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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OVOL1

Z-value: 0.35

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Transcription factors associated with OVOL1

Gene Symbol Gene ID Gene Info
OVOL1
ENSG00000172818.5 ovo like transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OVOL1hg19_v2_chr11_+_65554493_65554546-0.992.0e-15Click!

Activity profile of OVOL1 motif

Sorted Z-values of OVOL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_123301012 1.34 ENST00000533341.1
AP000783.1
Uncharacterized protein
chr15_-_64386120 0.75 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr10_-_21786179 0.71 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr15_-_64385981 0.60 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr19_+_6772710 0.54 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
VAV1
vav 1 guanine nucleotide exchange factor
chr3_-_149093499 0.49 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr5_-_16509101 0.34 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr11_-_75017734 0.31 ENST00000532525.1
ARRB1
arrestin, beta 1
chr5_+_140261703 0.30 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr10_-_73848531 0.26 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_73848764 0.24 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr17_-_7145475 0.24 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr15_+_75335604 0.20 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr7_-_148581360 0.18 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr10_-_73848086 0.11 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_-_183387064 0.10 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_183387430 0.09 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr14_+_29241910 0.07 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr16_-_67260691 0.07 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr3_-_165555200 0.07 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr2_-_183387283 0.05 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr5_+_72112418 0.03 ENST00000454282.1
TNPO1
transportin 1
chr12_+_96196875 0.03 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr4_+_39408470 0.02 ENST00000257408.4
KLB
klotho beta
chr1_-_98515395 0.02 ENST00000424528.2
MIR137HG
MIR137 host gene (non-protein coding)
chr5_+_140739537 0.02 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr6_-_84419101 0.02 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
SNAP91
synaptosomal-associated protein, 91kDa
chr7_-_38389573 0.01 ENST00000390344.2
TRGV5
T cell receptor gamma variable 5
chr19_-_46296011 0.00 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing

Network of associatons between targets according to the STRING database.

First level regulatory network of OVOL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.5 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway