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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PBX1

Z-value: 0.68

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
ENSG00000185630.14 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164528866_1645288770.742.0e-04Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_238108575 2.21 ENST00000604646.1
MT-RNR2-like 11 (pseudogene)
chr7_-_27142290 2.03 ENST00000222718.5
homeobox A2
chr12_+_20968608 1.74 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr22_+_29138013 1.38 ENST00000216027.3
ENST00000398941.2
HscB mitochondrial iron-sulfur cluster co-chaperone
chr6_-_26032288 1.32 ENST00000244661.2
histone cluster 1, H3b
chr11_+_114166536 1.32 ENST00000299964.3
nicotinamide N-methyltransferase
chr12_+_21679220 1.29 ENST00000256969.2
chromosome 12 open reading frame 39
chr12_+_54402790 1.22 ENST00000040584.4
homeobox C8
chr16_+_15596123 1.17 ENST00000452191.2
chromosome 16 open reading frame 45
chr6_+_151561085 1.13 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr17_+_4853442 1.13 ENST00000522301.1
enolase 3 (beta, muscle)
chr17_+_43239231 1.12 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
hexamethylene bis-acetamide inducible 2
chr7_-_107883678 1.05 ENST00000417701.1
neuronal cell adhesion molecule
chr15_-_64673630 1.05 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr11_-_126870655 1.05 ENST00000525144.2
kin of IRRE like 3 (Drosophila)
chr16_+_69458537 1.03 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
cytochrome b5 type B (outer mitochondrial membrane)
chr15_-_64673665 1.03 ENST00000300035.4
KIAA0101
chr17_-_38821373 1.02 ENST00000394052.3
keratin 222
chr18_+_44526786 0.94 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chrX_-_1331527 0.92 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
cytokine receptor-like factor 2
chr6_-_27775694 0.92 ENST00000377401.2
histone cluster 1, H2bl
chr11_+_64794991 0.92 ENST00000352068.5
ENST00000525648.1
sorting nexin 15
chr12_+_79258444 0.92 ENST00000261205.4
synaptotagmin I
chr11_-_126870683 0.91 ENST00000525704.2
kin of IRRE like 3 (Drosophila)
chr6_+_27114861 0.89 ENST00000377459.1
histone cluster 1, H2ah
chr6_+_151561506 0.88 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr14_+_50065459 0.86 ENST00000318317.4
leucine rich repeat protein 1
chr12_+_41136144 0.85 ENST00000548005.1
ENST00000552248.1
contactin 1
chr11_-_104035088 0.84 ENST00000302251.5
platelet derived growth factor D
chr15_-_54025300 0.84 ENST00000559418.1
WD repeat domain 72
chr20_+_44441271 0.81 ENST00000335046.3
ENST00000243893.6
ubiquitin-conjugating enzyme E2C
chr9_-_32573130 0.80 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr20_+_48909240 0.80 ENST00000371639.3
RP11-290F20.1
chr17_-_26695013 0.80 ENST00000555059.2
Homeobox protein SEBOX
chr17_+_8191815 0.79 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr12_+_12870055 0.79 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr17_-_26941179 0.79 ENST00000301037.5
ENST00000530121.1
ENST00000525510.1
ENST00000577790.1
ENST00000531839.1
ENST00000534850.1
uncharacterized serine/threonine-protein kinase SgK494
Uncharacterized protein
chr17_-_26694979 0.77 ENST00000438614.1
vitronectin
chr14_-_64971893 0.76 ENST00000555220.1
zinc finger and BTB domain containing 25
chr4_-_6557336 0.76 ENST00000507294.1
protein phosphatase 2, regulatory subunit B, gamma
chr2_-_242626127 0.75 ENST00000445261.1
deoxythymidylate kinase (thymidylate kinase)
chr11_-_34938039 0.75 ENST00000395787.3
APAF1 interacting protein
chr12_+_21654714 0.73 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
golgi transport 1B
chr7_-_7680601 0.72 ENST00000396682.2
replication protein A3, 14kDa
chrX_+_92929192 0.70 ENST00000332647.4
family with sequence similarity 133, member A
chr6_+_27775899 0.70 ENST00000358739.3
histone cluster 1, H2ai
chr12_+_79258547 0.70 ENST00000457153.2
synaptotagmin I
chr14_+_23938891 0.69 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
neuroguidin, EIF4E binding protein
chr7_-_47520869 0.68 ENST00000415929.1
tensin 3
chr5_+_162864575 0.68 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr8_+_99076509 0.67 ENST00000318528.3
chromosome 8 open reading frame 47
chr5_-_59481406 0.66 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr18_+_44526744 0.66 ENST00000585469.1
katanin p60 subunit A-like 2
chr10_+_5238793 0.65 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr11_-_34937858 0.64 ENST00000278359.5
APAF1 interacting protein
chr12_-_76478686 0.63 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr14_+_50065376 0.61 ENST00000298288.6
leucine rich repeat protein 1
chr11_-_31531121 0.60 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr2_+_44396000 0.59 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr19_-_49121054 0.58 ENST00000546623.1
ENST00000084795.5
ribosomal protein L18
chr19_+_782755 0.57 ENST00000606242.1
ENST00000586061.1
AC006273.5
chr3_-_150264272 0.57 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
stress-associated endoplasmic reticulum protein 1
chr2_+_20646824 0.57 ENST00000272233.4
ras homolog family member B
chr8_-_95487331 0.55 ENST00000336148.5
RAD54 homolog B (S. cerevisiae)
chr8_+_98788003 0.54 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chrX_-_70474499 0.53 ENST00000353904.2
zinc finger, MYM-type 3
chr6_-_26250835 0.52 ENST00000446824.2
histone cluster 1, H3f
chrX_-_10645724 0.51 ENST00000413894.1
midline 1 (Opitz/BBB syndrome)
chr7_+_77325738 0.51 ENST00000334955.8
round spermatid basic protein 1-like
chr12_+_21168630 0.50 ENST00000421593.2
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr11_-_118966167 0.50 ENST00000530167.1
H2A histone family, member X
chr21_+_27543175 0.49 ENST00000608591.1
ENST00000609365.1
AP000230.1
chr16_+_19222479 0.49 ENST00000568433.1
synaptotagmin XVII
chr11_+_844406 0.48 ENST00000397404.1
tetraspanin 4
chr3_-_4927447 0.46 ENST00000449914.1
Uncharacterized protein
chr22_-_30642728 0.45 ENST00000403987.3
leukemia inhibitory factor
chr19_-_49955050 0.45 ENST00000262265.5
PIH1 domain containing 1
chr2_-_190044480 0.44 ENST00000374866.3
collagen, type V, alpha 2
chr11_-_32816156 0.43 ENST00000531481.1
ENST00000335185.5
coiled-coil domain containing 73
chr3_+_159557637 0.43 ENST00000445224.2
schwannomin interacting protein 1
chr9_-_88356789 0.43 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
ATP/GTP binding protein 1
chr14_+_50234309 0.43 ENST00000298307.5
kelch domain containing 2
chr2_+_62132800 0.42 ENST00000538736.1
copper metabolism (Murr1) domain containing 1
chr1_-_54405773 0.42 ENST00000371376.1
heat shock protein family B (small), member 11
chr17_-_27038063 0.42 ENST00000439862.3
protein interacting with cyclin A1
chr22_-_30642782 0.42 ENST00000249075.3
leukemia inhibitory factor
chr8_-_108510224 0.41 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr5_+_68513622 0.41 ENST00000512880.1
ENST00000602380.1
mitochondrial ribosomal protein S36
chrX_-_70473957 0.39 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
zinc finger, MYM-type 3
chr2_-_200322723 0.39 ENST00000417098.1
SATB homeobox 2
chr3_+_129159039 0.39 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
intraflagellar transport 122 homolog (Chlamydomonas)
chr17_+_43239191 0.38 ENST00000589230.1
hexamethylene bis-acetamide inducible 2
chrX_-_70474377 0.38 ENST00000373978.1
ENST00000373981.1
zinc finger, MYM-type 3
chr10_+_124320156 0.38 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr16_+_50059182 0.38 ENST00000562576.1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr8_+_98788057 0.38 ENST00000517924.1
lysosomal protein transmembrane 4 beta
chr8_-_95487272 0.37 ENST00000297592.5
RAD54 homolog B (S. cerevisiae)
chr19_-_11266471 0.37 ENST00000592540.1
SPC24, NDC80 kinetochore complex component
chrX_+_140084756 0.37 ENST00000449283.1
SPANX family, member B2
chr15_-_37393406 0.37 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr11_+_31531291 0.36 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr4_-_111536534 0.35 ENST00000503456.1
ENST00000513690.1
RP11-380D23.2
chr12_-_54653313 0.35 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chrX_+_119737806 0.35 ENST00000371317.5
malignant T cell amplified sequence 1
chr14_-_104181771 0.35 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
X-ray repair complementing defective repair in Chinese hamster cells 3
chr19_-_51141196 0.34 ENST00000338916.4
synaptotagmin III
chr9_-_123676827 0.34 ENST00000546084.1
TNF receptor-associated factor 1
chr19_-_11266437 0.34 ENST00000586708.1
ENST00000591396.1
ENST00000592967.1
ENST00000585486.1
ENST00000585567.1
SPC24, NDC80 kinetochore complex component
chr18_-_56985873 0.33 ENST00000299721.3
complexin 4
chr4_-_105416039 0.33 ENST00000394767.2
CXXC finger protein 4
chr11_+_47279155 0.33 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
nuclear receptor subfamily 1, group H, member 3
chr10_+_69869237 0.32 ENST00000373675.3
myopalladin
chr16_-_70323422 0.31 ENST00000261772.8
alanyl-tRNA synthetase
chr5_+_140207536 0.31 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr19_-_5903714 0.31 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr17_+_58755184 0.31 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr3_+_129158926 0.31 ENST00000347300.2
ENST00000296266.3
intraflagellar transport 122 homolog (Chlamydomonas)
chr22_-_29137771 0.31 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
checkpoint kinase 2
chr17_+_58018269 0.31 ENST00000591035.1
Uncharacterized protein
chr9_+_140135665 0.31 ENST00000340384.4
tubulin, beta 4B class IVb
chr7_+_7196565 0.30 ENST00000429911.1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr16_+_50059125 0.30 ENST00000427478.2
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr9_+_106856831 0.29 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr10_+_124320195 0.29 ENST00000359586.6
deleted in malignant brain tumors 1
chr10_+_63422695 0.29 ENST00000330194.2
ENST00000389639.3
chromosome 10 open reading frame 107
chrX_-_110655306 0.29 ENST00000371993.2
doublecortin
chrX_+_120181457 0.29 ENST00000328078.1
glutamate dehydrogenase 2
chrX_+_95939711 0.28 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr10_+_60028818 0.28 ENST00000333926.5
CDGSH iron sulfur domain 1
chr19_+_35417939 0.27 ENST00000601142.1
ENST00000426813.2
zinc finger protein 30
chr10_+_48189612 0.27 ENST00000453919.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr7_-_7782204 0.27 ENST00000418534.2
AC007161.5
chr16_+_53483983 0.27 ENST00000544545.1
retinoblastoma-like 2 (p130)
chrX_-_102757802 0.27 ENST00000372633.1
RAB40A, member RAS oncogene family
chr21_-_16125773 0.27 ENST00000454128.2
AF127936.3
chr9_-_131486367 0.27 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
zinc finger, DHHC-type containing 12
chr19_-_16008880 0.27 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr10_+_69865866 0.27 ENST00000354393.2
myopalladin
chr15_+_36871983 0.27 ENST00000437989.2
ENST00000569302.1
chromosome 15 open reading frame 41
chr5_+_140213815 0.26 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chr1_-_98511756 0.26 ENST00000602984.1
ENST00000602852.1
MIR137 host gene (non-protein coding)
chr5_-_94417186 0.26 ENST00000312216.8
ENST00000512425.1
multiple C2 domains, transmembrane 1
chr19_+_33072373 0.26 ENST00000586035.1
programmed cell death 5
chr2_+_201997492 0.26 ENST00000494258.1
CASP8 and FADD-like apoptosis regulator
chr18_+_29171689 0.26 ENST00000237014.3
transthyretin
chr12_-_106477805 0.26 ENST00000553094.1
ENST00000549704.1
NUAK family, SNF1-like kinase, 1
chr19_-_33360647 0.25 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr2_-_200323414 0.25 ENST00000443023.1
SATB homeobox 2
chr10_-_101190202 0.25 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr5_-_94417314 0.25 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr5_-_94417339 0.25 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
multiple C2 domains, transmembrane 1
chr1_+_156589051 0.25 ENST00000255039.1
hyaluronan and proteoglycan link protein 2
chr17_-_15519008 0.25 ENST00000261644.8
CMT1A duplicated region transcript 1
chr2_-_96971232 0.24 ENST00000323853.5
small nuclear ribonucleoprotein 200kDa (U5)
chr14_+_88851874 0.24 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
spermatogenesis associated 7
chr10_-_31288398 0.24 ENST00000538351.2
zinc finger protein 438
chr6_-_110736742 0.24 ENST00000368924.3
ENST00000368923.3
D-aspartate oxidase
chr2_-_27886460 0.24 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
suppressor of Ty 7 (S. cerevisiae)-like
chr9_-_73736511 0.23 ENST00000377110.3
ENST00000377111.2
transient receptor potential cation channel, subfamily M, member 3
chr7_-_77325545 0.23 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L antisense RNA 1
chr19_+_46498704 0.23 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
coiled-coil domain containing 61
chr8_+_99076750 0.23 ENST00000545282.1
chromosome 8 open reading frame 47
chr3_-_178103144 0.23 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
chr1_+_226250379 0.23 ENST00000366815.3
ENST00000366814.3
H3 histone, family 3A
chr12_-_122985067 0.23 ENST00000540586.1
ENST00000543897.1
zinc finger, CCHC domain containing 8
chr18_-_56985776 0.22 ENST00000587244.1
complexin 4
chr12_+_101988774 0.22 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr2_-_10587897 0.22 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr2_-_27886676 0.22 ENST00000337768.5
suppressor of Ty 7 (S. cerevisiae)-like
chr4_-_140005341 0.22 ENST00000379549.2
ENST00000512627.1
E74-like factor 2 (ets domain transcription factor)
chr19_-_49955096 0.22 ENST00000595550.1
PIH1 domain containing 1
chrX_+_140677562 0.22 ENST00000370518.3
SPANX family, member A2
chr3_+_150264555 0.22 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
eukaryotic translation initiation factor 2A, 65kDa
chr4_-_140005443 0.21 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
E74-like factor 2 (ets domain transcription factor)
chr16_-_69788816 0.21 ENST00000268802.5
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr11_+_95523621 0.20 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr12_+_56401268 0.20 ENST00000262032.5
IKAROS family zinc finger 4 (Eos)
chr2_+_264869 0.20 ENST00000272067.6
ENST00000272065.5
ENST00000407983.3
acid phosphatase 1, soluble
chr16_+_19078911 0.20 ENST00000321998.5
coenzyme Q7 homolog, ubiquinone (yeast)
chr2_+_264913 0.19 ENST00000439645.2
ENST00000405233.1
acid phosphatase 1, soluble
chr8_-_11996586 0.19 ENST00000333796.3
ubiquitin specific peptidase 17-like family member 2
chr1_+_179262905 0.19 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
sterol O-acyltransferase 1
chr15_-_72521017 0.19 ENST00000561609.1
pyruvate kinase, muscle
chrX_+_95939638 0.19 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
diaphanous-related formin 2
chr12_+_21525818 0.19 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr12_-_91573249 0.19 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr3_-_187388173 0.18 ENST00000287641.3
somatostatin
chr12_-_96389702 0.18 ENST00000552509.1
histidine ammonia-lyase
chr12_-_121342170 0.18 ENST00000353487.2
signal peptide peptidase like 3
chr5_-_86708670 0.18 ENST00000504878.1
cyclin H
chr12_+_101988627 0.18 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr4_+_120056939 0.18 ENST00000307128.5
myozenin 2
chr3_-_129158850 0.18 ENST00000503197.1
ENST00000249910.1
ENST00000429544.2
ENST00000507208.1
methyl-CpG binding domain protein 4
chr15_+_96904487 0.18 ENST00000600790.1
Uncharacterized protein
chr10_+_18689637 0.17 ENST00000377315.4
calcium channel, voltage-dependent, beta 2 subunit
chr4_-_184241927 0.17 ENST00000323319.5
claudin 22
chr11_+_22689648 0.17 ENST00000278187.3
growth arrest-specific 2
chr3_-_46786245 0.17 ENST00000442359.2
protease, serine, 45
chr11_-_74800799 0.16 ENST00000305159.3
olfactory receptor, family 2, subfamily AT, member 4
chr12_+_48722763 0.16 ENST00000335017.1
H1 histone family, member N, testis-specific

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.7 2.0 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.3 0.8 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.3 1.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.8 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.2 1.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.7 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.2 2.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.7 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 1.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.3 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.3 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.8 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.1 0.7 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.6 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.8 GO:1902746 autophagic cell death(GO:0048102) regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.2 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 1.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 2.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014)
0.0 0.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.0 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 1.5 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.7 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 1.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0071400 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.7 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.4 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.8 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 1.6 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.3 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.7 GO:0097255 R2TP complex(GO:0097255)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 1.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.3 0.9 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 0.7 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 1.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 2.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.3 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.7 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 2.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.3 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.2 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.1 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 1.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.0 GO:0020037 heme binding(GO:0020037)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events