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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRRX1_ALX4_PHOX2A

Z-value: 0.41

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Transcription factors associated with PRRX1_ALX4_PHOX2A

Gene Symbol Gene ID Gene Info
PRRX1
ENSG00000116132.7 paired related homeobox 1
ALX4
ENSG00000052850.5 ALX homeobox 4
PHOX2A
ENSG00000165462.5 paired like homeobox 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX4hg19_v2_chr11_-_44331679_443317160.671.2e-03Click!
PRRX1hg19_v2_chr1_+_170632250_1706322770.272.6e-01Click!

Activity profile of PRRX1_ALX4_PHOX2A motif

Sorted Z-values of PRRX1_ALX4_PHOX2A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_155484155 1.11 ENST00000509493.1
FGB
fibrinogen beta chain
chr6_-_32908792 0.97 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr4_+_155484103 0.87 ENST00000302068.4
FGB
fibrinogen beta chain
chr3_+_159943362 0.77 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr6_-_107235331 0.67 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr4_+_76649753 0.66 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr8_-_95229531 0.60 ENST00000450165.2
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr6_-_76072719 0.60 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr2_+_152214098 0.59 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_228678550 0.51 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr6_-_32908765 0.47 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr14_-_95236551 0.41 ENST00000238558.3
GSC
goosecoid homeobox
chr6_-_107235378 0.41 ENST00000606430.1
RP1-60O19.1
RP1-60O19.1
chr17_+_61151306 0.40 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_-_145275228 0.38 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr6_-_107235287 0.38 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr18_+_20714525 0.37 ENST00000400473.2
CABLES1
Cdk5 and Abl enzyme substrate 1
chr4_+_48485341 0.36 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr6_+_3259122 0.36 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr8_+_86999516 0.35 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr3_-_157824292 0.34 ENST00000483851.2
SHOX2
short stature homeobox 2
chr11_+_1295809 0.33 ENST00000598274.1
AC136297.1
Uncharacterized protein
chr7_-_111032971 0.32 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_+_58003935 0.30 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr3_+_149192475 0.30 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr12_-_15815626 0.29 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr19_-_11456905 0.27 ENST00000588560.1
ENST00000592952.1
TMEM205
transmembrane protein 205
chr5_+_140514782 0.27 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr3_+_149191723 0.26 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr14_-_101036119 0.25 ENST00000355173.2
BEGAIN
brain-enriched guanylate kinase-associated
chr7_-_55620433 0.25 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr5_+_142149955 0.25 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr2_-_145275828 0.24 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr22_-_30642728 0.24 ENST00000403987.3
LIF
leukemia inhibitory factor
chr14_+_95078714 0.24 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_118796971 0.24 ENST00000542902.1
TAOK3
TAO kinase 3
chr2_-_145188137 0.23 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr2_-_58468437 0.23 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr15_+_75628232 0.23 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr2_+_176994408 0.22 ENST00000429017.1
ENST00000313173.4
ENST00000544999.1
HOXD8
homeobox D8
chr10_+_89420706 0.22 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr6_+_26087646 0.22 ENST00000309234.6
HFE
hemochromatosis
chr12_-_8088871 0.22 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr17_+_74463650 0.22 ENST00000392492.3
AANAT
aralkylamine N-acetyltransferase
chr4_+_74606223 0.22 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr15_+_75628394 0.21 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr19_-_11456872 0.21 ENST00000586218.1
TMEM205
transmembrane protein 205
chrX_-_55208866 0.21 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr12_+_54410664 0.21 ENST00000303406.4
HOXC4
homeobox C4
chr2_-_145278475 0.20 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_133562095 0.20 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr8_-_17752996 0.20 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr16_+_89334512 0.20 ENST00000602042.1
AC137932.1
AC137932.1
chr1_+_186798073 0.20 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr8_-_17752912 0.19 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chr1_+_170632250 0.19 ENST00000367760.3
PRRX1
paired related homeobox 1
chr7_-_107883678 0.19 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr2_+_74685413 0.19 ENST00000233615.2
WBP1
WW domain binding protein 1
chr8_-_122653630 0.19 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr7_+_30589829 0.18 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr4_-_76649546 0.18 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr19_-_11456935 0.18 ENST00000590788.1
ENST00000586590.1
ENST00000589555.1
ENST00000586956.1
ENST00000593256.2
ENST00000447337.1
ENST00000591677.1
ENST00000586701.1
ENST00000589655.1
TMEM205
RAB3D
transmembrane protein 205
RAB3D, member RAS oncogene family
chr3_-_11623804 0.18 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr19_-_11456722 0.18 ENST00000354882.5
TMEM205
transmembrane protein 205
chr14_-_57197224 0.17 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr1_+_244214577 0.17 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr15_-_26874230 0.17 ENST00000400188.3
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_+_20963632 0.17 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr19_+_50016610 0.16 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr12_+_20968608 0.16 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr14_+_65453432 0.16 ENST00000246166.2
FNTB
farnesyltransferase, CAAX box, beta
chr5_+_36606700 0.16 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_124741451 0.15 ENST00000520519.1
ANXA13
annexin A13
chr14_-_75536182 0.15 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr5_-_111093759 0.14 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr8_+_107738343 0.14 ENST00000521592.1
OXR1
oxidation resistance 1
chr12_-_118796910 0.14 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr6_+_3259148 0.14 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr22_-_43398442 0.13 ENST00000422336.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr2_-_114461655 0.13 ENST00000424612.1
AC017074.2
AC017074.2
chr12_+_20963647 0.12 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr5_-_54529415 0.12 ENST00000282572.4
CCNO
cyclin O
chr7_+_23338819 0.12 ENST00000466681.1
MALSU1
mitochondrial assembly of ribosomal large subunit 1
chr11_-_58035732 0.12 ENST00000395079.2
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr2_-_175711133 0.11 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr19_+_6887571 0.11 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr1_+_42846443 0.11 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr14_-_81425828 0.11 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr15_+_80733570 0.11 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr5_+_142149932 0.11 ENST00000274498.4
ARHGAP26
Rho GTPase activating protein 26
chr3_+_111393501 0.10 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_81106951 0.10 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chrX_+_119737806 0.10 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr12_-_10324716 0.10 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chrX_-_124097620 0.10 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr12_+_54519842 0.10 ENST00000508564.1
RP11-834C11.4
RP11-834C11.4
chrX_-_15332665 0.10 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr4_+_88571429 0.10 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr4_-_68829226 0.10 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr17_+_48556158 0.10 ENST00000258955.2
RSAD1
radical S-adenosyl methionine domain containing 1
chr1_+_183774240 0.10 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_-_68829144 0.10 ENST00000508048.1
TMPRSS11A
transmembrane protease, serine 11A
chr17_+_53342311 0.10 ENST00000226067.5
HLF
hepatic leukemia factor
chr8_-_102803163 0.09 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr19_+_13842559 0.09 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr4_+_169575875 0.09 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr12_+_49621658 0.09 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr7_-_93520191 0.09 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr7_+_93535866 0.09 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr4_+_183370146 0.09 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr15_-_34331243 0.09 ENST00000306730.3
AVEN
apoptosis, caspase activation inhibitor
chr19_+_34855925 0.09 ENST00000590375.1
ENST00000356487.5
GPI
glucose-6-phosphate isomerase
chr12_-_23737534 0.09 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr9_+_34652164 0.09 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr12_+_72080253 0.09 ENST00000549735.1
TMEM19
transmembrane protein 19
chr5_-_70272055 0.09 ENST00000514857.2
NAIP
NLR family, apoptosis inhibitory protein
chr3_-_27764190 0.09 ENST00000537516.1
EOMES
eomesodermin
chr10_+_97709725 0.08 ENST00000472454.2
RP11-248J23.6
Protein LOC100652732
chr10_+_67330096 0.08 ENST00000433152.4
ENST00000601979.1
ENST00000599409.1
ENST00000608678.1
RP11-222A11.1
RP11-222A11.1
chr7_-_117512264 0.08 ENST00000454375.1
CTTNBP2
cortactin binding protein 2
chr10_+_90672113 0.08 ENST00000371922.1
STAMBPL1
STAM binding protein-like 1
chr1_-_151148442 0.08 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr1_+_170115142 0.08 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr5_-_59783882 0.08 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_86253888 0.08 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr3_-_149293990 0.08 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr1_+_12976450 0.08 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr11_-_40315640 0.08 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr19_+_34855874 0.08 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr20_-_43133491 0.08 ENST00000411544.1
SERINC3
serine incorporator 3
chr16_+_21244986 0.08 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr15_-_65407524 0.08 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr3_+_69985792 0.08 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr14_+_24099318 0.08 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chr9_-_95298254 0.08 ENST00000444490.2
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr9_-_123639445 0.08 ENST00000312189.6
PHF19
PHD finger protein 19
chr14_-_21567009 0.07 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr2_+_223725723 0.07 ENST00000535678.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr11_+_8040739 0.07 ENST00000534099.1
TUB
tubby bipartite transcription factor
chrX_+_149887090 0.07 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr12_-_16761007 0.07 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_50459990 0.07 ENST00000448346.1
AL645730.2
AL645730.2
chr1_-_234667504 0.07 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr11_+_85359002 0.07 ENST00000528105.1
ENST00000304511.2
TMEM126A
transmembrane protein 126A
chr13_+_88325498 0.07 ENST00000400028.3
SLITRK5
SLIT and NTRK-like family, member 5
chr2_-_145277882 0.07 ENST00000465070.1
ENST00000444559.1
ZEB2
zinc finger E-box binding homeobox 2
chr3_-_156878482 0.07 ENST00000295925.4
CCNL1
cyclin L1
chr17_-_39150385 0.07 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr12_+_1099675 0.07 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr2_-_69180012 0.07 ENST00000481498.1
GKN2
gastrokine 2
chr1_+_186265399 0.07 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr2_+_29001711 0.07 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr9_-_123639600 0.07 ENST00000373896.3
PHF19
PHD finger protein 19
chr12_+_8666126 0.07 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr2_+_128458514 0.07 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr12_-_91573132 0.07 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr22_-_30953587 0.07 ENST00000453479.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr8_-_80942061 0.06 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr9_-_123639304 0.06 ENST00000436309.1
PHF19
PHD finger protein 19
chr13_-_81801115 0.06 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr5_+_40909354 0.06 ENST00000313164.9
C7
complement component 7
chr17_-_38911580 0.06 ENST00000312150.4
KRT25
keratin 25
chr1_+_15668240 0.06 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr12_-_7656357 0.06 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163
CD163 molecule
chr3_+_12329397 0.06 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr5_-_59481406 0.06 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_93535817 0.06 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr2_+_101437487 0.06 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr13_-_47471155 0.06 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr15_+_51669513 0.06 ENST00000558426.1
GLDN
gliomedin
chr4_-_174320687 0.06 ENST00000296506.3
SCRG1
stimulator of chondrogenesis 1
chr1_-_241799232 0.06 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr14_+_96722539 0.06 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr12_-_92539614 0.06 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr12_-_91573249 0.06 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr3_-_87325612 0.06 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1
POU class 1 homeobox 1
chr2_-_183291741 0.06 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr3_+_69985734 0.06 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr5_-_111312622 0.06 ENST00000395634.3
NREP
neuronal regeneration related protein
chr18_-_52989217 0.06 ENST00000570287.2
TCF4
transcription factor 4
chr4_-_89951028 0.06 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr17_-_39023462 0.06 ENST00000251643.4
KRT12
keratin 12
chr14_+_38264418 0.06 ENST00000267368.7
ENST00000382320.3
TTC6
tetratricopeptide repeat domain 6
chr17_+_7155819 0.06 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
ELP5
elongator acetyltransferase complex subunit 5
chr9_-_70465758 0.06 ENST00000489273.1
CBWD5
COBW domain containing 5
chr1_-_200379180 0.06 ENST00000294740.3
ZNF281
zinc finger protein 281
chr1_+_154401791 0.06 ENST00000476006.1
IL6R
interleukin 6 receptor
chr4_-_100356551 0.06 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_+_22694123 0.06 ENST00000534801.1
GAS2
growth arrest-specific 2
chrX_+_9431324 0.06 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr8_-_121457608 0.05 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr1_+_180199393 0.05 ENST00000263726.2
LHX4
LIM homeobox 4
chr14_-_83262540 0.05 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chr9_-_95244781 0.05 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr19_-_44174330 0.05 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr4_-_103940791 0.05 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
SLC9B1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr1_+_149239529 0.05 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr12_-_56321397 0.05 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr5_+_137722255 0.05 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr6_+_44187242 0.05 ENST00000393844.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PRRX1_ALX4_PHOX2A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2 0.5 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 2.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.6 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.0 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2 0.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.2 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.0 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 2.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines