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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RFX7_RFX4_RFX1

Z-value: 2.37

Motif logo

Transcription factors associated with RFX7_RFX4_RFX1

Gene Symbol Gene ID Gene Info
ENSG00000181827.10 regulatory factor X7
ENSG00000111783.8 regulatory factor X4
ENSG00000132005.4 regulatory factor X1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX7hg19_v2_chr15_-_56535464_56535521-0.835.1e-06Click!
RFX1hg19_v2_chr19_-_14117074_141171410.741.7e-04Click!
RFX4hg19_v2_chr12_+_106994905_1069949540.426.4e-02Click!

Activity profile of RFX7_RFX4_RFX1 motif

Sorted Z-values of RFX7_RFX4_RFX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51014345 31.87 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
Josephin domain containing 2
chr19_-_51014460 23.56 ENST00000595669.1
Josephin domain containing 2
chr19_-_51014588 14.58 ENST00000598418.1
Josephin domain containing 2
chr19_-_50316517 13.61 ENST00000313777.4
ENST00000445575.2
fuzzy planar cell polarity protein
chr19_+_55888186 11.99 ENST00000291934.3
transmembrane protein 190
chr19_-_50316423 11.12 ENST00000528094.1
ENST00000526575.1
fuzzy planar cell polarity protein
chr19_-_55791058 10.06 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_-_50316489 9.70 ENST00000533418.1
fuzzy planar cell polarity protein
chr19_+_507299 8.49 ENST00000359315.5
tubulin polyglutamylase complex subunit 1
chr11_-_6426635 8.04 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_+_55996316 7.79 ENST00000205194.4
N-acetyltransferase 14 (GCN5-related, putative)
chr17_+_73642315 7.00 ENST00000556126.2
small integral membrane protein 6
chrX_-_153095813 6.31 ENST00000544474.1
PDZ domain containing 4
chr17_+_73642486 6.30 ENST00000579469.1
small integral membrane protein 6
chr10_+_70980051 6.17 ENST00000354624.5
ENST00000395086.2
hexokinase domain containing 1
chr19_+_55996543 6.17 ENST00000591590.1
N-acetyltransferase 14 (GCN5-related, putative)
chr22_-_50970919 6.12 ENST00000329363.4
ENST00000437588.1
outer dense fiber of sperm tails 3B
chr19_-_40324767 5.70 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_-_55791431 5.64 ENST00000593263.1
ENST00000376343.3
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_+_55996565 5.49 ENST00000587400.1
N-acetyltransferase 14 (GCN5-related, putative)
chr19_+_48972459 5.33 ENST00000427476.1
cytohesin 2
chr12_-_76478686 5.30 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr19_-_41220957 5.22 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
aarF domain containing kinase 4
chr4_-_2420357 5.06 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
zinc finger, FYVE domain containing 28
chr22_-_23484246 4.87 ENST00000216036.4
rhabdoid tumor deletion region gene 1
chr19_-_41220540 4.78 ENST00000594490.1
aarF domain containing kinase 4
chr9_-_138391692 4.17 ENST00000429260.2
chromosome 9 open reading frame 116
chr16_-_30773372 4.12 ENST00000545825.1
ENST00000541260.1
chromosome 16 open reading frame 93
chr19_-_40324255 4.07 ENST00000593685.1
ENST00000600611.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr20_+_306221 4.03 ENST00000342665.2
SRY (sex determining region Y)-box 12
chr12_+_48577366 3.91 ENST00000316554.3
chromosome 12 open reading frame 68
chr19_-_55791540 3.84 ENST00000433386.2
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr20_+_48807351 3.78 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chrX_-_48693955 3.77 ENST00000218230.5
proprotein convertase subtilisin/kexin type 1 inhibitor
chr17_+_42977122 3.75 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr16_+_24550857 3.62 ENST00000568015.1
retinoblastoma binding protein 6
chr12_-_76478417 3.58 ENST00000552342.1
nucleosome assembly protein 1-like 1
chr20_+_306177 3.57 ENST00000544632.1
SRY (sex determining region Y)-box 12
chr2_+_219187871 3.57 ENST00000258362.3
paroxysmal nonkinesigenic dyskinesia
chr6_-_32908792 3.45 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr9_-_4666421 3.42 ENST00000381895.5
spermatogenesis associated 6-like
chr19_+_19639704 3.33 ENST00000514277.4
YjeF N-terminal domain containing 3
chr7_-_105221898 3.33 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EF-hand calcium binding domain 10
chr6_+_89790490 3.27 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr22_-_50970566 3.27 ENST00000405135.1
ENST00000401779.1
outer dense fiber of sperm tails 3B
chr4_+_176986978 3.22 ENST00000508596.1
ENST00000393643.2
WD repeat domain 17
chr12_+_53693466 3.21 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr1_+_45140360 3.12 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
chromosome 1 open reading frame 228
chr19_+_19639670 3.11 ENST00000436027.5
YjeF N-terminal domain containing 3
chr19_-_55791563 3.10 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr8_-_144623595 3.04 ENST00000262577.5
zinc finger CCCH-type containing 3
chr11_-_64885111 3.04 ENST00000528598.1
ENST00000310597.4
zinc finger, HIT-type containing 2
chr22_-_50970506 3.03 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr17_+_17876127 3.03 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr16_-_67700594 3.02 ENST00000602644.1
ENST00000243878.4
enkurin domain containing 1
chr19_+_48972265 3.00 ENST00000452733.2
cytohesin 2
chr16_-_67450325 3.00 ENST00000348579.2
zinc finger, DHHC-type containing 1
chr17_+_78010428 2.97 ENST00000397545.4
ENST00000374877.3
ENST00000269318.5
ENST00000374876.4
ENST00000576033.1
ENST00000574099.1
coiled-coil domain containing 40
chr20_+_17550489 2.96 ENST00000246069.7
destrin (actin depolymerizing factor)
chr17_+_16284104 2.92 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
ubiquitin B
chr19_-_59084922 2.89 ENST00000215057.2
ENST00000599369.1
myeloid zinc finger 1
chr16_-_29875057 2.76 ENST00000219789.6
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr5_+_176873789 2.74 ENST00000323249.3
ENST00000502922.1
proline rich 7 (synaptic)
chr8_+_144451039 2.73 ENST00000289013.6
rhophilin, Rho GTPase binding protein 1
chr12_-_113658892 2.68 ENST00000299732.2
ENST00000416617.2
IQ motif containing D
chr12_+_53693812 2.66 ENST00000549488.1
chromosome 12 open reading frame 10
chr2_+_170550944 2.61 ENST00000359744.3
ENST00000438838.1
ENST00000438710.1
ENST00000449906.1
ENST00000498202.2
ENST00000272797.4
phosphatase, orphan 2
kelch-like family member 23
chr14_+_96858433 2.58 ENST00000267584.4
adenylate kinase 7
chr17_+_45908974 2.56 ENST00000269025.4
leucine rich repeat containing 46
chr19_+_16308711 2.53 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
adaptor-related protein complex 1, mu 1 subunit
chr12_+_111051902 2.53 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
tectonic family member 1
chr9_-_4666337 2.50 ENST00000381890.5
spermatogenesis associated 6-like
chr6_+_89790459 2.44 ENST00000369472.1
proline-rich nuclear receptor coactivator 1
chr8_-_11324273 2.43 ENST00000284486.4
family with sequence similarity 167, member A
chr1_+_46972668 2.38 ENST00000371956.4
ENST00000360032.3
diencephalon/mesencephalon homeobox 1
chr6_-_32908765 2.35 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr12_-_76478446 2.34 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chr14_+_105957402 2.32 ENST00000421892.1
ENST00000334656.7
ENST00000451719.1
ENST00000392522.3
ENST00000392523.4
ENST00000354560.6
ENST00000450383.1
chromosome 14 open reading frame 80
chrX_-_23926004 2.29 ENST00000379226.4
ENST00000379220.3
apolipoprotein O
chr16_-_72127550 2.25 ENST00000268483.3
thioredoxin-like 4B
chr17_+_2264983 2.24 ENST00000574650.1
small G protein signaling modulator 2
chr22_+_35776354 2.20 ENST00000412893.1
heme oxygenase (decycling) 1
chr22_+_45809560 2.19 ENST00000342894.3
ENST00000538017.1
RIB43A domain with coiled-coils 2
chr2_-_62081148 2.19 ENST00000404929.1
family with sequence similarity 161, member A
chr19_-_45953983 2.17 ENST00000592083.1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chrX_-_153095945 2.16 ENST00000164640.4
PDZ domain containing 4
chr1_+_174968564 2.13 ENST00000426793.1
calcyclin binding protein
chr12_+_47473369 2.11 ENST00000546455.1
PC-esterase domain containing 1B
chr22_+_35776828 2.11 ENST00000216117.8
heme oxygenase (decycling) 1
chr10_+_15001430 2.07 ENST00000407572.1
meiosis/spermiogenesis associated 1
chr3_+_52350335 2.05 ENST00000420323.2
dynein, axonemal, heavy chain 1
chr12_+_49687425 2.04 ENST00000257860.4
peripherin
chr2_-_62081254 2.02 ENST00000405894.3
family with sequence similarity 161, member A
chr16_+_72127670 2.01 ENST00000536867.1
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr12_+_113587558 1.99 ENST00000335621.6
coiled-coil domain containing 42B
chr2_+_26785409 1.98 ENST00000329615.3
ENST00000409392.1
chromosome 2 open reading frame 70
chr11_-_559377 1.95 ENST00000486629.1
chromosome 11 open reading frame 35
chr19_-_46974741 1.93 ENST00000313683.10
ENST00000602246.1
paraneoplastic Ma antigen family-like 1
chr1_-_167905225 1.92 ENST00000367846.4
mitochondrial pyruvate carrier 2
chr1_-_235814048 1.92 ENST00000450593.1
ENST00000366598.4
guanine nucleotide binding protein (G protein), gamma 4
chr11_+_74660278 1.90 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr4_+_176987131 1.85 ENST00000280190.4
WD repeat domain 17
chr10_+_118608998 1.84 ENST00000409522.1
ENST00000341276.5
ENST00000512864.2
enolase family member 4
chr19_-_11545920 1.80 ENST00000356392.4
ENST00000591179.1
coiled-coil domain containing 151
chr19_+_50321528 1.80 ENST00000312865.6
ENST00000595185.1
ENST00000538643.1
mediator complex subunit 25
chr11_+_60681346 1.76 ENST00000227525.3
transmembrane protein 109
chr2_-_27498186 1.75 ENST00000447008.2
solute carrier family 30 (zinc transporter), member 3
chr16_-_29479154 1.73 ENST00000549950.1
Uncharacterized protein
chr19_-_46974664 1.72 ENST00000438932.2
paraneoplastic Ma antigen family-like 1
chr16_+_2059872 1.72 ENST00000567649.1
neuropeptide W
chr12_-_58329819 1.71 ENST00000551421.1
RP11-620J15.3
chr16_+_20912075 1.67 ENST00000219168.4
LYR motif containing 1
chr22_-_39268308 1.63 ENST00000407418.3
chromobox homolog 6
chr7_+_12726474 1.63 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ADP-ribosylation factor-like 4A
chr2_-_74781061 1.62 ENST00000264094.3
ENST00000393937.2
ENST00000409986.1
lysyl oxidase-like 3
chr2_-_242088850 1.61 ENST00000358649.4
ENST00000452907.1
ENST00000403638.3
ENST00000539818.1
ENST00000415234.1
ENST00000234040.4
PAS domain containing serine/threonine kinase
chr12_-_113658826 1.61 ENST00000546692.1
IQ motif containing D
chr20_+_17550691 1.61 ENST00000474024.1
destrin (actin depolymerizing factor)
chr5_-_7851260 1.59 ENST00000509627.1
chromosome 5 open reading frame 49
chr21_-_47738112 1.58 ENST00000417060.1
chromosome 21 open reading frame 58
chr3_-_157823839 1.58 ENST00000425436.3
ENST00000389589.4
ENST00000441443.2
short stature homeobox 2
chr7_-_138666053 1.56 ENST00000440172.1
ENST00000422774.1
KIAA1549
chr5_-_54529415 1.55 ENST00000282572.4
cyclin O
chr12_-_76478386 1.53 ENST00000535020.2
nucleosome assembly protein 1-like 1
chr17_-_73874654 1.50 ENST00000254816.2
tripartite motif containing 47
chr16_-_776431 1.50 ENST00000293889.6
coiled-coil domain containing 78
chr10_-_22292675 1.49 ENST00000376946.1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr9_+_138391805 1.49 ENST00000371785.1
mitochondrial ribosomal protein S2
chr17_+_42733730 1.47 ENST00000359945.3
ENST00000425535.1
chromosome 17 open reading frame 104
chr16_+_69458428 1.45 ENST00000512062.1
ENST00000307892.8
cytochrome b5 type B (outer mitochondrial membrane)
chr17_-_16256718 1.45 ENST00000476243.1
ENST00000299736.4
centromere protein V
chr21_-_44846999 1.45 ENST00000270162.6
salt-inducible kinase 1
chr6_-_76072719 1.44 ENST00000370020.1
filamin A interacting protein 1
chr11_+_450255 1.43 ENST00000308020.5
phosphatidylserine synthase 2
chr19_-_44079611 1.42 ENST00000594107.1
ENST00000543982.1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr10_-_14590644 1.41 ENST00000378470.1
family with sequence similarity 107, member B
chr4_+_153457404 1.41 ENST00000604157.1
ENST00000594836.1
microRNA 4453
chr21_-_47743719 1.41 ENST00000397680.1
ENST00000445935.1
ENST00000397685.4
ENST00000397682.3
ENST00000291691.7
chromosome 21 open reading frame 58
chr12_+_14927270 1.41 ENST00000544848.1
H2A histone family, member J
chr17_+_48585745 1.41 ENST00000323776.5
MYCBP associated protein
chr19_-_1490398 1.41 ENST00000588671.1
ENST00000300954.5
proprotein convertase subtilisin/kexin type 4
chr16_+_80574854 1.40 ENST00000305904.6
ENST00000568035.1
dynein, light chain, roadblock-type 2
chr8_+_86089460 1.40 ENST00000418930.2
E2F transcription factor 5, p130-binding
chr14_+_105992906 1.39 ENST00000392519.2
transmembrane protein 121
chr9_-_130477912 1.39 ENST00000543175.1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chrX_-_100662881 1.38 ENST00000218516.3
galactosidase, alpha
chr7_-_156433195 1.38 ENST00000333319.6
chromosome 7 open reading frame 13
chr3_+_51705222 1.38 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
testis expressed 264
chr15_-_101142401 1.37 ENST00000314742.8
lines homolog (Drosophila)
chr11_-_47736896 1.37 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
ATP/GTP binding protein-like 2
chr17_+_48585794 1.36 ENST00000576179.1
ENST00000419930.1
MYCBP associated protein
chr16_+_69458537 1.35 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
cytochrome b5 type B (outer mitochondrial membrane)
chr14_+_74111578 1.32 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
dynein, axonemal, light chain 1
chrX_-_154688276 1.32 ENST00000369445.2
coagulation factor VIII-associated 3
chr7_+_12726623 1.31 ENST00000439721.1
ADP-ribosylation factor-like 4A
chr15_-_85197501 1.31 ENST00000434634.2
WD repeat domain 73
chr19_-_40971667 1.30 ENST00000263368.4
biliverdin reductase B (flavin reductase (NADPH))
chr16_+_56691606 1.30 ENST00000334350.6
metallothionein 1F
chr17_+_48585958 1.30 ENST00000436259.2
MYCBP associated protein
chr14_+_105452094 1.28 ENST00000551606.1
ENST00000547315.1
chromosome 14 open reading frame 79
chr17_+_16284399 1.28 ENST00000535788.1
ubiquitin B
chr12_-_71551868 1.27 ENST00000247829.3
tetraspanin 8
chr7_-_27219849 1.26 ENST00000396344.4
homeobox A10
chr8_+_145162629 1.25 ENST00000323662.8
KIAA1875
chr5_+_68485433 1.25 ENST00000502689.1
centromere protein H
chr1_+_161068179 1.25 ENST00000368011.4
ENST00000392192.2
kelch domain containing 9
chr11_-_70507901 1.25 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SH3 and multiple ankyrin repeat domains 2
chr16_+_19467772 1.24 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
transmembrane channel-like 5
chr19_+_54705025 1.24 ENST00000441429.1
ribosomal protein S9
chr13_+_21141270 1.24 ENST00000319980.6
ENST00000537103.1
ENST00000389373.3
intraflagellar transport 88 homolog (Chlamydomonas)
chr2_-_190044480 1.24 ENST00000374866.3
collagen, type V, alpha 2
chr16_-_54963026 1.23 ENST00000560208.1
ENST00000557792.1
colorectal neoplasia differentially expressed (non-protein coding)
chr20_+_62492566 1.23 ENST00000369916.3
abhydrolase domain containing 16B
chr17_-_17494972 1.22 ENST00000435340.2
ENST00000255389.5
ENST00000395781.2
phosphatidylethanolamine N-methyltransferase
chr11_+_537494 1.22 ENST00000270115.7
leucine rich repeat containing 56
chr11_+_133938820 1.22 ENST00000299106.4
ENST00000529443.2
junctional adhesion molecule 3
chr12_-_107168696 1.21 ENST00000551505.1
Uncharacterized protein
chr17_+_17380294 1.21 ENST00000268711.3
ENST00000580462.1
mediator complex subunit 9
chr16_+_699319 1.20 ENST00000549091.1
ENST00000293879.4
WD repeat domain 90
chr12_-_71551652 1.19 ENST00000546561.1
tetraspanin 8
chr6_+_31707725 1.19 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
mutS homolog 5
chr10_+_94352956 1.19 ENST00000260731.3
kinesin family member 11
chr16_-_325910 1.18 ENST00000359740.5
ENST00000316163.5
ENST00000431291.2
ENST00000397770.3
ENST00000397768.3
regulator of G-protein signaling 11
chrX_+_154611749 1.17 ENST00000369505.3
coagulation factor VIII-associated 2
chr19_+_41856816 1.17 ENST00000539627.1
transmembrane protein 91
chr19_+_54704990 1.16 ENST00000391753.2
ribosomal protein S9
chr19_+_38880695 1.16 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr4_+_15004165 1.16 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
cytoplasmic polyadenylation element binding protein 2
chrX_+_154114635 1.16 ENST00000369446.2
coagulation factor VIII-associated 1
chr7_-_100239132 1.14 ENST00000223051.3
ENST00000431692.1
transferrin receptor 2
chr12_+_105724613 1.14 ENST00000549934.2
chromosome 12 open reading frame 75
chr11_-_71791435 1.14 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
nuclear mitotic apparatus protein 1
chr6_+_112408768 1.14 ENST00000368656.2
ENST00000604268.1
family with sequence similarity 229, member B
chr22_-_32555275 1.14 ENST00000382097.3
chromosome 22 open reading frame 42
chr15_-_56757329 1.14 ENST00000260453.3
meiosis-specific nuclear structural 1
chr7_-_7679633 1.13 ENST00000401447.1
replication protein A3, 14kDa
chr2_+_95537248 1.13 ENST00000427593.2
tektin 4
chr15_+_74610894 1.13 ENST00000558821.1
ENST00000268082.4
coiled-coil domain containing 33
chr16_+_20912382 1.13 ENST00000396052.2
LYR motif containing 1
chr12_+_49297899 1.12 ENST00000552942.1
ENST00000320516.4
coiled-coil domain containing 65

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 34.4 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
2.7 8.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
1.9 5.8 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
1.2 3.6 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.1 4.3 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
1.0 4.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.7 4.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.7 2.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.7 7.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.7 3.3 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.6 1.8 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.6 7.0 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.6 4.5 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.5 1.6 GO:0032203 telomere formation via telomerase(GO:0032203)
0.5 5.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.5 2.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.5 1.4 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.4 1.8 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.4 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 3.0 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.4 1.5 GO:2000213 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.4 1.4 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.4 2.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.3 0.7 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.3 6.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.3 1.0 GO:0039022 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.3 1.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.3 1.2 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.3 1.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.3 4.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 4.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.3 1.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 1.6 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.3 2.4 GO:0008343 adult feeding behavior(GO:0008343)
0.3 0.8 GO:0015680 intracellular copper ion transport(GO:0015680)
0.3 2.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 0.2 GO:0018307 enzyme active site formation(GO:0018307)
0.2 1.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 1.0 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.2 7.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 0.7 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.2 0.7 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.2 0.2 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.2 1.1 GO:0061009 common bile duct development(GO:0061009)
0.2 0.6 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 2.6 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.2 0.4 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.2 1.0 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 2.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.2 4.6 GO:0002021 response to dietary excess(GO:0002021)
0.2 0.6 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.2 1.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 1.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.6 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.2 1.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 2.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 0.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 1.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 0.6 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.2 2.3 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 6.5 GO:0006739 NADP metabolic process(GO:0006739)
0.2 1.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 0.5 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.2 0.5 GO:0006106 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate catabolic process(GO:0006533)
0.2 2.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.5 GO:0006173 dADP biosynthetic process(GO:0006173)
0.2 0.5 GO:0031247 actin rod assembly(GO:0031247)
0.2 0.8 GO:0007228 signal transduction downstream of smoothened(GO:0007227) positive regulation of hh target transcription factor activity(GO:0007228)
0.2 0.5 GO:0006186 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.2 1.7 GO:0016139 glycoside catabolic process(GO:0016139)
0.2 0.8 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2 0.5 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 0.5 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 70.6 GO:0016579 protein deubiquitination(GO:0016579)
0.1 6.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.9 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 1.3 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.1 1.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 1.2 GO:0051026 chiasma assembly(GO:0051026)
0.1 1.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.9 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 20.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.5 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.4 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.5 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 8.4 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.0 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.0 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.7 GO:0021997 neural plate axis specification(GO:0021997)
0.1 2.5 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 2.0 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 2.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 2.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.5 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.4 GO:0048318 axial mesoderm development(GO:0048318)
0.1 0.6 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.6 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.9 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.3 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.1 3.6 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 2.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.3 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 1.0 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.1 0.2 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 1.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 10.6 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.2 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 1.7 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.1 1.3 GO:0015886 heme transport(GO:0015886)
0.1 2.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.3 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.2 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 0.5 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.2 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.6 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.7 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 1.8 GO:0060065 uterus development(GO:0060065)
0.1 0.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.1 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.9 GO:0070986 left/right axis specification(GO:0070986)
0.1 3.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 1.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.9 GO:0006012 galactose metabolic process(GO:0006012)
0.0 2.2 GO:0042407 cristae formation(GO:0042407)
0.0 5.3 GO:0021510 spinal cord development(GO:0021510)
0.0 1.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 2.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 2.6 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.4 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.7 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 1.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 1.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 1.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 3.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.5 GO:0046689 response to mercury ion(GO:0046689)
0.0 2.4 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.4 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 2.3 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 1.2 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.7 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:0014060 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811) epinephrine secretion(GO:0048242)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.6 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 1.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 9.1 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 2.1 GO:0061053 somite development(GO:0061053)
0.0 0.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 1.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.3 GO:0031344 regulation of cell projection organization(GO:0031344)
0.0 0.9 GO:0042339 keratan sulfate biosynthetic process(GO:0018146) keratan sulfate metabolic process(GO:0042339)
0.0 1.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.8 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 6.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0018210 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 2.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 2.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.5 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.1 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.1 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.3 GO:0006818 hydrogen transport(GO:0006818) proton transport(GO:0015992)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.2 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 1.3 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.1 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.3 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.7 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 12.0 GO:0002079 inner acrosomal membrane(GO:0002079)
0.8 8.0 GO:1990812 growth cone filopodium(GO:1990812)
0.5 2.7 GO:0036156 inner dynein arm(GO:0036156)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.4 3.6 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.4 1.5 GO:1990075 periciliary membrane compartment(GO:1990075)
0.3 1.0 GO:0044609 DBIRD complex(GO:0044609)
0.3 4.3 GO:0005901 caveola(GO:0005901)
0.3 0.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.3 0.8 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.3 0.6 GO:0002177 manchette(GO:0002177)
0.3 2.2 GO:0061617 MICOS complex(GO:0061617)
0.3 5.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 2.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 1.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 1.7 GO:0005787 signal peptidase complex(GO:0005787)
0.2 1.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 3.3 GO:0030990 intraciliary transport particle(GO:0030990)
0.2 2.1 GO:0036157 outer dynein arm(GO:0036157)
0.2 3.4 GO:0036038 MKS complex(GO:0036038)
0.2 0.5 GO:0001534 radial spoke(GO:0001534)
0.2 2.7 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0098536 deuterosome(GO:0098536)
0.1 3.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:0055087 Ski complex(GO:0055087)
0.1 0.9 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 5.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 4.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.8 GO:0070695 FHF complex(GO:0070695)
0.1 1.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 3.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 0.7 GO:0005869 dynactin complex(GO:0005869)
0.1 1.4 GO:0005883 neurofilament(GO:0005883)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 17.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.2 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.6 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.2 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 4.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.6 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 8.6 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.0 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.5 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 1.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0070187 telosome(GO:0070187)
0.0 0.4 GO:0005840 ribosome(GO:0005840)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 6.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 4.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.2 GO:0016020 membrane(GO:0016020)
0.0 5.7 GO:0042995 cell projection(GO:0042995)
0.0 2.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 3.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 2.4 GO:0005902 microvillus(GO:0005902)
0.0 2.1 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 3.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 6.1 GO:0005938 cell cortex(GO:0005938)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.8 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.6 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
1.2 3.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.1 4.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 2.8 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.9 2.8 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.8 7.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.7 6.3 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.7 0.7 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.6 2.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.5 4.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.5 3.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.5 67.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.4 1.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.4 3.6 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.4 1.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.4 8.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 1.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.4 8.2 GO:0048156 tau protein binding(GO:0048156)
0.3 1.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 0.9 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.3 1.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 2.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 5.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 1.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 1.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 1.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 3.5 GO:0015925 galactosidase activity(GO:0015925)
0.2 0.7 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.2 2.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 2.1 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.6 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.2 0.8 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 0.6 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2 1.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.5 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 0.8 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.2 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 1.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 1.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 0.5 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 5.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 2.7 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 0.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 0.5 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.2 1.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 11.8 GO:0043621 protein self-association(GO:0043621)
0.1 3.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0005119 smoothened binding(GO:0005119)
0.1 0.7 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 1.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 1.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.1 9.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 14.1 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 6.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 3.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 2.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.9 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.3 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 1.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 1.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.7 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.8 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348) beta-glucosidase activity(GO:0008422)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 1.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 1.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.5 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 12.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.7 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.9 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 3.3 GO:0046332 SMAD binding(GO:0046332)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 2.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 1.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 2.7 GO:0020037 heme binding(GO:0020037)
0.0 0.7 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.0 PID ARF 3PATHWAY Arf1 pathway
0.2 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 11.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 ST GAQ PATHWAY G alpha q Pathway
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 0.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.0 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 2.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 2.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 1.3 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 3.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.8 REACTOME KINESINS Genes involved in Kinesins
0.0 2.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.5 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 4.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 3.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 3.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs