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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRDM1

Z-value: 0.80

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Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
PRDM1
ENSG00000057657.10 PR/SET domain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM1hg19_v2_chr6_+_106546808_106546833-0.502.3e-02Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_67970990 1.59 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr6_+_127439749 1.54 ENST00000356698.4
RSPO3
R-spondin 3
chr18_+_3466248 1.49 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr17_+_41158742 1.48 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr5_+_92919043 1.46 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr20_+_388791 1.43 ENST00000441733.1
ENST00000353660.3
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr9_+_137533615 1.30 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr17_-_26695013 1.27 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr19_+_34287174 1.26 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr2_+_239756671 1.16 ENST00000448943.2
TWIST2
twist family bHLH transcription factor 2
chr22_-_30642782 1.15 ENST00000249075.3
LIF
leukemia inhibitory factor
chr20_+_388935 1.14 ENST00000382181.2
ENST00000400247.3
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr1_+_110453203 1.13 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr17_-_26694979 1.12 ENST00000438614.1
VTN
vitronectin
chr3_+_8543561 1.10 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr2_+_145780739 1.09 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr6_-_29527702 1.04 ENST00000377050.4
UBD
ubiquitin D
chr20_+_388679 0.99 ENST00000356286.5
ENST00000475269.1
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr6_+_32821924 0.99 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr2_+_145780767 0.95 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr19_+_34287751 0.91 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr7_+_134832808 0.90 ENST00000275767.3
TMEM140
transmembrane protein 140
chr3_+_8543393 0.89 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr2_+_234590556 0.80 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr6_-_41909191 0.80 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr1_+_110453514 0.77 ENST00000369802.3
ENST00000420111.2
CSF1
colony stimulating factor 1 (macrophage)
chr3_+_8543533 0.76 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr1_-_153919128 0.73 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr22_-_36635225 0.71 ENST00000529194.1
APOL2
apolipoprotein L, 2
chr14_-_69263043 0.65 ENST00000408913.2
ZFP36L1
ZFP36 ring finger protein-like 1
chr2_+_145780725 0.65 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chr14_-_24615523 0.63 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr20_-_5100591 0.62 ENST00000379143.5
PCNA
proliferating cell nuclear antigen
chr4_+_142557717 0.62 ENST00000320650.4
ENST00000296545.7
IL15
interleukin 15
chr2_-_145275228 0.60 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr1_+_164600184 0.60 ENST00000482110.1
PBX1
pre-B-cell leukemia homeobox 1
chr14_-_24615805 0.58 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr15_-_72565340 0.57 ENST00000568360.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr19_+_36239576 0.53 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr19_+_24009879 0.51 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr4_-_111558135 0.51 ENST00000394598.2
ENST00000394595.3
PITX2
paired-like homeodomain 2
chr15_+_85144217 0.50 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr1_+_110453608 0.50 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)
chr22_-_30642728 0.50 ENST00000403987.3
LIF
leukemia inhibitory factor
chr15_-_56209306 0.48 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr1_+_199996702 0.47 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr6_+_32811885 0.47 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr11_+_64008443 0.46 ENST00000309366.4
FKBP2
FK506 binding protein 2, 13kDa
chr1_+_207262881 0.46 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr11_-_72432950 0.43 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_-_44497118 0.42 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr6_+_105404899 0.42 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr11_-_796197 0.42 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr11_+_71709938 0.42 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
IL18BP
interleukin 18 binding protein
chr4_+_183065793 0.42 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr10_+_62538089 0.42 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr6_-_32811771 0.41 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr22_-_36635598 0.41 ENST00000454728.1
APOL2
apolipoprotein L, 2
chr16_-_88851618 0.40 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr12_+_94542459 0.40 ENST00000258526.4
PLXNC1
plexin C1
chr4_+_142558078 0.40 ENST00000529613.1
IL15
interleukin 15
chr9_-_117568365 0.39 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr1_+_110453109 0.39 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr22_-_36635563 0.39 ENST00000451256.2
APOL2
apolipoprotein L, 2
chr10_-_21661870 0.38 ENST00000433460.1
RP11-275N1.1
RP11-275N1.1
chr1_+_151372010 0.38 ENST00000290541.6
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr8_-_29120580 0.37 ENST00000524189.1
KIF13B
kinesin family member 13B
chr5_-_159766528 0.37 ENST00000505287.2
CCNJL
cyclin J-like
chr22_-_36635684 0.36 ENST00000358502.5
APOL2
apolipoprotein L, 2
chr7_-_86849025 0.36 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr1_+_110453462 0.35 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr15_+_75491213 0.35 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr8_+_77593448 0.34 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr10_+_62538248 0.34 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr2_-_145275828 0.33 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr16_+_84801852 0.32 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr8_+_9009202 0.31 ENST00000518496.1
RP11-10A14.4
Uncharacterized protein
chr11_+_64008525 0.31 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr17_-_43339474 0.31 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr7_-_47621229 0.31 ENST00000434451.1
TNS3
tensin 3
chr5_-_66942617 0.31 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr5_-_59481406 0.30 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_37393406 0.29 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr3_-_149375783 0.28 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr16_-_31085514 0.28 ENST00000300849.4
ZNF668
zinc finger protein 668
chr4_+_142557771 0.28 ENST00000514653.1
IL15
interleukin 15
chr11_-_47736896 0.28 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2
ATP/GTP binding protein-like 2
chr1_-_161014731 0.28 ENST00000368020.1
USF1
upstream transcription factor 1
chr11_-_28129656 0.28 ENST00000263181.6
KIF18A
kinesin family member 18A
chr7_-_86848933 0.27 ENST00000423734.1
TMEM243
transmembrane protein 243, mitochondrial
chrX_+_10124977 0.27 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr6_-_33282024 0.26 ENST00000475304.1
ENST00000489157.1
TAPBP
TAP binding protein (tapasin)
chr1_-_44497024 0.26 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr6_+_32811861 0.26 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr1_+_199996733 0.26 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr12_-_86650045 0.25 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr16_+_30675654 0.25 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr10_-_82049424 0.25 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr2_-_36779411 0.24 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr12_+_57916584 0.24 ENST00000546632.1
ENST00000549623.1
ENST00000431731.2
MBD6
methyl-CpG binding domain protein 6
chr2_+_234545092 0.24 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr1_-_244006528 0.23 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr3_-_114343039 0.23 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_76506706 0.22 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr7_-_111424462 0.22 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr7_-_111424506 0.22 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr12_-_120189900 0.20 ENST00000546026.1
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr11_+_64323428 0.19 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr12_-_86650077 0.19 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_-_37392086 0.19 ENST00000561208.1
MEIS2
Meis homeobox 2
chr1_+_2985760 0.19 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr8_-_23540402 0.19 ENST00000523261.1
ENST00000380871.4
NKX3-1
NK3 homeobox 1
chr9_+_18474098 0.19 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr9_+_67968793 0.18 ENST00000417488.1
RP11-195B21.3
Protein LOC644249
chr8_+_134203273 0.18 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr2_-_64246206 0.18 ENST00000409558.4
ENST00000272322.4
VPS54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr5_-_94417186 0.18 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_+_166150541 0.18 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr4_+_15376165 0.18 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr6_+_152011628 0.17 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr17_-_43339453 0.17 ENST00000543122.1
SPATA32
spermatogenesis associated 32
chr14_-_23479331 0.17 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
C14orf93
chromosome 14 open reading frame 93
chr8_+_39770803 0.17 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr1_-_151735937 0.17 ENST00000368829.3
ENST00000368830.3
MRPL9
mitochondrial ribosomal protein L9
chr5_-_94417314 0.17 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr6_+_106535455 0.16 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr3_+_69915363 0.16 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr9_+_18474163 0.16 ENST00000380566.4
ADAMTSL1
ADAMTS-like 1
chr12_+_9144626 0.16 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr14_+_24605361 0.16 ENST00000206451.6
ENST00000559123.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr13_+_24144796 0.16 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr11_+_64323156 0.16 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr2_-_142888573 0.15 ENST00000434794.1
LRP1B
low density lipoprotein receptor-related protein 1B
chr15_+_75491203 0.15 ENST00000562637.1
C15orf39
chromosome 15 open reading frame 39
chr12_+_43086018 0.15 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr2_+_145780662 0.15 ENST00000423031.1
TEX41
testis expressed 41 (non-protein coding)
chr18_+_18943554 0.15 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr9_-_69229650 0.15 ENST00000416428.1
CBWD6
COBW domain containing 6
chr11_+_71710973 0.15 ENST00000393707.4
IL18BP
interleukin 18 binding protein
chr2_-_70475586 0.14 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr6_-_28220002 0.14 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr13_+_24144509 0.14 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr3_-_64431146 0.14 ENST00000569824.1
ENST00000485770.1
PRICKLE2
RP11-14D22.2
prickle homolog 2 (Drosophila)
RP11-14D22.2
chr9_+_18474204 0.14 ENST00000276935.6
ADAMTSL1
ADAMTS-like 1
chr6_-_154831779 0.14 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr17_+_7465216 0.14 ENST00000321337.7
SENP3
SUMO1/sentrin/SMT3 specific peptidase 3
chr6_-_32806483 0.14 ENST00000374899.4
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_-_17186229 0.14 ENST00000253669.5
ENST00000448593.2
HAUS8
HAUS augmin-like complex, subunit 8
chr2_+_69240302 0.13 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chrX_-_133930285 0.13 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr11_+_46402482 0.12 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr11_+_71710648 0.11 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr8_+_77318769 0.11 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr2_+_69240415 0.11 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr2_+_234526272 0.11 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr17_-_56606705 0.11 ENST00000317268.3
SEPT4
septin 4
chr2_+_231280908 0.11 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr17_-_56606664 0.11 ENST00000580844.1
SEPT4
septin 4
chr3_+_51977294 0.11 ENST00000498510.1
PARP3
poly (ADP-ribose) polymerase family, member 3
chr4_+_147145709 0.10 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr17_-_56606639 0.10 ENST00000579371.1
SEPT4
septin 4
chr7_+_39125365 0.10 ENST00000559001.1
ENST00000464276.2
POU6F2
POU class 6 homeobox 2
chrX_+_123095860 0.09 ENST00000428941.1
STAG2
stromal antigen 2
chr16_+_20685815 0.09 ENST00000561584.1
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr10_-_131762105 0.09 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr12_-_57504975 0.09 ENST00000553397.1
ENST00000556259.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr13_-_33924755 0.09 ENST00000439831.1
ENST00000567873.1
STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_+_47422485 0.09 ENST00000431726.1
ENST00000456221.1
ENST00000265562.4
PTPN23
protein tyrosine phosphatase, non-receptor type 23
chr6_-_44400720 0.08 ENST00000595057.1
AL133262.1
AL133262.1
chr6_-_33281979 0.08 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr14_+_24605389 0.08 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr12_-_71003568 0.08 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_+_17906970 0.08 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_57182400 0.08 ENST00000607273.1
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr6_+_146348810 0.07 ENST00000492807.2
GRM1
glutamate receptor, metabotropic 1
chr12_-_57505121 0.07 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr20_+_30946106 0.07 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chrX_+_123095890 0.07 ENST00000435215.1
STAG2
stromal antigen 2
chr16_+_31085714 0.07 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr6_+_146348782 0.07 ENST00000361719.2
ENST00000392299.2
GRM1
glutamate receptor, metabotropic 1
chr20_-_18774614 0.06 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr21_+_22370608 0.06 ENST00000400546.1
NCAM2
neural cell adhesion molecule 2
chr6_-_32806506 0.06 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr15_+_71184931 0.06 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr1_-_217250231 0.06 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr4_-_100140331 0.05 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr8_+_77593474 0.05 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr17_+_7211656 0.05 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr10_-_35104185 0.05 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr6_+_118869452 0.05 ENST00000357525.5
PLN
phospholamban
chr11_+_60609537 0.05 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr13_+_108921977 0.05 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr3_+_69915385 0.05 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr11_-_40315640 0.04 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr13_+_108922228 0.04 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr13_-_95364389 0.04 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr6_-_9933500 0.04 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr20_+_6748311 0.03 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr7_-_37488547 0.03 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr2_+_231280954 0.03 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.3 GO:0045062 extrathymic T cell selection(GO:0045062)
0.4 3.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 1.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.7 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 0.6 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.4 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.8 GO:0009804 coumarin metabolic process(GO:0009804)
0.1 0.8 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 0.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.5 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.1 2.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.5 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.4 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 1.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.2 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 5.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.2 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.3 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.4 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.2 GO:2000836 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1903557 positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.0 1.9 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.7 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.0 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.3 GO:0001942 hair follicle development(GO:0001942) skin epidermis development(GO:0098773)
0.0 1.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0071797 LUBAC complex(GO:0071797)
0.4 3.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.4 3.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 1.5 GO:0008537 proteasome activator complex(GO:0008537)
0.2 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 0.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.4 3.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 0.7 GO:0042007 interleukin-18 binding(GO:0042007)
0.2 0.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 1.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.6 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 1.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 3.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 1.9 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 1.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 1.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.0 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 3.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 ST GAQ PATHWAY G alpha q Pathway
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 0.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 3.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling