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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RARB

Z-value: 0.45

Motif logo

Transcription factors associated with RARB

Gene Symbol Gene ID Gene Info
ENSG00000077092.14 retinoic acid receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARBhg19_v2_chr3_+_25469724_254697730.861.1e-06Click!

Activity profile of RARB motif

Sorted Z-values of RARB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_46649905 0.97 ENST00000569702.1
SHC SH2-domain binding protein 1
chr17_-_41277370 0.89 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
breast cancer 1, early onset
chr6_+_49431073 0.76 ENST00000335783.3
centromere protein Q
chr9_+_104296163 0.73 ENST00000374819.2
ENST00000479306.1
ring finger protein 20, E3 ubiquitin protein ligase
chr17_-_41277317 0.71 ENST00000497488.1
ENST00000489037.1
ENST00000470026.1
ENST00000586385.1
ENST00000591534.1
ENST00000591849.1
breast cancer 1, early onset
chrX_-_119709637 0.58 ENST00000404115.3
cullin 4B
chr17_+_78518617 0.57 ENST00000537330.1
ENST00000570891.1
regulatory associated protein of MTOR, complex 1
chr1_+_28836561 0.57 ENST00000419074.1
regulator of chromosome condensation 1
chr14_-_39572345 0.56 ENST00000548032.2
ENST00000556092.1
ENST00000557280.1
ENST00000545328.2
ENST00000553970.1
Sec23 homolog A (S. cerevisiae)
chr9_+_104296243 0.56 ENST00000466817.1
ring finger protein 20, E3 ubiquitin protein ligase
chr15_+_29211570 0.56 ENST00000558804.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr22_-_43398442 0.55 ENST00000422336.1
protein kinase C and casein kinase substrate in neurons 2
chr18_-_74839891 0.55 ENST00000581878.1
myelin basic protein
chr11_+_125461607 0.51 ENST00000527606.1
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chrX_+_102024075 0.51 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
long intergenic non-protein coding RNA 630
chr18_+_657578 0.51 ENST00000323274.10
thymidylate synthetase
chr1_-_23520755 0.49 ENST00000314113.3
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr9_+_131217459 0.44 ENST00000497812.2
ENST00000393533.2
outer dense fiber of sperm tails 2
chr4_-_6557336 0.44 ENST00000507294.1
protein phosphatase 2, regulatory subunit B, gamma
chr9_+_67977438 0.44 ENST00000456982.1
Protein LOC644249
chr8_-_95274536 0.44 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr17_-_79533608 0.43 ENST00000572760.1
ENST00000573876.1
nuclear protein localization 4 homolog (S. cerevisiae)
chr11_-_122931881 0.42 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr12_+_49658855 0.42 ENST00000549183.1
tubulin, alpha 1c
chr13_+_73302047 0.41 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
bora, aurora kinase A activator
chr6_-_49430886 0.41 ENST00000274813.3
methylmalonyl CoA mutase
chr10_-_81203972 0.41 ENST00000372333.3
zinc finger, CCHC domain containing 24
chr1_+_35544968 0.41 ENST00000359858.4
ENST00000373330.1
zinc finger, MYM-type 1
chr12_+_57854274 0.41 ENST00000528432.1
GLI family zinc finger 1
chr1_-_53019059 0.40 ENST00000484723.2
ENST00000524582.1
zinc finger, CCHC domain containing 11
chr3_-_121448791 0.39 ENST00000489400.1
golgin B1
chr12_-_120241187 0.39 ENST00000392520.2
citron (rho-interacting, serine/threonine kinase 21)
chr9_+_104296122 0.38 ENST00000389120.3
ring finger protein 20, E3 ubiquitin protein ligase
chr11_+_121447469 0.37 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr10_-_33625154 0.36 ENST00000265371.4
neuropilin 1
chr10_-_65028817 0.36 ENST00000542921.1
jumonji domain containing 1C
chr8_+_48873453 0.34 ENST00000523944.1
minichromosome maintenance complex component 4
chr5_-_141392538 0.34 ENST00000503794.1
ENST00000510194.1
ENST00000504424.1
ENST00000513454.1
ENST00000458112.2
ENST00000542860.1
ENST00000503229.1
ENST00000500692.2
ENST00000311337.6
ENST00000504139.1
ENST00000505689.1
glucosamine-6-phosphate deaminase 1
chrX_+_23682379 0.32 ENST00000379349.1
peroxiredoxin 4
chr4_+_128802016 0.31 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
polo-like kinase 4
chr10_-_65028938 0.31 ENST00000402544.1
jumonji domain containing 1C
chr3_+_99986036 0.31 ENST00000471098.1
TBC1 domain family, member 23
chr5_-_74162605 0.31 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
family with sequence similarity 169, member A
chr3_+_127317066 0.30 ENST00000265056.7
minichromosome maintenance complex component 2
chr17_-_79900255 0.30 ENST00000330655.3
ENST00000582198.1
myeloid-associated differentiation marker-like 2
pyrroline-5-carboxylate reductase 1
chrX_+_123095890 0.30 ENST00000435215.1
stromal antigen 2
chr1_+_78245303 0.29 ENST00000370791.3
ENST00000443751.2
family with sequence similarity 73, member A
chr14_+_89290965 0.29 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
tetratricopeptide repeat domain 8
chr11_+_95523621 0.28 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr12_+_93963590 0.28 ENST00000340600.2
suppressor of cytokine signaling 2
chr17_+_8316442 0.28 ENST00000582812.1
nudE neurodevelopment protein 1-like 1
chr21_-_35284635 0.27 ENST00000429238.1
AP000304.12
chr17_-_28619059 0.27 ENST00000580709.1
bleomycin hydrolase
chr11_-_63381823 0.27 ENST00000323646.5
phospholipase A2, group XVI
chr7_-_107204706 0.27 ENST00000393603.2
component of oligomeric golgi complex 5
chr8_-_141774467 0.27 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr1_-_23521222 0.26 ENST00000374619.1
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr14_-_80697396 0.26 ENST00000557010.1
deiodinase, iodothyronine, type II
chr12_-_112443767 0.26 ENST00000550233.1
ENST00000546962.1
ENST00000550800.2
transmembrane protein 116
chr12_-_112443830 0.25 ENST00000550037.1
ENST00000549425.1
transmembrane protein 116
chr2_+_29117509 0.25 ENST00000407426.3
WD repeat domain 43
chr9_-_125590818 0.25 ENST00000259467.4
phosducin-like
chr16_+_68877496 0.24 ENST00000261778.1
transport and golgi organization 6 homolog (Drosophila)
chr5_+_70883154 0.24 ENST00000509358.2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr8_+_8860314 0.24 ENST00000250263.7
ENST00000519292.1
exoribonuclease 1
chr10_+_6779326 0.24 ENST00000417112.1
RP11-554I8.2
chr9_-_104145795 0.24 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr5_+_27472371 0.24 ENST00000512067.1
ENST00000510165.1
ENST00000505775.1
ENST00000514844.1
ENST00000503107.1
long intergenic non-protein coding RNA 1021
chr7_-_98805129 0.23 ENST00000327442.6
karyopherin alpha 7 (importin alpha 8)
chr4_+_56719782 0.23 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
exocyst complex component 1
chr8_-_23315131 0.22 ENST00000518718.1
ectonucleoside triphosphate diphosphohydrolase 4
chr2_-_25194476 0.22 ENST00000534855.1
DnaJ (Hsp40) homolog, subfamily C, member 27
chr19_+_13228917 0.22 ENST00000586171.1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr5_-_74162739 0.21 ENST00000513277.1
family with sequence similarity 169, member A
chr2_-_175499294 0.21 ENST00000392547.2
WAS/WASL interacting protein family, member 1
chr11_-_63381925 0.21 ENST00000415826.1
phospholipase A2, group XVI
chr1_+_66258846 0.21 ENST00000341517.4
phosphodiesterase 4B, cAMP-specific
chrX_+_123095860 0.21 ENST00000428941.1
stromal antigen 2
chr1_-_224624730 0.20 ENST00000445239.1
WD repeat domain 26
chr20_+_43990576 0.20 ENST00000372727.1
ENST00000414310.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr4_-_141075330 0.20 ENST00000509479.2
mastermind-like 3 (Drosophila)
chr2_-_3521518 0.20 ENST00000382093.5
acireductone dioxygenase 1
chr7_-_107204918 0.19 ENST00000297135.3
component of oligomeric golgi complex 5
chr2_-_107084826 0.19 ENST00000304514.7
ENST00000409886.3
RANBP2-like and GRIP domain containing 3
chr17_-_46178527 0.19 ENST00000393408.3
chromobox homolog 1
chr15_-_54051831 0.19 ENST00000557913.1
ENST00000360509.5
WD repeat domain 72
chr1_+_160175166 0.19 ENST00000368077.1
phosphoprotein enriched in astrocytes 15
chr16_-_69390209 0.19 ENST00000563634.1
Uncharacterized protein
chr13_-_30881134 0.19 ENST00000380617.3
ENST00000441394.1
katanin p60 subunit A-like 1
chr11_+_65029233 0.18 ENST00000265465.3
polymerase (DNA directed), alpha 2, accessory subunit
chr17_-_46178741 0.18 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr12_+_104682496 0.18 ENST00000378070.4
thioredoxin reductase 1
chr6_+_24495067 0.18 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr6_+_2988199 0.18 ENST00000450238.1
ENST00000445000.1
ENST00000426637.1
long intergenic non-protein coding RNA 1011
NAD(P)H dehydrogenase, quinone 2
chr14_+_62164340 0.18 ENST00000557538.1
ENST00000539097.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr10_-_27389320 0.18 ENST00000436985.2
ankyrin repeat domain 26
chr6_+_76311636 0.18 ENST00000327284.8
SUMO1/sentrin specific peptidase 6
chr12_-_109221160 0.18 ENST00000326470.5
slingshot protein phosphatase 1
chr2_-_176866978 0.18 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr13_+_111893533 0.17 ENST00000478679.1
Rho guanine nucleotide exchange factor (GEF) 7
chr12_-_323689 0.17 ENST00000428720.1
solute carrier family 6 (neurotransmitter transporter), member 12
chr10_+_11784360 0.17 ENST00000379215.4
ENST00000420401.1
enoyl CoA hydratase domain containing 3
chr18_-_21852143 0.17 ENST00000399443.3
oxysterol binding protein-like 1A
chr2_-_208031542 0.17 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr1_-_111506562 0.17 ENST00000485275.2
ENST00000369763.4
ligand dependent nuclear receptor interacting factor 1
chr16_+_57673207 0.16 ENST00000564783.1
ENST00000564729.1
ENST00000565976.1
ENST00000566508.1
ENST00000544297.1
G protein-coupled receptor 56
chr6_+_147527103 0.16 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr1_+_26872324 0.16 ENST00000531382.1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr5_+_446253 0.16 ENST00000315013.5
exocyst complex component 3
chr11_-_129817471 0.16 ENST00000423662.2
PR domain containing 10
chr16_+_2106134 0.15 ENST00000467949.1
tuberous sclerosis 2
chr1_+_53392901 0.15 ENST00000371514.3
ENST00000528311.1
ENST00000371509.4
ENST00000407246.2
ENST00000371513.5
sterol carrier protein 2
chr2_-_3606206 0.15 ENST00000315212.3
ribonuclease H1
chr16_+_2533020 0.15 ENST00000562105.1
TBC1 domain family, member 24
chr12_+_56075330 0.15 ENST00000394252.3
methyltransferase like 7B
chr12_+_113796347 0.15 ENST00000545182.2
ENST00000280800.3
phospholipase B domain containing 2
chr17_+_13972807 0.14 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
cytochrome c oxidase assembly homolog 10 (yeast)
chr1_+_52521957 0.14 ENST00000472944.2
ENST00000484036.1
basic transcription factor 3-like 4
chr2_+_88991162 0.14 ENST00000283646.4
ribose 5-phosphate isomerase A
chr1_-_150693318 0.14 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMA domain containing 1
chr10_-_29923893 0.14 ENST00000355867.4
supervillin
chr10_-_27530997 0.14 ENST00000375901.1
ENST00000412279.1
ENST00000375905.4
acyl-CoA binding domain containing 5
chr2_+_108443388 0.13 ENST00000354986.4
ENST00000408999.3
RANBP2-like and GRIP domain containing 4
chr2_-_97405775 0.13 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
lectin, mannose-binding 2-like
chr6_-_31763408 0.13 ENST00000444930.2
valyl-tRNA synthetase
chr19_+_38880695 0.13 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr8_-_27462822 0.13 ENST00000522098.1
clusterin
chr1_-_160313025 0.13 ENST00000368069.3
ENST00000241704.7
coatomer protein complex, subunit alpha
chr1_-_109618566 0.13 ENST00000338366.5
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr18_-_19283649 0.12 ENST00000584464.1
ENST00000578270.1
abhydrolase domain containing 3
chr5_+_147774275 0.12 ENST00000513826.1
F-box protein 38
chr1_+_150898733 0.12 ENST00000525956.1
SET domain, bifurcated 1
chr6_+_31554612 0.12 ENST00000211921.7
leukocyte specific transcript 1
chr7_-_6098770 0.12 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr20_+_33462745 0.12 ENST00000488172.1
acyl-CoA synthetase short-chain family member 2
chr16_+_15596123 0.12 ENST00000452191.2
chromosome 16 open reading frame 45
chr12_-_52761262 0.12 ENST00000257901.3
keratin 85
chr3_-_56950407 0.11 ENST00000496106.1
Rho guanine nucleotide exchange factor (GEF) 3
chr17_+_38375528 0.11 ENST00000583268.1
WAS/WASL interacting protein family, member 2
chr1_+_52521797 0.11 ENST00000313334.8
basic transcription factor 3-like 4
chr12_+_57810198 0.11 ENST00000598001.1
HCG1818482; Uncharacterized protein
chr11_-_798239 0.11 ENST00000531437.1
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr6_+_31554779 0.11 ENST00000376090.2
leukocyte specific transcript 1
chr12_-_323248 0.11 ENST00000535347.1
ENST00000536824.1
solute carrier family 6 (neurotransmitter transporter), member 12
chr11_-_506316 0.11 ENST00000532055.1
ENST00000531540.1
ribonuclease/angiogenin inhibitor 1
chr5_-_75008244 0.10 ENST00000510798.1
ENST00000446329.2
POC5 centriolar protein
chr6_+_24495185 0.10 ENST00000348925.2
aldehyde dehydrogenase 5 family, member A1
chr12_-_6716569 0.10 ENST00000544040.1
ENST00000545942.1
chromodomain helicase DNA binding protein 4
chr11_-_798305 0.10 ENST00000531514.1
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr19_-_9731872 0.10 ENST00000424629.1
ENST00000326044.5
ENST00000354661.4
ENST00000435550.1
ENST00000444611.1
ENST00000421525.1
zinc finger protein 561
chr6_+_31554962 0.10 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
leukocyte specific transcript 1
chr22_-_31063782 0.09 ENST00000404885.1
ENST00000403268.1
ENST00000407308.1
ENST00000342474.4
ENST00000334679.3
dual specificity phosphatase 18
chr1_-_110052302 0.09 ENST00000369864.4
ENST00000369862.1
adhesion molecule with Ig-like domain 1
chr4_-_147443043 0.09 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
solute carrier family 10, member 7
chr5_+_125935960 0.09 ENST00000297540.4
phosphorylated adaptor for RNA export
chr2_+_119981384 0.09 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP family member 3, metalloreductase
chr6_+_30978251 0.09 ENST00000561890.1
mucin 22
chr17_-_9725388 0.09 ENST00000399363.4
Putative germ cell-specific gene 1-like protein 2
chr6_-_24667180 0.09 ENST00000545995.1
tyrosyl-DNA phosphodiesterase 2
chr1_-_150693305 0.08 ENST00000368987.1
HORMA domain containing 1
chr1_-_46642154 0.08 ENST00000540385.1
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr6_+_76311568 0.08 ENST00000370014.3
SUMO1/sentrin specific peptidase 6
chr17_-_73267304 0.08 ENST00000579297.1
ENST00000580571.1
MIF4G domain containing
chr4_-_7436671 0.08 ENST00000319098.4
prosaposin-like 1 (gene/pseudogene)
chr6_-_24667232 0.08 ENST00000378198.4
tyrosyl-DNA phosphodiesterase 2
chr12_-_125473600 0.08 ENST00000308736.2
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr11_-_116663127 0.08 ENST00000433069.1
ENST00000542499.1
apolipoprotein A-V
chr17_+_58677539 0.08 ENST00000305921.3
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr4_-_171011323 0.08 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
aminoadipate aminotransferase
chr8_+_67624653 0.08 ENST00000521198.2
serum/glucocorticoid regulated kinase family, member 3
chr15_+_67430339 0.07 ENST00000439724.3
SMAD family member 3
chr5_+_140174429 0.07 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
protocadherin alpha 2
chr11_+_31531291 0.07 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr1_+_174968564 0.07 ENST00000426793.1
calcyclin binding protein
chr3_+_185304059 0.07 ENST00000427465.2
SUMO1/sentrin/SMT3 specific peptidase 2
chr11_-_116708302 0.07 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chrX_-_134429952 0.07 ENST00000370764.1
zinc finger protein 75D
chr1_-_86861660 0.06 ENST00000486215.1
outer dense fiber of sperm tails 2-like
chr14_-_24658053 0.06 ENST00000354464.6
importin 4
chr22_+_24819565 0.06 ENST00000424232.1
ENST00000486108.1
adenosine A2a receptor
chr16_+_56995854 0.06 ENST00000566128.1
cholesteryl ester transfer protein, plasma
chr4_+_2451700 0.06 ENST00000506607.1
Uncharacterized protein
chr17_+_26800756 0.06 ENST00000537681.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr4_-_147442982 0.06 ENST00000511374.1
ENST00000264986.3
solute carrier family 10, member 7
chr19_+_39881951 0.06 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
mediator complex subunit 29
chr9_-_3489406 0.06 ENST00000457373.1
regulatory factor X, 3 (influences HLA class II expression)
chr7_-_123198284 0.05 ENST00000355749.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr1_+_52521928 0.05 ENST00000489308.2
basic transcription factor 3-like 4
chr19_-_54761148 0.05 ENST00000316219.5
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
chr17_+_35767301 0.05 ENST00000225396.6
ENST00000417170.1
ENST00000590005.1
ENST00000590957.1
transcriptional adaptor 2A
chr2_-_21266816 0.05 ENST00000399256.4
apolipoprotein B
chr3_+_49297518 0.05 ENST00000440528.3
Uncharacterized protein
chr17_+_39994032 0.05 ENST00000293303.4
ENST00000438813.1
kelch-like family member 10
chr7_-_74489609 0.05 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
Williams-Beuren syndrome chromosome region 16
chr11_+_73360024 0.05 ENST00000540431.1
pleckstrin homology domain containing, family B (evectins) member 1
chr16_-_18923035 0.05 ENST00000563836.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr6_-_33771757 0.05 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
motilin
chr12_+_20522179 0.05 ENST00000359062.3
phosphodiesterase 3A, cGMP-inhibited
chr6_+_76311736 0.05 ENST00000447266.2
SUMO1/sentrin specific peptidase 6
chr2_+_7118755 0.04 ENST00000433456.1
ring finger protein 144A

Network of associatons between targets according to the STRING database.

First level regulatory network of RARB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.2 1.7 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0019860 uracil metabolic process(GO:0019860)
0.1 0.4 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0006043 glucosamine catabolic process(GO:0006043)
0.1 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.4 GO:0060032 notochord regression(GO:0060032)
0.1 0.5 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.4 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.8 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 0.2 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.1 0.4 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.6 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.3 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.6 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.3 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.3 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0019427 acetate metabolic process(GO:0006083) acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0010903 regulation of very-low-density lipoprotein particle remodeling(GO:0010901) negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.1 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 1.7 GO:0033503 HULC complex(GO:0033503)
0.1 0.2 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 0.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.5 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.0 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.2 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.2 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 2.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.9 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere