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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PAX4

Z-value: 0.86

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Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
PAX4
ENSG00000106331.10 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg19_v2_chr7_-_127255982_127255982-0.165.0e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_106163626 5.47 ENST00000336803.1
CLDN2
claudin 2
chr8_+_17434689 4.45 ENST00000398074.3
PDGFRL
platelet-derived growth factor receptor-like
chr11_+_114168085 3.85 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr19_+_2977444 3.75 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chrX_+_52511761 3.57 ENST00000399795.3
ENST00000375589.1
XAGE1C
X antigen family, member 1C
chrX_-_52260355 3.55 ENST00000375602.1
ENST00000399800.3
XAGE1A
X antigen family, member 1A
chr17_+_4854375 3.31 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chrX_-_52546189 3.00 ENST00000375570.1
ENST00000429372.2
XAGE1E
X antigen family, member 1E
chrX_-_52533295 3.00 ENST00000375578.1
ENST00000396497.3
XAGE1D
X antigen family, member 1D
chrX_+_52238810 2.84 ENST00000437949.2
ENST00000375616.1
XAGE1B
X antigen family, member 1B
chrX_-_47004878 2.77 ENST00000377811.3
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr17_-_26697304 2.70 ENST00000536498.1
VTN
vitronectin
chr17_+_43299241 2.57 ENST00000328118.3
FMNL1
formin-like 1
chr5_-_58882219 2.28 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_14544099 2.13 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr7_+_134233840 1.83 ENST00000457545.2
AKR1B15
aldo-keto reductase family 1, member B15
chr11_-_65314905 1.79 ENST00000527339.1
LTBP3
latent transforming growth factor beta binding protein 3
chr9_-_139965000 1.78 ENST00000409687.3
SAPCD2
suppressor APC domain containing 2
chr7_-_108097144 1.72 ENST00000418239.1
NRCAM
neuronal cell adhesion molecule
chr11_-_93276582 1.70 ENST00000298966.2
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr5_-_172662303 1.70 ENST00000517440.1
ENST00000329198.4
NKX2-5
NK2 homeobox 5
chr19_+_34887220 1.66 ENST00000592740.1
RP11-618P17.4
Uncharacterized protein
chrX_+_66764375 1.62 ENST00000374690.3
AR
androgen receptor
chr19_+_49622646 1.59 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr6_-_31697977 1.58 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_51308175 1.57 ENST00000345523.4
C19orf48
chromosome 19 open reading frame 48
chr9_-_119162885 1.55 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr12_+_56546363 1.55 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr2_-_42160486 1.53 ENST00000427054.1
AC104654.2
AC104654.2
chr6_-_130031358 1.51 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr12_-_57146095 1.48 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr7_+_69064566 1.46 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr16_-_3074231 1.45 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1 (XPO1 dependent)
chr14_-_50053081 1.38 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr17_+_73089382 1.31 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr2_-_85839146 1.31 ENST00000306336.5
ENST00000409734.3
C2orf68
chromosome 2 open reading frame 68
chr19_-_49622348 1.24 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr1_-_155145721 1.23 ENST00000295682.4
KRTCAP2
keratinocyte associated protein 2
chr12_-_121476959 1.22 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr7_-_16872932 1.19 ENST00000419572.2
ENST00000412973.1
AGR2
anterior gradient 2
chr20_+_277737 1.16 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr12_-_121477039 1.15 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr11_+_72975524 1.09 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_+_16284399 1.07 ENST00000535788.1
UBB
ubiquitin B
chr1_-_25291475 1.07 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr17_-_17480779 1.06 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr17_+_16284104 1.05 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr7_+_72848092 1.04 ENST00000344575.3
FZD9
frizzled family receptor 9
chr12_-_2986107 1.02 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
FOXM1
forkhead box M1
chr9_-_4859260 0.99 ENST00000599351.1
AL158147.2
HCG2011465; Uncharacterized protein
chr7_-_37488834 0.99 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr7_-_76955563 0.99 ENST00000441833.2
GSAP
gamma-secretase activating protein
chr10_+_33271469 0.98 ENST00000414157.1
RP11-462L8.1
RP11-462L8.1
chr5_-_172662230 0.98 ENST00000424406.2
NKX2-5
NK2 homeobox 5
chr3_-_123339343 0.98 ENST00000578202.1
MYLK
myosin light chain kinase
chr5_-_172662197 0.97 ENST00000521848.1
NKX2-5
NK2 homeobox 5
chr2_+_47630108 0.96 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chr9_+_134103496 0.96 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr12_+_56546223 0.94 ENST00000550443.1
ENST00000207437.5
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr19_-_49955050 0.93 ENST00000262265.5
PIH1D1
PIH1 domain containing 1
chr3_+_69134124 0.92 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr18_+_3448455 0.92 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr4_-_40516560 0.87 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr9_-_100000957 0.87 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
RP11-498P14.5
chr9_-_20622478 0.86 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_-_62474803 0.86 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr19_-_51143075 0.85 ENST00000600079.1
ENST00000593901.1
SYT3
synaptotagmin III
chr17_+_33895090 0.84 ENST00000592381.1
RP11-1094M14.11
RP11-1094M14.11
chr8_-_145653885 0.84 ENST00000531032.1
ENST00000292510.4
ENST00000377348.2
ENST00000530790.1
ENST00000533806.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr12_-_51611477 0.84 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr5_-_43515231 0.84 ENST00000306862.2
C5orf34
chromosome 5 open reading frame 34
chr11_+_72975578 0.84 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_46740730 0.83 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr12_-_123717643 0.82 ENST00000541437.1
ENST00000606320.1
MPHOSPH9
M-phase phosphoprotein 9
chr15_-_40401062 0.82 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr11_+_72975559 0.82 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_+_134274354 0.81 ENST00000367869.1
TBPL1
TBP-like 1
chr7_+_140396465 0.81 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr16_-_67224002 0.80 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
EXOC3L1
exocyst complex component 3-like 1
chr6_-_105627735 0.79 ENST00000254765.3
POPDC3
popeye domain containing 3
chrX_-_19533379 0.78 ENST00000338883.4
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr2_-_217560248 0.76 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr6_-_32119877 0.76 ENST00000375152.2
PRRT1
proline-rich transmembrane protein 1
chr17_-_33390667 0.75 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr10_-_69991865 0.74 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr1_+_41157361 0.74 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
NFYC
nuclear transcription factor Y, gamma
chr7_-_139763521 0.73 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr2_+_47630255 0.71 ENST00000406134.1
MSH2
mutS homolog 2
chr15_-_34502278 0.70 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1
katanin p80 subunit B-like 1
chr12_+_100897130 0.70 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr7_-_37488777 0.70 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chr6_-_32119676 0.69 ENST00000211413.5
PRRT1
proline-rich transmembrane protein 1
chr2_-_21022818 0.69 ENST00000440866.2
ENST00000541941.1
ENST00000402479.2
ENST00000435420.2
ENST00000432947.1
ENST00000403006.2
ENST00000419825.2
ENST00000381090.3
ENST00000237822.3
ENST00000412261.1
C2orf43
chromosome 2 open reading frame 43
chr2_-_208489707 0.69 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A
methyltransferase like 21A
chr11_+_64808368 0.68 ENST00000531072.1
ENST00000398846.1
SAC3D1
SAC3 domain containing 1
chr4_+_140586922 0.68 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr2_+_170550944 0.68 ENST00000359744.3
ENST00000438838.1
ENST00000438710.1
ENST00000449906.1
ENST00000498202.2
ENST00000272797.4
PHOSPHO2
KLHL23
phosphatase, orphan 2
kelch-like family member 23
chr10_+_74653330 0.65 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr3_-_123339418 0.65 ENST00000583087.1
MYLK
myosin light chain kinase
chr12_+_123717458 0.64 ENST00000253233.1
C12orf65
chromosome 12 open reading frame 65
chr4_-_141074123 0.64 ENST00000502696.1
MAML3
mastermind-like 3 (Drosophila)
chr19_-_10420459 0.64 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr3_-_9921934 0.64 ENST00000423850.1
CIDEC
cell death-inducing DFFA-like effector c
chr5_+_143584814 0.63 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr12_-_11091862 0.60 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr12_-_118406028 0.59 ENST00000425217.1
KSR2
kinase suppressor of ras 2
chr2_-_136873735 0.57 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr11_-_17410629 0.57 ENST00000526912.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr1_-_201140673 0.57 ENST00000367333.2
TMEM9
transmembrane protein 9
chr4_+_169575875 0.56 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr7_+_26331541 0.56 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr2_+_202937972 0.55 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr11_-_67211263 0.54 ENST00000393893.1
CORO1B
coronin, actin binding protein, 1B
chr7_+_66386204 0.54 ENST00000341567.4
ENST00000607045.1
TMEM248
transmembrane protein 248
chr1_+_15802594 0.54 ENST00000375910.3
CELA2B
chymotrypsin-like elastase family, member 2B
chr2_-_191878162 0.53 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr12_-_123756687 0.52 ENST00000261692.2
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr2_-_208489275 0.51 ENST00000272839.3
ENST00000426075.1
METTL21A
methyltransferase like 21A
chrX_-_49121165 0.51 ENST00000376207.4
ENST00000376199.2
FOXP3
forkhead box P3
chr9_-_123676827 0.51 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr5_-_43515125 0.49 ENST00000509489.1
C5orf34
chromosome 5 open reading frame 34
chr5_-_20575959 0.49 ENST00000507958.1
CDH18
cadherin 18, type 2
chr19_-_49955096 0.49 ENST00000595550.1
PIH1D1
PIH1 domain containing 1
chr3_+_27754397 0.47 ENST00000606069.1
RP11-222K16.2
RP11-222K16.2
chr15_+_63340647 0.47 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr5_-_142783175 0.46 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr19_+_9361606 0.46 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr10_-_70092635 0.45 ENST00000309049.4
PBLD
phenazine biosynthesis-like protein domain containing
chr11_-_65374430 0.45 ENST00000532507.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr2_+_232316906 0.45 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr10_-_70092671 0.44 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr4_+_165675269 0.43 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr6_+_31553978 0.43 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chrX_-_102943022 0.42 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr10_-_14920599 0.42 ENST00000609399.1
RP11-398C13.6
RP11-398C13.6
chr2_-_136875712 0.42 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr15_+_63340553 0.41 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr12_+_110906169 0.41 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr8_-_74205851 0.40 ENST00000396467.1
RPL7
ribosomal protein L7
chr4_+_3465027 0.39 ENST00000389653.2
ENST00000507039.1
ENST00000340083.5
DOK7
docking protein 7
chr9_+_19049372 0.39 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr18_-_60986613 0.39 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr9_-_85882145 0.38 ENST00000328788.1
FRMD3
FERM domain containing 3
chr8_+_145215928 0.38 ENST00000528919.1
MROH1
maestro heat-like repeat family member 1
chrX_-_48827976 0.38 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr3_+_39424828 0.38 ENST00000273158.4
ENST00000431510.1
SLC25A38
solute carrier family 25, member 38
chr8_+_143781883 0.37 ENST00000522591.1
LY6K
lymphocyte antigen 6 complex, locus K
chr2_-_85555385 0.37 ENST00000377386.3
TGOLN2
trans-golgi network protein 2
chr12_+_122181529 0.37 ENST00000541467.1
TMEM120B
transmembrane protein 120B
chr17_+_47448102 0.37 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr19_-_36391434 0.37 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr4_+_14113592 0.36 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chr4_-_171011323 0.36 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
AADAT
aminoadipate aminotransferase
chr7_-_23510086 0.35 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr1_-_72748417 0.34 ENST00000357731.5
NEGR1
neuronal growth regulator 1
chr5_-_142782862 0.34 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_+_31553901 0.33 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1
leukocyte specific transcript 1
chr12_-_13248562 0.33 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr10_+_114135004 0.33 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_-_41116454 0.33 ENST00000427569.2
ENST00000430739.1
AARSD1
alanyl-tRNA synthetase domain containing 1
chr4_+_139694701 0.32 ENST00000502606.1
RP11-98O2.1
RP11-98O2.1
chr6_+_134274322 0.32 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr4_-_176733377 0.32 ENST00000505375.1
GPM6A
glycoprotein M6A
chr9_+_100000717 0.32 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
CCDC180
coiled-coil domain containing 180
chr19_+_24216213 0.31 ENST00000594934.1
ENST00000597683.1
ENST00000342944.6
CTD-2017D11.1
ZNF254
CTD-2017D11.1
zinc finger protein 254
chr20_-_44993012 0.31 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
SLC35C2
solute carrier family 35 (GDP-fucose transporter), member C2
chr4_+_95129061 0.31 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_-_20251744 0.31 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr18_-_60986962 0.31 ENST00000333681.4
BCL2
B-cell CLL/lymphoma 2
chr7_+_26331678 0.30 ENST00000446848.2
SNX10
sorting nexin 10
chr19_+_38779778 0.30 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
SPINT2
CTB-102L5.4
serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4
chr6_-_10694766 0.30 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
C6orf52
chromosome 6 open reading frame 52
chr13_-_25496926 0.30 ENST00000545981.1
ENST00000381884.4
CENPJ
centromere protein J
chr1_-_1677358 0.29 ENST00000355439.2
ENST00000400924.1
ENST00000246421.4
SLC35E2
solute carrier family 35, member E2
chr11_+_20385327 0.29 ENST00000451739.2
ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr8_-_144660771 0.28 ENST00000449291.2
NAPRT1
nicotinate phosphoribosyltransferase domain containing 1
chr14_+_78227105 0.28 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr6_-_113754604 0.28 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr11_+_120107344 0.28 ENST00000260264.4
POU2F3
POU class 2 homeobox 3
chr1_+_15783222 0.28 ENST00000359621.4
CELA2A
chymotrypsin-like elastase family, member 2A
chr13_-_47471155 0.28 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr1_+_15480197 0.28 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
TMEM51
transmembrane protein 51
chr1_+_244816237 0.28 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr11_-_59578202 0.27 ENST00000300151.4
MRPL16
mitochondrial ribosomal protein L16
chr1_+_145524891 0.27 ENST00000369304.3
ITGA10
integrin, alpha 10
chr2_+_99797636 0.27 ENST00000409145.1
MRPL30
mitochondrial ribosomal protein L30
chr16_+_69958887 0.26 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr15_-_72514866 0.26 ENST00000562997.1
PKM
pyruvate kinase, muscle
chr5_-_159766528 0.26 ENST00000505287.2
CCNJL
cyclin J-like
chr2_-_10830093 0.26 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
NOL10
nucleolar protein 10
chr2_+_216176761 0.26 ENST00000540518.1
ENST00000435675.1
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr9_+_92219919 0.25 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr17_-_74049720 0.25 ENST00000602720.1
SRP68
signal recognition particle 68kDa
chr2_+_216176540 0.25 ENST00000236959.9
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr8_+_67344710 0.25 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr19_-_55836669 0.25 ENST00000326652.4
TMEM150B
transmembrane protein 150B
chr1_+_41157421 0.24 ENST00000372654.1
NFYC
nuclear transcription factor Y, gamma
chr1_-_240775447 0.24 ENST00000318160.4
GREM2
gremlin 2, DAN family BMP antagonist
chr12_-_13248705 0.24 ENST00000396310.2
GSG1
germ cell associated 1
chr6_-_32083106 0.24 ENST00000442721.1
TNXB
tenascin XB

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0060929 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.5 1.6 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.4 3.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.4 1.4 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.4 2.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 1.0 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.3 1.7 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.3 0.9 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.3 1.8 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3 0.8 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.3 0.8 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3 2.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.2 1.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 2.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.9 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 0.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 3.9 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2 0.5 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.2 1.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.7 GO:0090293 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 2.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 1.2 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.2 0.5 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2 0.6 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 4.4 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.1 5.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.6 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.5 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.0 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.9 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 1.9 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.3 GO:0015993 molecular hydrogen transport(GO:0015993)
0.1 1.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.2 GO:0043132 NAD transport(GO:0043132)
0.1 1.9 GO:0051014 actin filament severing(GO:0051014)
0.1 0.1 GO:0072209 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
0.1 0.2 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.1 0.2 GO:0071529 cementum mineralization(GO:0071529)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0010513 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 1.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.5 GO:0009607 response to biotic stimulus(GO:0009607)
0.1 1.0 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.4 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.1 3.6 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 0.2 GO:1903947 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 1.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 3.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.8 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.6 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.8 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.3 GO:0061511 centriole elongation(GO:0061511)
0.0 0.4 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 1.2 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 1.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.7 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.8 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 1.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 2.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 1.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.6 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.2 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.6 1.7 GO:0032302 MutSbeta complex(GO:0032302)
0.4 1.6 GO:1990742 microvesicle(GO:1990742)
0.4 3.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 0.8 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.2 1.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.2 3.7 GO:0032059 bleb(GO:0032059)
0.1 2.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 1.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 0.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.3 GO:0036457 keratohyalin granule(GO:0036457)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.6 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.0 3.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 1.0 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 2.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 5.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
1.0 3.9 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.7 3.6 GO:0010736 serum response element binding(GO:0010736)
0.6 1.7 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.4 1.5 GO:0003896 DNA primase activity(GO:0003896)
0.4 3.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 2.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.4 1.1 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.3 2.7 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.3 1.6 GO:0004882 androgen receptor activity(GO:0004882)
0.2 0.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 1.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 2.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 0.7 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 1.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.1 2.6 GO:0005522 profilin binding(GO:0005522)
0.1 1.8 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 2.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 2.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.7 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 1.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0043199 sulfate binding(GO:0043199)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 8.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 2.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 5.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 5.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.7 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 3.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling