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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PGR

Z-value: 0.51

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Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
PGR
ENSG00000082175.10 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PGRhg19_v2_chr11_-_100999775_100999801-0.331.6e-01Click!

Activity profile of PGR motif

Sorted Z-values of PGR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_32908792 0.71 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_+_209859510 0.71 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr12_+_56473628 0.67 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr13_+_102104952 0.59 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr7_-_37026108 0.57 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr3_-_114035026 0.57 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr2_-_25451065 0.56 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr17_-_26694979 0.53 ENST00000438614.1
VTN
vitronectin
chr14_+_24641062 0.52 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8
REC8 meiotic recombination protein
chr7_-_127671674 0.52 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr2_-_27531313 0.51 ENST00000296099.2
UCN
urocortin
chr18_+_61445007 0.51 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr7_+_22766766 0.49 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr6_-_43276535 0.48 ENST00000372569.3
ENST00000274990.4
CRIP3
cysteine-rich protein 3
chrX_+_99899180 0.48 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr17_-_26697304 0.45 ENST00000536498.1
VTN
vitronectin
chr7_-_127672146 0.45 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr4_-_23735183 0.44 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr19_+_49377575 0.42 ENST00000600406.1
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr13_+_102104980 0.42 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_-_49722523 0.41 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_-_32908765 0.41 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr16_+_50582222 0.41 ENST00000268459.3
NKD1
naked cuticle homolog 1 (Drosophila)
chr11_-_615570 0.40 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr12_-_70093235 0.39 ENST00000266661.4
BEST3
bestrophin 3
chr17_+_25958174 0.39 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr19_-_9003586 0.38 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr1_+_1846519 0.38 ENST00000378604.3
CALML6
calmodulin-like 6
chr17_-_26903900 0.36 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr1_+_12524965 0.35 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr17_+_46970127 0.35 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr7_-_150946015 0.35 ENST00000262188.8
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr12_-_53901266 0.35 ENST00000609999.1
ENST00000267017.3
NPFF
neuropeptide FF-amide peptide precursor
chr17_+_39846114 0.32 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr20_-_25207370 0.31 ENST00000593352.1
AL035252.1
HCG2018895; Uncharacterized protein
chr3_-_114343768 0.31 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr19_-_42947121 0.30 ENST00000601181.1
CXCL17
chemokine (C-X-C motif) ligand 17
chr12_-_71551652 0.30 ENST00000546561.1
TSPAN8
tetraspanin 8
chr5_-_121413974 0.29 ENST00000231004.4
LOX
lysyl oxidase
chr17_+_46970134 0.29 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_+_51153045 0.29 ENST00000458538.1
C19orf81
chromosome 19 open reading frame 81
chr17_+_46970178 0.29 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_-_8642289 0.29 ENST00000596675.1
ENST00000338257.8
MYO1F
myosin IF
chr6_-_89927151 0.28 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chrX_+_70443050 0.27 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr3_-_52001448 0.27 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr5_+_102201430 0.27 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chrX_+_70364667 0.26 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr6_-_75915757 0.26 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr8_-_116681686 0.26 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr8_+_9953214 0.26 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr9_-_131940526 0.26 ENST00000372491.2
IER5L
immediate early response 5-like
chr5_+_180650271 0.25 ENST00000351937.5
ENST00000315073.5
TRIM41
tripartite motif containing 41
chr8_+_35649365 0.25 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr2_+_27193480 0.25 ENST00000233121.2
ENST00000405074.3
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr5_+_102201509 0.24 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr11_+_35222629 0.24 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chrX_+_54834004 0.24 ENST00000375068.1
MAGED2
melanoma antigen family D, 2
chr2_+_105050794 0.23 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr4_+_79567314 0.23 ENST00000503539.1
ENST00000504675.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr19_-_40440533 0.23 ENST00000221347.6
FCGBP
Fc fragment of IgG binding protein
chr1_+_202183200 0.23 ENST00000439764.2
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr16_-_66952779 0.23 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr19_+_13135790 0.22 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_-_66952742 0.22 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr1_+_41174988 0.22 ENST00000372652.1
NFYC
nuclear transcription factor Y, gamma
chr12_-_53575120 0.22 ENST00000542115.1
CSAD
cysteine sulfinic acid decarboxylase
chr18_+_21529811 0.21 ENST00000588004.1
LAMA3
laminin, alpha 3
chr18_+_29171689 0.21 ENST00000237014.3
TTR
transthyretin
chr7_+_99202003 0.21 ENST00000609449.1
GS1-259H13.2
GS1-259H13.2
chr3_+_49057876 0.21 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr6_-_32157947 0.21 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr3_+_111260856 0.21 ENST00000352690.4
CD96
CD96 molecule
chr2_-_158182105 0.20 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr11_+_64851729 0.20 ENST00000526791.1
ENST00000526945.1
ZFPL1
zinc finger protein-like 1
chr6_-_150212029 0.20 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
RAET1E
retinoic acid early transcript 1E
chr6_+_30951487 0.20 ENST00000486149.2
ENST00000376296.3
MUC21
mucin 21, cell surface associated
chr8_+_145065705 0.19 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr17_+_11144580 0.19 ENST00000441885.3
ENST00000432116.3
ENST00000409168.3
SHISA6
shisa family member 6
chr15_+_54305101 0.19 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C
unc-13 homolog C (C. elegans)
chr2_-_216300784 0.19 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr7_+_73442422 0.19 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN
elastin
chr10_+_63808970 0.19 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr7_+_73442487 0.19 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr1_-_145715565 0.18 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr10_+_104178946 0.18 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr4_+_57276661 0.18 ENST00000598320.1
AC068620.1
Uncharacterized protein
chr4_+_117220016 0.18 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr11_-_10530723 0.18 ENST00000536684.1
MTRNR2L8
MT-RNR2-like 8
chr5_+_102201722 0.18 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr19_+_41119323 0.18 ENST00000599724.1
ENST00000597071.1
ENST00000243562.9
LTBP4
latent transforming growth factor beta binding protein 4
chr2_-_158182322 0.18 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr11_-_75379612 0.18 ENST00000526740.1
MAP6
microtubule-associated protein 6
chr5_-_138718973 0.18 ENST00000353963.3
ENST00000348729.3
SLC23A1
solute carrier family 23 (ascorbic acid transporter), member 1
chr17_-_7760457 0.18 ENST00000576384.1
LSMD1
LSM domain containing 1
chr13_+_32838801 0.17 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr14_+_29299437 0.17 ENST00000550827.1
ENST00000548087.1
ENST00000551588.1
ENST00000550122.1
CTD-2384A14.1
CTD-2384A14.1
chr4_+_177241094 0.17 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr6_-_30080876 0.17 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr10_-_28571015 0.17 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr18_+_6729698 0.17 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr5_-_95018660 0.17 ENST00000395899.3
ENST00000274432.8
SPATA9
spermatogenesis associated 9
chr15_+_42651691 0.17 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
CAPN3
calpain 3, (p94)
chr17_-_7760779 0.17 ENST00000335155.5
ENST00000575071.1
LSMD1
LSM domain containing 1
chr4_-_90759440 0.17 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_155146318 0.17 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr2_-_220034745 0.17 ENST00000455516.2
ENST00000396775.3
ENST00000295738.7
SLC23A3
solute carrier family 23, member 3
chr4_-_71532339 0.17 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_+_66124590 0.17 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr11_+_64851666 0.16 ENST00000525509.1
ENST00000294258.3
ENST00000526334.1
ZFPL1
zinc finger protein-like 1
chr2_+_113885138 0.16 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr17_+_22022437 0.16 ENST00000540040.1
MTRNR2L1
MT-RNR2-like 1
chr1_+_155583012 0.16 ENST00000462250.2
MSTO1
misato 1, mitochondrial distribution and morphology regulator
chrX_+_54834159 0.16 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2
melanoma antigen family D, 2
chr4_-_71532207 0.16 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chrX_-_21776281 0.16 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr10_+_90562705 0.16 ENST00000539337.1
LIPM
lipase, family member M
chr10_-_49482907 0.16 ENST00000374201.3
ENST00000407470.4
FRMPD2
FERM and PDZ domain containing 2
chr11_+_4470525 0.16 ENST00000325719.4
OR52K2
olfactory receptor, family 52, subfamily K, member 2
chr1_-_65533390 0.16 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr17_-_70053866 0.16 ENST00000540802.1
RP11-84E24.2
RP11-84E24.2
chr11_-_65625330 0.16 ENST00000531407.1
CFL1
cofilin 1 (non-muscle)
chr5_+_102201687 0.16 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr22_-_30162924 0.16 ENST00000344318.3
ENST00000397781.3
ZMAT5
zinc finger, matrin-type 5
chr9_+_131683174 0.16 ENST00000372592.3
ENST00000428610.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr6_-_30080863 0.16 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr11_+_111169565 0.16 ENST00000528846.1
COLCA2
colorectal cancer associated 2
chr10_+_124030819 0.15 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr4_+_79567362 0.15 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr12_+_58003935 0.15 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr12_+_57849048 0.15 ENST00000266646.2
INHBE
inhibin, beta E
chr20_-_52612468 0.15 ENST00000422805.1
BCAS1
breast carcinoma amplified sequence 1
chr3_+_111260954 0.15 ENST00000283285.5
CD96
CD96 molecule
chr5_+_52776449 0.15 ENST00000396947.3
FST
follistatin
chr19_+_507299 0.15 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr5_-_146435572 0.15 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr5_-_146435501 0.15 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr19_+_13135386 0.15 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_-_37034028 0.15 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr9_-_34665983 0.15 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr7_+_150076406 0.15 ENST00000329630.5
ZNF775
zinc finger protein 775
chr5_+_140797296 0.14 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr2_-_158300556 0.14 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr2_-_73869508 0.14 ENST00000272425.3
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr6_-_154831779 0.14 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr17_+_73997796 0.14 ENST00000586261.1
CDK3
cyclin-dependent kinase 3
chr4_-_105416039 0.14 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr4_-_87770416 0.14 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr4_+_79567233 0.14 ENST00000514130.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr7_+_128312346 0.14 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
FAM71F2
family with sequence similarity 71, member F2
chr5_-_180242534 0.14 ENST00000333055.3
ENST00000513431.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr5_-_64064508 0.14 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr2_-_74776586 0.14 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr10_+_95372289 0.14 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr5_-_160279207 0.14 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr12_-_6484715 0.14 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr2_-_158182410 0.14 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr18_+_6729725 0.13 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr2_+_234602305 0.13 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr2_+_42104692 0.13 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr5_+_139505520 0.13 ENST00000333305.3
IGIP
IgA-inducing protein
chr5_-_146435694 0.13 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr7_+_73442457 0.13 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN
elastin
chr6_+_143447322 0.13 ENST00000458219.1
AIG1
androgen-induced 1
chr12_+_122242597 0.13 ENST00000267197.5
SETD1B
SET domain containing 1B
chr14_-_73360796 0.13 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr3_-_179754706 0.13 ENST00000465751.1
ENST00000467460.1
PEX5L
peroxisomal biogenesis factor 5-like
chr6_-_75828774 0.13 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr1_-_32210275 0.13 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr2_-_183387283 0.13 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_-_110933663 0.13 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chrX_-_32173579 0.13 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr6_-_76782371 0.12 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chr11_-_71810258 0.12 ENST00000544594.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr2_-_183387430 0.12 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_-_154943002 0.12 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr3_-_149510553 0.12 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr16_-_3306587 0.12 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV
Mediterranean fever
chr2_+_65663812 0.12 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr17_+_59477233 0.12 ENST00000240328.3
TBX2
T-box 2
chr10_-_104178857 0.12 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr17_+_80014359 0.12 ENST00000578168.1
GPS1
G protein pathway suppressor 1
chr19_+_41119794 0.12 ENST00000593463.1
LTBP4
latent transforming growth factor beta binding protein 4
chr8_+_9953061 0.11 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr20_+_35090150 0.11 ENST00000340491.4
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr3_-_114343039 0.11 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_+_100867486 0.11 ENST00000548884.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr19_+_19431490 0.11 ENST00000392313.6
ENST00000262815.8
ENST00000609122.1
MAU2
MAU2 sister chromatid cohesion factor
chr11_-_124806297 0.11 ENST00000298251.4
HEPACAM
hepatic and glial cell adhesion molecule
chr1_+_154474689 0.11 ENST00000368482.4
TDRD10
tudor domain containing 10
chr1_+_95286151 0.11 ENST00000467909.1
ENST00000422520.2
ENST00000532427.1
SLC44A3
solute carrier family 44, member 3
chr20_+_34129770 0.11 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3
ERGIC and golgi 3
chr1_-_201390846 0.11 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1
troponin I type 1 (skeletal, slow)
chr21_-_28215332 0.11 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr17_+_67590125 0.11 ENST00000591334.1
AC003051.1
AC003051.1
chrX_+_38420623 0.11 ENST00000378482.2
TSPAN7
tetraspanin 7
chr1_-_166944561 0.11 ENST00000271417.3
ILDR2
immunoglobulin-like domain containing receptor 2
chr15_-_88799661 0.11 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr1_-_205391178 0.11 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr18_+_32173276 0.11 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.4 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.4 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.5 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.1 0.5 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.1 0.3 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0070253 somatostatin secretion(GO:0070253)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.1 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:1903284 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0072615 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.9 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185) carbon dioxide transmembrane transport(GO:0035378)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0042418 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0021557 optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.2 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.0 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812) B cell cytokine production(GO:0002368)
0.0 0.1 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.0 0.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.4 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.4 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.4 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.0 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly