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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for REL

Z-value: 0.65

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Transcription factors associated with REL

Gene Symbol Gene ID Gene Info
REL
ENSG00000162924.9 REL proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELhg19_v2_chr2_+_61108771_611087910.253.0e-01Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_113594279 2.37 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr6_+_138188378 2.04 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_138188551 1.97 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr18_+_21529811 1.65 ENST00000588004.1
LAMA3
laminin, alpha 3
chr18_+_21452964 1.38 ENST00000587184.1
LAMA3
laminin, alpha 3
chr19_-_4338783 1.32 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr8_-_49834299 1.32 ENST00000396822.1
SNAI2
snail family zinc finger 2
chrX_+_115567767 1.31 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr18_+_21452804 1.30 ENST00000269217.6
LAMA3
laminin, alpha 3
chr19_-_4338838 1.30 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr18_+_33877654 1.27 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr11_-_58345569 1.27 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr5_-_149792295 1.24 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr4_+_74735102 1.23 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr9_-_117880477 1.22 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC
tenascin C
chr8_-_49833978 1.16 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr1_-_209824643 1.14 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr20_-_43977055 1.06 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chr9_+_130911723 1.05 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr19_-_51472031 1.05 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr12_-_95009837 1.05 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr6_+_138188351 0.98 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr9_+_130911770 0.97 ENST00000372998.1
LCN2
lipocalin 2
chr6_+_30850862 0.90 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_+_228678550 0.89 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr6_+_30850697 0.87 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr5_-_150467221 0.85 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr2_+_219745020 0.85 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr4_+_74702214 0.81 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr19_-_51471381 0.81 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr2_+_220094657 0.80 ENST00000436226.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr12_-_95010147 0.79 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr8_+_55466915 0.78 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr14_-_69262947 0.75 ENST00000557086.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr2_+_102314161 0.74 ENST00000425019.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr19_+_58193388 0.74 ENST00000596085.1
ENST00000594684.1
ZNF551
AC003006.7
zinc finger protein 551
Uncharacterized protein
chr19_-_4831701 0.74 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr19_-_39390212 0.72 ENST00000437828.1
SIRT2
sirtuin 2
chr20_-_36156264 0.71 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr1_-_27816556 0.70 ENST00000536657.1
WASF2
WAS protein family, member 2
chr20_-_36156125 0.69 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr3_-_112360116 0.68 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr2_+_220094479 0.66 ENST00000323348.5
ENST00000453432.1
ENST00000409849.1
ENST00000416565.1
ENST00000410034.3
ENST00000447157.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr3_+_101546827 0.64 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr19_+_41222998 0.62 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr1_+_16767195 0.62 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP2
NECAP endocytosis associated 2
chr7_+_18548878 0.62 ENST00000456174.2
HDAC9
histone deacetylase 9
chr10_-_105437909 0.61 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr5_+_82767284 0.61 ENST00000265077.3
VCAN
versican
chr16_+_67571351 0.60 ENST00000428437.2
ENST00000569253.1
FAM65A
family with sequence similarity 65, member A
chr14_-_69262916 0.60 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr21_-_34915084 0.59 ENST00000426819.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr6_+_15401075 0.58 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr8_-_23712312 0.58 ENST00000290271.2
STC1
stanniocalcin 1
chr6_+_292051 0.57 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr15_+_44719996 0.57 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_+_49963239 0.56 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr14_+_77648167 0.55 ENST00000554346.1
ENST00000298351.4
TMEM63C
transmembrane protein 63C
chr11_+_19798964 0.54 ENST00000527559.2
NAV2
neuron navigator 2
chr5_-_150460914 0.53 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr19_-_39390350 0.53 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr7_-_98741714 0.53 ENST00000361125.1
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr10_-_97050777 0.52 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr20_-_45530365 0.52 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr20_-_36156293 0.51 ENST00000373537.2
ENST00000414542.2
BLCAP
bladder cancer associated protein
chr5_+_150591678 0.51 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr7_+_18548924 0.51 ENST00000524023.1
HDAC9
histone deacetylase 9
chr5_+_154136702 0.50 ENST00000524248.1
LARP1
La ribonucleoprotein domain family, member 1
chr16_+_27325202 0.50 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R
interleukin 4 receptor
chr3_-_38071122 0.50 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr14_+_75988768 0.49 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr2_+_208394616 0.48 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr1_-_113249948 0.48 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chr19_-_39390440 0.47 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr16_-_75498450 0.46 ENST00000566594.1
RP11-77K12.1
Uncharacterized protein
chr17_-_6338472 0.46 ENST00000570466.1
ENST00000576776.1
ENST00000576307.1
ENST00000381129.3
ENST00000250087.5
AIPL1
aryl hydrocarbon receptor interacting protein-like 1
chr12_-_96793142 0.46 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr17_-_4642429 0.46 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr7_-_98741642 0.46 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr6_+_292253 0.45 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22
dual specificity phosphatase 22
chr19_-_9879293 0.45 ENST00000397902.2
ENST00000592859.1
ENST00000588267.1
ZNF846
zinc finger protein 846
chr10_+_13141585 0.44 ENST00000378764.2
OPTN
optineurin
chr4_-_146101304 0.43 ENST00000447906.2
OTUD4
OTU domain containing 4
chr1_-_29508321 0.42 ENST00000546138.1
SRSF4
serine/arginine-rich splicing factor 4
chr11_-_128392085 0.42 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr3_-_168864315 0.41 ENST00000475754.1
ENST00000484519.1
MECOM
MDS1 and EVI1 complex locus
chr12_-_76425368 0.41 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr1_-_9189144 0.41 ENST00000414642.2
GPR157
G protein-coupled receptor 157
chr13_-_48669204 0.41 ENST00000417167.1
MED4
mediator complex subunit 4
chr9_+_132934835 0.41 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr7_+_107384579 0.40 ENST00000222597.2
ENST00000415884.2
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr5_-_150466692 0.40 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr3_-_139108475 0.40 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr10_+_90750493 0.38 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr2_+_238600933 0.38 ENST00000420665.1
ENST00000392000.4
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr12_-_77272765 0.38 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2
cysteine and glycine-rich protein 2
chr12_-_57023995 0.38 ENST00000549884.1
ENST00000546695.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr21_-_34915123 0.37 ENST00000438059.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr15_+_44719790 0.37 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr11_+_10476851 0.37 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr2_-_74669009 0.36 ENST00000272430.5
RTKN
rhotekin
chr2_+_201987200 0.36 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr6_+_29910301 0.36 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr1_-_23694794 0.36 ENST00000374608.3
ZNF436
zinc finger protein 436
chr4_+_169418255 0.36 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr22_-_43036607 0.36 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr10_+_13142075 0.35 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr13_-_52027134 0.35 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr16_+_27324983 0.35 ENST00000566117.1
IL4R
interleukin 4 receptor
chr19_+_58193337 0.35 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
ZNF551
zinc finger protein 551
chr12_+_110718428 0.35 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr1_+_144339738 0.35 ENST00000538264.1
AL592284.1
Protein LOC642441
chr1_-_27816641 0.34 ENST00000430629.2
WASF2
WAS protein family, member 2
chr20_+_43803517 0.34 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr9_+_127054254 0.34 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr3_-_178789993 0.33 ENST00000432729.1
ZMAT3
zinc finger, matrin-type 3
chr9_+_72658490 0.33 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr17_-_4643161 0.33 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr5_-_115890554 0.33 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_57504069 0.33 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr3_+_42201653 0.32 ENST00000341421.3
ENST00000396175.1
TRAK1
trafficking protein, kinesin binding 1
chr5_+_43602750 0.32 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr19_-_51471362 0.32 ENST00000376853.4
ENST00000424910.2
KLK6
kallikrein-related peptidase 6
chr16_+_2820912 0.31 ENST00000570539.1
SRRM2
serine/arginine repetitive matrix 2
chr3_-_139108463 0.31 ENST00000512242.1
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr10_-_29923893 0.31 ENST00000355867.4
SVIL
supervillin
chr8_+_144816303 0.31 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr3_-_178789220 0.30 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr3_-_183967296 0.30 ENST00000455059.1
ENST00000445626.2
ALG3
ALG3, alpha-1,3- mannosyltransferase
chr22_+_46546494 0.29 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
PPARA
peroxisome proliferator-activated receptor alpha
chr14_+_75988851 0.29 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr5_+_133984462 0.29 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr7_+_69064300 0.29 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr10_+_13142225 0.29 ENST00000378747.3
OPTN
optineurin
chr1_+_45274154 0.29 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr5_-_141703713 0.29 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr4_-_103749205 0.28 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr6_+_142468383 0.28 ENST00000367621.1
ENST00000452973.2
VTA1
vesicle (multivesicular body) trafficking 1
chr14_-_69446034 0.27 ENST00000193403.6
ACTN1
actinin, alpha 1
chr11_+_19799327 0.27 ENST00000540292.1
NAV2
neuron navigator 2
chr8_+_123793633 0.25 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr7_+_156742399 0.25 ENST00000275820.3
NOM1
nucleolar protein with MIF4G domain 1
chr4_-_76957214 0.25 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr6_+_12008986 0.25 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr5_+_118604439 0.25 ENST00000388882.5
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr3_+_197518100 0.25 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr19_-_14064114 0.25 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr17_-_56492989 0.24 ENST00000583753.1
RNF43
ring finger protein 43
chr4_-_103749179 0.23 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_51632600 0.23 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
DAZAP2
DAZ associated protein 2
chr3_-_196230590 0.22 ENST00000318037.3
RNF168
ring finger protein 168, E3 ubiquitin protein ligase
chr15_+_93447675 0.22 ENST00000536619.1
CHD2
chromodomain helicase DNA binding protein 2
chr21_-_34915147 0.22 ENST00000381831.3
ENST00000381839.3
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr17_-_4643114 0.22 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr7_+_143771275 0.22 ENST00000408898.2
OR2A25
olfactory receptor, family 2, subfamily A, member 25
chr12_-_7281469 0.21 ENST00000542370.1
ENST00000266560.3
RBP5
retinol binding protein 5, cellular
chr1_-_35658736 0.21 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr14_-_36990061 0.21 ENST00000546983.1
NKX2-1
NK2 homeobox 1
chr1_-_27216729 0.21 ENST00000431781.2
ENST00000374135.4
GPN2
GPN-loop GTPase 2
chr4_+_26322185 0.21 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr13_-_52026730 0.21 ENST00000420668.2
INTS6
integrator complex subunit 6
chr14_+_68086515 0.21 ENST00000261783.3
ARG2
arginase 2
chr16_-_75498553 0.20 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A
RP11-77K12.1
transmembrane protein 170A
Uncharacterized protein
chr19_+_57752200 0.20 ENST00000414468.2
ZNF805
zinc finger protein 805
chr3_+_179322481 0.20 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr11_-_104893863 0.20 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5
caspase 5, apoptosis-related cysteine peptidase
chr16_+_3096638 0.19 ENST00000336577.4
MMP25
matrix metallopeptidase 25
chr2_+_208394794 0.19 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1
cAMP responsive element binding protein 1
chr11_-_7961141 0.19 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr16_+_50730910 0.19 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr17_-_8286484 0.19 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr19_-_6279932 0.18 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr2_+_162016827 0.18 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr9_-_132805430 0.18 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr3_+_57261743 0.18 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr8_+_55467072 0.18 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr22_-_41252962 0.17 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr22_-_39268192 0.17 ENST00000216083.6
CBX6
chromobox homolog 6
chr4_-_185395672 0.17 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr20_+_44486246 0.17 ENST00000255152.2
ENST00000454862.2
ZSWIM3
zinc finger, SWIM-type containing 3
chr10_+_90750378 0.17 ENST00000355740.2
ENST00000352159.4
FAS
Fas cell surface death receptor
chr17_-_73178599 0.17 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr3_+_141596371 0.17 ENST00000495216.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr19_-_57967854 0.17 ENST00000321039.3
VN1R1
vomeronasal 1 receptor 1
chr2_+_63277927 0.17 ENST00000282549.2
OTX1
orthodenticle homeobox 1
chr11_+_119038897 0.17 ENST00000454811.1
ENST00000449394.1
NLRX1
NLR family member X1
chr12_-_118490403 0.16 ENST00000535496.1
WSB2
WD repeat and SOCS box containing 2
chr11_+_66406149 0.16 ENST00000578778.1
ENST00000483858.1
ENST00000398692.4
ENST00000510173.2
ENST00000506523.2
ENST00000530235.1
ENST00000532968.1
RBM4
RNA binding motif protein 4
chr16_+_15737124 0.16 ENST00000396355.1
ENST00000396353.2
NDE1
nudE neurodevelopment protein 1
chr2_-_43453734 0.16 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr6_-_88299678 0.16 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr12_+_56211703 0.16 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
ORMDL2
ORM1-like 2 (S. cerevisiae)
chr20_+_44746939 0.16 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr15_+_52311398 0.16 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr2_+_131975882 0.16 ENST00000356920.5
ENST00000358087.5
POTEE
POTE ankyrin domain family, member E
chr17_+_26662730 0.15 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr14_-_35873856 0.15 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr21_+_34775772 0.15 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr1_+_156117149 0.15 ENST00000435124.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr9_+_127054217 0.15 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.8 2.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6 1.7 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.4 0.4 GO:0045210 FasL biosynthetic process(GO:0045210)
0.4 2.0 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4 1.8 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 1.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.3 0.9 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 2.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.3 1.3 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2 1.2 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 1.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 1.0 GO:1902534 single-organism membrane invagination(GO:1902534)
0.2 1.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 5.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.7 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 2.0 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 1.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 1.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.7 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.1 0.8 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 0.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.5 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.5 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.5 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.1 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 1.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.2 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.4 GO:0030578 PML body organization(GO:0030578)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0060584 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 1.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 1.1 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 1.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 1.9 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.6 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.4 GO:1903943 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:1902231 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 2.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.3 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.3 GO:0007620 copulation(GO:0007620)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.5 GO:0036293 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.0 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.5 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.7 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 2.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 2.6 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 2.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.6 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.7 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.3 1.2 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.3 0.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 4.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.9 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.2 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.2 GO:0045545 syndecan binding(GO:0045545)
0.1 1.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 2.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.7 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.0 GO:0048185 activin binding(GO:0048185)
0.0 1.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 3.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 3.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 2.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 2.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 5.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)