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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PDX1

Z-value: 0.54

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Transcription factors associated with PDX1

Gene Symbol Gene ID Gene Info
PDX1
ENSG00000139515.5 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PDX1hg19_v2_chr13_+_28494130_284941680.009.9e-01Click!

Activity profile of PDX1 motif

Sorted Z-values of PDX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_155533787 1.62 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr8_+_32579271 1.47 ENST00000518084.1
NRG1
neuregulin 1
chr3_+_149191723 1.36 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr8_+_32579341 1.32 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr12_+_47610315 1.30 ENST00000548348.1
ENST00000549500.1
PCED1B
PC-esterase domain containing 1B
chr8_+_32579321 1.15 ENST00000522402.1
NRG1
neuregulin 1
chr17_-_46690839 1.15 ENST00000498634.2
HOXB8
homeobox B8
chr1_+_199996702 1.03 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr5_+_174151536 0.95 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr20_+_43029911 0.93 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chrX_-_106243451 0.93 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr11_-_115375107 0.93 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr20_-_50419055 0.93 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr14_-_54423529 0.91 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr15_+_59910132 0.91 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr4_-_139163491 0.91 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chrX_-_106243294 0.89 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr7_-_73038867 0.87 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL
MLX interacting protein-like
chr8_-_37457350 0.85 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chr11_-_31531121 0.85 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr17_+_72427477 0.79 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr15_+_62853562 0.79 ENST00000561311.1
TLN2
talin 2
chr20_+_42984330 0.79 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr7_-_73038822 0.75 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL
MLX interacting protein-like
chr14_+_74034310 0.73 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr7_+_6655225 0.70 ENST00000457543.3
ZNF853
zinc finger protein 853
chr13_-_67802549 0.67 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr16_-_29910853 0.64 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr7_-_33102338 0.64 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr7_-_33102399 0.62 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr1_-_21625486 0.62 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr15_+_80351910 0.62 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr9_-_123639445 0.61 ENST00000312189.6
PHF19
PHD finger protein 19
chr9_-_123639304 0.60 ENST00000436309.1
PHF19
PHD finger protein 19
chrX_+_10031499 0.60 ENST00000454666.1
WWC3
WWC family member 3
chr11_-_8285405 0.59 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr1_-_159832438 0.58 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr1_+_66796401 0.58 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr20_+_60174827 0.57 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr1_+_198608146 0.54 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chrX_-_20236970 0.49 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr17_-_33446735 0.49 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr11_-_8290263 0.48 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr14_-_95236551 0.48 ENST00000238558.3
GSC
goosecoid homeobox
chr20_-_50418972 0.48 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr2_-_145277569 0.48 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr3_-_98235962 0.46 ENST00000513873.1
CLDND1
claudin domain containing 1
chr20_-_271304 0.46 ENST00000400269.3
ENST00000360321.2
C20orf96
chromosome 20 open reading frame 96
chr7_-_99716952 0.45 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr20_-_50418947 0.45 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr15_-_55562582 0.44 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr18_+_3447572 0.44 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr17_+_43238438 0.43 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chrX_+_72783026 0.43 ENST00000373504.6
ENST00000373502.5
CHIC1
cysteine-rich hydrophobic domain 1
chr13_+_78315466 0.43 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr4_+_129732419 0.42 ENST00000510308.1
PHF17
jade family PHD finger 1
chr11_-_124981475 0.41 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chr7_+_116660246 0.41 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr9_-_123639600 0.40 ENST00000373896.3
PHF19
PHD finger protein 19
chr2_+_87769459 0.40 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr7_-_99716940 0.39 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr15_-_72563585 0.39 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr2_+_45168875 0.39 ENST00000260653.3
SIX3
SIX homeobox 3
chr2_+_66918558 0.39 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr9_-_16728161 0.37 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr19_-_56110859 0.37 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr15_+_63188009 0.37 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr20_-_31124186 0.36 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr7_-_99717463 0.36 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_-_51611477 0.35 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chrX_-_46187069 0.35 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr8_-_1922789 0.34 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr13_-_28545276 0.34 ENST00000381020.7
CDX2
caudal type homeobox 2
chr6_+_126221034 0.34 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr8_+_77593448 0.33 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr12_+_107712173 0.33 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr15_+_80351977 0.32 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr6_-_31107127 0.32 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr15_+_75080883 0.32 ENST00000567571.1
CSK
c-src tyrosine kinase
chr16_-_30457048 0.31 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr3_-_131756559 0.31 ENST00000505957.1
CPNE4
copine IV
chr8_+_9953214 0.31 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chrX_+_10126488 0.30 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr9_+_131037623 0.30 ENST00000495313.1
ENST00000372898.2
SWI5
SWI5 recombination repair homolog (yeast)
chr7_+_129015671 0.30 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chrX_-_110655306 0.30 ENST00000371993.2
DCX
doublecortin
chrX_+_133930798 0.29 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr7_-_14029283 0.29 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr10_-_21806759 0.29 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr5_+_156712372 0.28 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr8_+_9953061 0.28 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr12_-_56321397 0.28 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr21_+_30672433 0.28 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_+_43990576 0.28 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr19_+_50016610 0.27 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chrX_-_100129128 0.27 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr8_+_22424551 0.26 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr15_-_55563072 0.26 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr1_+_62439037 0.26 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr1_-_190446759 0.26 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr6_-_116833500 0.26 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr17_-_71223839 0.26 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr4_+_105828537 0.25 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr5_+_135394840 0.25 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chrX_-_106146547 0.25 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr12_-_86650045 0.25 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr13_-_31191642 0.25 ENST00000405805.1
HMGB1
high mobility group box 1
chr4_+_119809984 0.25 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr6_-_33160231 0.24 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr19_-_56135928 0.24 ENST00000591479.1
ENST00000325351.4
ZNF784
zinc finger protein 784
chr6_+_13272904 0.24 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr13_+_78315528 0.24 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr17_+_73452545 0.24 ENST00000314256.7
KIAA0195
KIAA0195
chr7_-_99716914 0.23 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr17_-_27418537 0.23 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr7_+_99717230 0.23 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr14_+_39944025 0.22 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr20_+_62795827 0.22 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr7_+_100860949 0.22 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr22_-_28490123 0.22 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chrX_-_20237059 0.22 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr18_+_32558208 0.22 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr17_+_73539339 0.22 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr15_-_55562479 0.21 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr1_-_212965104 0.21 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1
NSL1, MIS12 kinetochore complex component
chr9_-_136933134 0.21 ENST00000303407.7
BRD3
bromodomain containing 3
chr3_-_167191814 0.21 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr15_-_37393406 0.20 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr17_-_57229155 0.20 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr15_-_65903407 0.20 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9
von Willebrand factor A domain containing 9
chr17_-_40337470 0.20 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr17_-_38911580 0.19 ENST00000312150.4
KRT25
keratin 25
chr18_-_44181442 0.19 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr17_-_27467418 0.19 ENST00000528564.1
MYO18A
myosin XVIIIA
chr2_-_61697862 0.19 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr11_+_130318869 0.19 ENST00000299164.2
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr12_+_49621658 0.19 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr4_-_70518941 0.19 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr9_-_28670283 0.19 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr2_-_166930131 0.19 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr20_+_43538756 0.18 ENST00000537323.1
ENST00000217073.2
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr14_+_100485712 0.18 ENST00000544450.2
EVL
Enah/Vasp-like
chr2_-_190927447 0.18 ENST00000260950.4
MSTN
myostatin
chr12_-_16761007 0.18 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr11_-_85430163 0.18 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr17_-_4458616 0.17 ENST00000381556.2
MYBBP1A
MYB binding protein (P160) 1a
chr17_-_2117600 0.17 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr15_+_28624878 0.17 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr1_-_201140673 0.17 ENST00000367333.2
TMEM9
transmembrane protein 9
chrX_-_133931164 0.17 ENST00000370790.1
ENST00000298090.6
FAM122B
family with sequence similarity 122B
chr18_+_32558380 0.17 ENST00000588349.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr7_-_111424506 0.17 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr3_+_35722424 0.17 ENST00000396481.2
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr17_-_38928414 0.17 ENST00000335552.4
KRT26
keratin 26
chr15_-_65407524 0.17 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr11_+_4510109 0.16 ENST00000307632.3
OR52K1
olfactory receptor, family 52, subfamily K, member 1
chr4_-_138453606 0.16 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr12_+_41831485 0.16 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr14_-_92247032 0.16 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr5_-_96478466 0.15 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr12_-_56106060 0.15 ENST00000452168.2
ITGA7
integrin, alpha 7
chr7_-_111424462 0.15 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chrX_-_18690210 0.15 ENST00000379984.3
RS1
retinoschisin 1
chr4_+_119810134 0.15 ENST00000434046.2
SYNPO2
synaptopodin 2
chrX_-_19817869 0.15 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr17_-_77924627 0.14 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr8_-_131399110 0.14 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr1_-_219615984 0.14 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr1_+_12834984 0.14 ENST00000357726.4
PRAMEF12
PRAME family member 12
chr12_-_86650077 0.14 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr10_-_21186144 0.14 ENST00000377119.1
NEBL
nebulette
chr3_+_115342349 0.14 ENST00000393780.3
GAP43
growth associated protein 43
chr3_+_35722487 0.14 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr4_-_89978299 0.14 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A
family with sequence similarity 13, member A
chr9_-_117267717 0.14 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chrX_-_130423200 0.14 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr2_-_227050079 0.13 ENST00000423838.1
AC068138.1
AC068138.1
chr7_-_151217001 0.13 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr2_+_96331830 0.13 ENST00000425887.2
AC008268.1
AC008268.1
chr15_+_67841330 0.13 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chrX_-_21676442 0.13 ENST00000379499.2
KLHL34
kelch-like family member 34
chr20_-_56286479 0.13 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_+_92261516 0.13 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr3_-_39321512 0.13 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr11_-_85430204 0.13 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr5_-_142780280 0.12 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_+_108541608 0.12 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr4_-_66536057 0.12 ENST00000273854.3
EPHA5
EPH receptor A5
chr11_-_85430088 0.12 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr21_+_17442799 0.12 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr4_+_105828492 0.12 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr12_-_32908809 0.12 ENST00000324868.8
YARS2
tyrosyl-tRNA synthetase 2, mitochondrial
chr12_-_16762971 0.12 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_77593474 0.11 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr5_+_60933634 0.11 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr12_-_53171128 0.11 ENST00000332411.2
KRT76
keratin 76
chr19_+_36632204 0.11 ENST00000592354.1
CAPNS1
calpain, small subunit 1
chr17_-_39150385 0.11 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr10_-_27529486 0.11 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr8_-_42234745 0.11 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of PDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.4 1.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.3 0.9 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 0.9 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 0.9 GO:2000007 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.6 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.3 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 1.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.6 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.5 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701) bone marrow development(GO:0048539)
0.1 1.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.5 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.6 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.6 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 1.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.6 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.3 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.9 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.4 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 1.4 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 3.9 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 1.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.9 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 0.9 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.3 1.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 0.9 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.3 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 1.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.6 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.9 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation