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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PLAG1

Z-value: 0.46

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Transcription factors associated with PLAG1

Gene Symbol Gene ID Gene Info
PLAG1
ENSG00000181690.3 PLAG1 zinc finger

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PLAG1hg19_v2_chr8_-_57123815_57123867-0.632.7e-03Click!

Activity profile of PLAG1 motif

Sorted Z-values of PLAG1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_55795493 0.96 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr19_+_41725140 0.90 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr11_+_123430948 0.85 ENST00000529432.1
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr5_-_59189545 0.80 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_12419905 0.79 ENST00000535731.1
LRP6
low density lipoprotein receptor-related protein 6
chr19_+_41725088 0.71 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr6_+_7727030 0.64 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chr12_+_105724613 0.60 ENST00000549934.2
C12orf75
chromosome 12 open reading frame 75
chr12_+_105724414 0.59 ENST00000443585.1
ENST00000552457.1
ENST00000549893.1
C12orf75
chromosome 12 open reading frame 75
chr8_+_21912328 0.59 ENST00000432128.1
ENST00000443491.2
ENST00000517600.1
ENST00000523782.2
DMTN
dematin actin binding protein
chr11_-_6440283 0.58 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr17_+_30593195 0.56 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chrY_+_22737604 0.51 ENST00000361365.2
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr12_+_58005204 0.50 ENST00000286494.4
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr17_-_3599327 0.50 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr16_-_3030283 0.49 ENST00000572619.1
ENST00000574415.1
ENST00000440027.2
ENST00000572059.1
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr10_-_21786179 0.49 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr16_+_31483451 0.48 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr16_+_31483374 0.47 ENST00000394863.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr1_-_204654481 0.44 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chr4_-_38666430 0.42 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr19_+_40697514 0.41 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr19_-_41220957 0.41 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
ADCK4
aarF domain containing kinase 4
chr1_-_23886285 0.40 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr12_-_52715179 0.40 ENST00000293670.3
KRT83
keratin 83
chr3_+_19988736 0.38 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr12_+_79258547 0.37 ENST00000457153.2
SYT1
synaptotagmin I
chr4_-_155533787 0.37 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr8_-_23261589 0.36 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2
lysyl oxidase-like 2
chr22_-_30642782 0.36 ENST00000249075.3
LIF
leukemia inhibitory factor
chr16_+_46723552 0.36 ENST00000219097.2
ENST00000568364.2
ORC6
origin recognition complex, subunit 6
chr6_+_32812568 0.34 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr12_+_79258444 0.34 ENST00000261205.4
SYT1
synaptotagmin I
chr12_-_58131931 0.34 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr12_+_57998595 0.34 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
DTX3
deltex homolog 3 (Drosophila)
chr17_+_39968926 0.34 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FKBP10
FK506 binding protein 10, 65 kDa
chr12_+_56546363 0.33 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr17_+_48046538 0.33 ENST00000240306.3
DLX4
distal-less homeobox 4
chr14_+_79745682 0.33 ENST00000557594.1
NRXN3
neurexin 3
chr16_-_29910365 0.32 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr19_+_39904168 0.31 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr19_+_41083064 0.31 ENST00000595631.1
SHKBP1
SH3KBP1 binding protein 1
chr1_+_62902308 0.30 ENST00000339950.4
USP1
ubiquitin specific peptidase 1
chr12_+_57998400 0.30 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr12_-_121973974 0.30 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B
lysine (K)-specific demethylase 2B
chr9_+_2621950 0.30 ENST00000382096.1
VLDLR
very low density lipoprotein receptor
chr22_-_30642728 0.30 ENST00000403987.3
LIF
leukemia inhibitory factor
chr7_+_73703728 0.30 ENST00000361545.5
ENST00000223398.6
CLIP2
CAP-GLY domain containing linker protein 2
chr16_-_29910853 0.30 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr11_+_64053311 0.29 ENST00000540370.1
GPR137
G protein-coupled receptor 137
chr6_+_31730773 0.29 ENST00000415669.2
ENST00000425424.1
SAPCD1
suppressor APC domain containing 1
chr1_-_201438282 0.28 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr17_+_48046671 0.28 ENST00000505318.2
DLX4
distal-less homeobox 4
chr19_-_14201776 0.28 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr14_+_79745746 0.27 ENST00000281127.7
NRXN3
neurexin 3
chr17_-_56065540 0.26 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr14_-_25519095 0.26 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr14_-_75079294 0.26 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr9_+_34652164 0.26 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr12_-_12419703 0.25 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr11_-_57282349 0.25 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr19_-_40790729 0.24 ENST00000423127.1
ENST00000583859.1
ENST00000456441.1
ENST00000452077.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr12_+_121163538 0.23 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr19_-_56048456 0.23 ENST00000413299.1
SBK2
SH3 domain binding kinase family, member 2
chr11_+_66610883 0.23 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr14_-_51562037 0.22 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr2_-_74619152 0.22 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr19_+_40973049 0.22 ENST00000598249.1
ENST00000338932.3
ENST00000344104.3
SPTBN4
spectrin, beta, non-erythrocytic 4
chr14_+_45605127 0.22 ENST00000556036.1
ENST00000267430.5
FANCM
Fanconi anemia, complementation group M
chr5_-_137368726 0.21 ENST00000420893.2
ENST00000425075.2
FAM13B
family with sequence similarity 13, member B
chr11_-_72852320 0.21 ENST00000422375.1
FCHSD2
FCH and double SH3 domains 2
chr12_-_122018859 0.21 ENST00000536437.1
ENST00000377071.4
ENST00000538046.2
KDM2B
lysine (K)-specific demethylase 2B
chr12_-_122018346 0.20 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr1_-_212003556 0.20 ENST00000366996.1
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr14_+_79746249 0.19 ENST00000428277.2
NRXN3
neurexin 3
chr17_-_4607335 0.19 ENST00000570571.1
ENST00000575101.1
ENST00000436683.2
ENST00000574876.1
PELP1
proline, glutamate and leucine rich protein 1
chr17_-_56591321 0.19 ENST00000583243.1
MTMR4
myotubularin related protein 4
chr16_+_2198604 0.19 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr5_+_75699149 0.18 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr2_-_74618964 0.18 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr19_-_40790993 0.18 ENST00000596634.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr9_-_34662651 0.18 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr19_+_18283959 0.16 ENST00000597802.2
IFI30
interferon, gamma-inducible protein 30
chr17_-_1420006 0.16 ENST00000320345.6
ENST00000406424.4
INPP5K
inositol polyphosphate-5-phosphatase K
chrX_+_51927919 0.15 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chrX_-_16887963 0.15 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr2_-_178937478 0.15 ENST00000286063.6
PDE11A
phosphodiesterase 11A
chr9_+_2621798 0.15 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr19_-_6424283 0.15 ENST00000595258.1
ENST00000595548.1
KHSRP
KH-type splicing regulatory protein
chr19_-_42759300 0.14 ENST00000222329.4
ERF
Ets2 repressor factor
chr14_+_57857262 0.14 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr21_-_15755446 0.14 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr5_-_176936817 0.14 ENST00000502885.1
ENST00000506493.1
DOK3
docking protein 3
chr15_+_29131103 0.14 ENST00000558402.1
ENST00000558330.1
APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr5_-_137368708 0.14 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr11_+_1651033 0.13 ENST00000399676.2
KRTAP5-5
keratin associated protein 5-5
chr9_-_123476719 0.13 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr1_-_24469602 0.13 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr4_-_114682936 0.13 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr19_-_51054299 0.12 ENST00000599957.1
LRRC4B
leucine rich repeat containing 4B
chr16_+_31128978 0.11 ENST00000448516.2
ENST00000219797.4
KAT8
K(lysine) acetyltransferase 8
chr19_+_45116921 0.10 ENST00000402988.1
IGSF23
immunoglobulin superfamily, member 23
chr17_+_48351785 0.10 ENST00000507382.1
TMEM92
transmembrane protein 92
chr14_+_45605157 0.10 ENST00000542564.2
FANCM
Fanconi anemia, complementation group M
chr6_-_97345689 0.10 ENST00000316149.7
NDUFAF4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr3_-_58419537 0.10 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB
pyruvate dehydrogenase (lipoamide) beta
chr1_-_115632035 0.09 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr14_-_75330537 0.09 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2
prospero homeobox 2
chr17_+_20483037 0.09 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr4_+_55095264 0.08 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr4_-_5890145 0.08 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr4_+_55095428 0.08 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr4_-_114682719 0.08 ENST00000394522.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr15_+_92397051 0.08 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr7_+_75024337 0.07 ENST00000450434.1
TRIM73
tripartite motif containing 73
chr10_-_99447024 0.07 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr17_-_1588101 0.07 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
PRPF8
pre-mRNA processing factor 8
chr3_-_184971817 0.07 ENST00000440662.1
ENST00000456310.1
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr19_+_38924316 0.07 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1
ryanodine receptor 1 (skeletal)
chr11_-_73309112 0.07 ENST00000450446.2
FAM168A
family with sequence similarity 168, member A
chr2_-_128399706 0.07 ENST00000426981.1
LIMS2
LIM and senescent cell antigen-like domains 2
chr19_-_35264089 0.07 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
ZNF599
zinc finger protein 599
chr5_-_150467221 0.07 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr2_-_85788652 0.06 ENST00000430215.3
GGCX
gamma-glutamyl carboxylase
chr10_-_126849626 0.06 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chrX_-_48776292 0.06 ENST00000376509.4
PIM2
pim-2 oncogene
chr17_+_73106035 0.06 ENST00000581078.1
ENST00000582136.1
ENST00000245543.1
ARMC7
armadillo repeat containing 7
chr2_-_86850949 0.06 ENST00000237455.4
RNF103
ring finger protein 103
chr19_+_56116771 0.06 ENST00000568956.1
ZNF865
zinc finger protein 865
chr10_-_102890883 0.06 ENST00000445873.1
TLX1NB
TLX1 neighbor
chr5_-_135701164 0.06 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr14_-_25519317 0.06 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)
chr9_-_123476612 0.05 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr6_-_37467628 0.05 ENST00000373408.3
CCDC167
coiled-coil domain containing 167
chr16_+_31191431 0.05 ENST00000254108.7
ENST00000380244.3
ENST00000568685.1
FUS
fused in sarcoma
chr2_+_153191706 0.05 ENST00000288670.9
FMNL2
formin-like 2
chr3_+_32726620 0.05 ENST00000331889.6
ENST00000328834.5
CNOT10
CCR4-NOT transcription complex, subunit 10
chr11_-_11374904 0.05 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr17_+_38278530 0.05 ENST00000398532.4
MSL1
male-specific lethal 1 homolog (Drosophila)
chr16_+_4896659 0.04 ENST00000592120.1
UBN1
ubinuclein 1
chrX_-_45060135 0.04 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr16_+_29984962 0.04 ENST00000308893.4
TAOK2
TAO kinase 2
chr13_+_53602894 0.04 ENST00000219022.2
OLFM4
olfactomedin 4
chr3_-_15374033 0.04 ENST00000253688.5
ENST00000383791.3
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr3_+_14989076 0.04 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr18_-_51750948 0.04 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr2_+_157292933 0.04 ENST00000540309.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr11_-_73309228 0.04 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr3_-_19988462 0.04 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr3_-_138312971 0.04 ENST00000485115.1
ENST00000484888.1
ENST00000468900.1
ENST00000542237.1
ENST00000481834.1
CEP70
centrosomal protein 70kDa
chr5_+_159895275 0.04 ENST00000517927.1
MIR146A
microRNA 146a
chr8_-_145641864 0.03 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_-_94079648 0.03 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr3_-_116163830 0.03 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr17_-_4889508 0.03 ENST00000574606.2
CAMTA2
calmodulin binding transcription activator 2
chr10_-_75173785 0.03 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
ANXA7
annexin A7
chr20_+_62716348 0.03 ENST00000349451.3
OPRL1
opiate receptor-like 1
chr16_-_18812746 0.03 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1
RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr13_+_47127293 0.03 ENST00000311191.6
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr16_+_56485402 0.03 ENST00000566157.1
ENST00000562150.1
ENST00000561646.1
ENST00000568397.1
OGFOD1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr1_+_22962948 0.03 ENST00000374642.3
C1QA
complement component 1, q subcomponent, A chain
chr1_-_27701307 0.03 ENST00000270879.4
ENST00000354982.2
FCN3
ficolin (collagen/fibrinogen domain containing) 3
chr5_+_10353780 0.02 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr3_+_32726774 0.02 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chrX_+_23682379 0.02 ENST00000379349.1
PRDX4
peroxiredoxin 4
chr6_+_31683117 0.02 ENST00000375825.3
ENST00000375824.1
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr4_-_114682597 0.02 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr1_+_173446405 0.02 ENST00000340385.5
PRDX6
peroxiredoxin 6
chr11_-_72852958 0.01 ENST00000458644.2
FCHSD2
FCH and double SH3 domains 2
chrX_+_152599604 0.01 ENST00000370251.3
ENST00000421401.3
ZNF275
zinc finger protein 275
chr17_-_76719807 0.01 ENST00000589297.1
CYTH1
cytohesin 1
chr12_-_112819896 0.01 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECTD4
HECT domain containing E3 ubiquitin protein ligase 4
chr1_-_151138422 0.01 ENST00000440902.2
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1
chr11_-_71293921 0.01 ENST00000398530.1
KRTAP5-11
keratin associated protein 5-11
chr2_-_152955537 0.00 ENST00000201943.5
ENST00000539935.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr6_-_71012773 0.00 ENST00000370496.3
ENST00000357250.6
COL9A1
collagen, type IX, alpha 1
chr6_+_106534192 0.00 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr7_-_76039000 0.00 ENST00000275560.3
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chrX_+_153146127 0.00 ENST00000452593.1
ENST00000357566.1
LCA10
Putative lung carcinoma-associated protein 10
chr14_-_106518922 0.00 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr1_-_92949505 0.00 ENST00000370332.1
GFI1
growth factor independent 1 transcription repressor

Network of associatons between targets according to the STRING database.

First level regulatory network of PLAG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.3 1.6 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.2 0.6 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.6 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 0.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 1.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0018277 protein deamination(GO:0018277)
0.1 0.3 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.2 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.4 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.4 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.6 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 1.0 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.4 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.5 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.6 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.7 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.6 GO:0033643 host cell part(GO:0033643)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 0.7 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events