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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PKNOX1_TGIF2

Z-value: 0.82

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
PKNOX1
ENSG00000160199.10 PBX/knotted 1 homeobox 1
TGIF2
ENSG00000118707.5 TGFB induced factor homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PKNOX1hg19_v2_chr21_+_44394620_443947370.751.5e-04Click!
TGIF2hg19_v2_chr20_+_35201857_352018910.408.3e-02Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_113885138 2.35 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr2_+_233925064 2.07 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr2_+_191208601 1.98 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr17_+_8316442 1.81 ENST00000582812.1
NDEL1
nudE neurodevelopment protein 1-like 1
chr17_-_39661849 1.64 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr10_+_28822636 1.55 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr2_-_203103185 1.54 ENST00000409205.1
SUMO1
small ubiquitin-like modifier 1
chr11_+_129245796 1.46 ENST00000281437.4
BARX2
BARX homeobox 2
chr5_-_132073111 1.44 ENST00000403231.1
KIF3A
kinesin family member 3A
chr14_-_23762777 1.41 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr3_-_33482002 1.30 ENST00000283628.5
ENST00000456378.1
UBP1
upstream binding protein 1 (LBP-1a)
chr3_-_142166846 1.29 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr9_-_132805430 1.21 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr7_-_156685841 1.21 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr18_+_54318566 1.20 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr18_+_54318893 1.17 ENST00000593058.1
WDR7
WD repeat domain 7
chr5_+_166711804 1.14 ENST00000518659.1
ENST00000545108.1
TENM2
teneurin transmembrane protein 2
chr22_-_37640277 1.14 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr11_-_107729504 1.13 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr12_+_62654155 1.11 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr16_-_79634595 1.06 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr8_-_99837856 1.05 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr22_+_17082732 1.03 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr21_+_38792602 1.02 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr17_+_78518617 1.01 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr3_-_142166796 1.01 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr11_+_131240373 1.00 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chr10_-_4720333 0.99 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr11_-_107729287 0.98 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr22_-_37640456 0.97 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_-_15114191 0.95 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_145549203 0.93 ENST00000355594.4
ENST00000544626.1
ANKRD35
ankyrin repeat domain 35
chr1_+_109756523 0.92 ENST00000234677.2
ENST00000369923.4
SARS
seryl-tRNA synthetase
chr3_-_52719810 0.91 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr17_-_39661947 0.90 ENST00000590425.1
KRT13
keratin 13
chr6_+_26124373 0.90 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr16_+_2588012 0.89 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr6_-_35656685 0.87 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr9_+_133454943 0.87 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr18_+_54318616 0.87 ENST00000254442.3
WDR7
WD repeat domain 7
chr9_-_134615326 0.87 ENST00000438647.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr10_+_51565188 0.86 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr4_+_159593418 0.86 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr2_+_29353520 0.83 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr4_-_114682224 0.79 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr1_-_214638146 0.79 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr2_+_113321939 0.76 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr7_+_70229899 0.76 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chr6_-_101329191 0.74 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr11_+_120207787 0.74 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr16_-_69418553 0.73 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr4_+_3076388 0.71 ENST00000355072.5
HTT
huntingtin
chr1_+_203765437 0.71 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr10_-_4720301 0.70 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chr2_-_74618907 0.69 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr19_+_2867325 0.68 ENST00000307635.2
ENST00000586426.1
ZNF556
zinc finger protein 556
chr4_-_140477910 0.68 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr16_+_2587998 0.67 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr2_-_203103281 0.66 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
SUMO1
small ubiquitin-like modifier 1
chr12_-_121734489 0.66 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr7_-_104909435 0.66 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr11_-_107729887 0.66 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr16_+_50776021 0.65 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr11_-_46867780 0.65 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5
cytoskeleton associated protein 5
chr2_+_219081817 0.65 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_-_61765732 0.64 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_+_69201923 0.64 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr3_-_33481835 0.64 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr1_+_63989004 0.64 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr9_+_111696664 0.64 ENST00000374624.3
ENST00000445175.1
FAM206A
family with sequence similarity 206, member A
chr18_-_54318353 0.62 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr2_+_62900986 0.62 ENST00000405015.3
ENST00000413434.1
ENST00000426940.1
ENST00000449820.1
EHBP1
EH domain binding protein 1
chr19_+_11909329 0.61 ENST00000323169.5
ENST00000450087.1
ZNF491
zinc finger protein 491
chr14_-_100842588 0.61 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS
tryptophanyl-tRNA synthetase
chr4_-_140477928 0.61 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr5_+_125758865 0.60 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr2_+_191208656 0.58 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr2_+_191208791 0.58 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_+_24285599 0.58 ENST00000471915.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr12_-_31479107 0.58 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr1_+_24286287 0.57 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr9_-_111696340 0.57 ENST00000374647.5
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr6_+_111195973 0.57 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr13_+_33160553 0.56 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr2_-_242242133 0.55 ENST00000430918.1
HDLBP
high density lipoprotein binding protein
chr5_+_43603229 0.54 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr8_+_11666649 0.53 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr12_+_57522692 0.53 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr15_+_68346501 0.51 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr15_-_77197620 0.51 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER
S-phase cyclin A-associated protein in the ER
chr9_-_130635741 0.51 ENST00000223836.10
AK1
adenylate kinase 1
chr4_+_26578293 0.51 ENST00000512840.1
TBC1D19
TBC1 domain family, member 19
chr6_-_131949200 0.50 ENST00000539158.1
ENST00000368058.1
MED23
mediator complex subunit 23
chr19_+_11877838 0.49 ENST00000357901.4
ENST00000454339.2
ZNF441
zinc finger protein 441
chr5_-_65018834 0.49 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr3_+_186692745 0.48 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_+_57050317 0.48 ENST00000301318.3
ENST00000591844.1
ZFP28
ZFP28 zinc finger protein
chr6_-_47010061 0.47 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr5_+_125758813 0.46 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr3_+_38017264 0.45 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr1_+_210406121 0.44 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr16_-_69418649 0.44 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr4_+_74347400 0.44 ENST00000226355.3
AFM
afamin
chr5_+_125759140 0.43 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr1_-_70671216 0.42 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr3_+_63897605 0.42 ENST00000487717.1
ATXN7
ataxin 7
chr6_-_47009996 0.41 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr5_-_154230130 0.41 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr17_-_34122596 0.41 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr14_+_62164340 0.41 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr3_-_142166904 0.41 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr9_-_123605177 0.40 ENST00000373904.5
ENST00000210313.3
PSMD5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr20_+_22034809 0.40 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr7_+_79765071 0.39 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr17_+_75396637 0.39 ENST00000590825.1
SEPT9
septin 9
chr14_+_61995722 0.38 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr1_+_77333117 0.38 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr12_+_97306295 0.37 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr17_-_29151686 0.37 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr10_-_124768300 0.37 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr2_+_201173667 0.36 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr12_+_10658489 0.36 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr16_-_89556942 0.35 ENST00000301030.4
ANKRD11
ankyrin repeat domain 11
chr3_-_52569023 0.35 ENST00000307076.4
NT5DC2
5'-nucleotidase domain containing 2
chr19_-_11849697 0.35 ENST00000586121.1
ENST00000431998.1
ENST00000341191.6
ENST00000545749.1
ENST00000440527.1
ZNF823
zinc finger protein 823
chr12_+_95611569 0.35 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr17_-_42767115 0.35 ENST00000315286.8
ENST00000588210.1
ENST00000457422.2
CCDC43
coiled-coil domain containing 43
chr20_-_36156264 0.35 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr8_-_141774467 0.34 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr21_+_30502806 0.34 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr16_+_2587965 0.34 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr4_+_57774042 0.34 ENST00000309042.7
REST
RE1-silencing transcription factor
chr2_+_223725652 0.34 ENST00000357430.3
ENST00000392066.3
ACSL3
acyl-CoA synthetase long-chain family member 3
chr11_-_119247004 0.34 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr18_-_67872891 0.33 ENST00000454359.1
ENST00000437017.1
RTTN
rotatin
chr15_+_43477455 0.33 ENST00000300213.4
CCNDBP1
cyclin D-type binding-protein 1
chr3_+_50284321 0.33 ENST00000451956.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr7_+_66205712 0.33 ENST00000451741.2
ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
KCTD7
RABGEF1
potassium channel tetramerization domain containing 7
RAB guanine nucleotide exchange factor (GEF) 1
chr19_-_12551849 0.33 ENST00000595562.1
ENST00000301547.5
CTD-3105H18.16
ZNF443
Uncharacterized protein
zinc finger protein 443
chr19_-_49496557 0.32 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr4_-_114682326 0.32 ENST00000505990.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr15_-_43785274 0.32 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr1_-_208417620 0.32 ENST00000367033.3
PLXNA2
plexin A2
chr5_-_55008101 0.32 ENST00000506624.1
ENST00000513275.1
ENST00000513993.1
SLC38A9
solute carrier family 38, member 9
chr12_+_57522439 0.32 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr10_-_16859442 0.32 ENST00000602389.1
ENST00000345264.5
RSU1
Ras suppressor protein 1
chr1_-_53163992 0.32 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chr1_+_205473784 0.31 ENST00000478560.1
ENST00000443813.2
CDK18
cyclin-dependent kinase 18
chr14_-_69619689 0.31 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5
DDB1 and CUL4 associated factor 5
chrX_-_101397433 0.31 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr6_-_131949305 0.31 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
MED23
mediator complex subunit 23
chr14_-_94759408 0.31 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr10_+_121485588 0.30 ENST00000361976.2
ENST00000369083.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr14_-_21492251 0.30 ENST00000554398.1
NDRG2
NDRG family member 2
chr2_+_175260514 0.30 ENST00000424069.1
ENST00000427038.1
SCRN3
secernin 3
chr15_-_76352069 0.30 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr12_-_67197760 0.30 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr1_+_222886694 0.30 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr3_-_111852128 0.30 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr1_-_54872059 0.30 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr18_-_46987000 0.30 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr5_-_55008136 0.30 ENST00000503891.1
ENST00000507109.1
SLC38A9
solute carrier family 38, member 9
chr12_-_31881944 0.29 ENST00000537562.1
ENST00000537960.1
ENST00000536761.1
ENST00000542781.1
ENST00000457428.2
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr10_+_49514698 0.29 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr6_-_52926539 0.29 ENST00000350082.5
ENST00000356971.3
ICK
intestinal cell (MAK-like) kinase
chr3_-_111852061 0.28 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr2_+_175260451 0.28 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3
secernin 3
chr7_+_106810165 0.28 ENST00000468401.1
ENST00000497535.1
ENST00000485846.1
HBP1
HMG-box transcription factor 1
chr14_-_21492113 0.28 ENST00000554094.1
NDRG2
NDRG family member 2
chr4_-_114682364 0.28 ENST00000511664.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr3_+_57875738 0.28 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr14_-_94759361 0.28 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr12_+_104458235 0.27 ENST00000229330.4
HCFC2
host cell factor C2
chr14_-_21493123 0.27 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr15_+_51200871 0.27 ENST00000560508.1
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
chr7_-_42276612 0.27 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr6_+_150070857 0.27 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr8_-_37411648 0.27 ENST00000519738.1
RP11-150O12.1
RP11-150O12.1
chr15_-_43559055 0.27 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr2_+_191208196 0.27 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr17_-_29151794 0.26 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr16_-_20817857 0.26 ENST00000563117.1
ERI2
ERI1 exoribonuclease family member 2
chr10_+_114710516 0.26 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr10_-_99052382 0.26 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr2_-_86790472 0.26 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr5_+_150406527 0.26 ENST00000520059.1
GPX3
glutathione peroxidase 3 (plasma)
chr1_-_205391178 0.26 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr16_+_4896659 0.26 ENST00000592120.1
UBN1
ubinuclein 1
chr6_-_119031228 0.26 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr17_+_39868577 0.26 ENST00000329402.3
GAST
gastrin
chr6_-_26027480 0.25 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr10_-_118765081 0.25 ENST00000392903.2
ENST00000355371.4
KIAA1598
KIAA1598
chr15_+_36871983 0.25 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chr11_+_193065 0.25 ENST00000342878.2
SCGB1C1
secretoglobin, family 1C, member 1
chr3_+_57875711 0.25 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr2_-_3504587 0.24 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr12_-_105478339 0.24 ENST00000424857.2
ENST00000258494.9
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr11_+_60552797 0.24 ENST00000308287.1
MS4A10
membrane-spanning 4-domains, subfamily A, member 10
chr1_+_246729724 0.24 ENST00000366513.4
ENST00000366512.3
CNST
consortin, connexin sorting protein
chr17_+_38296576 0.24 ENST00000264645.7
CASC3
cancer susceptibility candidate 3

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.4 2.2 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.4 2.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.5 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.3 0.9 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.3 1.2 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.3 1.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 2.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.7 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.2 0.7 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 0.6 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 2.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.2 1.0 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.2 0.8 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 1.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 0.8 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 1.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 2.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 2.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 1.9 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.9 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.7 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.3 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 1.0 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.3 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.5 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 1.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.3 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.3 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 1.4 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.1 0.3 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 1.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.4 GO:0061030 neural fold elevation formation(GO:0021502) elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.2 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.4 GO:0043201 response to leucine(GO:0043201)
0.1 0.6 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.3 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.8 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.2 GO:0051808 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 1.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.9 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 1.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.0 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.0 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.5 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:0060174 limb bud formation(GO:0060174)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.8 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.4 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 1.1 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 1.0 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 2.4 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.0 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.0 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.7 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.0 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.9 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.9 GO:0008038 neuron recognition(GO:0008038)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 1.8 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.4 1.4 GO:0016939 kinesin II complex(GO:0016939)
0.2 0.6 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.2 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 0.9 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 2.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 2.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 3.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0031105 septin complex(GO:0031105)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.7 3.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.6 1.9 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.5 1.8 GO:0070012 oligopeptidase activity(GO:0070012)
0.3 2.7 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 1.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 0.9 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.3 0.9 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 0.8 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.3 2.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 2.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.2 1.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 0.6 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 0.6 GO:0019808 polyamine binding(GO:0019808)
0.2 0.5 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.5 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.2 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.1 0.8 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 1.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 2.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.7 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0045159 myosin II binding(GO:0045159)
0.0 0.5 GO:0071253 connexin binding(GO:0071253)
0.0 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 2.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.8 PID ATM PATHWAY ATM pathway
0.0 2.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.9 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 1.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 3.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.0 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha