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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OTX2_CRX

Z-value: 0.60

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Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.12 orthodenticle homeobox 2
CRX
ENSG00000105392.11 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CRXhg19_v2_chr19_+_48325097_483252110.541.3e-02Click!

Activity profile of OTX2_CRX motif

Sorted Z-values of OTX2_CRX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_61522844 2.45 ENST00000265460.5
MYRF
myelin regulatory factor
chr15_-_27184664 2.24 ENST00000541819.2
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_+_85673868 1.76 ENST00000316824.3
ALX1
ALX homeobox 1
chr15_-_74495188 1.73 ENST00000563965.1
ENST00000395105.4
STRA6
stimulated by retinoic acid 6
chr16_-_31076332 1.38 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr3_-_149095652 1.37 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr14_-_95236551 1.37 ENST00000238558.3
GSC
goosecoid homeobox
chr17_-_46690839 1.33 ENST00000498634.2
HOXB8
homeobox B8
chr3_+_49058444 1.31 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr7_-_33080506 1.28 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr17_-_46692287 1.22 ENST00000239144.4
HOXB8
homeobox B8
chr12_+_53693466 1.20 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr7_-_128415844 1.17 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr19_+_46001697 1.15 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr12_+_53693812 1.11 ENST00000549488.1
C12orf10
chromosome 12 open reading frame 10
chr15_-_74494779 1.09 ENST00000571341.1
STRA6
stimulated by retinoic acid 6
chr9_-_39288092 1.08 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3
contactin associated protein-like 3
chr1_+_169079823 1.07 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_207277590 1.06 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr8_-_25281747 1.05 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr1_+_114522049 1.04 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr17_-_4689649 1.04 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr16_-_31076273 1.02 ENST00000426488.2
ZNF668
zinc finger protein 668
chr2_-_175711133 1.01 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr3_-_49058479 0.99 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr17_+_43318434 0.92 ENST00000587489.1
FMNL1
formin-like 1
chr19_+_48325097 0.84 ENST00000221996.7
ENST00000539067.1
CRX
cone-rod homeobox
chr19_+_2476116 0.83 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr16_+_81272287 0.80 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr10_+_104178946 0.79 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr5_-_41510656 0.76 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr17_+_68100989 0.74 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr12_+_104697504 0.74 ENST00000527879.1
EID3
EP300 interacting inhibitor of differentiation 3
chr3_+_49057876 0.74 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr5_+_133451254 0.72 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr13_-_31191642 0.72 ENST00000405805.1
HMGB1
high mobility group box 1
chr15_+_44092784 0.70 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr1_+_164528866 0.69 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr4_+_129730779 0.65 ENST00000226319.6
PHF17
jade family PHD finger 1
chr19_+_39989535 0.65 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr1_+_244214577 0.63 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr4_+_129730947 0.60 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr17_-_4689727 0.60 ENST00000328739.5
ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr4_+_124571409 0.60 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr1_+_11751748 0.59 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chr19_+_39989580 0.59 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chrX_-_10588595 0.58 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr19_-_44123734 0.55 ENST00000598676.1
ZNF428
zinc finger protein 428
chr14_-_101034407 0.53 ENST00000443071.2
ENST00000557378.1
BEGAIN
brain-enriched guanylate kinase-associated
chr17_+_68101117 0.53 ENST00000587698.1
ENST00000587892.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr15_-_44092295 0.53 ENST00000249714.3
ENST00000299969.6
ENST00000319327.6
SERINC4
serine incorporator 4
chr19_-_11457162 0.51 ENST00000590482.1
TMEM205
transmembrane protein 205
chr19_+_50183032 0.51 ENST00000527412.1
PRMT1
protein arginine methyltransferase 1
chr14_-_58894332 0.50 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr19_+_40877583 0.50 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr1_-_231560790 0.49 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr5_-_41510725 0.49 ENST00000328457.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr10_+_102505468 0.48 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr15_+_41221536 0.48 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr19_-_44124019 0.47 ENST00000300811.3
ZNF428
zinc finger protein 428
chr2_-_119605253 0.46 ENST00000295206.6
EN1
engrailed homeobox 1
chr18_-_56985776 0.46 ENST00000587244.1
CPLX4
complexin 4
chr16_-_325910 0.45 ENST00000359740.5
ENST00000316163.5
ENST00000431291.2
ENST00000397770.3
ENST00000397768.3
RGS11
regulator of G-protein signaling 11
chr6_-_31697563 0.45 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr14_-_22005062 0.45 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr1_-_11751665 0.45 ENST00000376667.3
ENST00000235310.3
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr14_+_96722152 0.45 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr1_-_11751529 0.44 ENST00000376672.1
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr4_+_129730839 0.42 ENST00000511647.1
PHF17
jade family PHD finger 1
chr5_-_58882219 0.42 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_30658745 0.42 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chr15_-_52483566 0.42 ENST00000261837.7
GNB5
guanine nucleotide binding protein (G protein), beta 5
chrX_+_69509927 0.42 ENST00000374403.3
KIF4A
kinesin family member 4A
chr19_+_11457175 0.41 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr3_-_179691866 0.41 ENST00000464614.1
ENST00000476138.1
ENST00000463761.1
PEX5L
peroxisomal biogenesis factor 5-like
chr2_-_225362533 0.41 ENST00000451538.1
CUL3
cullin 3
chr2_-_175499294 0.41 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr6_-_31697255 0.40 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_59066452 0.40 ENST00000312547.2
CHMP2A
charged multivesicular body protein 2A
chr1_+_17248418 0.39 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr3_-_179692042 0.39 ENST00000468741.1
PEX5L
peroxisomal biogenesis factor 5-like
chr12_+_78224667 0.38 ENST00000549464.1
NAV3
neuron navigator 3
chrX_-_10588459 0.38 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr22_-_38480100 0.38 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr2_+_128175997 0.37 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr3_-_149388682 0.37 ENST00000475579.1
WWTR1
WW domain containing transcription regulator 1
chr2_+_120770581 0.37 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr7_+_93535817 0.36 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr3_-_186262166 0.36 ENST00000307944.5
CRYGS
crystallin, gamma S
chr17_-_43210580 0.35 ENST00000538093.1
ENST00000590644.1
PLCD3
phospholipase C, delta 3
chr7_-_100171270 0.35 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr6_-_35480640 0.34 ENST00000428978.1
ENST00000322263.4
TULP1
tubby like protein 1
chr20_+_42984330 0.34 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr17_-_48207157 0.34 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr10_+_103986085 0.33 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr1_+_207277632 0.33 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr2_+_85822839 0.33 ENST00000441634.1
RNF181
ring finger protein 181
chr7_-_97881429 0.33 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr2_-_121223697 0.32 ENST00000593290.1
FLJ14816
long intergenic non-protein coding RNA 1101
chr3_-_137851220 0.32 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr22_-_41258074 0.32 ENST00000307221.4
DNAJB7
DnaJ (Hsp40) homolog, subfamily B, member 7
chr14_-_101034811 0.32 ENST00000553553.1
BEGAIN
brain-enriched guanylate kinase-associated
chr7_+_93535866 0.32 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chrX_-_100129128 0.32 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr11_-_8680383 0.31 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr12_-_90049828 0.31 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chrX_+_153769409 0.31 ENST00000440286.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr18_-_64271363 0.30 ENST00000262150.2
CDH19
cadherin 19, type 2
chr3_+_49059038 0.30 ENST00000451378.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr15_+_33603147 0.30 ENST00000415757.3
ENST00000389232.4
RYR3
ryanodine receptor 3
chr1_+_18957500 0.30 ENST00000375375.3
PAX7
paired box 7
chrX_-_21676442 0.30 ENST00000379499.2
KLHL34
kelch-like family member 34
chr9_+_103204553 0.29 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_-_17500294 0.29 ENST00000439046.1
AC019117.2
AC019117.2
chr9_-_131486367 0.29 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr6_+_34433844 0.28 ENST00000244458.2
ENST00000374043.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr8_-_80993010 0.28 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr11_+_72975524 0.28 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_+_100054606 0.27 ENST00000369215.4
PRDM13
PR domain containing 13
chr13_+_36050881 0.27 ENST00000537702.1
NBEA
neurobeachin
chr8_-_145701718 0.27 ENST00000377317.4
FOXH1
forkhead box H1
chr11_-_62437486 0.27 ENST00000528115.1
C11orf48
chromosome 11 open reading frame 48
chrX_-_124097620 0.27 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chrM_+_9207 0.27 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr8_+_86999516 0.27 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr17_+_4643337 0.27 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr1_+_164529004 0.26 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr10_+_95372289 0.26 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chrY_+_16634483 0.26 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr4_+_129731074 0.26 ENST00000512960.1
ENST00000503785.1
ENST00000514740.1
PHF17
jade family PHD finger 1
chr1_-_117664317 0.25 ENST00000256649.4
ENST00000369464.3
ENST00000485032.1
TRIM45
tripartite motif containing 45
chr12_-_52604607 0.25 ENST00000551894.1
ENST00000553017.1
C12orf80
chromosome 12 open reading frame 80
chrX_+_153769446 0.25 ENST00000422680.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr2_+_183943464 0.25 ENST00000354221.4
DUSP19
dual specificity phosphatase 19
chr18_-_56985873 0.25 ENST00000299721.3
CPLX4
complexin 4
chrX_+_129473916 0.25 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_-_78400598 0.24 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_-_119077695 0.24 ENST00000371410.3
NKAP
NFKB activating protein
chr10_-_21806759 0.24 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr7_+_28452130 0.24 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr21_-_19775973 0.24 ENST00000284885.3
TMPRSS15
transmembrane protease, serine 15
chr12_-_90049878 0.24 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr18_-_40857493 0.23 ENST00000255224.3
SYT4
synaptotagmin IV
chr3_-_112218378 0.23 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr1_+_153651078 0.23 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr17_+_4643300 0.22 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr10_-_62761188 0.22 ENST00000357917.4
RHOBTB1
Rho-related BTB domain containing 1
chr11_+_72975578 0.22 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_+_55505184 0.22 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr21_+_33245548 0.22 ENST00000270112.2
HUNK
hormonally up-regulated Neu-associated kinase
chr19_+_56166360 0.22 ENST00000308924.4
U2AF2
U2 small nuclear RNA auxiliary factor 2
chr2_-_136873735 0.22 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chrX_-_110655306 0.22 ENST00000371993.2
DCX
doublecortin
chr20_-_31124186 0.22 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr12_+_7941989 0.22 ENST00000229307.4
NANOG
Nanog homeobox
chr10_-_94003003 0.21 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr1_-_26633480 0.21 ENST00000450041.1
UBXN11
UBX domain protein 11
chr11_-_75017734 0.21 ENST00000532525.1
ARRB1
arrestin, beta 1
chr11_+_72975559 0.21 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_-_165414414 0.21 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr22_-_38380543 0.21 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr2_+_85822857 0.21 ENST00000306368.4
ENST00000414390.1
ENST00000456023.1
RNF181
ring finger protein 181
chr3_-_112218205 0.21 ENST00000383680.4
BTLA
B and T lymphocyte associated
chr2_+_33661382 0.20 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_-_77072085 0.20 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
TBCA
tubulin folding cofactor A
chrX_+_28605516 0.20 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr10_+_35464513 0.20 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
CREM
cAMP responsive element modulator
chr4_+_70894130 0.19 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr10_+_95848824 0.19 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr12_+_58138664 0.19 ENST00000257910.3
TSPAN31
tetraspanin 31
chr1_-_150208498 0.19 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_13248598 0.19 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr7_-_128171123 0.18 ENST00000608477.1
RP11-212P7.2
RP11-212P7.2
chr10_-_76868931 0.18 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr3_+_129247479 0.18 ENST00000296271.3
RHO
rhodopsin
chr9_-_95244781 0.18 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr12_-_13248562 0.18 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr10_+_134150835 0.17 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr10_-_76868866 0.17 ENST00000607487.1
DUSP13
dual specificity phosphatase 13
chr10_-_21186144 0.17 ENST00000377119.1
NEBL
nebulette
chr2_-_200715573 0.17 ENST00000420922.2
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr12_-_53171128 0.17 ENST00000332411.2
KRT76
keratin 76
chrX_-_64754611 0.17 ENST00000374807.5
ENST00000374811.3
ENST00000374804.5
ENST00000312391.8
LAS1L
LAS1-like (S. cerevisiae)
chr12_-_13248705 0.17 ENST00000396310.2
GSG1
germ cell associated 1
chr3_-_32612263 0.17 ENST00000432458.2
ENST00000424991.1
ENST00000273130.4
DYNC1LI1
dynein, cytoplasmic 1, light intermediate chain 1
chr5_+_140345820 0.17 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr17_-_46692457 0.17 ENST00000468443.1
HOXB8
homeobox B8
chr9_+_18474098 0.16 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr5_+_161494770 0.16 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chrX_+_100645812 0.16 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr14_+_88471468 0.16 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chrX_-_6146876 0.16 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr3_-_190580404 0.15 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr2_-_55237484 0.15 ENST00000394609.2
RTN4
reticulon 4
chr18_-_64271316 0.15 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr15_-_65407524 0.15 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr15_+_79603404 0.15 ENST00000299705.5
TMED3
transmembrane emp24 protein transport domain containing 3
chr15_-_35047166 0.15 ENST00000290374.4
GJD2
gap junction protein, delta 2, 36kDa
chr3_-_54962100 0.15 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr2_-_61765315 0.15 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 1.1 GO:1990637 response to prolactin(GO:1990637)
0.2 2.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 0.7 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.2 1.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 0.5 GO:0021650 vestibulocochlear nerve formation(GO:0021650) regulation of metanephros size(GO:0035566)
0.2 0.5 GO:0061074 regulation of neural retina development(GO:0061074)
0.2 1.1 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 1.4 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 3.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.0 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.5 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.8 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 2.4 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 2.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.5 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.4 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 1.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.4 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.3 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 1.4 GO:0014029 neural crest formation(GO:0014029)
0.1 1.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.5 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.8 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.8 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.7 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.5 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.3 GO:1901631 positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.8 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.9 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.5 GO:0015825 L-serine transport(GO:0015825)
0.0 1.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.4 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 2.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.3 GO:0060348 bone development(GO:0060348)
0.0 0.3 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.3 GO:0032127 dense core granule membrane(GO:0032127) microvesicle(GO:1990742)
0.1 2.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 1.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.9 GO:0032059 bleb(GO:0032059)
0.0 1.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 2.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.6 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.7 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 1.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.9 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.3 REACTOME OPSINS Genes involved in Opsins
0.1 2.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)