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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for POU3F3_POU3F4

Z-value: 0.47

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Transcription factors associated with POU3F3_POU3F4

Gene Symbol Gene ID Gene Info
POU3F3
ENSG00000198914.2 POU class 3 homeobox 3
POU3F4
ENSG00000196767.4 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F3hg19_v2_chr2_+_105471969_1054719690.029.4e-01Click!

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_209602156 1.90 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
MIR205HG
MIR205 host gene (non-protein coding)
chr8_-_49833978 1.82 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr16_+_55600580 1.71 ENST00000457326.2
CAPNS2
calpain, small subunit 2
chr1_+_209602609 1.49 ENST00000458250.1
MIR205HG
MIR205 host gene (non-protein coding)
chr8_-_49834299 1.42 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr17_-_39093672 1.32 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr3_+_189507460 0.78 ENST00000434928.1
TP63
tumor protein p63
chr18_+_47088401 0.77 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr5_+_125758865 0.73 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_+_125758813 0.73 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chrX_-_32173579 0.67 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr3_+_189507523 0.66 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr8_-_119634141 0.64 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
SAMD12
sterile alpha motif domain containing 12
chr12_-_50616382 0.62 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr3_+_189507432 0.57 ENST00000354600.5
TP63
tumor protein p63
chr4_+_154622652 0.56 ENST00000260010.6
TLR2
toll-like receptor 2
chr22_+_39101728 0.55 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr3_-_74570291 0.55 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr19_-_18632861 0.52 ENST00000262809.4
ELL
elongation factor RNA polymerase II
chr7_-_100026280 0.50 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr3_-_107777208 0.47 ENST00000398258.3
CD47
CD47 molecule
chr3_-_151034734 0.46 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr5_+_125759140 0.46 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr11_-_104827425 0.46 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr12_-_111926342 0.45 ENST00000389154.3
ATXN2
ataxin 2
chr1_+_59775752 0.45 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr5_-_42811986 0.45 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr22_+_45148432 0.44 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
ARHGAP8
Rho GTPase activating protein 8
chr10_+_24738355 0.43 ENST00000307544.6
KIAA1217
KIAA1217
chr3_+_53528659 0.42 ENST00000350061.5
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr1_+_101702417 0.40 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr14_-_21270995 0.39 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr22_-_39268308 0.38 ENST00000407418.3
CBX6
chromobox homolog 6
chr14_+_101297740 0.37 ENST00000555928.1
MEG3
maternally expressed 3 (non-protein coding)
chr8_+_61591337 0.37 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr5_-_42812143 0.37 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr4_-_110723134 0.37 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr2_+_210444142 0.37 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr17_+_66255310 0.36 ENST00000448504.2
ARSG
arylsulfatase G
chr11_-_26593677 0.35 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr12_-_10324716 0.34 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr4_-_87281224 0.33 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr5_+_140753444 0.33 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr22_-_43036607 0.32 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr17_-_7387524 0.32 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr6_+_143447322 0.32 ENST00000458219.1
AIG1
androgen-induced 1
chr4_-_110723335 0.32 ENST00000394634.2
CFI
complement factor I
chr1_+_78383813 0.31 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr1_+_104198377 0.31 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr2_+_210443993 0.30 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr13_-_26795840 0.30 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr4_-_110723194 0.30 ENST00000394635.3
CFI
complement factor I
chr5_-_160279207 0.30 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr19_-_20748614 0.29 ENST00000596797.1
ZNF737
zinc finger protein 737
chr9_-_34458531 0.28 ENST00000379089.1
ENST00000379087.1
ENST00000379084.1
ENST00000379081.1
ENST00000379080.1
ENST00000422409.1
ENST00000379078.1
ENST00000445726.1
ENST00000297620.4
FAM219A
family with sequence similarity 219, member A
chr4_+_30723003 0.28 ENST00000543491.1
PCDH7
protocadherin 7
chr17_+_34171081 0.28 ENST00000585577.1
TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr4_+_186990298 0.28 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr14_-_21270561 0.27 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr11_-_125366018 0.26 ENST00000527534.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr17_+_7387677 0.26 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chrX_+_105936982 0.25 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr18_-_52989217 0.25 ENST00000570287.2
TCF4
transcription factor 4
chr18_-_24722995 0.25 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr11_-_26593649 0.25 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr1_+_61547894 0.25 ENST00000403491.3
NFIA
nuclear factor I/A
chr2_+_135596180 0.25 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr3_-_168865522 0.24 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr8_+_11666649 0.24 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr11_-_2906979 0.24 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr3_-_196911002 0.24 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr3_-_100558953 0.24 ENST00000533795.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr10_-_75676400 0.23 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr6_-_11779403 0.23 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr5_+_96212185 0.22 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chrX_-_80457385 0.22 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5
high mobility group nucleosome binding domain 5
chr7_+_119913688 0.22 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr12_+_6554021 0.22 ENST00000266557.3
CD27
CD27 molecule
chrM_+_5824 0.22 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr1_-_111743285 0.22 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr12_-_56753858 0.21 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr9_-_14322319 0.21 ENST00000606230.1
NFIB
nuclear factor I/B
chr2_-_224702740 0.21 ENST00000444408.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr6_-_76782371 0.20 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chr5_+_36608422 0.20 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_57092381 0.20 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr2_+_135596106 0.19 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_+_25205446 0.19 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr6_-_134861089 0.19 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr20_+_58203664 0.18 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr13_+_109248500 0.18 ENST00000356711.2
MYO16
myosin XVI
chr12_-_42631529 0.18 ENST00000548917.1
YAF2
YY1 associated factor 2
chr11_-_111649015 0.17 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr8_+_38244638 0.17 ENST00000526356.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr1_-_104238912 0.17 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr12_+_109785708 0.17 ENST00000310903.5
MYO1H
myosin IH
chr6_-_11779014 0.17 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr4_-_102268708 0.17 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_104239076 0.17 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr11_-_62369291 0.17 ENST00000278823.2
MTA2
metastasis associated 1 family, member 2
chr5_+_140710061 0.16 ENST00000517417.1
ENST00000378105.3
PCDHGA1
protocadherin gamma subfamily A, 1
chr3_+_177545563 0.16 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr1_-_1297157 0.15 ENST00000477278.2
MXRA8
matrix-remodelling associated 8
chr3_-_196242233 0.15 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr20_+_58179582 0.15 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr12_+_25205568 0.15 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr10_-_94003003 0.15 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr17_-_66951474 0.15 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr13_-_46716969 0.15 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr15_-_42343388 0.15 ENST00000399518.3
PLA2G4E
phospholipase A2, group IVE
chrX_+_149867681 0.15 ENST00000438018.1
ENST00000436701.1
MTMR1
myotubularin related protein 1
chr1_+_104293028 0.14 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr5_+_119867159 0.14 ENST00000505123.1
PRR16
proline rich 16
chr16_-_30064244 0.14 ENST00000571269.1
ENST00000561666.1
FAM57B
family with sequence similarity 57, member B
chr1_-_2458026 0.14 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr10_-_128359074 0.14 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr9_-_14180778 0.14 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr2_-_239140011 0.14 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chr6_-_49712147 0.14 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr3_-_141747439 0.14 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr13_-_46679144 0.14 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr11_-_105010320 0.14 ENST00000532895.1
ENST00000530950.1
CARD18
caspase recruitment domain family, member 18
chr4_-_52883786 0.14 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr6_-_47277634 0.14 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr16_+_75690093 0.14 ENST00000564671.2
TERF2IP
telomeric repeat binding factor 2, interacting protein
chr2_+_40973618 0.13 ENST00000420187.1
AC007317.1
AC007317.1
chr18_-_52989525 0.13 ENST00000457482.3
TCF4
transcription factor 4
chr12_+_25205666 0.13 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr13_+_102142296 0.13 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_-_207078154 0.13 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr14_+_21249200 0.13 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr5_+_140782351 0.13 ENST00000573521.1
PCDHGA9
protocadherin gamma subfamily A, 9
chrX_+_105855160 0.13 ENST00000372544.2
ENST00000372548.4
CXorf57
chromosome X open reading frame 57
chr4_-_100356291 0.13 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_-_168155730 0.12 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_-_26220366 0.12 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr8_-_25281747 0.12 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr19_-_14201507 0.12 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr16_-_56223480 0.12 ENST00000565155.1
RP11-461O7.1
RP11-461O7.1
chr9_+_34458771 0.12 ENST00000437363.1
ENST00000242317.4
DNAI1
dynein, axonemal, intermediate chain 1
chr4_-_44653636 0.12 ENST00000415895.4
ENST00000332990.5
YIPF7
Yip1 domain family, member 7
chr6_-_49712091 0.12 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr2_+_87135076 0.12 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr11_-_118305921 0.12 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr2_-_207078086 0.12 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr2_+_166095898 0.12 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr16_+_30064444 0.12 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA
aldolase A, fructose-bisphosphate
chr2_-_88285309 0.12 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr12_+_59989918 0.12 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chrX_+_78003204 0.12 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chrX_+_54834004 0.11 ENST00000375068.1
MAGED2
melanoma antigen family D, 2
chr3_+_111805182 0.11 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52
chromosome 3 open reading frame 52
chr12_-_9885888 0.11 ENST00000327839.3
CLECL1
C-type lectin-like 1
chr1_+_19923454 0.11 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1
MINOS1
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr1_+_117544366 0.11 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr14_-_24682652 0.11 ENST00000556387.1
ENST00000530611.1
ENST00000609024.1
ENST00000530996.1
TM9SF1
TM9SF1
CHMP4A
transmembrane 9 superfamily member 1
Transmembrane 9 superfamily member 1
charged multivesicular body protein 4A
chr5_-_127418573 0.11 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
CTC-228N24.3
chr4_-_137842536 0.11 ENST00000512039.1
RP11-138I17.1
RP11-138I17.1
chr5_+_140602904 0.11 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr6_-_2634820 0.11 ENST00000296847.3
C6orf195
chromosome 6 open reading frame 195
chr4_-_168155577 0.11 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr10_+_71561704 0.11 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr4_+_126315091 0.11 ENST00000335110.5
FAT4
FAT atypical cadherin 4
chr10_+_90484301 0.10 ENST00000404190.1
LIPK
lipase, family member K
chr2_-_183387283 0.10 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr12_+_25205628 0.10 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr13_+_103459704 0.10 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr16_+_30064411 0.10 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr7_+_17414360 0.10 ENST00000419463.1
AC019117.1
AC019117.1
chr4_-_186570679 0.10 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr19_-_44123734 0.10 ENST00000598676.1
ZNF428
zinc finger protein 428
chr10_-_49813090 0.10 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr21_-_37914898 0.10 ENST00000399136.1
CLDN14
claudin 14
chr5_-_41794663 0.10 ENST00000510634.1
OXCT1
3-oxoacid CoA transferase 1
chr1_+_104159999 0.10 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr5_-_11588907 0.10 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr14_+_70918874 0.10 ENST00000603540.1
ADAM21
ADAM metallopeptidase domain 21
chr2_+_7017796 0.10 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr11_-_111649074 0.10 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr6_-_11779174 0.09 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr2_-_183387430 0.09 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr15_+_76352178 0.09 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr14_-_60952739 0.09 ENST00000555476.1
ENST00000321731.3
C14orf39
chromosome 14 open reading frame 39
chr6_+_44355257 0.09 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr13_+_102104980 0.09 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr6_+_74171301 0.09 ENST00000415954.2
ENST00000498286.1
ENST00000370305.1
ENST00000370300.4
MTO1
mitochondrial tRNA translation optimization 1
chrX_+_47053208 0.09 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1
ubiquitin-like modifier activating enzyme 1
chr2_-_183387064 0.09 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr5_-_160973649 0.09 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr1_+_73771844 0.09 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
RP4-598G3.1
chr11_-_82782861 0.09 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr10_+_696000 0.09 ENST00000381489.5
PRR26
proline rich 26
chr10_+_114710211 0.09 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_-_89664595 0.09 ENST00000355754.6
GBP4
guanylate binding protein 4
chr8_-_59412717 0.09 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr22_-_41032668 0.09 ENST00000355630.3
ENST00000396617.3
ENST00000402042.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr16_+_27279526 0.09 ENST00000566854.1
CTD-3203P2.2
HCG1815999; Uncharacterized protein
chr5_-_41794313 0.09 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr11_-_102496063 0.09 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr6_-_66417107 0.08 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 2.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 0.8 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 0.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.3 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.3 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 0.4 GO:0021553 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) olfactory nerve development(GO:0021553)
0.1 0.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.5 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:0002200 somatic diversification of immune receptors(GO:0002200) somatic diversification of immunoglobulins(GO:0016445)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.6 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.7 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 2.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.6 GO:0071723 lipopolysaccharide receptor activity(GO:0001875) lipopeptide binding(GO:0071723)
0.1 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.0 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.0 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 3.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.0 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.0 GO:0043532 angiostatin binding(GO:0043532)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 5.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters