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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PKNOX2

Z-value: 0.64

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Transcription factors associated with PKNOX2

Gene Symbol Gene ID Gene Info
PKNOX2
ENSG00000165495.11 PBX/knotted 1 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PKNOX2hg19_v2_chr11_+_125034586_1250346040.445.0e-02Click!

Activity profile of PKNOX2 motif

Sorted Z-values of PKNOX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_101329191 1.50 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr17_+_8316442 1.40 ENST00000582812.1
NDEL1
nudE neurodevelopment protein 1-like 1
chr11_+_129245796 1.35 ENST00000281437.4
BARX2
BARX homeobox 2
chr3_-_33482002 1.31 ENST00000283628.5
ENST00000456378.1
UBP1
upstream binding protein 1 (LBP-1a)
chr10_+_28822636 1.29 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr16_+_2880369 1.26 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr3_-_52719810 1.21 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr10_-_101945771 1.13 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr16_+_2880157 1.11 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr2_-_61765732 1.07 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr19_+_57050317 1.00 ENST00000301318.3
ENST00000591844.1
ZFP28
ZFP28 zinc finger protein
chr12_+_62654155 1.00 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr2_+_191208601 0.98 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr4_+_169418255 0.94 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr9_+_133454943 0.92 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr8_-_99837856 0.91 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr5_-_132073111 0.87 ENST00000403231.1
KIF3A
kinesin family member 3A
chr4_+_3076388 0.81 ENST00000355072.5
HTT
huntingtin
chr16_+_2880296 0.80 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr13_-_48575376 0.79 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr11_+_120207787 0.78 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr4_-_157892055 0.78 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr4_-_157892167 0.77 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr6_+_26124373 0.76 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr17_+_78518617 0.71 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr18_+_54318566 0.70 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr16_+_2880254 0.69 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr12_+_62654119 0.68 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr9_+_131873842 0.68 ENST00000417728.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr22_+_17082732 0.68 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr9_-_132805430 0.66 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr2_+_113321939 0.64 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr2_+_219081817 0.63 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr4_-_157892498 0.62 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr6_-_149867122 0.62 ENST00000253329.2
PPIL4
peptidylprolyl isomerase (cyclophilin)-like 4
chr10_-_124768300 0.62 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr2_+_64681103 0.60 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr7_-_42276612 0.60 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr7_-_104909435 0.59 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr1_+_109756523 0.58 ENST00000234677.2
ENST00000369923.4
SARS
seryl-tRNA synthetase
chr10_+_51565188 0.58 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr4_+_128703295 0.57 ENST00000296464.4
ENST00000508549.1
HSPA4L
heat shock 70kDa protein 4-like
chr3_-_33481835 0.56 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr6_+_150070857 0.56 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr5_+_125758865 0.55 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr10_+_49514698 0.54 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr12_-_121734489 0.54 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr18_+_54318893 0.53 ENST00000593058.1
WDR7
WD repeat domain 7
chr14_+_61995722 0.53 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr6_+_111195973 0.53 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr2_+_196440692 0.52 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr16_+_50776021 0.52 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr2_-_202316169 0.51 ENST00000430254.1
TRAK2
trafficking protein, kinesin binding 2
chr3_+_186692745 0.51 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr11_+_12132117 0.50 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr9_+_128510454 0.50 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chr5_-_127873896 0.49 ENST00000502468.1
FBN2
fibrillin 2
chr12_+_69201923 0.49 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr18_+_54318616 0.48 ENST00000254442.3
WDR7
WD repeat domain 7
chr15_+_57668695 0.47 ENST00000281282.5
CGNL1
cingulin-like 1
chr1_-_179112189 0.47 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr21_-_32931290 0.46 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr1_+_145549203 0.45 ENST00000355594.4
ENST00000544626.1
ANKRD35
ankyrin repeat domain 35
chr18_-_67872891 0.45 ENST00000454359.1
ENST00000437017.1
RTTN
rotatin
chr4_+_140222609 0.45 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr17_-_29151686 0.45 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr12_+_13044787 0.44 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr5_+_125758813 0.43 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr8_+_11666649 0.41 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr11_-_46867780 0.41 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5
cytoskeleton associated protein 5
chr13_+_33160553 0.41 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr20_-_39946237 0.41 ENST00000441102.2
ENST00000559234.1
ZHX3
zinc fingers and homeoboxes 3
chr3_+_32147997 0.41 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr4_+_169418195 0.40 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr6_-_116575226 0.40 ENST00000420283.1
TSPYL4
TSPY-like 4
chr20_+_43514320 0.40 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr8_+_57124245 0.40 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr15_+_68346501 0.39 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr6_+_150070831 0.39 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr5_+_125759140 0.39 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr22_-_31885514 0.38 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr17_-_35969409 0.36 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr14_-_69619689 0.35 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5
DDB1 and CUL4 associated factor 5
chr1_-_54872059 0.35 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr11_-_8832521 0.34 ENST00000530438.1
ST5
suppression of tumorigenicity 5
chr11_-_59383617 0.34 ENST00000263847.1
OSBP
oxysterol binding protein
chr6_-_101329157 0.32 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr1_+_161736072 0.32 ENST00000367942.3
ATF6
activating transcription factor 6
chr6_+_138188378 0.32 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr5_-_81046904 0.32 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chrX_+_16804544 0.31 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr3_+_23244579 0.31 ENST00000452894.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr14_-_21994337 0.31 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chr8_+_133787586 0.30 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr17_-_29151794 0.30 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr11_-_74660065 0.29 ENST00000525407.1
ENST00000528219.1
ENST00000531852.1
XRRA1
X-ray radiation resistance associated 1
chr2_-_202316260 0.29 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr2_-_242842587 0.29 ENST00000404031.1
AC131097.4
Protein LOC285095
chr14_-_21492113 0.28 ENST00000554094.1
NDRG2
NDRG family member 2
chr11_-_19262486 0.26 ENST00000250024.4
E2F8
E2F transcription factor 8
chr1_-_35658736 0.25 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr5_+_118407053 0.25 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr2_-_219524193 0.25 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
ZNF142
zinc finger protein 142
chr3_+_23244780 0.25 ENST00000396703.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr3_-_101395936 0.23 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr5_-_81046922 0.23 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chrX_-_77225135 0.23 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr5_+_72509751 0.22 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr2_-_61765315 0.22 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr3_+_183899770 0.22 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr6_+_37225540 0.21 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr1_-_100598444 0.21 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr22_+_30279144 0.20 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
MTMR3
myotubularin related protein 3
chr15_+_33010175 0.20 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr22_-_30234218 0.20 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr18_-_54318353 0.19 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr9_+_98637954 0.19 ENST00000288985.7
ERCC6L2
excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2
chr3_-_52719912 0.18 ENST00000420148.1
PBRM1
polybromo 1
chr11_-_119247004 0.17 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr9_-_99637820 0.17 ENST00000289032.8
ENST00000535338.1
ZNF782
zinc finger protein 782
chr3_+_113667354 0.17 ENST00000491556.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr2_+_191208196 0.17 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr4_-_83483094 0.17 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr11_-_111741994 0.16 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr2_+_64681219 0.15 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chrX_-_80377162 0.14 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr5_+_78985673 0.13 ENST00000446378.2
CMYA5
cardiomyopathy associated 5
chr22_+_20905422 0.12 ENST00000424287.1
ENST00000423862.1
MED15
mediator complex subunit 15
chr5_-_81046841 0.11 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr10_+_70661014 0.11 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr2_+_128848740 0.11 ENST00000375990.3
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr6_-_37225391 0.11 ENST00000356757.2
TMEM217
transmembrane protein 217
chr3_+_14474178 0.11 ENST00000452775.1
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr1_-_179112173 0.10 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chrX_-_80377118 0.09 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr12_+_49621658 0.09 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr18_-_52626622 0.08 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr13_+_20268547 0.08 ENST00000601204.1
AL354808.2
AL354808.2
chr5_+_118406796 0.08 ENST00000503802.1
DMXL1
Dmx-like 1
chr17_-_4046257 0.07 ENST00000381638.2
ZZEF1
zinc finger, ZZ-type with EF-hand domain 1
chr22_+_20905269 0.07 ENST00000457322.1
MED15
mediator complex subunit 15
chr1_+_22778337 0.07 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr17_+_39868577 0.07 ENST00000329402.3
GAST
gastrin
chr1_+_113263199 0.06 ENST00000361886.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr11_-_1782625 0.06 ENST00000438213.1
CTSD
cathepsin D
chr6_+_108881012 0.06 ENST00000343882.6
FOXO3
forkhead box O3
chr16_+_88636789 0.06 ENST00000301011.5
ENST00000452588.2
ZC3H18
zinc finger CCCH-type containing 18
chr3_+_46742823 0.05 ENST00000326431.3
TMIE
transmembrane inner ear
chr2_+_128848881 0.04 ENST00000259253.6
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr9_+_6758109 0.04 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr8_+_31496809 0.02 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr6_-_32140886 0.02 ENST00000395496.1
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr6_+_155334780 0.01 ENST00000538270.1
ENST00000535231.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chrX_-_128788914 0.00 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr19_+_41281060 0.00 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 1.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.3 0.8 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.3 0.8 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.2 0.6 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.8 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.2 0.6 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.2 0.5 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 0.5 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.2 0.5 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 0.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.4 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 2.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.5 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.3 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.5 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.5 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 2.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.7 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 1.0 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 1.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 1.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 3.9 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.6 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.3 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:1903980 positive regulation of microglial cell activation(GO:1903980)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.2 0.9 GO:0016939 kinesin II complex(GO:0016939)
0.2 0.6 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.3 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.6 GO:0044754 autolysosome(GO:0044754)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.1 GO:0097542 ciliary tip(GO:0097542)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 1.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 0.7 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.2 1.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.2 0.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.5 GO:0019808 polyamine binding(GO:0019808)
0.2 1.8 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.2 0.5 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 0.8 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 1.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 1.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 2.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.8 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis