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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PPARG

Z-value: 1.00

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Transcription factors associated with PPARG

Gene Symbol Gene ID Gene Info
PPARG
ENSG00000132170.15 peroxisome proliferator activated receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARGhg19_v2_chr3_+_12330560_123305790.126.2e-01Click!

Activity profile of PPARG motif

Sorted Z-values of PPARG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_49864746 3.15 ENST00000598810.1
TEAD2
TEA domain family member 2
chr19_-_55740632 2.27 ENST00000327042.4
TMEM86B
transmembrane protein 86B
chr19_+_49661079 1.99 ENST00000355712.5
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr19_+_49661037 1.77 ENST00000427978.2
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr19_-_1592828 1.71 ENST00000592012.1
MBD3
methyl-CpG binding domain protein 3
chr20_+_43803517 1.66 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr2_+_120187465 1.59 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37
chr19_+_50016411 1.48 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_+_2923619 1.48 ENST00000380574.1
SLC22A18
solute carrier family 22, member 18
chr14_+_21152259 1.47 ENST00000555835.1
ENST00000336811.6
RNASE4
ANG
ribonuclease, RNase A family, 4
angiogenin, ribonuclease, RNase A family, 5
chr11_+_2923499 1.38 ENST00000449793.2
SLC22A18
solute carrier family 22, member 18
chr11_-_117698787 1.38 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr9_-_33447584 1.37 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr16_+_1203194 1.37 ENST00000348261.5
ENST00000358590.4
CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr15_-_41120896 1.30 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr22_+_50312316 1.29 ENST00000328268.4
CRELD2
cysteine-rich with EGF-like domains 2
chr22_+_50312274 1.25 ENST00000404488.3
CRELD2
cysteine-rich with EGF-like domains 2
chr4_+_74735102 1.23 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr16_+_770975 1.22 ENST00000569529.1
ENST00000564000.1
ENST00000219535.3
FAM173A
family with sequence similarity 173, member A
chr19_+_49660997 1.21 ENST00000598691.1
ENST00000252826.5
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chrX_-_51812268 1.19 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B
melanoma antigen family D, 4B
chr10_+_114135952 1.19 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_-_11115877 1.17 ENST00000490101.1
SRM
spermidine synthase
chr3_+_48507210 1.15 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr19_+_544034 1.13 ENST00000592501.1
ENST00000264553.3
GZMM
granzyme M (lymphocyte met-ase 1)
chr5_+_175223313 1.10 ENST00000359546.4
CPLX2
complexin 2
chr19_+_50016610 1.06 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr9_+_139847347 1.06 ENST00000371632.3
LCN12
lipocalin 12
chr22_-_24641027 1.05 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
GGT5
gamma-glutamyltransferase 5
chr15_+_41056218 1.05 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr6_-_64029879 1.01 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr19_+_507299 1.01 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr11_+_46740730 1.01 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr6_-_30080876 1.00 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr11_+_308143 0.99 ENST00000399817.4
IFITM2
interferon induced transmembrane protein 2
chr11_-_74022658 0.99 ENST00000427714.2
ENST00000331597.4
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr15_-_41166414 0.98 ENST00000220507.4
RHOV
ras homolog family member V
chr17_-_34207295 0.98 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr14_+_105992906 0.97 ENST00000392519.2
TMEM121
transmembrane protein 121
chr8_-_145115584 0.93 ENST00000426825.1
OPLAH
5-oxoprolinase (ATP-hydrolysing)
chrX_+_51928002 0.92 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr1_-_111970353 0.92 ENST00000369732.3
OVGP1
oviductal glycoprotein 1, 120kDa
chr3_+_48507621 0.92 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr17_-_76975925 0.92 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr6_-_30080863 0.91 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr19_-_1592652 0.90 ENST00000156825.1
ENST00000434436.3
MBD3
methyl-CpG binding domain protein 3
chr9_+_101984577 0.90 ENST00000223641.4
SEC61B
Sec61 beta subunit
chr19_+_850985 0.88 ENST00000590230.1
ELANE
elastase, neutrophil expressed
chr14_+_105953246 0.88 ENST00000392531.3
CRIP1
cysteine-rich protein 1 (intestinal)
chr17_+_39975544 0.87 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr8_+_145729465 0.86 ENST00000394955.2
GPT
glutamic-pyruvate transaminase (alanine aminotransferase)
chr11_+_61522844 0.86 ENST00000265460.5
MYRF
myelin regulatory factor
chr16_+_84209738 0.85 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr19_-_44031341 0.85 ENST00000600651.1
ETHE1
ethylmalonic encephalopathy 1
chr16_-_3137080 0.85 ENST00000574387.1
ENST00000571404.1
RP11-473M20.9
RP11-473M20.9
chr15_+_41056255 0.85 ENST00000561160.1
ENST00000559445.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr22_-_50689786 0.84 ENST00000216271.5
HDAC10
histone deacetylase 10
chr8_-_145701718 0.84 ENST00000377317.4
FOXH1
forkhead box H1
chr14_+_105953204 0.83 ENST00000409393.2
CRIP1
cysteine-rich protein 1 (intestinal)
chr6_-_25832254 0.82 ENST00000476801.1
ENST00000244527.4
ENST00000427328.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chr4_+_926171 0.81 ENST00000507319.1
ENST00000264771.4
TMEM175
transmembrane protein 175
chr3_+_49058444 0.81 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr19_+_56154913 0.80 ENST00000270451.5
ENST00000588537.1
ZNF581
zinc finger protein 581
chr12_+_123459127 0.79 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr11_-_1593150 0.78 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr11_+_126225789 0.77 ENST00000530591.1
ENST00000534083.1
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr16_+_89984287 0.77 ENST00000555147.1
MC1R
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr14_+_24630465 0.76 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr17_-_48450534 0.74 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
MRPL27
mitochondrial ribosomal protein L27
chr11_+_844406 0.74 ENST00000397404.1
TSPAN4
tetraspanin 4
chr19_-_51071302 0.73 ENST00000389201.3
ENST00000600381.1
LRRC4B
leucine rich repeat containing 4B
chr9_+_139846708 0.73 ENST00000371633.3
LCN12
lipocalin 12
chr19_-_44031375 0.72 ENST00000292147.2
ETHE1
ethylmalonic encephalopathy 1
chr7_+_75511362 0.72 ENST00000428119.1
RHBDD2
rhomboid domain containing 2
chr6_-_49712147 0.70 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr19_+_7968728 0.70 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
MAP2K7
mitogen-activated protein kinase kinase 7
chr19_-_46405861 0.69 ENST00000322217.5
MYPOP
Myb-related transcription factor, partner of profilin
chr22_-_21579843 0.69 ENST00000405188.4
GGT2
gamma-glutamyltransferase 2
chr19_-_55919087 0.69 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S
ubiquitin-conjugating enzyme E2S
chr16_-_67969888 0.69 ENST00000574576.2
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr17_-_7082861 0.68 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr16_+_777739 0.67 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr19_+_36239576 0.67 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr11_-_1771797 0.67 ENST00000340134.4
IFITM10
interferon induced transmembrane protein 10
chr5_+_178977546 0.66 ENST00000319449.4
ENST00000377001.2
RUFY1
RUN and FYVE domain containing 1
chr8_-_145642267 0.66 ENST00000301305.3
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_-_6502304 0.65 ENST00000540257.1
ENST00000594276.1
ENST00000594075.1
ENST00000600216.1
ENST00000596926.1
TUBB4A
tubulin, beta 4A class IVa
chr8_-_145641864 0.65 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr11_-_2924720 0.65 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr20_+_44563267 0.64 ENST00000372409.3
PCIF1
PDX1 C-terminal inhibiting factor 1
chr2_+_220306745 0.64 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr11_-_64901978 0.63 ENST00000294256.8
ENST00000377190.3
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chrX_+_54947229 0.61 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr11_+_61248583 0.61 ENST00000432063.2
ENST00000338608.2
PPP1R32
protein phosphatase 1, regulatory subunit 32
chr16_-_21289627 0.61 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr22_-_24096630 0.61 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr3_+_9958758 0.60 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
IL17RC
interleukin 17 receptor C
chr20_+_31870927 0.60 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr19_+_4343691 0.60 ENST00000597036.1
MPND
MPN domain containing
chr12_+_6494285 0.60 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr11_+_695614 0.60 ENST00000608174.1
ENST00000397512.3
TMEM80
transmembrane protein 80
chr11_+_76494253 0.59 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr11_-_64052111 0.59 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chr19_+_531713 0.59 ENST00000215574.4
CDC34
cell division cycle 34
chr22_-_50689640 0.59 ENST00000448072.1
HDAC10
histone deacetylase 10
chr12_-_56122761 0.59 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63
CD63 molecule
chr22_-_23484246 0.58 ENST00000216036.4
RTDR1
rhabdoid tumor deletion region gene 1
chr12_-_125348448 0.58 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr17_-_40346477 0.58 ENST00000593209.1
ENST00000587427.1
ENST00000588352.1
ENST00000414034.3
ENST00000590249.1
GHDC
GH3 domain containing
chr20_+_62152077 0.57 ENST00000370179.3
ENST00000370177.1
PPDPF
pancreatic progenitor cell differentiation and proliferation factor
chr16_+_2570340 0.57 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr19_+_1491144 0.57 ENST00000233596.3
REEP6
receptor accessory protein 6
chr6_-_33160231 0.57 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr21_+_38338737 0.55 ENST00000430068.1
AP000704.5
AP000704.5
chr12_+_57849048 0.55 ENST00000266646.2
INHBE
inhibin, beta E
chr10_+_74870253 0.55 ENST00000544879.1
ENST00000537969.1
ENST00000372997.3
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr11_-_64901900 0.55 ENST00000526060.1
ENST00000307289.6
ENST00000528487.1
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr22_+_50312379 0.55 ENST00000407217.3
ENST00000403427.3
CRELD2
cysteine-rich with EGF-like domains 2
chr12_-_125348329 0.55 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
SCARB1
scavenger receptor class B, member 1
chr7_-_150777920 0.54 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr10_+_74870206 0.54 ENST00000357321.4
ENST00000349051.5
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr8_+_9009202 0.54 ENST00000518496.1
RP11-10A14.4
Uncharacterized protein
chr19_+_56152262 0.53 ENST00000325333.5
ENST00000590190.1
ZNF580
zinc finger protein 580
chr16_+_90089008 0.53 ENST00000268699.4
GAS8
growth arrest-specific 8
chr9_+_140119618 0.53 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chrX_+_152907913 0.53 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr19_+_45349630 0.53 ENST00000252483.5
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr19_+_4343584 0.52 ENST00000596722.1
MPND
MPN domain containing
chr10_-_14590644 0.51 ENST00000378470.1
FAM107B
family with sequence similarity 107, member B
chr2_-_74779744 0.51 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr19_-_45735138 0.50 ENST00000252482.3
EXOC3L2
exocyst complex component 3-like 2
chrX_-_153775760 0.50 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
G6PD
glucose-6-phosphate dehydrogenase
chr12_+_112451120 0.50 ENST00000261735.3
ENST00000455836.1
ERP29
endoplasmic reticulum protein 29
chr3_+_9958870 0.49 ENST00000413608.1
IL17RC
interleukin 17 receptor C
chr19_+_18283959 0.49 ENST00000597802.2
IFI30
interferon, gamma-inducible protein 30
chr8_-_145652336 0.48 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr22_-_50312052 0.48 ENST00000330817.6
ALG12
ALG12, alpha-1,6-mannosyltransferase
chr3_+_49057876 0.47 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr19_+_1438383 0.47 ENST00000586686.2
ENST00000591032.1
ENST00000586656.1
ENST00000589656.2
ENST00000593052.1
ENST00000586096.2
ENST00000591804.2
RPS15
ribosomal protein S15
chr14_+_23340822 0.47 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr3_-_122512619 0.47 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr17_-_8093471 0.46 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr19_+_18682531 0.46 ENST00000596304.1
ENST00000430157.2
UBA52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr4_-_860950 0.46 ENST00000511980.1
ENST00000510799.1
GAK
cyclin G associated kinase
chr19_-_5680231 0.46 ENST00000587950.1
C19orf70
chromosome 19 open reading frame 70
chr17_+_57784826 0.46 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr6_-_3457256 0.46 ENST00000436008.2
SLC22A23
solute carrier family 22, member 23
chr19_-_9896672 0.45 ENST00000589412.1
ENST00000586814.1
ZNF846
zinc finger protein 846
chr22_-_30162924 0.45 ENST00000344318.3
ENST00000397781.3
ZMAT5
zinc finger, matrin-type 5
chr6_-_33168391 0.44 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr11_+_47587129 0.44 ENST00000326656.8
ENST00000326674.9
PTPMT1
protein tyrosine phosphatase, mitochondrial 1
chr16_+_67022633 0.44 ENST00000398354.1
ENST00000326686.5
CES4A
carboxylesterase 4A
chr19_-_55836669 0.43 ENST00000326652.4
TMEM150B
transmembrane protein 150B
chr5_-_70272055 0.43 ENST00000514857.2
NAIP
NLR family, apoptosis inhibitory protein
chr6_+_83903061 0.43 ENST00000369724.4
ENST00000539997.1
RWDD2A
RWD domain containing 2A
chr19_-_55658281 0.43 ENST00000585321.2
ENST00000587465.2
TNNT1
troponin T type 1 (skeletal, slow)
chr17_-_7082668 0.43 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr9_-_35112376 0.42 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr14_-_24898731 0.42 ENST00000267406.6
CBLN3
cerebellin 3 precursor
chr17_-_42092313 0.42 ENST00000587529.1
ENST00000206380.3
ENST00000542039.1
TMEM101
transmembrane protein 101
chr11_-_65640071 0.41 ENST00000526624.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr19_+_42388437 0.41 ENST00000378152.4
ENST00000337665.4
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr19_-_5680202 0.41 ENST00000590389.1
C19orf70
chromosome 19 open reading frame 70
chr16_+_67022582 0.41 ENST00000541479.1
ENST00000338718.4
CES4A
carboxylesterase 4A
chr12_+_109915179 0.40 ENST00000434735.2
UBE3B
ubiquitin protein ligase E3B
chr3_+_8775466 0.40 ENST00000343849.2
ENST00000397368.2
CAV3
caveolin 3
chr7_+_150759634 0.40 ENST00000392826.2
ENST00000461735.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr8_+_37553261 0.40 ENST00000331569.4
ZNF703
zinc finger protein 703
chr8_+_145203548 0.40 ENST00000534366.1
MROH1
maestro heat-like repeat family member 1
chr21_+_47063590 0.40 ENST00000400314.1
PCBP3
poly(rC) binding protein 3
chr9_+_86238016 0.40 ENST00000530832.1
ENST00000405990.3
ENST00000376417.4
ENST00000376419.4
IDNK
idnK, gluconokinase homolog (E. coli)
chr9_-_139094988 0.39 ENST00000371746.3
LHX3
LIM homeobox 3
chr19_-_55836697 0.39 ENST00000438693.1
ENST00000591570.1
TMEM150B
transmembrane protein 150B
chr15_+_65204075 0.39 ENST00000380230.3
ENST00000357698.3
ENST00000395720.1
ENST00000496660.1
ENST00000319580.8
ANKDD1A
ankyrin repeat and death domain containing 1A
chr19_-_39368887 0.39 ENST00000340740.3
ENST00000591812.1
RINL
Ras and Rab interactor-like
chr6_-_43478239 0.39 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr20_-_3748363 0.39 ENST00000217195.8
C20orf27
chromosome 20 open reading frame 27
chr13_+_78315295 0.39 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr19_+_17970677 0.38 ENST00000222247.5
RPL18A
ribosomal protein L18a
chr19_-_17014408 0.38 ENST00000594249.1
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr8_-_143484483 0.38 ENST00000519651.1
ENST00000307180.3
ENST00000518720.1
ENST00000524325.1
TSNARE1
t-SNARE domain containing 1
chr11_+_117070904 0.38 ENST00000529792.1
TAGLN
transgelin
chr19_-_16653226 0.38 ENST00000198939.6
CHERP
calcium homeostasis endoplasmic reticulum protein
chr19_+_45681997 0.38 ENST00000433642.2
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3
chr7_-_75443118 0.38 ENST00000222902.2
CCL24
chemokine (C-C motif) ligand 24
chr21_-_43816052 0.38 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr11_-_62439727 0.37 ENST00000528862.1
C11orf48
chromosome 11 open reading frame 48
chr22_+_47070490 0.37 ENST00000408031.1
GRAMD4
GRAM domain containing 4
chr10_+_695888 0.36 ENST00000441152.2
PRR26
proline rich 26
chr21_-_33984865 0.36 ENST00000458138.1
C21orf59
chromosome 21 open reading frame 59
chr17_-_48450265 0.36 ENST00000507088.1
MRPL27
mitochondrial ribosomal protein L27
chr6_+_84563295 0.35 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chrX_+_153775821 0.35 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr8_-_27850180 0.35 ENST00000380385.2
ENST00000301906.4
ENST00000354914.3
SCARA5
scavenger receptor class A, member 5 (putative)
chr16_+_476379 0.34 ENST00000434585.1
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr5_-_180242534 0.34 ENST00000333055.3
ENST00000513431.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr20_-_3748416 0.34 ENST00000399672.1
C20orf27
chromosome 20 open reading frame 27
chr16_+_29817399 0.34 ENST00000545521.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr19_-_48894762 0.34 ENST00000600980.1
ENST00000330720.2
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr19_-_7697857 0.34 ENST00000598935.1
PCP2
Purkinje cell protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.0 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.8 2.5 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.6 1.9 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.4 1.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.3 1.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.3 1.0 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 2.9 GO:0046618 drug export(GO:0046618)
0.3 0.9 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 1.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.3 0.9 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.3 0.8 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.3 1.6 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.3 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.9 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2 1.4 GO:0070295 renal water absorption(GO:0070295)
0.2 2.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 0.9 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 0.6 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.2 0.9 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.2 0.7 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.2 0.9 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.2 0.7 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 1.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.2 0.5 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.2 1.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 3.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 1.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.6 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 1.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.5 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.6 GO:0060023 soft palate development(GO:0060023)
0.1 2.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.0 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.5 GO:0043335 protein unfolding(GO:0043335)
0.1 0.1 GO:2000410 regulation of thymocyte migration(GO:2000410)
0.1 1.7 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 2.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.4 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.7 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.1 GO:0097066 response to thyroid hormone(GO:0097066)
0.1 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.9 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.9 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 1.6 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 0.5 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 1.7 GO:0007620 copulation(GO:0007620)
0.1 0.6 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.4 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.7 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.1 GO:0035419 activation of MAPK activity involved in innate immune response(GO:0035419)
0.1 0.6 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.1 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 1.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.2 GO:1902824 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 1.5 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.2 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 2.0 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0016036 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.4 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.3 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.4 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 1.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 1.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 2.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.5 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.0 GO:0048320 axial mesoderm morphogenesis(GO:0048319) axial mesoderm formation(GO:0048320)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.1 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 1.8 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.0 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.5 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 1.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.5 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0060323 head morphogenesis(GO:0060323) face development(GO:0060324) face morphogenesis(GO:0060325)
0.0 0.1 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 1.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 5.0 GO:0034706 sodium channel complex(GO:0034706)
0.2 0.9 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.1 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 0.8 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 2.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.2 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.7 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 3.4 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 1.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 1.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.5 2.5 GO:0019770 IgG receptor activity(GO:0019770)
0.5 2.9 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.5 1.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 1.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.4 1.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.3 2.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.3 0.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.3 1.4 GO:0015254 glycerol channel activity(GO:0015254)
0.3 0.8 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.3 1.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 1.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.5 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 2.3 GO:0016803 ether hydrolase activity(GO:0016803)
0.2 0.5 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.2 0.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.4 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 3.1 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 1.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.8 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.3 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 5.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.3 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.9 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 1.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 2.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.1 0.2 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1 0.6 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.8 GO:0031014 troponin T binding(GO:0031014)
0.1 1.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.1 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.5 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 0.8 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.9 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.0 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 2.7 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 3.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 2.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.8 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane