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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for RREB1
Z-value: 2.20
Motif logo
Transcription factors associated with RREB1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RREB1
|
ENSG00000124782.15 | ras responsive element binding protein 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RREB1 | hg19_v2_chr6_+_7107999_7108054 | 0.95 | 7.3e-11 | Click! |
Activity profile of RREB1 motif
Sorted Z-values of RREB1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_153538292 | 16.02 |
ENST00000497140.1
ENST00000368708.3 |
S100A2
|
S100 calcium binding protein A2 |
| chr19_+_35609380 | 15.74 |
ENST00000604621.1
|
FXYD3
|
FXYD domain containing ion transport regulator 3 |
| chr19_-_51456344 | 9.56 |
ENST00000336334.3
ENST00000593428.1 |
KLK5
|
kallikrein-related peptidase 5 |
| chr17_-_39216344 | 9.43 |
ENST00000391418.2
|
KRTAP2-3
|
keratin associated protein 2-3 |
| chr9_-_21994344 | 9.03 |
ENST00000530628.2
ENST00000361570.3 |
CDKN2A
|
cyclin-dependent kinase inhibitor 2A |
| chr17_-_39677971 | 8.90 |
ENST00000393976.2
|
KRT15
|
keratin 15 |
| chr1_-_153363452 | 8.39 |
ENST00000368732.1
ENST00000368733.3 |
S100A8
|
S100 calcium binding protein A8 |
| chr19_-_51456321 | 8.01 |
ENST00000391809.2
|
KLK5
|
kallikrein-related peptidase 5 |
| chr9_-_21994597 | 7.99 |
ENST00000579755.1
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A |
| chr1_-_17307173 | 7.30 |
ENST00000438542.1
ENST00000375535.3 |
MFAP2
|
microfibrillar-associated protein 2 |
| chr16_-_4588469 | 7.18 |
ENST00000588381.1
ENST00000563332.2 |
CDIP1
|
cell death-inducing p53 target 1 |
| chr16_-_4588762 | 6.71 |
ENST00000562334.1
ENST00000562579.1 ENST00000567695.1 ENST00000563507.1 |
CDIP1
|
cell death-inducing p53 target 1 |
| chr16_+_68771128 | 6.41 |
ENST00000261769.5
ENST00000422392.2 |
CDH1
|
cadherin 1, type 1, E-cadherin (epithelial) |
| chr2_+_234104079 | 6.08 |
ENST00000417661.1
|
INPP5D
|
inositol polyphosphate-5-phosphatase, 145kDa |
| chr19_-_51456198 | 6.04 |
ENST00000594846.1
|
KLK5
|
kallikrein-related peptidase 5 |
| chr16_-_4588391 | 5.52 |
ENST00000586728.1
|
CDIP1
|
cell death-inducing p53 target 1 |
| chr1_+_61548374 | 5.37 |
ENST00000485903.2
ENST00000371185.2 ENST00000371184.2 |
NFIA
|
nuclear factor I/A |
| chr8_-_75233563 | 5.36 |
ENST00000342232.4
|
JPH1
|
junctophilin 1 |
| chr8_+_26149274 | 5.26 |
ENST00000522535.1
|
PPP2R2A
|
protein phosphatase 2, regulatory subunit B, alpha |
| chr16_-_4588822 | 5.26 |
ENST00000564828.1
|
CDIP1
|
cell death-inducing p53 target 1 |
| chr2_+_192542879 | 5.23 |
ENST00000409510.1
|
NABP1
|
nucleic acid binding protein 1 |
| chr6_+_43112037 | 4.81 |
ENST00000473339.1
|
PTK7
|
protein tyrosine kinase 7 |
| chr22_-_44258360 | 4.69 |
ENST00000330884.4
ENST00000249130.5 |
SULT4A1
|
sulfotransferase family 4A, member 1 |
| chr19_-_51471381 | 4.58 |
ENST00000594641.1
|
KLK6
|
kallikrein-related peptidase 6 |
| chr10_+_115438920 | 4.52 |
ENST00000429617.1
ENST00000369331.4 |
CASP7
|
caspase 7, apoptosis-related cysteine peptidase |
| chr12_-_95044309 | 4.36 |
ENST00000261226.4
|
TMCC3
|
transmembrane and coiled-coil domain family 3 |
| chr6_+_7541808 | 4.28 |
ENST00000379802.3
|
DSP
|
desmoplakin |
| chr6_+_7541845 | 4.18 |
ENST00000418664.2
|
DSP
|
desmoplakin |
| chr8_+_95653840 | 4.10 |
ENST00000520385.1
|
ESRP1
|
epithelial splicing regulatory protein 1 |
| chrX_+_102585124 | 4.09 |
ENST00000332431.4
ENST00000372666.1 |
TCEAL7
|
transcription elongation factor A (SII)-like 7 |
| chr18_+_33877654 | 4.09 |
ENST00000257209.4
ENST00000445677.1 ENST00000590592.1 ENST00000359247.4 |
FHOD3
|
formin homology 2 domain containing 3 |
| chr1_-_228604328 | 4.04 |
ENST00000355586.4
ENST00000366698.2 ENST00000520264.1 ENST00000479800.1 ENST00000295033.3 |
TRIM17
|
tripartite motif containing 17 |
| chr2_+_192543153 | 3.90 |
ENST00000425611.2
|
NABP1
|
nucleic acid binding protein 1 |
| chr7_-_92465868 | 3.89 |
ENST00000424848.2
|
CDK6
|
cyclin-dependent kinase 6 |
| chr2_+_192542850 | 3.87 |
ENST00000410026.2
|
NABP1
|
nucleic acid binding protein 1 |
| chr17_+_7788104 | 3.83 |
ENST00000380358.4
|
CHD3
|
chromodomain helicase DNA binding protein 3 |
| chr16_+_57679859 | 3.82 |
ENST00000569494.1
ENST00000566169.1 |
GPR56
|
G protein-coupled receptor 56 |
| chr2_-_230786378 | 3.81 |
ENST00000430954.1
|
TRIP12
|
thyroid hormone receptor interactor 12 |
| chr19_-_37406923 | 3.79 |
ENST00000520965.1
|
ZNF829
|
zinc finger protein 829 |
| chr5_+_150591678 | 3.67 |
ENST00000523466.1
|
GM2A
|
GM2 ganglioside activator |
| chr4_-_87374283 | 3.66 |
ENST00000361569.2
|
MAPK10
|
mitogen-activated protein kinase 10 |
| chr19_-_19051927 | 3.65 |
ENST00000600077.1
|
HOMER3
|
homer homolog 3 (Drosophila) |
| chr13_-_52026730 | 3.62 |
ENST00000420668.2
|
INTS6
|
integrator complex subunit 6 |
| chr13_-_74708372 | 3.49 |
ENST00000377666.4
|
KLF12
|
Kruppel-like factor 12 |
| chr20_+_1115821 | 3.49 |
ENST00000435720.1
|
PSMF1
|
proteasome (prosome, macropain) inhibitor subunit 1 (PI31) |
| chr3_+_41241596 | 3.40 |
ENST00000450969.1
|
CTNNB1
|
catenin (cadherin-associated protein), beta 1, 88kDa |
| chr4_-_56412713 | 3.32 |
ENST00000435527.2
|
CLOCK
|
clock circadian regulator |
| chr6_+_149638876 | 3.28 |
ENST00000392282.1
|
TAB2
|
TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| chr16_+_57679945 | 3.26 |
ENST00000568157.1
|
GPR56
|
G protein-coupled receptor 56 |
| chr22_+_41487711 | 3.21 |
ENST00000263253.7
|
EP300
|
E1A binding protein p300 |
| chr17_-_6459802 | 3.20 |
ENST00000262483.8
|
PITPNM3
|
PITPNM family member 3 |
| chr3_-_18466026 | 3.15 |
ENST00000417717.2
|
SATB1
|
SATB homeobox 1 |
| chr2_+_219745020 | 3.13 |
ENST00000258411.3
|
WNT10A
|
wingless-type MMTV integration site family, member 10A |
| chr13_-_52027134 | 3.10 |
ENST00000311234.4
ENST00000425000.1 ENST00000463928.1 ENST00000442263.3 ENST00000398119.2 |
INTS6
|
integrator complex subunit 6 |
| chr4_-_77996032 | 3.10 |
ENST00000505609.1
|
CCNI
|
cyclin I |
| chr10_+_13628921 | 3.09 |
ENST00000378572.3
|
PRPF18
|
pre-mRNA processing factor 18 |
| chr3_+_192958914 | 3.08 |
ENST00000264735.2
ENST00000602513.1 |
HRASLS
|
HRAS-like suppressor |
| chr5_+_138629628 | 3.05 |
ENST00000508689.1
ENST00000514528.1 |
MATR3
|
matrin 3 |
| chr22_+_38321840 | 3.04 |
ENST00000454685.1
|
MICALL1
|
MICAL-like 1 |
| chr11_+_128562372 | 3.03 |
ENST00000344954.6
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr11_-_118789613 | 3.03 |
ENST00000532899.1
|
BCL9L
|
B-cell CLL/lymphoma 9-like |
| chr16_+_27325202 | 2.98 |
ENST00000395762.2
ENST00000562142.1 ENST00000561742.1 ENST00000543915.2 ENST00000449195.1 ENST00000380922.3 ENST00000563002.1 |
IL4R
|
interleukin 4 receptor |
| chr6_-_86352982 | 2.98 |
ENST00000369622.3
|
SYNCRIP
|
synaptotagmin binding, cytoplasmic RNA interacting protein |
| chr4_-_100484825 | 2.95 |
ENST00000273962.3
ENST00000514547.1 ENST00000455368.2 |
TRMT10A
|
tRNA methyltransferase 10 homolog A (S. cerevisiae) |
| chr12_+_57522692 | 2.93 |
ENST00000554174.1
|
LRP1
|
low density lipoprotein receptor-related protein 1 |
| chr12_+_96588279 | 2.91 |
ENST00000552142.1
|
ELK3
|
ELK3, ETS-domain protein (SRF accessory protein 2) |
| chr5_+_138629337 | 2.86 |
ENST00000394805.3
ENST00000512876.1 ENST00000513678.1 |
MATR3
|
matrin 3 |
| chr12_+_6554021 | 2.82 |
ENST00000266557.3
|
CD27
|
CD27 molecule |
| chr11_+_46403194 | 2.75 |
ENST00000395569.4
ENST00000395566.4 |
MDK
|
midkine (neurite growth-promoting factor 2) |
| chr10_+_127661942 | 2.72 |
ENST00000417114.1
ENST00000445510.1 ENST00000368691.1 |
FANK1
|
fibronectin type III and ankyrin repeat domains 1 |
| chr11_+_46403303 | 2.71 |
ENST00000407067.1
ENST00000395565.1 |
MDK
|
midkine (neurite growth-promoting factor 2) |
| chr17_-_6459768 | 2.66 |
ENST00000421306.3
|
PITPNM3
|
PITPNM family member 3 |
| chr1_-_228604454 | 2.64 |
ENST00000456946.2
|
TRIM17
|
tripartite motif containing 17 |
| chr11_+_34073269 | 2.61 |
ENST00000389645.3
|
CAPRIN1
|
cell cycle associated protein 1 |
| chr3_+_41240925 | 2.60 |
ENST00000396183.3
ENST00000349496.5 ENST00000453024.1 |
CTNNB1
|
catenin (cadherin-associated protein), beta 1, 88kDa |
| chr1_-_201346761 | 2.57 |
ENST00000455702.1
ENST00000422165.1 ENST00000367318.5 ENST00000367320.2 ENST00000438742.1 ENST00000412633.1 ENST00000458432.2 ENST00000421663.2 ENST00000367322.1 ENST00000509001.1 |
TNNT2
|
troponin T type 2 (cardiac) |
| chr5_+_125758865 | 2.55 |
ENST00000542322.1
ENST00000544396.1 |
GRAMD3
|
GRAM domain containing 3 |
| chr2_+_28974531 | 2.53 |
ENST00000420282.1
|
PPP1CB
|
protein phosphatase 1, catalytic subunit, beta isozyme |
| chr8_-_142011036 | 2.51 |
ENST00000520892.1
|
PTK2
|
protein tyrosine kinase 2 |
| chr16_+_57680043 | 2.51 |
ENST00000569154.1
|
GPR56
|
G protein-coupled receptor 56 |
| chr5_+_138629389 | 2.43 |
ENST00000504045.1
ENST00000504311.1 ENST00000502499.1 |
MATR3
|
matrin 3 |
| chr17_-_4642429 | 2.41 |
ENST00000573123.1
|
CXCL16
|
chemokine (C-X-C motif) ligand 16 |
| chr12_-_120687948 | 2.40 |
ENST00000458477.2
|
PXN
|
paxillin |
| chr2_+_54684327 | 2.38 |
ENST00000389980.3
|
SPTBN1
|
spectrin, beta, non-erythrocytic 1 |
| chr11_-_35547151 | 2.34 |
ENST00000378878.3
ENST00000529303.1 ENST00000278360.3 |
PAMR1
|
peptidase domain containing associated with muscle regeneration 1 |
| chr6_-_86353510 | 2.32 |
ENST00000444272.1
|
SYNCRIP
|
synaptotagmin binding, cytoplasmic RNA interacting protein |
| chr5_+_125758813 | 2.32 |
ENST00000285689.3
ENST00000515200.1 |
GRAMD3
|
GRAM domain containing 3 |
| chr18_+_72166564 | 2.31 |
ENST00000583216.1
ENST00000581912.1 ENST00000582589.1 |
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family) |
| chr5_-_124080203 | 2.29 |
ENST00000504926.1
|
ZNF608
|
zinc finger protein 608 |
| chr20_+_33462745 | 2.29 |
ENST00000488172.1
|
ACSS2
|
acyl-CoA synthetase short-chain family member 2 |
| chr5_-_124084493 | 2.29 |
ENST00000509799.1
|
ZNF608
|
zinc finger protein 608 |
| chr17_+_48611853 | 2.28 |
ENST00000507709.1
ENST00000515126.1 ENST00000507467.1 |
EPN3
|
epsin 3 |
| chr13_-_108867846 | 2.24 |
ENST00000442234.1
|
LIG4
|
ligase IV, DNA, ATP-dependent |
| chr8_+_94929969 | 2.23 |
ENST00000517764.1
|
PDP1
|
pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| chr1_-_113392399 | 2.23 |
ENST00000449572.2
ENST00000433505.1 |
RP11-426L16.8
|
RP11-426L16.8 |
| chr15_+_63481668 | 2.22 |
ENST00000321437.4
ENST00000559006.1 ENST00000448330.2 |
RAB8B
|
RAB8B, member RAS oncogene family |
| chr12_-_49351148 | 2.20 |
ENST00000398092.4
ENST00000539611.1 |
RP11-302B13.5
ARF3
|
ADP-ribosylation factor 3 ADP-ribosylation factor 3 |
| chr12_-_6716569 | 2.19 |
ENST00000544040.1
ENST00000545942.1 |
CHD4
|
chromodomain helicase DNA binding protein 4 |
| chr17_-_58499766 | 2.17 |
ENST00000588898.1
|
USP32
|
ubiquitin specific peptidase 32 |
| chr19_-_6720686 | 2.16 |
ENST00000245907.6
|
C3
|
complement component 3 |
| chr5_-_142065223 | 2.14 |
ENST00000378046.1
|
FGF1
|
fibroblast growth factor 1 (acidic) |
| chr17_-_79817091 | 2.14 |
ENST00000570907.1
|
P4HB
|
prolyl 4-hydroxylase, beta polypeptide |
| chr19_-_19051993 | 2.14 |
ENST00000594794.1
ENST00000355887.6 ENST00000392351.3 ENST00000596482.1 |
HOMER3
|
homer homolog 3 (Drosophila) |
| chr9_+_35906176 | 2.13 |
ENST00000354323.2
|
HRCT1
|
histidine rich carboxyl terminus 1 |
| chr7_+_75932863 | 2.13 |
ENST00000429938.1
|
HSPB1
|
heat shock 27kDa protein 1 |
| chr19_-_51471362 | 2.12 |
ENST00000376853.4
ENST00000424910.2 |
KLK6
|
kallikrein-related peptidase 6 |
| chr6_+_37321823 | 2.12 |
ENST00000487950.1
ENST00000469731.1 |
RNF8
|
ring finger protein 8, E3 ubiquitin protein ligase |
| chr7_-_102213030 | 2.07 |
ENST00000511313.1
ENST00000513438.1 ENST00000513506.1 |
POLR2J3
|
polymerase (RNA) II (DNA directed) polypeptide J3 |
| chr2_+_106468204 | 2.06 |
ENST00000425756.1
ENST00000393349.2 |
NCK2
|
NCK adaptor protein 2 |
| chr17_-_76732928 | 2.06 |
ENST00000589768.1
|
CYTH1
|
cytohesin 1 |
| chr1_+_61548225 | 2.03 |
ENST00000371187.3
|
NFIA
|
nuclear factor I/A |
| chr3_+_140660634 | 2.02 |
ENST00000446041.2
ENST00000507429.1 ENST00000324194.6 |
SLC25A36
|
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36 |
| chr12_-_6716534 | 2.02 |
ENST00000544484.1
ENST00000309577.6 ENST00000357008.2 |
CHD4
|
chromodomain helicase DNA binding protein 4 |
| chr2_+_223289208 | 2.01 |
ENST00000321276.7
|
SGPP2
|
sphingosine-1-phosphate phosphatase 2 |
| chr3_+_140660743 | 1.98 |
ENST00000453248.2
|
SLC25A36
|
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36 |
| chr1_+_43148059 | 1.97 |
ENST00000321358.7
ENST00000332220.6 |
YBX1
|
Y box binding protein 1 |
| chr21_-_34915123 | 1.97 |
ENST00000438059.1
|
GART
|
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| chr12_+_62654119 | 1.96 |
ENST00000353364.3
ENST00000549523.1 ENST00000280377.5 |
USP15
|
ubiquitin specific peptidase 15 |
| chr1_+_43148625 | 1.96 |
ENST00000436427.1
|
YBX1
|
Y box binding protein 1 |
| chr10_+_13628933 | 1.95 |
ENST00000417658.1
ENST00000320054.4 |
PRPF18
|
pre-mRNA processing factor 18 |
| chr6_+_168227611 | 1.95 |
ENST00000344191.4
ENST00000351017.4 ENST00000392108.3 ENST00000366806.2 ENST00000392112.1 ENST00000400824.4 ENST00000447894.2 ENST00000400822.3 |
MLLT4
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| chr4_-_100485183 | 1.94 |
ENST00000394876.2
|
TRMT10A
|
tRNA methyltransferase 10 homolog A (S. cerevisiae) |
| chr6_+_7107830 | 1.93 |
ENST00000379933.3
|
RREB1
|
ras responsive element binding protein 1 |
| chr6_-_13486369 | 1.91 |
ENST00000558378.1
|
AL583828.1
|
AL583828.1 |
| chr2_-_122247879 | 1.90 |
ENST00000545861.1
|
CLASP1
|
cytoplasmic linker associated protein 1 |
| chr19_-_57352064 | 1.90 |
ENST00000326441.9
ENST00000593695.1 ENST00000599577.1 ENST00000594389.1 ENST00000423103.2 ENST00000598410.1 ENST00000593711.1 ENST00000391708.3 ENST00000221722.5 ENST00000599935.1 |
PEG3
ZIM2
|
paternally expressed 3 zinc finger, imprinted 2 |
| chr17_-_39728303 | 1.89 |
ENST00000588431.1
ENST00000246662.4 |
KRT9
|
keratin 9 |
| chr10_+_70091812 | 1.87 |
ENST00000265866.7
|
HNRNPH3
|
heterogeneous nuclear ribonucleoprotein H3 (2H9) |
| chr2_-_67442409 | 1.86 |
ENST00000414404.1
ENST00000433133.1 |
AC078941.1
|
AC078941.1 |
| chr22_-_44258280 | 1.85 |
ENST00000540422.1
|
SULT4A1
|
sulfotransferase family 4A, member 1 |
| chr2_-_85637459 | 1.84 |
ENST00000409921.1
|
CAPG
|
capping protein (actin filament), gelsolin-like |
| chr8_+_144816303 | 1.83 |
ENST00000533004.1
|
FAM83H-AS1
|
FAM83H antisense RNA 1 (head to head) |
| chr3_-_71632894 | 1.83 |
ENST00000493089.1
|
FOXP1
|
forkhead box P1 |
| chr3_+_41240986 | 1.83 |
ENST00000396185.3
|
CTNNB1
|
catenin (cadherin-associated protein), beta 1, 88kDa |
| chr11_+_69455855 | 1.82 |
ENST00000227507.2
ENST00000536559.1 |
CCND1
|
cyclin D1 |
| chr11_-_57089671 | 1.82 |
ENST00000532437.1
|
TNKS1BP1
|
tankyrase 1 binding protein 1, 182kDa |
| chr17_+_48796905 | 1.80 |
ENST00000505658.1
ENST00000393227.2 ENST00000240304.1 ENST00000311571.3 ENST00000505619.1 ENST00000544170.1 ENST00000510984.1 |
LUC7L3
|
LUC7-like 3 (S. cerevisiae) |
| chr11_-_129872712 | 1.80 |
ENST00000358825.5
ENST00000360871.3 ENST00000528746.1 |
PRDM10
|
PR domain containing 10 |
| chr10_+_70091847 | 1.80 |
ENST00000441000.2
ENST00000354695.5 |
HNRNPH3
|
heterogeneous nuclear ribonucleoprotein H3 (2H9) |
| chr4_+_56719782 | 1.77 |
ENST00000381295.2
ENST00000346134.7 ENST00000349598.6 |
EXOC1
|
exocyst complex component 1 |
| chr19_+_3366547 | 1.77 |
ENST00000341919.3
ENST00000590282.1 ENST00000443272.2 |
NFIC
|
nuclear factor I/C (CCAAT-binding transcription factor) |
| chr3_+_184032919 | 1.75 |
ENST00000427845.1
ENST00000342981.4 ENST00000319274.6 |
EIF4G1
|
eukaryotic translation initiation factor 4 gamma, 1 |
| chr11_+_66886717 | 1.72 |
ENST00000398645.2
|
KDM2A
|
lysine (K)-specific demethylase 2A |
| chr8_+_28748099 | 1.71 |
ENST00000519047.1
|
HMBOX1
|
homeobox containing 1 |
| chr1_-_113249734 | 1.71 |
ENST00000484054.3
ENST00000369636.2 ENST00000369637.1 ENST00000285735.2 ENST00000369638.2 |
RHOC
|
ras homolog family member C |
| chr19_-_12405606 | 1.70 |
ENST00000356109.5
|
ZNF44
|
zinc finger protein 44 |
| chr2_+_48757278 | 1.70 |
ENST00000404752.1
ENST00000406226.1 |
STON1
|
stonin 1 |
| chr1_-_113249678 | 1.69 |
ENST00000369633.2
ENST00000425265.2 ENST00000369632.2 ENST00000436685.2 |
RHOC
|
ras homolog family member C |
| chr7_+_91570165 | 1.68 |
ENST00000356239.3
ENST00000359028.2 ENST00000358100.2 |
AKAP9
|
A kinase (PRKA) anchor protein 9 |
| chr17_+_35849937 | 1.62 |
ENST00000394389.4
|
DUSP14
|
dual specificity phosphatase 14 |
| chr17_+_42385927 | 1.60 |
ENST00000426726.3
ENST00000590941.1 ENST00000225441.7 |
RUNDC3A
|
RUN domain containing 3A |
| chr18_-_21242729 | 1.60 |
ENST00000585908.2
|
ANKRD29
|
ankyrin repeat domain 29 |
| chr1_+_46668994 | 1.58 |
ENST00000371980.3
|
LURAP1
|
leucine rich adaptor protein 1 |
| chr12_+_96588368 | 1.58 |
ENST00000547860.1
|
ELK3
|
ELK3, ETS-domain protein (SRF accessory protein 2) |
| chr15_+_67390920 | 1.57 |
ENST00000559092.1
ENST00000560175.1 |
SMAD3
|
SMAD family member 3 |
| chr7_-_51384451 | 1.55 |
ENST00000441453.1
ENST00000265136.7 ENST00000395542.2 ENST00000395540.2 |
COBL
|
cordon-bleu WH2 repeat protein |
| chr11_+_20044375 | 1.55 |
ENST00000525322.1
ENST00000530408.1 |
NAV2
|
neuron navigator 2 |
| chr2_-_241836298 | 1.54 |
ENST00000414499.1
|
C2orf54
|
chromosome 2 open reading frame 54 |
| chr21_-_36259445 | 1.53 |
ENST00000399240.1
|
RUNX1
|
runt-related transcription factor 1 |
| chr20_+_58179582 | 1.53 |
ENST00000371015.1
ENST00000395639.4 |
PHACTR3
|
phosphatase and actin regulator 3 |
| chr22_-_36357671 | 1.52 |
ENST00000408983.2
|
RBFOX2
|
RNA binding protein, fox-1 homolog (C. elegans) 2 |
| chr16_-_3285144 | 1.52 |
ENST00000431561.3
ENST00000396870.4 |
ZNF200
|
zinc finger protein 200 |
| chr7_-_150721570 | 1.52 |
ENST00000377974.2
ENST00000444312.1 ENST00000605938.1 ENST00000605952.1 |
ATG9B
|
autophagy related 9B |
| chr22_-_44894178 | 1.52 |
ENST00000341255.3
|
LDOC1L
|
leucine zipper, down-regulated in cancer 1-like |
| chr2_-_241836244 | 1.49 |
ENST00000454476.2
|
C2orf54
|
chromosome 2 open reading frame 54 |
| chr12_-_123849374 | 1.49 |
ENST00000602398.1
ENST00000602750.1 |
SBNO1
|
strawberry notch homolog 1 (Drosophila) |
| chr12_+_861717 | 1.48 |
ENST00000535572.1
|
WNK1
|
WNK lysine deficient protein kinase 1 |
| chr11_-_85779971 | 1.47 |
ENST00000393346.3
|
PICALM
|
phosphatidylinositol binding clathrin assembly protein |
| chr11_-_35547277 | 1.46 |
ENST00000527605.1
|
PAMR1
|
peptidase domain containing associated with muscle regeneration 1 |
| chr5_-_133512654 | 1.46 |
ENST00000522552.1
|
SKP1
|
S-phase kinase-associated protein 1 |
| chr17_-_66453562 | 1.46 |
ENST00000262139.5
ENST00000546360.1 |
WIPI1
|
WD repeat domain, phosphoinositide interacting 1 |
| chr5_-_142065612 | 1.45 |
ENST00000360966.5
ENST00000411960.1 |
FGF1
|
fibroblast growth factor 1 (acidic) |
| chr17_-_62658186 | 1.44 |
ENST00000262435.9
|
SMURF2
|
SMAD specific E3 ubiquitin protein ligase 2 |
| chr11_+_111896320 | 1.44 |
ENST00000531306.1
ENST00000537636.1 |
DLAT
|
dihydrolipoamide S-acetyltransferase |
| chr18_+_72167096 | 1.44 |
ENST00000324301.8
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family) |
| chr10_-_71930222 | 1.44 |
ENST00000458634.2
ENST00000373239.2 ENST00000373242.2 ENST00000373241.4 |
SAR1A
|
SAR1 homolog A (S. cerevisiae) |
| chr6_-_34664612 | 1.44 |
ENST00000374023.3
ENST00000374026.3 |
C6orf106
|
chromosome 6 open reading frame 106 |
| chr21_-_47648665 | 1.43 |
ENST00000450351.1
ENST00000522411.1 ENST00000356396.4 ENST00000397728.3 ENST00000457828.2 |
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| chr17_-_7141490 | 1.43 |
ENST00000574236.1
ENST00000572789.1 |
PHF23
|
PHD finger protein 23 |
| chr11_+_46402744 | 1.41 |
ENST00000533952.1
|
MDK
|
midkine (neurite growth-promoting factor 2) |
| chr12_+_62654155 | 1.40 |
ENST00000312635.6
ENST00000393654.3 ENST00000549237.1 |
USP15
|
ubiquitin specific peptidase 15 |
| chr19_-_12405689 | 1.38 |
ENST00000355684.5
|
ZNF44
|
zinc finger protein 44 |
| chr19_+_10982189 | 1.38 |
ENST00000327064.4
ENST00000588947.1 |
CARM1
|
coactivator-associated arginine methyltransferase 1 |
| chr3_+_154797877 | 1.38 |
ENST00000462745.1
ENST00000493237.1 |
MME
|
membrane metallo-endopeptidase |
| chr11_-_96239990 | 1.35 |
ENST00000511243.2
|
JRKL-AS1
|
JRKL antisense RNA 1 |
| chr19_-_18653781 | 1.34 |
ENST00000596558.2
ENST00000453489.2 |
FKBP8
|
FK506 binding protein 8, 38kDa |
| chr1_-_21377383 | 1.34 |
ENST00000374935.3
|
EIF4G3
|
eukaryotic translation initiation factor 4 gamma, 3 |
| chr1_+_16083098 | 1.33 |
ENST00000496928.2
ENST00000508310.1 |
FBLIM1
|
filamin binding LIM protein 1 |
| chr20_-_45984401 | 1.30 |
ENST00000311275.7
|
ZMYND8
|
zinc finger, MYND-type containing 8 |
| chr3_-_55521323 | 1.30 |
ENST00000264634.4
|
WNT5A
|
wingless-type MMTV integration site family, member 5A |
| chr9_+_132934835 | 1.28 |
ENST00000372398.3
|
NCS1
|
neuronal calcium sensor 1 |
| chr1_-_160254913 | 1.28 |
ENST00000440949.3
ENST00000368072.5 ENST00000608310.1 ENST00000556710.1 |
PEX19
DCAF8
DCAF8
|
peroxisomal biogenesis factor 19 DDB1 and CUL4 associated factor 8 DDB1- and CUL4-associated factor 8 |
| chr12_+_96588143 | 1.26 |
ENST00000228741.3
ENST00000547249.1 |
ELK3
|
ELK3, ETS-domain protein (SRF accessory protein 2) |
| chr18_-_45456693 | 1.26 |
ENST00000587421.1
|
SMAD2
|
SMAD family member 2 |
| chr11_+_20044600 | 1.23 |
ENST00000311043.8
|
NAV2
|
neuron navigator 2 |
| chr2_-_230786619 | 1.22 |
ENST00000389045.3
ENST00000409677.1 |
TRIP12
|
thyroid hormone receptor interactor 12 |
| chr11_+_34073195 | 1.22 |
ENST00000341394.4
|
CAPRIN1
|
cell cycle associated protein 1 |
| chr19_-_15442701 | 1.21 |
ENST00000594841.1
ENST00000601941.1 |
BRD4
|
bromodomain containing 4 |
| chr16_+_1728305 | 1.21 |
ENST00000569765.1
|
HN1L
|
hematological and neurological expressed 1-like |
| chr21_+_34915337 | 1.21 |
ENST00000290239.6
ENST00000381692.2 ENST00000300278.4 ENST00000381679.4 |
SON
|
SON DNA binding protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of RREB1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.9 | 23.6 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
| 2.0 | 7.8 | GO:0007403 | glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) |
| 1.7 | 5.0 | GO:0071048 | nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048) |
| 1.4 | 17.0 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 1.3 | 4.0 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 1.2 | 6.1 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 1.1 | 6.9 | GO:0030421 | defecation(GO:0030421) |
| 0.8 | 8.5 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.8 | 3.4 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.8 | 9.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.8 | 7.3 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.8 | 3.2 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.7 | 2.2 | GO:0051102 | DNA ligation involved in DNA recombination(GO:0051102) |
| 0.7 | 4.4 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.7 | 2.2 | GO:0001798 | positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894) |
| 0.6 | 2.6 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 0.6 | 7.9 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
| 0.6 | 2.9 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.6 | 6.4 | GO:0071680 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 0.6 | 2.8 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.5 | 2.1 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.5 | 8.4 | GO:0032119 | sequestering of zinc ion(GO:0032119) |
| 0.5 | 4.5 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.5 | 3.0 | GO:0045626 | negative regulation of T-helper 1 cell differentiation(GO:0045626) |
| 0.5 | 1.5 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
| 0.5 | 1.9 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.5 | 4.2 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.5 | 1.4 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
| 0.4 | 3.3 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.4 | 1.7 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.4 | 6.1 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.4 | 2.4 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.4 | 3.9 | GO:0045656 | negative regulation of monocyte differentiation(GO:0045656) |
| 0.4 | 1.2 | GO:0060697 | positive regulation of phospholipid catabolic process(GO:0060697) |
| 0.4 | 1.5 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.4 | 2.2 | GO:0019541 | acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542) |
| 0.4 | 5.4 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 0.4 | 1.4 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.4 | 1.1 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.3 | 2.1 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.3 | 3.1 | GO:0021564 | vagus nerve development(GO:0021564) |
| 0.3 | 2.4 | GO:1902962 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.3 | 6.7 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.3 | 1.6 | GO:0001757 | somite specification(GO:0001757) |
| 0.3 | 3.7 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.3 | 0.9 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.3 | 2.4 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.3 | 4.0 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.3 | 1.4 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.3 | 4.5 | GO:0070141 | response to UV-A(GO:0070141) |
| 0.3 | 2.2 | GO:0051461 | positive regulation of corticotropin secretion(GO:0051461) |
| 0.3 | 1.5 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.3 | 1.3 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.3 | 5.3 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.2 | 2.1 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.2 | 4.5 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.2 | 24.7 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.2 | 1.4 | GO:0097210 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.2 | 1.1 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.2 | 1.6 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.2 | 6.7 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.2 | 1.1 | GO:0009912 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
| 0.2 | 5.8 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.2 | 2.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.2 | 3.1 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.2 | 0.8 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.2 | 5.2 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.2 | 4.7 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.2 | 5.7 | GO:0072189 | ureter development(GO:0072189) |
| 0.2 | 4.9 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.2 | 2.0 | GO:0006189 | brainstem development(GO:0003360) 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.2 | 1.8 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.2 | 1.5 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 4.5 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.1 | 13.2 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 1.7 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.1 | 3.0 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.1 | 1.3 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.1 | 2.4 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.1 | 5.9 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.1 | 6.5 | GO:0050427 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.1 | 0.8 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.1 | 14.1 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 1.9 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.1 | 1.5 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.1 | 0.2 | GO:0061056 | sclerotome development(GO:0061056) |
| 0.1 | 5.4 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.1 | 1.0 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 2.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.1 | 1.9 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 3.0 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 3.8 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 1.5 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 1.6 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.1 | 2.0 | GO:0006670 | sphingosine metabolic process(GO:0006670) |
| 0.1 | 1.2 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.1 | 1.3 | GO:0045046 | protein import into peroxisome membrane(GO:0045046) |
| 0.1 | 1.2 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 0.1 | 1.0 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.1 | 1.8 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 2.7 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 3.8 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.1 | 6.9 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 2.9 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.1 | 0.6 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 0.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 1.4 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 6.0 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.1 | 0.6 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.1 | 0.4 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.1 | 0.5 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 0.6 | GO:0055048 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.1 | 0.6 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.1 | 6.3 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 0.1 | 0.3 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.1 | 0.8 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.1 | 11.1 | GO:0031424 | keratinization(GO:0031424) |
| 0.1 | 1.0 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 3.3 | GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) |
| 0.0 | 0.3 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.0 | 0.4 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.0 | 0.3 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.0 | 0.5 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.0 | 0.2 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 0.0 | 3.6 | GO:1901799 | negative regulation of proteasomal protein catabolic process(GO:1901799) |
| 0.0 | 0.4 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.0 | 1.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.5 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.0 | 1.1 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 0.1 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 0.0 | 5.8 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.0 | 1.0 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 1.3 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 7.3 | GO:0043542 | endothelial cell migration(GO:0043542) |
| 0.0 | 1.0 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.4 | GO:0007512 | adult heart development(GO:0007512) |
| 0.0 | 0.2 | GO:0071484 | cellular response to light intensity(GO:0071484) |
| 0.0 | 0.1 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 0.2 | GO:0002414 | immunoglobulin transcytosis in epithelial cells(GO:0002414) |
| 0.0 | 1.4 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 2.2 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.1 | GO:0050894 | determination of affect(GO:0050894) |
| 0.0 | 1.1 | GO:0032922 | circadian regulation of gene expression(GO:0032922) |
| 0.0 | 1.0 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.6 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.0 | 1.4 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.0 | 1.7 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
| 0.0 | 1.3 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.0 | 4.9 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.0 | 0.6 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.0 | 0.7 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 0.2 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 0.3 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.0 | 0.9 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
| 0.0 | 0.5 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.0 | 1.1 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.3 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.0 | 0.1 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.0 | 7.3 | GO:0010608 | posttranscriptional regulation of gene expression(GO:0010608) |
| 0.0 | 4.0 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 0.2 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 23.6 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 2.2 | 24.7 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 1.6 | 13.0 | GO:0070876 | SOSS complex(GO:0070876) |
| 1.4 | 17.0 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 1.3 | 5.0 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 1.0 | 7.8 | GO:0070369 | Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.9 | 9.2 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.9 | 3.7 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.6 | 2.2 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.5 | 2.1 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.5 | 6.4 | GO:0016342 | catenin complex(GO:0016342) |
| 0.5 | 9.6 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.5 | 1.9 | GO:0031592 | centrosomal corona(GO:0031592) |
| 0.4 | 6.7 | GO:0032039 | integrator complex(GO:0032039) |
| 0.4 | 5.4 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.4 | 1.8 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.4 | 2.6 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.4 | 2.4 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.4 | 2.2 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.3 | 2.4 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.3 | 2.8 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.3 | 7.4 | GO:0030054 | cell junction(GO:0030054) |
| 0.2 | 2.2 | GO:0051286 | cell tip(GO:0051286) |
| 0.2 | 2.1 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.2 | 0.8 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.2 | 3.3 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.2 | 7.5 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.2 | 2.5 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.2 | 1.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.2 | 16.0 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 1.9 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 3.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 3.6 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.1 | 0.2 | GO:0031379 | RNA-directed RNA polymerase complex(GO:0031379) |
| 0.1 | 3.2 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 1.8 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 2.8 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 7.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 1.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 4.4 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.1 | 8.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 4.1 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 1.1 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 2.8 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 4.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 1.8 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.1 | 5.8 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.1 | 17.2 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.1 | 1.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 1.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 2.1 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 3.2 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 0.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.6 | GO:0055028 | cortical microtubule(GO:0055028) |
| 0.1 | 1.3 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.1 | 1.5 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 1.0 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 2.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.2 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.6 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.0 | 2.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 6.3 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 1.0 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 1.0 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 1.3 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.7 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 1.2 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 2.1 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 1.0 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 2.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 4.5 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 1.1 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 1.2 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 1.9 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 1.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 3.2 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 1.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 1.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 5.2 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
| 0.0 | 1.7 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 3.8 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.1 | GO:0036156 | inner dynein arm(GO:0036156) |
| 0.0 | 3.6 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.2 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.0 | 1.2 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 1.1 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.2 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 1.1 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 5.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 1.3 | 4.0 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 1.3 | 3.9 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 1.2 | 8.4 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 1.0 | 5.0 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 1.0 | 2.9 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 1.0 | 5.9 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.8 | 6.1 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.8 | 3.8 | GO:0102008 | cytosolic dipeptidase activity(GO:0102008) |
| 0.7 | 3.0 | GO:0004913 | interleukin-4 receptor activity(GO:0004913) |
| 0.7 | 2.2 | GO:0016418 | S-acetyltransferase activity(GO:0016418) |
| 0.7 | 17.0 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.7 | 8.5 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.6 | 2.3 | GO:1990175 | EH domain binding(GO:1990175) |
| 0.5 | 4.8 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.5 | 2.1 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.5 | 2.5 | GO:0050115 | myosin-light-chain-phosphatase activity(GO:0050115) |
| 0.5 | 2.0 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644) |
| 0.5 | 3.4 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.5 | 3.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.5 | 1.4 | GO:0004968 | gonadotropin-releasing hormone receptor activity(GO:0004968) |
| 0.4 | 5.9 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.4 | 7.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.4 | 1.1 | GO:0097158 | pre-mRNA intronic pyrimidine-rich binding(GO:0097158) |
| 0.3 | 4.0 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.3 | 1.3 | GO:1902379 | receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379) |
| 0.3 | 2.6 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.3 | 2.2 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.3 | 8.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.3 | 0.9 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.3 | 2.2 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.3 | 2.9 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.3 | 5.8 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.2 | 2.1 | GO:0019798 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.2 | 6.5 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.2 | 5.3 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.2 | 1.6 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.2 | 2.8 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.2 | 2.4 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.2 | 1.9 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.2 | 0.8 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.2 | 3.7 | GO:0016004 | phospholipase activator activity(GO:0016004) |
| 0.2 | 1.9 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.2 | 10.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.2 | 15.1 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.2 | 1.6 | GO:0010853 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.2 | 2.2 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.2 | 1.2 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.2 | 0.9 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 0.2 | 2.2 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.2 | 1.5 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.2 | 1.2 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.1 | 5.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.1 | 0.4 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.1 | 1.0 | GO:0043813 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 0.1 | 3.6 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 4.5 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.1 | 0.4 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 0.1 | 1.0 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 1.4 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
| 0.1 | 2.5 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 1.4 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.1 | 31.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 3.5 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 1.3 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.1 | 3.0 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.1 | 0.5 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 2.1 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 5.0 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 3.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 1.7 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 3.3 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 1.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 2.4 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 2.1 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 2.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 1.1 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 3.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 3.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 2.4 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.1 | 1.8 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 0.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.1 | 4.1 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.1 | GO:1904854 | proteasome core complex binding(GO:1904854) |
| 0.1 | 2.8 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 1.8 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 2.1 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 8.7 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 0.4 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 1.2 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 1.0 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.1 | 1.0 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 1.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 1.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 1.3 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.3 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 0.0 | 1.5 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.3 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.0 | 1.7 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 1.1 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.4 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 4.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 1.1 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.2 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.0 | 6.4 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.0 | 0.7 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 1.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 1.8 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.8 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 0.6 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 1.4 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 4.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 2.3 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 2.5 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 7.2 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 1.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 2.4 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.4 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 3.3 | GO:0008238 | exopeptidase activity(GO:0008238) |
| 0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.7 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) |
| 0.0 | 0.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 1.4 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 1.4 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 9.7 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.2 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 0.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 2.2 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.3 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 5.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.5 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 1.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 9.6 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.2 | GO:0019865 | immunoglobulin binding(GO:0019865) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 17.1 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.3 | 10.0 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.2 | 3.0 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.2 | 18.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.2 | 8.1 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.2 | 11.5 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.2 | 7.2 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.2 | 15.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 2.2 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 4.5 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 3.3 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.1 | 6.9 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 3.7 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.1 | 3.9 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 7.9 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 8.5 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 6.7 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 2.2 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 8.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 2.2 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 8.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 4.0 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 2.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 1.0 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 8.0 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 2.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 1.0 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 1.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 2.4 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 2.9 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 2.1 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 1.8 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 1.2 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 2.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.1 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 1.1 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 1.3 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.0 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 22.7 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.4 | 28.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.4 | 1.1 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.3 | 3.3 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.2 | 4.5 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.2 | 6.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.2 | 1.0 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.2 | 6.5 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 4.1 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.1 | 2.2 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.1 | 6.0 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 2.2 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 5.5 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 2.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.1 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.1 | 5.2 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 8.5 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 3.2 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 2.2 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.1 | 4.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 3.8 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 2.0 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 2.4 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 5.6 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.1 | 1.1 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 4.0 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 1.3 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 1.8 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 2.6 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 1.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 1.0 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.3 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.0 | 4.4 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 3.1 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.6 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 5.3 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.6 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 0.7 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 1.2 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.0 | 4.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.0 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 1.3 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |