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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PAX3

Z-value: 0.56

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Transcription factors associated with PAX3

Gene Symbol Gene ID Gene Info
PAX3
ENSG00000135903.14 paired box 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX3hg19_v2_chr2_-_223163465_223163730-0.454.6e-02Click!

Activity profile of PAX3 motif

Sorted Z-values of PAX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_32908792 1.71 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr11_-_615570 1.56 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr11_-_615942 1.46 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr17_+_4855053 1.23 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr6_-_32908765 1.19 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr11_+_66624527 1.13 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr2_+_152214098 1.10 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr10_+_104178946 1.09 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr19_-_42463418 1.05 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1
Rab acceptor 1 (prenylated)
chr12_-_58131931 1.02 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chrX_+_38420623 0.97 ENST00000378482.2
TSPAN7
tetraspanin 7
chr19_-_41903161 0.92 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr2_+_183989083 0.91 ENST00000295119.4
NUP35
nucleoporin 35kDa
chr11_-_73694346 0.90 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chrX_+_38420783 0.86 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr2_+_240323439 0.84 ENST00000428471.1
ENST00000413029.1
AC062017.1
Uncharacterized protein
chrX_+_70364667 0.83 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr7_-_107883678 0.82 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr11_+_66059339 0.82 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr3_+_160117062 0.79 ENST00000497311.1
SMC4
structural maintenance of chromosomes 4
chr2_+_183989157 0.75 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr11_-_9482010 0.74 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr12_+_7060508 0.71 ENST00000541698.1
ENST00000542462.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr19_+_55851221 0.70 ENST00000255613.3
ENST00000539076.1
SUV420H2
AC020922.1
suppressor of variegation 4-20 homolog 2 (Drosophila)
Uncharacterized protein
chr17_+_37356528 0.69 ENST00000225430.4
RPL19
ribosomal protein L19
chr12_-_69080590 0.69 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
RP11-637A17.2
chr9_-_104160872 0.67 ENST00000539624.1
ENST00000374865.4
MRPL50
mitochondrial ribosomal protein L50
chr17_-_38574169 0.66 ENST00000423485.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr3_+_160117087 0.65 ENST00000357388.3
SMC4
structural maintenance of chromosomes 4
chr8_+_145159376 0.64 ENST00000322428.5
MAF1
MAF1 homolog (S. cerevisiae)
chr1_+_26496362 0.63 ENST00000374266.5
ENST00000270812.5
ZNF593
zinc finger protein 593
chr12_+_7060414 0.63 ENST00000538715.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr15_-_80263506 0.63 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chrX_-_15872914 0.62 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr7_+_99816859 0.62 ENST00000317271.2
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr12_+_7060432 0.61 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr5_+_178977546 0.61 ENST00000319449.4
ENST00000377001.2
RUFY1
RUN and FYVE domain containing 1
chr10_+_91087651 0.59 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr8_+_145159415 0.59 ENST00000534585.1
MAF1
MAF1 homolog (S. cerevisiae)
chr11_+_65122216 0.59 ENST00000309880.5
TIGD3
tigger transposable element derived 3
chr5_+_159343688 0.59 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr17_+_37356555 0.54 ENST00000579374.1
RPL19
ribosomal protein L19
chr10_-_102289611 0.54 ENST00000299166.4
ENST00000370320.4
ENST00000531258.1
ENST00000370322.1
ENST00000535773.1
NDUFB8
SEC31B
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
SEC31 homolog B (S. cerevisiae)
chrX_-_53461305 0.53 ENST00000168216.6
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chrX_+_102883887 0.53 ENST00000372625.3
ENST00000372624.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr17_+_37356586 0.53 ENST00000579260.1
ENST00000582193.1
RPL19
ribosomal protein L19
chr14_+_23938891 0.52 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
NGDN
neuroguidin, EIF4E binding protein
chr19_+_35168567 0.51 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr15_+_99791567 0.50 ENST00000558879.1
ENST00000301981.3
ENST00000422500.2
ENST00000447360.2
ENST00000442993.2
LRRC28
leucine rich repeat containing 28
chr17_-_34417479 0.49 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr20_-_23807358 0.49 ENST00000304725.2
CST2
cystatin SA
chr19_-_40596828 0.49 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
ZNF780A
zinc finger protein 780A
chr12_-_89919965 0.48 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr22_-_21581926 0.48 ENST00000401924.1
GGT2
gamma-glutamyltransferase 2
chr4_+_14113592 0.47 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chr8_-_145159083 0.47 ENST00000398712.2
SHARPIN
SHANK-associated RH domain interactor
chr19_+_35168547 0.46 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
ZNF302
zinc finger protein 302
chr22_+_42372764 0.46 ENST00000396426.3
ENST00000406029.1
SEPT3
septin 3
chr1_+_1222489 0.46 ENST00000379099.3
SCNN1D
sodium channel, non-voltage-gated 1, delta subunit
chr15_+_99791716 0.46 ENST00000558172.1
ENST00000561276.1
ENST00000331450.5
LRRC28
leucine rich repeat containing 28
chrX_+_102883620 0.45 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr19_+_35168633 0.45 ENST00000505365.2
ZNF302
zinc finger protein 302
chr16_-_21849091 0.44 ENST00000537951.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr5_-_87516448 0.42 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr12_+_69080734 0.42 ENST00000378905.2
NUP107
nucleoporin 107kDa
chr2_+_183982238 0.40 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
NUP35
nucleoporin 35kDa
chr9_-_91793675 0.39 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr14_-_24584138 0.38 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr11_+_57791353 0.37 ENST00000335397.3
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr9_+_131549483 0.37 ENST00000372648.5
ENST00000539497.1
TBC1D13
TBC1 domain family, member 13
chrX_-_53461288 0.35 ENST00000375298.4
ENST00000375304.5
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr5_+_140480083 0.35 ENST00000231130.2
PCDHB3
protocadherin beta 3
chr19_+_52693259 0.35 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr10_-_1094337 0.35 ENST00000427898.1
IDI1
isopentenyl-diphosphate delta isomerase 1
chr4_-_170924888 0.34 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr19_+_4343584 0.34 ENST00000596722.1
MPND
MPN domain containing
chr10_+_134150835 0.33 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr16_-_71523179 0.33 ENST00000564230.1
ENST00000565637.1
ZNF19
zinc finger protein 19
chr8_-_81083731 0.32 ENST00000379096.5
TPD52
tumor protein D52
chr1_+_101185290 0.31 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
VCAM1
vascular cell adhesion molecule 1
chr17_+_7835419 0.31 ENST00000576538.1
ENST00000380262.3
ENST00000563694.1
ENST00000380255.3
ENST00000570782.1
CNTROB
centrobin, centrosomal BRCA2 interacting protein
chr7_-_148580563 0.30 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_-_145715565 0.30 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr7_-_50633078 0.29 ENST00000444124.2
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr4_-_48116540 0.28 ENST00000506073.1
TXK
TXK tyrosine kinase
chr20_-_17511962 0.27 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr14_+_23067166 0.27 ENST00000216327.6
ENST00000542041.1
ABHD4
abhydrolase domain containing 4
chr19_-_19626351 0.27 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr15_+_45722727 0.26 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr9_+_131549610 0.26 ENST00000223865.8
TBC1D13
TBC1 domain family, member 13
chr3_-_151176497 0.26 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chrX_+_153770421 0.26 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr15_+_43622843 0.25 ENST00000428046.3
ENST00000422466.2
ENST00000389651.4
ADAL
adenosine deaminase-like
chrX_+_47077680 0.25 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr17_+_32597232 0.25 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
CCL7
chemokine (C-C motif) ligand 7
chr12_+_8309630 0.24 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr11_+_313503 0.24 ENST00000528780.1
ENST00000328221.5
IFITM1
interferon induced transmembrane protein 1
chr19_+_32836499 0.24 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chrX_+_37850026 0.24 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr7_+_29519486 0.23 ENST00000409041.4
CHN2
chimerin 2
chr2_-_227050079 0.23 ENST00000423838.1
AC068138.1
AC068138.1
chr1_+_201592013 0.23 ENST00000593583.1
AC096677.1
Uncharacterized protein ENSP00000471857
chr4_+_105828537 0.22 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr16_-_21416640 0.22 ENST00000542817.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr11_+_73358594 0.22 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr19_+_4343691 0.22 ENST00000597036.1
MPND
MPN domain containing
chr16_-_18468926 0.21 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chrX_+_1734051 0.20 ENST00000381229.4
ENST00000381233.3
ASMT
acetylserotonin O-methyltransferase
chr4_+_105828492 0.19 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr6_-_24721054 0.19 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr3_+_160117418 0.19 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chrX_-_13835398 0.19 ENST00000475307.1
GPM6B
glycoprotein M6B
chr5_-_179498703 0.18 ENST00000522208.2
RNF130
ring finger protein 130
chr4_+_15376165 0.18 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr12_+_9142131 0.18 ENST00000356986.3
ENST00000266551.4
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr2_-_68479614 0.18 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr16_+_27214802 0.18 ENST00000380948.2
ENST00000286096.4
KDM8
lysine (K)-specific demethylase 8
chr15_+_51973550 0.18 ENST00000220478.3
SCG3
secretogranin III
chr12_-_89920030 0.18 ENST00000413530.1
ENST00000547474.1
GALNT4
POC1B-GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr3_-_178103144 0.17 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr16_-_71523236 0.17 ENST00000288177.5
ENST00000569072.1
ZNF19
zinc finger protein 19
chr19_-_57183114 0.17 ENST00000537055.2
ENST00000601659.1
ZNF835
zinc finger protein 835
chr11_+_73358690 0.16 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chrX_-_13835461 0.16 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr7_+_129015671 0.15 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr9_-_132515302 0.15 ENST00000340607.4
PTGES
prostaglandin E synthase
chrX_+_103217207 0.14 ENST00000563257.1
ENST00000540220.1
ENST00000436583.1
ENST00000567181.1
ENST00000569577.1
TMSB15B
thymosin beta 15B
chr17_+_80816395 0.14 ENST00000576160.2
ENST00000571712.1
TBCD
tubulin folding cofactor D
chr22_+_22723969 0.14 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr4_-_104119488 0.13 ENST00000514974.1
CENPE
centromere protein E, 312kDa
chr3_+_14716606 0.13 ENST00000253697.3
ENST00000435614.1
ENST00000412910.1
C3orf20
chromosome 3 open reading frame 20
chr7_-_142659388 0.12 ENST00000476829.1
ENST00000467543.1
KEL
Kell blood group, metallo-endopeptidase
chr5_+_147648393 0.12 ENST00000511106.1
ENST00000398450.4
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr5_+_127039075 0.12 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr2_-_128051708 0.12 ENST00000285398.2
ERCC3
excision repair cross-complementing rodent repair deficiency, complementation group 3
chr15_+_38226827 0.12 ENST00000559502.1
ENST00000558148.1
ENST00000558158.1
TMCO5A
transmembrane and coiled-coil domains 5A
chr2_-_128051670 0.12 ENST00000493187.2
ERCC3
excision repair cross-complementing rodent repair deficiency, complementation group 3
chr1_+_99729813 0.11 ENST00000457765.1
LPPR4
Lipid phosphate phosphatase-related protein type 4
chr10_-_104178857 0.11 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr8_-_121825088 0.11 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr22_+_27068704 0.11 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5
CTA-211A9.5
chr10_-_52008313 0.11 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr16_-_75018968 0.10 ENST00000262144.6
WDR59
WD repeat domain 59
chr1_-_155214436 0.10 ENST00000327247.5
GBA
glucosidase, beta, acid
chr8_+_104426942 0.10 ENST00000297579.5
DCAF13
DDB1 and CUL4 associated factor 13
chr2_-_44065889 0.10 ENST00000543989.1
ENST00000405322.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr5_-_177180297 0.10 ENST00000504518.1
FAM153A
family with sequence similarity 153, member A
chr1_-_9086404 0.10 ENST00000400906.1
SLC2A7
solute carrier family 2 (facilitated glucose transporter), member 7
chr2_-_183106641 0.10 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chrX_+_135230712 0.10 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr6_+_1080164 0.09 ENST00000314040.1
AL033381.1
Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr3_+_169755919 0.09 ENST00000492492.1
GPR160
G protein-coupled receptor 160
chr3_+_112709804 0.09 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr12_-_10562356 0.09 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chrY_+_20708557 0.09 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr5_-_180688105 0.09 ENST00000327767.4
TRIM52
tripartite motif containing 52
chr9_+_131903916 0.09 ENST00000419582.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chrX_+_47077632 0.09 ENST00000457458.2
CDK16
cyclin-dependent kinase 16
chr6_+_10633993 0.08 ENST00000417671.1
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr15_-_52861394 0.08 ENST00000563277.1
ENST00000566423.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr9_-_13175823 0.08 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chrY_-_20935572 0.08 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr17_-_7835228 0.07 ENST00000303731.4
ENST00000571947.1
ENST00000540486.1
ENST00000572656.1
TRAPPC1
trafficking protein particle complex 1
chr1_+_84630053 0.07 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_219524379 0.07 ENST00000443791.1
ENST00000359273.3
ENST00000392109.1
ENST00000392110.2
ENST00000423377.1
ENST00000392111.2
ENST00000412366.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr15_+_51973680 0.07 ENST00000542355.2
SCG3
secretogranin III
chr10_+_90521163 0.06 ENST00000404459.1
LIPN
lipase, family member N
chr3_+_38307313 0.06 ENST00000450935.2
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr15_-_43622736 0.06 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2
leucine carboxyl methyltransferase 2
chrX_-_118699325 0.06 ENST00000320339.4
ENST00000371594.4
ENST00000536133.1
CXorf56
chromosome X open reading frame 56
chr6_-_30815936 0.06 ENST00000442852.1
XXbac-BPG27H4.8
XXbac-BPG27H4.8
chr15_+_51973708 0.06 ENST00000558709.1
SCG3
secretogranin III
chr14_+_45464658 0.06 ENST00000555874.1
FAM179B
family with sequence similarity 179, member B
chr5_-_119669160 0.06 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr13_+_96085847 0.05 ENST00000376873.3
CLDN10
claudin 10
chr10_-_106098162 0.05 ENST00000337478.1
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr7_-_103629963 0.05 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr4_-_168155417 0.05 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr4_-_168155577 0.05 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr3_-_110612323 0.05 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr8_-_10512569 0.05 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr19_-_55574538 0.05 ENST00000415061.3
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr19_-_46296011 0.05 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr8_+_125463048 0.05 ENST00000328599.3
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr6_+_10634158 0.05 ENST00000379591.3
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr1_+_203444887 0.04 ENST00000343110.2
PRELP
proline/arginine-rich end leucine-rich repeat protein
chr6_-_9939552 0.04 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chrX_-_73834449 0.04 ENST00000332687.6
ENST00000349225.2
RLIM
ring finger protein, LIM domain interacting
chr1_-_108786689 0.04 ENST00000415641.3
NBPF4
neuroblastoma breakpoint family, member 4
chr7_+_116502527 0.04 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr16_-_52640834 0.03 ENST00000510238.3
CASC16
cancer susceptibility candidate 16 (non-protein coding)
chr9_-_88897426 0.03 ENST00000375991.4
ENST00000326094.4
ISCA1
iron-sulfur cluster assembly 1
chr12_-_75603643 0.03 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr22_+_20905422 0.03 ENST00000424287.1
ENST00000423862.1
MED15
mediator complex subunit 15
chr19_+_31658405 0.03 ENST00000589511.1
CTC-439O9.3
CTC-439O9.3
chr10_+_118305435 0.03 ENST00000369221.2
PNLIP
pancreatic lipase
chr1_+_247670415 0.03 ENST00000366491.2
ENST00000366489.1
ENST00000526896.1
GCSAML
germinal center-associated, signaling and motility-like
chr21_+_34775181 0.03 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr17_-_60883993 0.03 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr8_-_81083618 0.03 ENST00000520795.1
TPD52
tumor protein D52

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.6 3.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.3 2.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 1.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.6 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 0.9 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 0.9 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.2 0.9 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 1.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.4 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.3 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.3 GO:0050992 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.1 0.3 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.9 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.8 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 1.8 GO:0097421 liver regeneration(GO:0097421)
0.0 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 1.1 GO:0030728 ovulation(GO:0030728)
0.0 0.5 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 2.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.6 GO:0000796 condensin complex(GO:0000796)
0.1 0.9 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 1.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.2 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 1.2 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.2 0.7 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 0.6 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.6 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 0.3 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.1 2.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 2.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.9 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 2.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 3.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID EPO PATHWAY EPO signaling pathway
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 3.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 2.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 3.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones