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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RFX3_RFX2

Z-value: 2.93

Motif logo

Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
ENSG00000080298.11 regulatory factor X3
ENSG00000087903.8 regulatory factor X2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg19_v2_chr19_-_6110474_61105510.697.0e-04Click!
RFX3hg19_v2_chr9_-_3525968_3526016-0.464.0e-02Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_48693955 19.24 ENST00000218230.5
proprotein convertase subtilisin/kexin type 1 inhibitor
chr12_+_48577366 12.74 ENST00000316554.3
chromosome 12 open reading frame 68
chr5_-_179780312 11.29 ENST00000253778.8
glutamine-fructose-6-phosphate transaminase 2
chr5_+_176873789 7.80 ENST00000323249.3
ENST00000502922.1
proline rich 7 (synaptic)
chr2_+_74648848 7.77 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WD repeat domain 54
chr19_-_55791058 7.73 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr5_+_92919043 7.71 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr16_-_67427389 7.43 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr19_-_59084647 7.28 ENST00000594234.1
ENST00000596039.1
myeloid zinc finger 1
chr12_-_58329888 7.13 ENST00000546580.1
RP11-620J15.3
chr17_+_43318434 7.10 ENST00000587489.1
formin-like 1
chr11_+_133938820 7.06 ENST00000299106.4
ENST00000529443.2
junctional adhesion molecule 3
chr9_-_131418944 6.97 ENST00000419989.1
ENST00000451652.1
ENST00000372715.2
WD repeat domain 34
chr19_-_59084922 6.95 ENST00000215057.2
ENST00000599369.1
myeloid zinc finger 1
chr9_-_35103105 6.91 ENST00000452248.2
ENST00000356493.5
stomatin (EPB72)-like 2
chr19_+_17413663 6.68 ENST00000594999.1
mitochondrial ribosomal protein L34
chr11_-_6426635 6.57 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr2_-_74648702 6.56 ENST00000518863.1
chromosome 2 open reading frame 81
chr16_-_30773372 6.25 ENST00000545825.1
ENST00000541260.1
chromosome 16 open reading frame 93
chr14_-_57960456 5.93 ENST00000534126.1
ENST00000422976.2
chromosome 14 open reading frame 105
chr1_-_21978312 5.89 ENST00000359708.4
ENST00000290101.4
RAP1 GTPase activating protein
chr7_-_35077653 5.77 ENST00000310974.4
dpy-19-like 1 (C. elegans)
chr14_+_105992906 5.76 ENST00000392519.2
transmembrane protein 121
chr11_-_115375107 5.72 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chr6_-_24646249 5.68 ENST00000430948.2
ENST00000537886.1
ENST00000535378.1
ENST00000378214.3
KIAA0319
chr14_-_57960545 5.68 ENST00000526336.1
ENST00000216445.3
chromosome 14 open reading frame 105
chr16_-_57836321 5.62 ENST00000569112.1
ENST00000562311.1
ENST00000445690.2
ENST00000379655.4
kinesin family member C3
chr10_+_104178946 5.61 ENST00000432590.1
F-box and leucine-rich repeat protein 15
chr16_-_30022735 5.52 ENST00000564944.1
double C2-like domains, alpha
chr19_+_54385439 5.44 ENST00000536044.1
ENST00000540413.1
ENST00000263431.3
ENST00000419486.1
protein kinase C, gamma
chr1_-_167905225 5.34 ENST00000367846.4
mitochondrial pyruvate carrier 2
chr12_-_58329819 5.30 ENST00000551421.1
RP11-620J15.3
chr11_-_64885111 5.08 ENST00000528598.1
ENST00000310597.4
zinc finger, HIT-type containing 2
chr3_+_48507210 5.07 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
three prime repair exonuclease 1
chr2_+_121103706 5.07 ENST00000295228.3
inhibin, beta B
chr7_+_150065278 4.99 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr3_+_149192475 4.91 ENST00000465758.1
transmembrane 4 L six family member 4
chr11_+_844406 4.87 ENST00000397404.1
tetraspanin 4
chr8_+_144451039 4.86 ENST00000289013.6
rhophilin, Rho GTPase binding protein 1
chr14_+_76044934 4.83 ENST00000238667.4
feline leukemia virus subgroup C cellular receptor family, member 2
chr16_-_30022293 4.82 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
double C2-like domains, alpha
chr19_-_58892389 4.76 ENST00000427624.2
ENST00000597582.1
zinc finger protein 837
chr11_+_133938955 4.74 ENST00000534549.1
ENST00000441717.3
junctional adhesion molecule 3
chr12_+_53693466 4.73 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr7_+_129142320 4.71 ENST00000462322.2
small lysine-rich protein 1
chr15_-_71184724 4.66 ENST00000560604.1
THAP domain containing 10
chr19_-_58874112 4.55 ENST00000311044.3
ENST00000595763.1
ENST00000425453.3
zinc finger protein 497
chr19_-_55791431 4.44 ENST00000593263.1
ENST00000376343.3
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chrX_-_106449656 4.38 ENST00000372466.4
ENST00000421752.1
ENST00000372461.3
nucleoporin 62kDa C-terminal like
chr11_-_559377 4.38 ENST00000486629.1
chromosome 11 open reading frame 35
chr11_+_101918153 4.37 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
chromosome 11 open reading frame 70
chr19_-_41870026 4.31 ENST00000243578.3
B9 protein domain 2
chr7_+_150065879 4.28 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
replication initiator 1
zinc finger protein 775
chr15_-_65282274 4.15 ENST00000204566.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr4_-_155511887 4.07 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr2_-_233792837 4.07 ENST00000373552.4
ENST00000409079.1
neuronal guanine nucleotide exchange factor
chr15_+_71184931 4.06 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr3_+_48507621 4.00 ENST00000456089.1
three prime repair exonuclease 1
chr15_-_65282232 3.98 ENST00000416889.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr2_+_27070964 3.98 ENST00000288699.6
dihydropyrimidinase-like 5
chr17_-_26662464 3.96 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
intraflagellar transport 20 homolog (Chlamydomonas)
chr11_-_28129656 3.95 ENST00000263181.6
kinesin family member 18A
chr7_-_37026108 3.93 ENST00000396045.3
engulfment and cell motility 1
chr12_+_53693812 3.90 ENST00000549488.1
chromosome 12 open reading frame 10
chr9_-_4666421 3.90 ENST00000381895.5
spermatogenesis associated 6-like
chrX_-_71351678 3.84 ENST00000609883.1
ENST00000545866.1
retrotransposon gag domain containing 4
chr15_+_69706585 3.81 ENST00000559279.1
ENST00000395392.2
kinesin family member 23
chr19_-_55791540 3.76 ENST00000433386.2
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr12_-_58146048 3.70 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr18_+_44526786 3.66 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chr1_+_155178481 3.64 ENST00000368376.3
metaxin 1
chr3_-_49055991 3.62 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALR anticodon binding domain containing 3
chr12_-_63328817 3.62 ENST00000228705.6
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr20_+_42984330 3.59 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
hepatocyte nuclear factor 4, alpha
chr11_+_47600562 3.58 ENST00000263774.4
ENST00000529276.1
ENST00000528192.1
ENST00000530295.1
ENST00000534208.1
ENST00000534716.2
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
chr2_-_130902567 3.56 ENST00000457413.1
ENST00000392984.3
ENST00000409128.1
ENST00000441670.1
ENST00000409943.3
ENST00000409234.3
ENST00000310463.6
coiled-coil domain containing 74B
chr12_-_58146128 3.56 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr17_+_78389247 3.55 ENST00000520136.2
ENST00000520284.1
ENST00000517795.1
ENST00000523228.1
ENST00000523828.1
ENST00000522200.1
ENST00000521565.1
ENST00000518907.1
ENST00000518644.1
ENST00000518901.1
endonuclease V
chr4_+_2043689 3.55 ENST00000382878.3
ENST00000409248.4
chromosome 4 open reading frame 48
chr6_-_24645956 3.52 ENST00000543707.1
KIAA0319
chr15_+_71185148 3.50 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr15_+_69706643 3.47 ENST00000352331.4
ENST00000260363.4
kinesin family member 23
chr1_+_155178518 3.47 ENST00000316721.4
metaxin 1
chr15_-_65281775 3.47 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr12_-_64062241 3.46 ENST00000538147.1
ENST00000324472.4
dpy-19-like 2 (C. elegans)
chr17_-_7760779 3.46 ENST00000335155.5
ENST00000575071.1
LSM domain containing 1
chr17_-_73840415 3.45 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
unc-13 homolog D (C. elegans)
chr14_+_100259666 3.45 ENST00000262233.6
ENST00000334192.4
echinoderm microtubule associated protein like 1
chr7_-_156433195 3.41 ENST00000333319.6
chromosome 7 open reading frame 13
chr21_-_44846999 3.41 ENST00000270162.6
salt-inducible kinase 1
chr19_+_19639704 3.39 ENST00000514277.4
YjeF N-terminal domain containing 3
chr11_-_27384737 3.37 ENST00000317945.6
coiled-coil domain containing 34
chr2_+_132285406 3.37 ENST00000295171.6
ENST00000409856.3
coiled-coil domain containing 74A
chr16_-_67450325 3.35 ENST00000348579.2
zinc finger, DHHC-type containing 1
chr17_-_7108436 3.35 ENST00000493294.1
discs, large homolog 4 (Drosophila)
chr5_-_54529415 3.35 ENST00000282572.4
cyclin O
chr17_-_53046058 3.34 ENST00000571584.1
ENST00000299335.3
cytochrome c oxidase assembly homolog 11 (yeast)
chr8_+_21912328 3.32 ENST00000432128.1
ENST00000443491.2
ENST00000517600.1
ENST00000523782.2
dematin actin binding protein
chr19_+_19639670 3.28 ENST00000436027.5
YjeF N-terminal domain containing 3
chr19_-_17356697 3.27 ENST00000291442.3
nuclear receptor subfamily 2, group F, member 6
chr10_+_124030819 3.27 ENST00000260723.4
ENST00000368994.2
BTB (POZ) domain containing 16
chr11_-_62473706 3.26 ENST00000403550.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_-_134145321 3.25 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
serine/threonine kinase 32C
chr16_+_2076869 3.23 ENST00000424542.2
ENST00000432365.2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr14_+_105941118 3.23 ENST00000550577.1
ENST00000538259.2
cysteine-rich protein 2
chr11_-_62473776 3.18 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_+_61447845 3.16 ENST00000257215.5
diacylglycerol lipase, alpha
chr10_-_135150367 3.15 ENST00000368555.3
ENST00000252939.4
ENST00000368558.1
ENST00000368556.2
calcyon neuron-specific vesicular protein
chr12_+_7014064 3.13 ENST00000443597.2
leucine rich repeat containing 23
chr6_-_135818844 3.13 ENST00000524469.1
ENST00000367800.4
ENST00000327035.6
ENST00000457866.2
ENST00000265602.6
Abelson helper integration site 1
chr2_+_74682150 3.10 ENST00000233331.7
ENST00000431187.1
ENST00000409917.1
ENST00000409493.2
INO80 complex subunit B
chr9_+_131084846 3.06 ENST00000608951.1
coenzyme Q4
chr11_-_124981475 3.05 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr2_-_175869936 3.01 ENST00000409900.3
chimerin 1
chr19_-_1490398 2.99 ENST00000588671.1
ENST00000300954.5
proprotein convertase subtilisin/kexin type 4
chr12_+_6930964 2.88 ENST00000382315.3
G protein-coupled receptor 162
chr17_+_2240775 2.87 ENST00000268989.3
ENST00000426855.2
small G protein signaling modulator 2
chr1_-_63988846 2.86 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
integrin beta 3 binding protein (beta3-endonexin)
chr12_-_64062583 2.84 ENST00000542209.1
dpy-19-like 2 (C. elegans)
chr4_+_2043777 2.81 ENST00000409860.1
chromosome 4 open reading frame 48
chr20_+_43160409 2.80 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chrX_+_48455866 2.79 ENST00000376729.5
ENST00000218056.5
WD repeat domain 13
chr3_+_149689066 2.79 ENST00000593416.1
LOC646903 protein; Uncharacterized protein
chr20_-_3762087 2.77 ENST00000379756.3
sperm flagellar 1
chr17_-_26662440 2.75 ENST00000578122.1
intraflagellar transport 20 homolog (Chlamydomonas)
chr22_-_38240316 2.73 ENST00000411961.2
ENST00000434930.1
ankyrin repeat domain 54
chr2_-_74699770 2.72 ENST00000409710.1
mitochondrial ribosomal protein L53
chrX_+_129473916 2.71 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr17_-_16472483 2.70 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
zinc finger protein 287
chr17_-_7761172 2.70 ENST00000333775.5
ENST00000575771.1
LSM domain containing 1
chr9_-_4666337 2.69 ENST00000381890.5
spermatogenesis associated 6-like
chr19_+_50879705 2.68 ENST00000598168.1
ENST00000411902.2
ENST00000253727.5
ENST00000597790.1
ENST00000597130.1
ENST00000599105.1
nuclear receptor subfamily 1, group H, member 2
chr2_+_170335924 2.66 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
Bardet-Biedl syndrome 5
Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr7_+_102073966 2.63 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI calcium release-activated calcium modulator 2
chr1_+_155179012 2.62 ENST00000609421.1
metaxin 1
chr19_+_18530146 2.61 ENST00000348495.6
ENST00000270061.7
single stranded DNA binding protein 4
chr10_+_73156664 2.59 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
cadherin-related 23
chr9_+_131084815 2.56 ENST00000300452.3
ENST00000609948.1
coenzyme Q4
chr17_+_62075703 2.55 ENST00000577953.1
ENST00000582540.1
ENST00000579184.1
ENST00000425164.3
ENST00000412177.1
ENST00000539996.1
ENST00000583891.1
ENST00000580752.1
chromosome 17 open reading frame 72
chr17_-_19265982 2.54 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9 protein domain 1
chr12_+_7013897 2.51 ENST00000007969.8
ENST00000323702.5
leucine rich repeat containing 23
chr12_+_9067327 2.49 ENST00000433083.2
ENST00000544916.1
ENST00000544539.1
ENST00000539063.1
polyhomeotic homolog 1 (Drosophila)
chr6_+_112408768 2.47 ENST00000368656.2
ENST00000604268.1
family with sequence similarity 229, member B
chr19_+_13842559 2.47 ENST00000586600.1
coiled-coil domain containing 130
chr2_-_175870085 2.46 ENST00000409156.3
chimerin 1
chr8_+_22462532 2.46 ENST00000389279.3
cell cycle and apoptosis regulator 2
chr11_+_66360665 2.42 ENST00000310190.4
copper chaperone for superoxide dismutase
chr16_+_29823427 2.42 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
proline-rich transmembrane protein 2
chr8_+_120428546 2.40 ENST00000259526.3
nephroblastoma overexpressed
chr6_+_135818979 2.39 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
long intergenic non-protein coding RNA 271
chr6_+_31783291 2.39 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr3_+_49027308 2.38 ENST00000383729.4
ENST00000343546.4
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr17_-_19266045 2.38 ENST00000395616.3
B9 protein domain 1
chr19_-_55791563 2.37 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr17_-_19265855 2.36 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9 protein domain 1
chr19_+_1450112 2.33 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
adenomatosis polyposis coli 2
chr11_+_8040739 2.31 ENST00000534099.1
tubby bipartite transcription factor
chr19_-_55677999 2.30 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
dynein, axonemal, assembly factor 3
chr2_+_27071045 2.30 ENST00000401478.1
dihydropyrimidinase-like 5
chr19_-_633576 2.30 ENST00000588649.2
polymerase (RNA) mitochondrial (DNA directed)
chr12_+_9067123 2.29 ENST00000543824.1
polyhomeotic homolog 1 (Drosophila)
chr2_-_241497374 2.29 ENST00000373318.2
ENST00000406958.1
ENST00000391987.1
ENST00000373320.4
ankyrin repeat and MYND domain containing 1
chr19_+_56652556 2.28 ENST00000337080.3
zinc finger protein 444
chr6_+_30525051 2.28 ENST00000376557.3
proline rich 3
chr16_-_29910365 2.28 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
seizure related 6 homolog (mouse)-like 2
chr1_-_156217829 2.27 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
progestin and adipoQ receptor family member VI
chr2_+_219221573 2.24 ENST00000289388.3
chromosome 2 open reading frame 62
chr19_-_7553889 2.24 ENST00000221480.1
peroxisomal biogenesis factor 11 gamma
chr2_-_38978492 2.24 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
serine/arginine-rich splicing factor 7
chr17_+_78010428 2.21 ENST00000397545.4
ENST00000374877.3
ENST00000269318.5
ENST00000374876.4
ENST00000576033.1
ENST00000574099.1
coiled-coil domain containing 40
chr14_+_77787227 2.21 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
glutathione S-transferase zeta 1
chr20_+_43160458 2.20 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr6_-_32119877 2.19 ENST00000375152.2
proline-rich transmembrane protein 1
chr12_-_131323754 2.19 ENST00000261653.6
syntaxin 2
chr11_-_62473684 2.19 ENST00000448568.2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr17_+_2240916 2.18 ENST00000574563.1
small G protein signaling modulator 2
chr19_-_40324767 2.18 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr2_+_220462560 2.16 ENST00000456909.1
ENST00000295641.10
serine/threonine kinase 11 interacting protein
chr6_+_30524663 2.15 ENST00000376560.3
proline rich 3
chr3_-_118753716 2.14 ENST00000393775.2
immunoglobulin superfamily, member 11
chr14_+_24025194 2.14 ENST00000404535.3
ENST00000288014.6
thiamine triphosphatase
chr3_-_118753626 2.14 ENST00000489689.1
immunoglobulin superfamily, member 11
chr17_-_41277467 2.12 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
breast cancer 1, early onset
chr22_+_30752606 2.12 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
coiled-coil domain containing 157
chr17_-_7761256 2.10 ENST00000575208.1
LSM domain containing 1
chr19_-_55677920 2.09 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
dynein, axonemal, assembly factor 3
chr11_+_17298255 2.09 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
nucleobindin 2
chr16_+_67840986 2.08 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
translin-associated factor X interacting protein 1
chr17_-_7760457 2.07 ENST00000576384.1
LSM domain containing 1
chr17_+_78388959 2.07 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
endonuclease V
chr7_-_99699538 2.04 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr19_+_48949030 2.04 ENST00000253237.5
glutamate-rich WD repeat containing 1
chr15_+_90777424 2.03 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDP-D-glucose phosphorylase 1
chr16_+_89724434 2.01 ENST00000568929.1
spermatogenesis associated 33
chr6_-_32119676 2.00 ENST00000211413.5
proline-rich transmembrane protein 1
chr19_+_39616410 2.00 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
p21 protein (Cdc42/Rac)-activated kinase 4
chr9_+_136325089 2.00 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
calcium channel flower domain containing 1
chr12_-_110486348 1.99 ENST00000547573.1
ENST00000546651.2
ENST00000551185.2
chromosome 12 open reading frame 76
chr1_-_156217822 1.98 ENST00000368270.1
progestin and adipoQ receptor family member VI
chr4_-_153700864 1.96 ENST00000304337.2
tigger transposable element derived 4

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
2.2 6.6 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
2.0 5.9 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
1.8 7.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.7 5.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.7 5.0 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
1.5 4.6 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
1.3 5.3 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
1.3 5.3 GO:0002432 granuloma formation(GO:0002432)
1.2 3.7 GO:0070121 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
1.1 8.0 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
1.1 3.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
1.1 12.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.1 9.8 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.1 5.4 GO:0032425 positive regulation of mismatch repair(GO:0032425)
1.1 4.3 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.0 5.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.9 2.7 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.9 4.5 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.8 9.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.8 2.4 GO:0015680 intracellular copper ion transport(GO:0015680)
0.8 3.2 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.8 11.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.7 2.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.7 3.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.7 5.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.7 2.7 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.6 1.9 GO:0014016 neuroblast differentiation(GO:0014016)
0.6 1.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.6 3.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.6 2.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6 12.0 GO:0035641 locomotory exploration behavior(GO:0035641)
0.6 2.4 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.6 2.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.6 0.6 GO:0022900 electron transport chain(GO:0022900)
0.6 19.2 GO:0002021 response to dietary excess(GO:0002021)
0.6 5.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.6 2.8 GO:0098502 DNA dephosphorylation(GO:0098502)
0.6 3.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.5 5.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.5 2.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.5 1.9 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.4 11.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.4 7.9 GO:0015886 heme transport(GO:0015886)
0.4 4.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4 3.6 GO:0018094 protein polyglycylation(GO:0018094)
0.4 2.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.4 1.1 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.4 3.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.3 1.9 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 7.1 GO:0051014 actin filament severing(GO:0051014)
0.3 4.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 2.6 GO:0050957 equilibrioception(GO:0050957)
0.2 2.5 GO:0097338 response to clozapine(GO:0097338)
0.2 2.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 8.4 GO:0034389 lipid particle organization(GO:0034389)
0.2 2.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2 4.0 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 2.3 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.2 1.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 1.6 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.6 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 1.1 GO:0061009 common bile duct development(GO:0061009)
0.2 1.1 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 3.7 GO:1901978 mitochondrial fragmentation involved in apoptotic process(GO:0043653) positive regulation of cell cycle checkpoint(GO:1901978)
0.2 1.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 8.7 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 1.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.9 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 4.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.2 0.6 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 2.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 7.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 5.8 GO:0044458 motile cilium assembly(GO:0044458)
0.2 0.9 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 1.7 GO:0048318 axial mesoderm development(GO:0048318)
0.2 1.3 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 2.8 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 0.3 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 2.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 1.9 GO:0005513 detection of calcium ion(GO:0005513)
0.2 1.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 1.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 9.5 GO:0006298 mismatch repair(GO:0006298)
0.1 0.7 GO:0015862 uridine transport(GO:0015862)
0.1 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 1.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 3.3 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 2.3 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 2.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.9 GO:0048511 rhythmic process(GO:0048511)
0.1 1.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 7.3 GO:0006739 NADP metabolic process(GO:0006739)
0.1 1.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 2.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 3.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 2.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.4 GO:0061571 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 1.2 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 2.2 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.8 GO:0030238 male sex determination(GO:0030238)
0.1 10.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 4.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 5.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.7 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 3.9 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 2.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.5 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.5 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.1 15.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 1.8 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 5.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.6 GO:0048549 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1 0.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.2 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.1 1.3 GO:0061525 hindgut development(GO:0061525)
0.1 2.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 4.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 1.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 2.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.2 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 4.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.3 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.8 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 5.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 2.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.6 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.1 2.2 GO:0071801 regulation of podosome assembly(GO:0071801)
0.1 2.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.7 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 2.1 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 0.7 GO:0032264 IMP salvage(GO:0032264)
0.1 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.3 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 2.7 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.1 0.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 4.3 GO:0042246 tissue regeneration(GO:0042246)
0.1 2.3 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.1 0.9 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 6.9 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 3.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 3.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.5 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 5.6 GO:0046785 microtubule polymerization(GO:0046785)
0.1 0.2 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 4.1 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.2 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.6 GO:0043486 histone exchange(GO:0043486)
0.1 7.4 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 3.5 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 2.5 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 3.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.8 GO:0097320 membrane tubulation(GO:0097320)
0.0 1.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 1.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.6 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.4 GO:0031344 regulation of cell projection organization(GO:0031344)
0.0 0.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0048670 regulation of collateral sprouting(GO:0048670) positive regulation of collateral sprouting(GO:0048672)
0.0 4.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.0 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 1.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.0 GO:0007035 vacuolar acidification(GO:0007035)
0.0 1.4 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.0 2.6 GO:0032418 lysosome localization(GO:0032418)
0.0 1.6 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.7 GO:0032526 response to retinoic acid(GO:0032526)
0.0 8.7 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 1.4 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 3.3 GO:0071426 ribonucleoprotein complex export from nucleus(GO:0071426)
0.0 0.7 GO:0021591 ventricular system development(GO:0021591)
0.0 2.1 GO:0042308 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
0.0 2.4 GO:0060996 dendritic spine development(GO:0060996)
0.0 0.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.6 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.5 GO:0001975 response to amphetamine(GO:0001975)
0.0 1.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0009749 response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.7 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.3 GO:0008038 neuron recognition(GO:0008038)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.1 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.8 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.8 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 1.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 3.4 GO:0007411 axon guidance(GO:0007411)
0.0 1.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 1.7 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.2 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.3 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.2 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:1902636 kinociliary basal body(GO:1902636)
1.2 3.7 GO:0044609 DBIRD complex(GO:0044609)
1.2 7.3 GO:0097149 centralspindlin complex(GO:0097149)
1.1 4.6 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.9 19.4 GO:0036038 MKS complex(GO:0036038)
0.9 7.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.7 6.6 GO:1990812 growth cone filopodium(GO:1990812)
0.7 11.8 GO:0033010 paranodal junction(GO:0033010)
0.6 9.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.5 1.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.4 1.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.4 7.1 GO:0097427 microtubule bundle(GO:0097427)
0.4 1.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.4 3.2 GO:0043196 varicosity(GO:0043196)
0.4 7.1 GO:0032059 bleb(GO:0032059)
0.3 1.4 GO:1990423 RZZ complex(GO:1990423)
0.3 4.1 GO:0005577 fibrinogen complex(GO:0005577)
0.3 4.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 4.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 5.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 4.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 1.0 GO:0043291 RAVE complex(GO:0043291)
0.2 5.5 GO:0035102 PRC1 complex(GO:0035102)
0.2 3.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.2 0.9 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 1.2 GO:0036156 inner dynein arm(GO:0036156)
0.2 5.6 GO:0005915 zonula adherens(GO:0005915)
0.2 3.0 GO:0034464 BBSome(GO:0034464)
0.2 1.0 GO:1990031 pinceau fiber(GO:1990031)
0.2 6.9 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.5 GO:0016272 prefoldin complex(GO:0016272)
0.2 5.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 4.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.0 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 4.6 GO:0036020 endolysosome membrane(GO:0036020)
0.2 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.2 5.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 10.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.0 GO:0016342 catenin complex(GO:0016342)
0.1 2.0 GO:0042555 MCM complex(GO:0042555)
0.1 4.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.0 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 4.2 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 3.7 GO:0002080 acrosomal membrane(GO:0002080)
0.1 11.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.0 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 3.1 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 3.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 2.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 8.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 9.9 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 0.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 18.7 GO:0005802 trans-Golgi network(GO:0005802)
0.1 4.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.3 GO:0001741 XY body(GO:0001741)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 2.4 GO:0005921 gap junction(GO:0005921)
0.1 2.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 3.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726) nuclear stress granule(GO:0097165)
0.0 1.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 6.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0032797 SMN complex(GO:0032797)
0.0 0.5 GO:0016589 NURF complex(GO:0016589)
0.0 3.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0097346 INO80-type complex(GO:0097346)
0.0 4.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 6.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 7.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.2 GO:0002102 podosome(GO:0002102)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 12.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 3.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.5 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.0 GO:0097224 sperm connecting piece(GO:0097224)
0.0 1.9 GO:0005938 cell cortex(GO:0005938)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)
0.0 1.3 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
1.5 9.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.5 4.5 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
1.3 6.7 GO:0002046 opsin binding(GO:0002046)
1.0 3.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.9 5.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.9 2.7 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.8 3.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.8 7.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.7 3.6 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.7 7.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.7 2.8 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.7 2.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.7 5.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.6 2.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.6 3.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.5 6.9 GO:1901612 cardiolipin binding(GO:1901612)
0.5 1.9 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.5 13.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 1.8 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.4 2.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.4 3.3 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.4 1.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.4 12.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 5.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.3 1.9 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 4.8 GO:0015232 heme transporter activity(GO:0015232)
0.3 0.3 GO:0045142 triplex DNA binding(GO:0045142)
0.3 6.6 GO:0048156 tau protein binding(GO:0048156)
0.3 6.0 GO:0005522 profilin binding(GO:0005522)
0.3 3.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 4.5 GO:0045503 dynein light chain binding(GO:0045503)
0.3 2.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 1.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 0.6 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.2 0.6 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.2 1.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 3.0 GO:0034452 dynactin binding(GO:0034452)
0.2 3.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 2.0 GO:0004645 phosphorylase activity(GO:0004645)
0.2 3.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 3.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 2.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)
0.2 0.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 3.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 0.6 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.2 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 5.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 7.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.1 4.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.1 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 0.4 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 4.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.5 GO:0046625 sphingolipid binding(GO:0046625)
0.1 2.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 16.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 1.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 3.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 4.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 5.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 3.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 4.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 10.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.5 GO:0016417 S-acyltransferase activity(GO:0016417)
0.1 3.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 4.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 2.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 17.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 2.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 3.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 4.3 GO:0030507 spectrin binding(GO:0030507)
0.1 1.3 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 5.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 4.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 11.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 1.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.2 GO:0071949 FAD binding(GO:0071949)
0.0 4.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 6.2 GO:0005496 steroid binding(GO:0005496)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 1.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 4.9 GO:0003823 antigen binding(GO:0003823)
0.0 2.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 11.4 GO:0015631 tubulin binding(GO:0015631)
0.0 2.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 4.8 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 5.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.1 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 2.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.9 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 9.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 11.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 11.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 11.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 8.1 PID AURORA B PATHWAY Aurora B signaling
0.1 4.6 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.3 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 5.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 4.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 3.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.5 5.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 13.5 REACTOME KINESINS Genes involved in Kinesins
0.3 3.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 4.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 4.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 10.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 6.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 7.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 17.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 2.9 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 9.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 4.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 3.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 3.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 7.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 5.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 3.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 3.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.2 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.1 2.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 4.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 7.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 3.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 6.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.3 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 1.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 4.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 2.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 4.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes