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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for POU6F2

Z-value: 0.55

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Transcription factors associated with POU6F2

Gene Symbol Gene ID Gene Info
POU6F2
ENSG00000106536.15 POU class 6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU6F2hg19_v2_chr7_+_39017504_390175980.243.1e-01Click!

Activity profile of POU6F2 motif

Sorted Z-values of POU6F2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_156486120 2.44 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr15_-_54025300 1.08 ENST00000559418.1
WDR72
WD repeat domain 72
chr11_-_27494279 1.02 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr11_-_27494309 1.01 ENST00000389858.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chrX_+_10031499 1.01 ENST00000454666.1
WWC3
WWC family member 3
chr3_-_127541194 0.93 ENST00000453507.2
MGLL
monoglyceride lipase
chr10_+_94352956 0.92 ENST00000260731.3
KIF11
kinesin family member 11
chr6_+_151646800 0.89 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr7_+_6655225 0.84 ENST00000457543.3
ZNF853
zinc finger protein 853
chr11_-_31531121 0.77 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr4_+_78829479 0.76 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr3_+_141106458 0.76 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr15_+_80351910 0.72 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr20_+_5987890 0.71 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chrX_-_106243294 0.71 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr6_-_111136299 0.69 ENST00000457688.1
CDK19
cyclin-dependent kinase 19
chr2_+_44502597 0.69 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr15_+_80351977 0.69 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr1_-_193028426 0.68 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr11_+_47293795 0.67 ENST00000422579.1
MADD
MAP-kinase activating death domain
chr13_+_78315466 0.66 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr1_+_193028717 0.65 ENST00000415442.2
ENST00000506303.1
TROVE2
TROVE domain family, member 2
chr17_+_73539339 0.65 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr7_-_14029283 0.65 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr16_+_53133070 0.64 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_+_200011711 0.64 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chrX_-_106243451 0.64 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr2_+_44502630 0.64 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr3_-_33686925 0.63 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr5_+_159343688 0.63 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr10_-_92681033 0.62 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr16_-_54962704 0.61 ENST00000502066.2
ENST00000560912.1
ENST00000558952.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr20_+_42187682 0.60 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr1_-_193028621 0.59 ENST00000367455.4
ENST00000367454.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr1_-_204329013 0.59 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr17_-_47786375 0.59 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr14_+_39583427 0.58 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2
gem (nuclear organelle) associated protein 2
chr1_+_193028552 0.57 ENST00000400968.2
ENST00000432079.1
TROVE2
TROVE domain family, member 2
chr3_+_159557637 0.56 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr13_+_98612446 0.56 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
IPO5
importin 5
chr17_-_2117600 0.56 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr3_+_141105705 0.55 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr17_+_4613918 0.55 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2
arrestin, beta 2
chr6_+_76330355 0.55 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr1_-_193028632 0.55 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr4_+_175204865 0.54 ENST00000505124.1
CEP44
centrosomal protein 44kDa
chr2_-_61697862 0.53 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr6_-_111804905 0.52 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chrX_+_86772787 0.51 ENST00000373114.4
KLHL4
kelch-like family member 4
chr13_-_30160925 0.49 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr10_+_35484793 0.48 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr16_-_54962415 0.48 ENST00000501177.3
ENST00000559598.2
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr8_-_90996837 0.47 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr17_-_33390667 0.46 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr6_-_111136513 0.45 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr12_+_54332535 0.45 ENST00000243056.3
HOXC13
homeobox C13
chrX_+_86772707 0.45 ENST00000373119.4
KLHL4
kelch-like family member 4
chr20_+_42187608 0.42 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr12_+_28410128 0.42 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr12_-_15815626 0.42 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr3_-_33686743 0.41 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr1_+_46379254 0.40 ENST00000372008.2
MAST2
microtubule associated serine/threonine kinase 2
chr7_-_55620433 0.38 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr17_+_4613776 0.38 ENST00000269260.2
ARRB2
arrestin, beta 2
chr2_+_102721023 0.37 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr13_+_78315528 0.37 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chrX_-_38186775 0.37 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR
retinitis pigmentosa GTPase regulator
chr11_+_30344595 0.36 ENST00000282032.3
ARL14EP
ADP-ribosylation factor-like 14 effector protein
chr4_+_175204818 0.36 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr20_+_58515417 0.34 ENST00000360816.3
FAM217B
family with sequence similarity 217, member B
chr7_-_16840820 0.34 ENST00000450569.1
AGR2
anterior gradient 2
chr11_+_101918153 0.34 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr1_-_159832438 0.34 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chrX_-_38186811 0.33 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr13_-_44735393 0.33 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr17_-_71223839 0.33 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr17_-_46716647 0.32 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr15_-_37393406 0.31 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr3_-_11610255 0.31 ENST00000424529.2
VGLL4
vestigial like 4 (Drosophila)
chr11_+_45918092 0.31 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr1_-_47655686 0.30 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr9_+_131902346 0.30 ENST00000432124.1
ENST00000435305.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr6_+_4087664 0.30 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr2_+_29001711 0.30 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr9_+_131902283 0.29 ENST00000436883.1
ENST00000414510.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr10_-_94257512 0.28 ENST00000371581.5
IDE
insulin-degrading enzyme
chr5_+_137722255 0.28 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr8_+_22424551 0.27 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr8_-_142012169 0.27 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr8_+_19536083 0.27 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr11_+_7598239 0.26 ENST00000525597.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_42396274 0.26 ENST00000438528.3
SMIM19
small integral membrane protein 19
chr17_-_19290483 0.26 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr8_+_92261516 0.26 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr7_-_14028488 0.25 ENST00000405358.4
ETV1
ets variant 1
chr1_-_21606013 0.24 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr6_-_8064567 0.24 ENST00000543936.1
ENST00000397457.2
BLOC1S5
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr8_+_26150628 0.24 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr11_+_31531291 0.24 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr2_-_217560248 0.23 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr22_-_30642728 0.22 ENST00000403987.3
LIF
leukemia inhibitory factor
chr9_-_13165457 0.21 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr7_+_129015671 0.21 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr5_+_136070614 0.20 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr16_-_54962625 0.20 ENST00000559432.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr1_+_62439037 0.20 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr10_-_21186144 0.20 ENST00000377119.1
NEBL
nebulette
chr8_+_77593474 0.20 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr15_+_67390920 0.19 ENST00000559092.1
ENST00000560175.1
SMAD3
SMAD family member 3
chr2_+_7118755 0.19 ENST00000433456.1
RNF144A
ring finger protein 144A
chr1_-_31666767 0.19 ENST00000530145.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr22_+_20905422 0.18 ENST00000424287.1
ENST00000423862.1
MED15
mediator complex subunit 15
chr6_-_74231444 0.18 ENST00000331523.2
ENST00000356303.2
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr4_-_175204765 0.18 ENST00000513696.1
ENST00000503293.1
FBXO8
F-box protein 8
chr12_-_52946923 0.17 ENST00000267119.5
KRT71
keratin 71
chr7_+_116660246 0.17 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr12_-_100378006 0.17 ENST00000547776.2
ENST00000329257.7
ENST00000547010.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chrX_-_23926004 0.16 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr17_+_12569306 0.15 ENST00000425538.1
MYOCD
myocardin
chr16_+_31885079 0.15 ENST00000300870.10
ENST00000394846.3
ZNF267
zinc finger protein 267
chr20_-_45035223 0.15 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2
engulfment and cell motility 2
chr5_+_115177178 0.14 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr7_+_115862858 0.14 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr11_+_71544246 0.14 ENST00000328698.1
DEFB108B
defensin, beta 108B
chr2_+_128403439 0.14 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr3_+_130648842 0.13 ENST00000508297.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr14_-_27066960 0.13 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr17_-_19290117 0.12 ENST00000497081.2
MFAP4
microfibrillar-associated protein 4
chr17_-_40337470 0.12 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr1_+_10271674 0.12 ENST00000377086.1
KIF1B
kinesin family member 1B
chr21_+_17443521 0.12 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr15_+_96904487 0.11 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr12_-_53045948 0.11 ENST00000309680.3
KRT2
keratin 2
chr17_-_38911580 0.10 ENST00000312150.4
KRT25
keratin 25
chr15_+_58702742 0.10 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chrX_-_19988382 0.10 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23
chromosome X open reading frame 23
chr4_-_66536196 0.10 ENST00000511294.1
EPHA5
EPH receptor A5
chr2_-_217559517 0.10 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr17_+_12569472 0.09 ENST00000343344.4
MYOCD
myocardin
chr2_+_128403720 0.09 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chr17_+_73539232 0.09 ENST00000580925.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr4_-_66536057 0.09 ENST00000273854.3
EPHA5
EPH receptor A5
chr21_-_35899113 0.09 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr5_-_54988448 0.08 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr7_+_129015484 0.07 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr17_+_48243352 0.07 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
SGCA
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
chr15_+_101402041 0.07 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr2_-_177684007 0.07 ENST00000451851.1
AC092162.1
AC092162.1
chr15_+_75080883 0.07 ENST00000567571.1
CSK
c-src tyrosine kinase
chr15_-_33447055 0.07 ENST00000559047.1
ENST00000561249.1
FMN1
formin 1
chr19_-_47137942 0.07 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chrX_-_21676442 0.07 ENST00000379499.2
KLHL34
kelch-like family member 34
chr6_-_89927151 0.07 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr22_+_20905269 0.06 ENST00000457322.1
MED15
mediator complex subunit 15
chr8_+_77593448 0.06 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr4_+_40198527 0.06 ENST00000381799.5
RHOH
ras homolog family member H
chr1_-_11024258 0.05 ENST00000418570.2
C1orf127
chromosome 1 open reading frame 127
chr4_+_110834033 0.05 ENST00000509793.1
ENST00000265171.5
EGF
epidermal growth factor
chr8_-_10512569 0.03 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr9_-_34729457 0.03 ENST00000378788.3
FAM205A
family with sequence similarity 205, member A
chrX_-_18690210 0.03 ENST00000379984.3
RS1
retinoschisin 1
chr7_-_5465045 0.03 ENST00000399434.2
TNRC18
trinucleotide repeat containing 18
chr21_+_17443434 0.03 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr1_+_175036966 0.03 ENST00000239462.4
TNN
tenascin N
chr9_+_130853715 0.02 ENST00000373066.5
ENST00000432073.2
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr12_-_106697974 0.02 ENST00000553039.1
CKAP4
cytoskeleton-associated protein 4
chr2_-_8715616 0.02 ENST00000418358.1
AC011747.3
AC011747.3
chr17_+_18086392 0.02 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr14_+_101359265 0.02 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chrX_-_13835147 0.02 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr6_-_33160231 0.01 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr22_+_20905286 0.01 ENST00000428629.1
MED15
mediator complex subunit 15
chr4_-_22444733 0.01 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr4_+_86525299 0.01 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr4_+_66536248 0.00 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr14_+_59100774 0.00 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU6F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.6 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 0.9 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.2 1.3 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.6 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.8 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.7 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.6 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.5 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 1.1 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.6 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 1.4 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 1.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.4 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 2.3 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.5 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 2.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.8 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 3.1 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.2 0.7 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.6 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 1.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.3 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.8 GO:0070628 proteasome binding(GO:0070628)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 2.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors