Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for POU1F1

Z-value: 0.52

Motif logo

Transcription factors associated with POU1F1

Gene Symbol Gene ID Gene Info
ENSG00000064835.6 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU1F1hg19_v2_chr3_-_87325728_87325739-0.464.4e-02Click!

Activity profile of POU1F1 motif

Sorted Z-values of POU1F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_78518617 1.12 ENST00000537330.1
ENST00000570891.1
regulatory associated protein of MTOR, complex 1
chr12_+_78359999 0.88 ENST00000550503.1
neuron navigator 3
chr12_-_106480587 0.73 ENST00000548902.1
NUAK family, SNF1-like kinase, 1
chr15_+_101417919 0.69 ENST00000561338.1
aldehyde dehydrogenase 1 family, member A3
chr9_-_95055923 0.67 ENST00000430417.1
isoleucyl-tRNA synthetase
chr5_+_179135246 0.66 ENST00000508787.1
calnexin
chr17_-_57158523 0.65 ENST00000581468.1
tripartite motif containing 37
chr17_-_5321549 0.60 ENST00000572809.1
nucleoporin 88kDa
chr18_-_74839891 0.55 ENST00000581878.1
myelin basic protein
chr15_-_75748143 0.53 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3 transcription regulator family member A
chr12_-_25150373 0.49 ENST00000549828.1
chromosome 12 open reading frame 77
chr15_-_72521017 0.48 ENST00000561609.1
pyruvate kinase, muscle
chr1_-_183538319 0.48 ENST00000420553.1
ENST00000419402.1
neutrophil cytosolic factor 2
chr7_-_30009542 0.48 ENST00000438497.1
secernin 1
chr7_+_134528635 0.48 ENST00000445569.2
caldesmon 1
chr21_-_27423339 0.47 ENST00000415997.1
amyloid beta (A4) precursor protein
chr2_+_161993465 0.47 ENST00000457476.1
TRAF family member-associated NFKB activator
chr6_+_26087646 0.47 ENST00000309234.6
hemochromatosis
chr16_-_2379688 0.47 ENST00000567910.1
ATP-binding cassette, sub-family A (ABC1), member 3
chr2_-_190044480 0.46 ENST00000374866.3
collagen, type V, alpha 2
chr15_+_67418047 0.45 ENST00000540846.2
SMAD family member 3
chr7_-_35013217 0.43 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr10_-_14596140 0.43 ENST00000496330.1
family with sequence similarity 107, member B
chr3_+_160939050 0.43 ENST00000493066.1
ENST00000351193.2
ENST00000472947.1
ENST00000463518.1
NMD3 ribosome export adaptor
chrX_-_71458802 0.42 ENST00000373657.1
ENST00000334463.3
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr1_+_117963209 0.42 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr8_+_98900132 0.41 ENST00000520016.1
matrilin 2
chr6_+_26087509 0.41 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
hemochromatosis
chr4_+_169552748 0.41 ENST00000504519.1
ENST00000512127.1
palladin, cytoskeletal associated protein
chr17_+_46189311 0.40 ENST00000582481.1
sorting nexin 11
chr8_-_30670384 0.38 ENST00000221138.4
ENST00000518243.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr10_+_94352956 0.37 ENST00000260731.3
kinesin family member 11
chr4_+_37978891 0.37 ENST00000446803.2
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr15_+_65843130 0.37 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr10_-_27529486 0.37 ENST00000375888.1
acyl-CoA binding domain containing 5
chr12_-_58220078 0.37 ENST00000549039.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr9_-_95056010 0.37 ENST00000443024.2
isoleucyl-tRNA synthetase
chrX_+_56590002 0.36 ENST00000338222.5
ubiquilin 2
chr6_+_26104104 0.36 ENST00000377803.2
histone cluster 1, H4c
chr2_+_172309634 0.36 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr1_-_211307404 0.36 ENST00000367007.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr10_-_74283694 0.36 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
mitochondrial calcium uptake 1
chr9_-_95055956 0.36 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
isoleucyl-tRNA synthetase
chr1_+_76251912 0.36 ENST00000370826.3
Rab geranylgeranyltransferase, beta subunit
chr16_+_15489629 0.35 ENST00000396385.3
MPV17 mitochondrial membrane protein-like
chr17_+_45728427 0.34 ENST00000540627.1
karyopherin (importin) beta 1
chr1_-_205091115 0.34 ENST00000264515.6
ENST00000367164.1
retinoblastoma binding protein 5
chr22_-_43010859 0.33 ENST00000339677.6
polymerase (DNA-directed), delta interacting protein 3
chr14_+_31046959 0.32 ENST00000547532.1
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr18_+_21269556 0.32 ENST00000399516.3
laminin, alpha 3
chr2_-_17981462 0.32 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr4_+_25162253 0.31 ENST00000512921.1
phosphatidylinositol 4-kinase type 2 beta
chr11_-_107729504 0.31 ENST00000265836.7
solute carrier family 35, member F2
chr12_+_47610315 0.31 ENST00000548348.1
ENST00000549500.1
PC-esterase domain containing 1B
chr12_+_34175398 0.30 ENST00000538927.1
ALG10, alpha-1,2-glucosyltransferase
chr12_+_38710555 0.30 ENST00000551464.1
ALG10B, alpha-1,2-glucosyltransferase
chr11_+_100784231 0.29 ENST00000531183.1
Rho GTPase activating protein 42
chr14_+_55493920 0.28 ENST00000395472.2
ENST00000555846.1
suppressor of cytokine signaling 4
chr11_-_107729287 0.28 ENST00000375682.4
solute carrier family 35, member F2
chr5_+_55147205 0.28 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
interleukin 31 receptor A
chr12_+_113796347 0.28 ENST00000545182.2
ENST00000280800.3
phospholipase B domain containing 2
chr18_+_21269404 0.28 ENST00000313654.9
laminin, alpha 3
chr17_-_6524159 0.28 ENST00000589033.1
KIAA0753
chr12_+_26164645 0.28 ENST00000542004.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr16_+_21623392 0.28 ENST00000562961.1
methyltransferase like 9
chr10_-_115904361 0.28 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chr1_+_66820058 0.27 ENST00000480109.2
phosphodiesterase 4B, cAMP-specific
chr14_+_62164340 0.27 ENST00000557538.1
ENST00000539097.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr1_-_154580616 0.27 ENST00000368474.4
adenosine deaminase, RNA-specific
chr22_+_23487513 0.27 ENST00000263116.2
ENST00000341989.4
RAB36, member RAS oncogene family
chr10_+_116697946 0.27 ENST00000298746.3
TruB pseudouridine (psi) synthase family member 1
chr16_-_66764119 0.27 ENST00000569320.1
dynein, cytoplasmic 1, light intermediate chain 2
chr3_+_193311056 0.27 ENST00000419435.1
optic atrophy 1 (autosomal dominant)
chr12_-_49581152 0.26 ENST00000550811.1
tubulin, alpha 1a
chrX_-_77225135 0.26 ENST00000458128.1
phosphoglycerate mutase family member 4
chrX_-_106243294 0.26 ENST00000255495.7
MORC family CW-type zinc finger 4
chr5_-_94417562 0.26 ENST00000505465.1
multiple C2 domains, transmembrane 1
chr7_+_13141010 0.25 ENST00000443947.1
AC011288.2
chr3_+_193310969 0.25 ENST00000392437.1
optic atrophy 1 (autosomal dominant)
chr12_-_67197760 0.24 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
glutamate receptor interacting protein 1
chrX_+_84258832 0.24 ENST00000373173.2
apolipoprotein O-like
chr3_+_193311105 0.24 ENST00000392436.2
optic atrophy 1 (autosomal dominant)
chr2_-_219157219 0.24 ENST00000445635.1
ENST00000413976.1
transmembrane BAX inhibitor motif containing 1
chr7_+_115862858 0.23 ENST00000393481.2
testis derived transcript (3 LIM domains)
chr10_+_62538089 0.23 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr10_-_113943447 0.23 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
glycerol-3-phosphate acyltransferase, mitochondrial
chr3_-_145940214 0.23 ENST00000481701.1
phospholipid scramblase 4
chr3_-_195076933 0.23 ENST00000423531.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr6_-_152639479 0.23 ENST00000356820.4
spectrin repeat containing, nuclear envelope 1
chr1_+_112938803 0.22 ENST00000271277.6
CTTNBP2 N-terminal like
chr17_+_61086917 0.22 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr5_-_94417339 0.22 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
multiple C2 domains, transmembrane 1
chr3_-_48130707 0.22 ENST00000360240.6
ENST00000383737.4
microtubule-associated protein 4
chr6_-_109702885 0.22 ENST00000504373.1
CD164 molecule, sialomucin
chr14_+_61449076 0.22 ENST00000526105.1
solute carrier family 38, member 6
chr14_+_61654271 0.21 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr14_-_80697396 0.21 ENST00000557010.1
deiodinase, iodothyronine, type II
chr5_+_140762268 0.21 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr12_-_118796910 0.21 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr17_+_29664830 0.21 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr6_-_152623231 0.21 ENST00000540663.1
ENST00000537033.1
spectrin repeat containing, nuclear envelope 1
chr19_+_52873166 0.21 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
zinc finger protein 880
chr5_-_94417186 0.20 ENST00000312216.8
ENST00000512425.1
multiple C2 domains, transmembrane 1
chr14_+_101295638 0.20 ENST00000523671.2
maternally expressed 3 (non-protein coding)
chr10_+_122610687 0.20 ENST00000263461.6
WD repeat domain 11
chrX_+_70503526 0.19 ENST00000413858.1
ENST00000450092.1
non-POU domain containing, octamer-binding
chr6_-_136788001 0.19 ENST00000544465.1
microtubule-associated protein 7
chr3_+_193310918 0.19 ENST00000361908.3
ENST00000392438.3
ENST00000361510.2
ENST00000361715.2
ENST00000361828.2
ENST00000361150.2
optic atrophy 1 (autosomal dominant)
chr12_+_69753448 0.19 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS domain containing 4
chr2_-_190446738 0.18 ENST00000427419.1
ENST00000455320.1
solute carrier family 40 (iron-regulated transporter), member 1
chr4_-_85654615 0.18 ENST00000514711.1
WD repeat and FYVE domain containing 3
chr1_-_212965104 0.18 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1, MIS12 kinetochore complex component
chr3_+_138340067 0.18 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr3_-_27498235 0.18 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_-_14026063 0.18 ENST00000443608.1
ENST00000438956.1
ets variant 1
chr3_+_187930429 0.17 ENST00000420410.1
LIM domain containing preferred translocation partner in lipoma
chr10_+_64133934 0.17 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
zinc finger protein 365
chr4_+_3344141 0.17 ENST00000306648.7
regulator of G-protein signaling 12
chr16_+_15489603 0.17 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr3_+_108308845 0.17 ENST00000479138.1
DAZ interacting zinc finger protein 3
chr18_-_59274139 0.17 ENST00000586949.1
RP11-879F14.2
chr12_-_52761262 0.17 ENST00000257901.3
keratin 85
chr1_-_183559693 0.17 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
neutrophil cytosolic factor 2
chr3_+_186692745 0.17 ENST00000438590.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr11_+_12399071 0.17 ENST00000539723.1
ENST00000550549.1
parvin, alpha
chr2_+_161993412 0.16 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr9_-_33473882 0.16 ENST00000455041.2
ENST00000353159.2
ENST00000297990.4
ENST00000379471.2
nucleolar protein 6 (RNA-associated)
chr16_-_66583994 0.16 ENST00000564917.1
thymidine kinase 2, mitochondrial
chr1_+_40862501 0.16 ENST00000539317.1
small ArfGAP2
chr7_+_129932974 0.16 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr14_+_55494323 0.16 ENST00000339298.2
suppressor of cytokine signaling 4
chr11_-_128894053 0.15 ENST00000392657.3
Rho GTPase activating protein 32
chrX_-_15288154 0.15 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ankyrin repeat and SOCS box containing 9
chr12_-_95510743 0.15 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr8_-_141774467 0.15 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr8_-_145754428 0.15 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
chromosome 8 open reading frame 82
chr10_+_17270214 0.15 ENST00000544301.1
vimentin
chr4_+_96012585 0.15 ENST00000502683.1
bone morphogenetic protein receptor, type IB
chr6_+_158733692 0.15 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chr15_-_75748115 0.14 ENST00000360439.4
SIN3 transcription regulator family member A
chr19_+_19144384 0.14 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr1_-_109584608 0.14 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WD repeat domain 47
chr6_+_133561725 0.14 ENST00000452339.2
eyes absent homolog 4 (Drosophila)
chr4_+_119809984 0.14 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
synaptopodin 2
chr10_+_51572408 0.14 ENST00000374082.1
nuclear receptor coactivator 4
chr4_+_95128748 0.14 ENST00000359052.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr9_-_85882145 0.13 ENST00000328788.1
FERM domain containing 3
chr2_+_232135245 0.13 ENST00000446447.1
armadillo repeat containing 9
chr9_+_117373486 0.13 ENST00000288502.4
ENST00000374049.4
chromosome 9 open reading frame 91
chr10_-_13043697 0.13 ENST00000378825.3
coiled-coil domain containing 3
chr12_-_12714025 0.13 ENST00000539940.1
dual specificity phosphatase 16
chrX_+_150565038 0.13 ENST00000370361.1
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr4_-_103746683 0.13 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr16_+_48278178 0.12 ENST00000285737.4
ENST00000535754.1
lon peptidase 2, peroxisomal
chr2_+_208414985 0.12 ENST00000414681.1
cAMP responsive element binding protein 1
chr2_-_14541060 0.12 ENST00000418420.1
ENST00000417751.1
long intergenic non-protein coding RNA 276
chr2_-_45795145 0.12 ENST00000535761.1
S1 RNA binding domain 1
chr12_-_118796971 0.12 ENST00000542902.1
TAO kinase 3
chrX_-_106243451 0.11 ENST00000355610.4
ENST00000535534.1
MORC family CW-type zinc finger 4
chr17_+_12569306 0.11 ENST00000425538.1
myocardin
chr11_+_2405833 0.11 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr4_+_119810134 0.11 ENST00000434046.2
synaptopodin 2
chr20_-_43589109 0.11 ENST00000372813.3
translocase of outer mitochondrial membrane 34
chr1_-_45988542 0.11 ENST00000424390.1
peroxiredoxin 1
chr5_+_156696362 0.11 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr4_-_74486109 0.11 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr17_-_38821373 0.11 ENST00000394052.3
keratin 222
chr14_-_78083112 0.11 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr5_+_111755280 0.11 ENST00000600409.1
EPB41L4A antisense RNA 2 (head to head)
chr5_-_94417314 0.10 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr4_-_100356551 0.10 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr16_+_19535235 0.10 ENST00000565376.2
ENST00000396208.2
centriolar coiled coil protein 110kDa
chr11_-_117186946 0.10 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr1_+_81106951 0.10 ENST00000443565.1
RP5-887A10.1
chr6_+_106988986 0.10 ENST00000457437.1
ENST00000535438.1
absent in melanoma 1
chr22_+_31460091 0.10 ENST00000432777.1
ENST00000422839.1
smoothelin
chr4_-_118006697 0.10 ENST00000310754.4
translocation associated membrane protein 1-like 1
chr10_-_75226166 0.10 ENST00000544628.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr22_-_43010928 0.10 ENST00000348657.2
ENST00000252115.5
polymerase (DNA-directed), delta interacting protein 3
chr6_+_4087664 0.10 ENST00000430835.2
chromosome 6 open reading frame 201
chr3_-_145940126 0.09 ENST00000498625.1
phospholipid scramblase 4
chr20_-_29896388 0.09 ENST00000400549.1
defensin, beta 116
chr17_+_12569472 0.09 ENST00000343344.4
myocardin
chr2_-_220264703 0.09 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
aspartyl aminopeptidase
chr4_+_74347400 0.09 ENST00000226355.3
afamin
chr12_+_64798095 0.09 ENST00000332707.5
exportin, tRNA
chr11_-_111649074 0.09 ENST00000534218.1
RP11-108O10.2
chr16_-_70835034 0.09 ENST00000261776.5
Vac14 homolog (S. cerevisiae)
chr6_-_26235206 0.09 ENST00000244534.5
histone cluster 1, H1d
chr6_+_26440700 0.09 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr12_-_12714006 0.09 ENST00000541207.1
dual specificity phosphatase 16
chr16_-_66584059 0.08 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chr19_-_35264089 0.08 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
zinc finger protein 599
chr4_+_96012614 0.08 ENST00000264568.4
bone morphogenetic protein receptor, type IB
chr1_-_160924589 0.08 ENST00000368029.3
intelectin 2
chr3_+_130650738 0.08 ENST00000504612.1
ATPase, Ca++ transporting, type 2C, member 1
chr14_-_90420862 0.08 ENST00000556005.1
ENST00000555872.1
EF-hand calcium binding domain 11
chr6_+_114178512 0.07 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr10_-_14050522 0.07 ENST00000342409.2
FERM domain containing 4A
chr7_-_14026123 0.07 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ets variant 1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU1F1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.3 0.9 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.2 0.9 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 0.7 GO:0060166 olfactory pit development(GO:0060166)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.7 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 1.1 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.5 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 1.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.4 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0021502 neural fold elevation formation(GO:0021502) elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.2 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.6 GO:0035973 aggrephagy(GO:0035973)
0.0 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.4 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.7 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.0 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.5 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.1 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0032010 phagolysosome(GO:0032010)
0.1 1.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.5 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 1.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 1.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.6 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.9 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0097689 iron channel activity(GO:0097689)
0.1 0.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.5 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus