Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for PRDM4

Z-value: 0.54

Motif logo

logo of

Transcription factors associated with PRDM4

Gene Symbol Gene ID Gene Info
PRDM4
ENSG00000110851.7 PR/SET domain 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154925_108154945-0.512.1e-02Click!

Activity profile of PRDM4 motif

Sorted Z-values of PRDM4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_42634844 3.42 ENST00000315323.3
FZD2
frizzled family receptor 2
chr2_+_233734994 3.39 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr14_+_105953246 3.36 ENST00000392531.3
CRIP1
cysteine-rich protein 1 (intestinal)
chr14_+_105953204 3.30 ENST00000409393.2
CRIP1
cysteine-rich protein 1 (intestinal)
chr2_+_234296792 1.70 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr12_+_104682496 1.40 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr11_-_85393886 1.36 ENST00000534224.1
CREBZF
CREB/ATF bZIP transcription factor
chr5_+_159343688 1.08 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr15_+_66797627 1.07 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr5_-_78281623 0.83 ENST00000521117.1
ARSB
arylsulfatase B
chr9_+_139560197 0.81 ENST00000371698.3
EGFL7
EGF-like-domain, multiple 7
chr12_+_104682667 0.77 ENST00000527335.1
TXNRD1
thioredoxin reductase 1
chr2_+_219264466 0.74 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr20_+_62697564 0.72 ENST00000458442.1
TCEA2
transcription elongation factor A (SII), 2
chr20_-_49639631 0.67 ENST00000424171.1
ENST00000439216.1
ENST00000371571.4
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr12_-_58240470 0.66 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr19_+_41117770 0.62 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr19_-_11639910 0.62 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr2_-_179343226 0.57 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr22_+_38864041 0.56 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr19_-_11639931 0.53 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr11_+_8040739 0.52 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr9_-_16727978 0.50 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr11_+_47279504 0.50 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr5_-_78281603 0.49 ENST00000264914.4
ARSB
arylsulfatase B
chr6_+_26045603 0.45 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr16_+_29823427 0.44 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2
proline-rich transmembrane protein 2
chr2_-_179343268 0.43 ENST00000424785.2
FKBP7
FK506 binding protein 7
chr5_+_140261703 0.39 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr5_-_78281775 0.36 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr14_+_24025194 0.36 ENST00000404535.3
ENST00000288014.6
THTPA
thiamine triphosphatase
chr20_-_49639612 0.36 ENST00000396017.3
ENST00000433903.1
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr4_+_667307 0.35 ENST00000506838.1
MYL5
myosin, light chain 5, regulatory
chr15_-_66797172 0.34 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4
ribosomal protein L4
chr6_-_24721054 0.34 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr12_+_69979446 0.33 ENST00000543146.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr1_+_27113963 0.31 ENST00000430292.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr2_+_219264762 0.29 ENST00000452977.1
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr11_+_19138670 0.29 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr16_+_29823552 0.28 ENST00000300797.6
PRRT2
proline-rich transmembrane protein 2
chr1_-_43232649 0.27 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr5_+_102455968 0.27 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr5_+_102455853 0.27 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr19_+_42724423 0.25 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr1_+_27114418 0.25 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr1_+_27114589 0.23 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr5_+_80256453 0.21 ENST00000265080.4
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr5_-_34916871 0.20 ENST00000382038.2
RAD1
RAD1 homolog (S. pombe)
chr10_+_123923105 0.19 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr19_-_35264089 0.19 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
ZNF599
zinc finger protein 599
chr1_+_171750776 0.19 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13
methyltransferase like 13
chr14_+_24025345 0.19 ENST00000557630.1
THTPA
thiamine triphosphatase
chr10_-_105212141 0.16 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr1_-_161168834 0.15 ENST00000367995.3
ENST00000367996.5
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr12_+_15475462 0.15 ENST00000543886.1
ENST00000348962.2
PTPRO
protein tyrosine phosphatase, receptor type, O
chr11_-_40314652 0.14 ENST00000527150.1
LRRC4C
leucine rich repeat containing 4C
chr19_+_50180317 0.14 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr9_+_17135016 0.14 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr9_+_96338647 0.13 ENST00000359246.4
PHF2
PHD finger protein 2
chr3_+_16926441 0.12 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr8_+_94712732 0.12 ENST00000518322.1
FAM92A1
family with sequence similarity 92, member A1
chr1_+_222910625 0.11 ENST00000360827.2
FAM177B
family with sequence similarity 177, member B
chr4_-_83295103 0.11 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr17_-_9929581 0.09 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr16_+_29674540 0.09 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr8_+_91952750 0.08 ENST00000521366.1
NECAB1
N-terminal EF-hand calcium binding protein 1
chr5_-_180688105 0.07 ENST00000327767.4
TRIM52
tripartite motif containing 52
chr12_+_15475331 0.06 ENST00000281171.4
PTPRO
protein tyrosine phosphatase, receptor type, O
chr20_+_30555805 0.05 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr2_-_151905288 0.05 ENST00000409243.1
AC023469.1
HCG1817310; Uncharacterized protein
chr1_-_68516393 0.04 ENST00000395201.1
DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr16_+_15068916 0.03 ENST00000455313.2
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr3_+_148709128 0.03 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
GYG1
glycogenin 1
chr4_-_83295296 0.01 ENST00000507010.1
ENST00000503822.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.6 1.7 GO:0061580 colon epithelial cell migration(GO:0061580)
0.4 1.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.3 3.3 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.2 2.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.5 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.3 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.7 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.0 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.5 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.7 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1990423 RZZ complex(GO:1990423)
0.1 0.8 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 3.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 1.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.4 1.7 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.3 6.8 GO:0003680 AT DNA binding(GO:0003680)
0.3 0.8 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.2 1.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.2 0.5 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 1.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 3.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 3.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)