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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RELA

Z-value: 1.11

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Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
RELA
ENSG00000173039.14 RELA proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELAhg19_v2_chr11_-_65430554_654305790.512.2e-02Click!

Activity profile of RELA motif

Sorted Z-values of RELA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_74964904 4.10 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr4_+_74735102 3.63 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr6_+_138188551 3.60 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_+_228678550 3.28 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr6_+_138188378 3.22 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_-_74904398 3.06 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr19_+_10381769 2.62 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr6_+_138188351 2.51 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_-_209825674 2.46 ENST00000367030.3
ENST00000356082.4
LAMB3
laminin, beta 3
chr5_-_149792295 2.44 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr11_+_18287801 2.34 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr11_+_34642656 2.33 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr14_-_35873856 2.28 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr11_+_18287721 2.27 ENST00000356524.4
SAA1
serum amyloid A1
chr1_+_46640750 2.27 ENST00000372003.1
TSPAN1
tetraspanin 1
chr7_+_22766766 2.11 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr3_+_101546827 2.06 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chrX_-_73072534 1.97 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr22_-_37640277 1.83 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_-_28124903 1.83 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr5_-_141257954 1.76 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr1_-_209979375 1.76 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr22_-_37640456 1.72 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_-_4338838 1.62 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr19_-_4338783 1.57 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr5_-_150460914 1.46 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr11_-_58345569 1.39 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr19_-_4831701 1.39 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr2_+_219745020 1.28 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr4_+_74702214 1.27 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr5_+_159895275 1.26 ENST00000517927.1
MIR146A
microRNA 146a
chr1_-_39395165 1.26 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr6_-_31550192 1.21 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr6_+_30850697 1.15 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr6_+_29691198 1.14 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr1_+_6845384 1.12 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr5_-_150460539 1.09 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr1_-_209824643 1.07 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr2_+_233925064 1.02 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr20_+_1115821 1.00 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr4_-_76944621 1.00 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_-_32636145 0.98 ENST00000399084.1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr19_-_39390212 0.97 ENST00000437828.1
SIRT2
sirtuin 2
chr19_-_51472031 0.96 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr20_-_43977055 0.95 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chr19_-_54984354 0.87 ENST00000301200.2
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr5_-_150467221 0.86 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr2_+_17721920 0.85 ENST00000295156.4
VSNL1
visinin-like 1
chr10_-_105437909 0.83 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr2_+_234602305 0.83 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr6_-_30712313 0.80 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr14_-_103589246 0.78 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr7_+_143078652 0.78 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr2_-_163175133 0.76 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr20_+_44746885 0.73 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr6_+_30850862 0.72 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr19_-_51471381 0.71 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr11_+_94501497 0.70 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
AMOTL1
angiomotin like 1
chr10_+_75668916 0.70 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr14_+_75988768 0.69 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr19_-_11688500 0.69 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr10_+_13141585 0.69 ENST00000378764.2
OPTN
optineurin
chr16_+_67571351 0.69 ENST00000428437.2
ENST00000569253.1
FAM65A
family with sequence similarity 65, member A
chr7_+_18548878 0.68 ENST00000456174.2
HDAC9
histone deacetylase 9
chr20_-_45530365 0.67 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr6_+_29910301 0.67 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr5_+_110407390 0.67 ENST00000344895.3
TSLP
thymic stromal lymphopoietin
chr6_-_29527702 0.65 ENST00000377050.4
UBD
ubiquitin D
chr1_+_24645807 0.64 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr3_-_111852061 0.62 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr3_-_168864315 0.61 ENST00000475754.1
ENST00000484519.1
MECOM
MDS1 and EVI1 complex locus
chr4_-_76957214 0.60 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr17_-_56492989 0.59 ENST00000583753.1
RNF43
ring finger protein 43
chr1_+_24646002 0.58 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr16_+_50775971 0.58 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr12_+_48499883 0.58 ENST00000546755.1
ENST00000549366.1
ENST00000552792.1
PFKM
phosphofructokinase, muscle
chr5_-_150466692 0.58 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr6_+_29691056 0.58 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr20_-_62203808 0.58 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr20_-_36156125 0.58 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr16_+_50775948 0.57 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr6_-_150039170 0.57 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr7_+_18548924 0.56 ENST00000524023.1
HDAC9
histone deacetylase 9
chr1_+_24645865 0.56 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_36615065 0.56 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr11_-_96076334 0.56 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr2_+_17721937 0.56 ENST00000451533.1
VSNL1
visinin-like 1
chr19_-_11688447 0.55 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr19_-_39390350 0.54 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr2_-_74669009 0.54 ENST00000272430.5
RTKN
rhotekin
chr19_-_11688260 0.54 ENST00000590832.1
ACP5
acid phosphatase 5, tartrate resistant
chr10_+_13142075 0.54 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr19_+_41222998 0.53 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr16_+_50776021 0.53 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr10_+_13142225 0.52 ENST00000378747.3
OPTN
optineurin
chr10_+_104154229 0.52 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr11_-_57194111 0.51 ENST00000529112.1
ENST00000529896.1
SLC43A3
solute carrier family 43, member 3
chr3_+_111578131 0.51 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr3_+_184032919 0.51 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_+_118754475 0.50 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr19_-_39390440 0.49 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr14_+_75988851 0.49 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr15_+_44719996 0.48 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_-_186649543 0.48 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_151171012 0.48 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr1_+_24645915 0.48 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr3_-_49131473 0.47 ENST00000430979.1
ENST00000357496.2
ENST00000437939.1
QRICH1
glutamine-rich 1
chr1_+_156123359 0.47 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_+_38758845 0.47 ENST00000519640.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr1_-_153935983 0.47 ENST00000537590.1
ENST00000356205.4
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr15_+_42066888 0.46 ENST00000510535.1
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr1_-_1822495 0.46 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr19_-_9879293 0.46 ENST00000397902.2
ENST00000592859.1
ENST00000588267.1
ZNF846
zinc finger protein 846
chr7_+_143078379 0.45 ENST00000449630.1
ENST00000457235.1
ZYX
zyxin
chr3_+_53195136 0.45 ENST00000394729.2
ENST00000330452.3
PRKCD
protein kinase C, delta
chr14_-_69262947 0.44 ENST00000557086.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr1_-_110613276 0.44 ENST00000369792.4
ALX3
ALX homeobox 3
chr14_-_69262789 0.44 ENST00000557022.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr1_-_36615051 0.43 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr7_-_98741714 0.43 ENST00000361125.1
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr1_-_153935938 0.43 ENST00000368621.1
ENST00000368623.3
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr4_+_146560245 0.43 ENST00000541599.1
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr7_-_98741642 0.43 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr20_-_36156264 0.43 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr14_+_73704201 0.42 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr1_-_113249734 0.42 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr12_+_11802753 0.42 ENST00000396373.4
ETV6
ets variant 6
chr3_+_111578027 0.41 ENST00000431670.2
ENST00000412622.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr12_-_76425368 0.41 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr21_+_34775698 0.41 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr10_-_7708918 0.41 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr20_-_36156293 0.41 ENST00000373537.2
ENST00000414542.2
BLCAP
bladder cancer associated protein
chr4_-_103749205 0.40 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr21_+_34775772 0.40 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr17_+_40440481 0.39 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr16_-_66959429 0.39 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr7_+_69064300 0.39 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr5_-_178054014 0.39 ENST00000520957.1
CLK4
CDC-like kinase 4
chr1_-_113249678 0.39 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr11_-_8832182 0.39 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5
suppression of tumorigenicity 5
chr6_+_292051 0.38 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr18_+_32290218 0.38 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr11_+_118478313 0.38 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr2_+_201987200 0.37 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_-_205744574 0.37 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr10_+_99609996 0.37 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr16_+_67465016 0.36 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr6_+_135502466 0.36 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr6_+_87865262 0.36 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr8_-_11058847 0.35 ENST00000297303.4
ENST00000416569.2
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr3_-_49131013 0.34 ENST00000424300.1
QRICH1
glutamine-rich 1
chr5_-_132112907 0.34 ENST00000458488.2
SEPT8
septin 8
chr7_+_143771275 0.34 ENST00000408898.2
OR2A25
olfactory receptor, family 2, subfamily A, member 25
chr9_+_127054254 0.34 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr3_+_184033135 0.34 ENST00000424196.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr3_+_9439579 0.34 ENST00000406341.1
SETD5
SET domain containing 5
chr1_-_38100539 0.33 ENST00000401069.1
RSPO1
R-spondin 1
chr5_+_150591678 0.33 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr3_+_9439400 0.33 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
SETD5
SET domain containing 5
chr11_-_128392085 0.33 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr2_+_97202480 0.33 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr5_+_82767284 0.33 ENST00000265077.3
VCAN
versican
chr19_+_6740888 0.32 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr5_-_142077569 0.32 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr16_+_50730910 0.32 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr7_+_134464376 0.32 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr9_+_132934835 0.31 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr15_+_44719790 0.31 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr16_+_67282853 0.31 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr14_-_69446034 0.31 ENST00000193403.6
ACTN1
actinin, alpha 1
chr9_-_130693048 0.30 ENST00000388747.4
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr4_-_103749179 0.30 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr7_-_27169801 0.30 ENST00000511914.1
HOXA4
homeobox A4
chr13_-_52027134 0.30 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr5_+_140787600 0.30 ENST00000520790.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr6_+_106534192 0.29 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr11_+_65190245 0.29 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr19_+_45251804 0.29 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr3_-_111852128 0.29 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr5_-_132113063 0.29 ENST00000378719.2
SEPT8
septin 8
chr16_+_3096638 0.29 ENST00000336577.4
MMP25
matrix metallopeptidase 25
chr1_-_89738528 0.28 ENST00000343435.5
GBP5
guanylate binding protein 5
chr6_+_33378517 0.28 ENST00000428274.1
PHF1
PHD finger protein 1
chr14_-_69262916 0.28 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr8_+_55466915 0.28 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr1_+_156123318 0.27 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_23694794 0.27 ENST00000374608.3
ZNF436
zinc finger protein 436
chrX_+_152907913 0.27 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr7_-_137531606 0.27 ENST00000288490.5
DGKI
diacylglycerol kinase, iota
chr11_+_10476851 0.27 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr2_+_97203082 0.27 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr15_+_57884117 0.26 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr6_+_32605134 0.26 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr14_+_61789382 0.26 ENST00000555082.1
PRKCH
protein kinase C, eta
chr19_-_51471362 0.26 ENST00000376853.4
ENST00000424910.2
KLK6
kallikrein-related peptidase 6
chr2_+_208394616 0.26 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr1_-_236030216 0.25 ENST00000389794.3
ENST00000389793.2
LYST
lysosomal trafficking regulator
chr14_+_32798462 0.25 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr19_-_11688951 0.25 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant
chr11_-_62446527 0.24 ENST00000294119.2
ENST00000529640.1
ENST00000534176.1
ENST00000301935.5
UBXN1
UBX domain protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
1.1 3.3 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.8 4.0 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.7 2.0 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.6 16.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.6 1.7 GO:1990108 protein linear deubiquitination(GO:1990108)
0.5 2.1 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.5 2.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.4 2.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 0.7 GO:0035065 regulation of histone acetylation(GO:0035065) regulation of peptidyl-lysine acetylation(GO:2000756)
0.3 1.2 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.3 2.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 2.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.7 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 1.2 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2 0.9 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.2 1.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 1.4 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 1.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 1.0 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.9 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 0.5 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 0.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.9 GO:1902534 single-organism membrane invagination(GO:1902534)
0.2 1.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.7 GO:0033590 response to cobalamin(GO:0033590)
0.1 0.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.8 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 1.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.4 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.8 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 2.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 4.4 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 1.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 1.9 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.3 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 3.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0072616 interleukin-18 secretion(GO:0072616)
0.1 0.2 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 1.3 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.5 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.2 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.3 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.1 1.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 1.8 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 1.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.3 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.2 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 2.1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.3 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0046959 habituation(GO:0046959)
0.0 0.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858)
0.0 1.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.6 GO:0016485 protein processing(GO:0016485)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 1.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.6 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 GO:0005610 laminin-5 complex(GO:0005610)
0.3 2.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 2.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.9 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 2.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 2.0 GO:0072687 meiotic spindle(GO:0072687)
0.1 4.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.7 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.8 GO:0097342 ripoptosome(GO:0097342)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 1.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.0 2.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 3.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 3.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 2.4 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 1.0 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.7 GO:0097542 ciliary tip(GO:0097542)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.9 13.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.7 2.0 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.6 11.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 2.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 1.7 GO:0046979 TAP2 binding(GO:0046979)
0.2 1.0 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 1.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.5 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 2.0 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.5 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 1.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 6.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.6 GO:0070628 proteasome binding(GO:0070628)
0.1 0.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 3.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.2 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 2.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.9 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849) virion binding(GO:0046790)
0.0 0.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0005095 diacylglycerol kinase activity(GO:0004143) GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 6.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 6.5 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 3.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 2.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 3.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 5.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 2.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 8.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 12.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 6.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 3.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 2.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis