_72441315 0.04 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr2_+_37458776 0.04 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr12_-_58165870 0.03 ENST00000257848.7
METTL1
methyltransferase like 1
chr12_+_58166370 0.03 ENST00000300209.8
METTL21B
methyltransferase like 21B
chr2_-_74735707 0.03 ENST00000233630.6
PCGF1
polycomb group ring finger 1
chr7_-_43769066 0.03 ENST00000223336.6
ENST00000310564.6
ENST00000431651.1
ENST00000415798.1
COA1
cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
chr7_-_46521173 0.03 ENST00000440935.1
AC004869.2
AC004869.2
chr9_+_112542591 0.03 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr15_+_66161792 0.03 ENST00000564910.1
ENST00000261890.2
RAB11A
RAB11A, member RAS oncogene family
chr1_+_196857144 0.03 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr1_-_71546690 0.03 ENST00000254821.6
ZRANB2
zinc finger, RAN-binding domain containing 2
chr12_+_58166431 0.03 ENST00000333012.5
METTL21B
methyltransferase like 21B
chr4_-_185733394 0.02 ENST00000504342.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr5_-_125930877 0.02 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr1_+_232940643 0.02 ENST00000418460.1
MAP10
microtubule-associated protein 10
chr12_-_14967095 0.02 ENST00000316048.2
SMCO3
single-pass membrane protein with coiled-coil domains 3
chr15_-_29745003 0.02 ENST00000560082.1
FAM189A1
family with sequence similarity 189, member A1
chr7_-_76955563 0.02 ENST00000441833.2
GSAP
gamma-secretase activating protein
chr5_-_140053152 0.02 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr12_-_95467356 0.02 ENST00000393101.3
ENST00000333003.5
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr4_-_122791583 0.02 ENST00000506636.1
ENST00000264499.4
BBS7
Bardet-Biedl syndrome 7
chr21_-_34915147 0.02 ENST00000381831.3
ENST00000381839.3
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chrX_+_148793714 0.01 ENST00000355220.5
MAGEA11
melanoma antigen family A, 11
chr4_+_151503077 0.01 ENST00000317605.4
MAB21L2
mab-21-like 2 (C. elegans)
chr3_-_179322436 0.01 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr16_+_89696692 0.01 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr2_+_37458904 0.01 ENST00000416653.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr8_-_80942061 0.01 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr1_-_10003372 0.01 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC
leucine zipper and CTNNBIP1 domain containing
chr13_+_103498143 0.01 ENST00000535557.1
ERCC5
excision repair cross-complementing rodent repair deficiency, complementation group 5

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.5 2.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.4 1.1 GO:0016488 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.2 0.8 GO:1901143 insulin catabolic process(GO:1901143)
0.2 0.8 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.5 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 1.0 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.4 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 0.2 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.3 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 1.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.5 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.5 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.5 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 1.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0052364 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.0 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.4 1.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.3 0.8 GO:0031626 beta-endorphin binding(GO:0031626)
0.3 1.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.5 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.2 1.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0015039 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 1.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.3 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 2.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 2.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex