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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for RUNX3_BCL11A
Z-value: 1.48
Motif logo
Transcription factors associated with RUNX3_BCL11A
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RUNX3
|
ENSG00000020633.14 | RUNX family transcription factor 3 |
|
BCL11A
|
ENSG00000119866.16 | BAF chromatin remodeling complex subunit BCL11A |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BCL11A | hg19_v2_chr2_-_60780546_60780566 | 0.96 | 5.3e-11 | Click! |
| RUNX3 | hg19_v2_chr1_-_25291475_25291511 | -0.95 | 1.9e-10 | Click! |
Activity profile of RUNX3_BCL11A motif
Sorted Z-values of RUNX3_BCL11A motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_+_45296391 | 10.24 |
ENST00000371436.6
ENST00000576263.1 |
RUNX2
|
runt-related transcription factor 2 |
| chr3_+_136676707 | 9.61 |
ENST00000329582.4
|
IL20RB
|
interleukin 20 receptor beta |
| chr3_+_136676851 | 9.13 |
ENST00000309741.5
|
IL20RB
|
interleukin 20 receptor beta |
| chr6_+_45296048 | 9.08 |
ENST00000465038.2
ENST00000352853.5 ENST00000541979.1 ENST00000371438.1 |
RUNX2
|
runt-related transcription factor 2 |
| chr17_-_39661849 | 5.96 |
ENST00000246635.3
ENST00000336861.3 ENST00000587544.1 ENST00000587435.1 |
KRT13
|
keratin 13 |
| chr17_-_7164410 | 5.74 |
ENST00000574070.1
|
CLDN7
|
claudin 7 |
| chr10_+_5566916 | 5.68 |
ENST00000315238.1
|
CALML3
|
calmodulin-like 3 |
| chr9_-_117853297 | 5.51 |
ENST00000542877.1
ENST00000537320.1 ENST00000341037.4 |
TNC
|
tenascin C |
| chr11_-_58345569 | 5.39 |
ENST00000528954.1
ENST00000528489.1 |
LPXN
|
leupaxin |
| chr1_-_39395165 | 4.67 |
ENST00000372985.3
|
RHBDL2
|
rhomboid, veinlet-like 2 (Drosophila) |
| chr1_+_209859510 | 4.47 |
ENST00000367028.2
ENST00000261465.1 |
HSD11B1
|
hydroxysteroid (11-beta) dehydrogenase 1 |
| chr3_+_189507460 | 4.21 |
ENST00000434928.1
|
TP63
|
tumor protein p63 |
| chr5_+_131409476 | 4.04 |
ENST00000296871.2
|
CSF2
|
colony stimulating factor 2 (granulocyte-macrophage) |
| chr3_+_189507523 | 3.96 |
ENST00000437221.1
ENST00000392463.2 ENST00000392461.3 ENST00000449992.1 ENST00000456148.1 |
TP63
|
tumor protein p63 |
| chr17_-_39661947 | 3.86 |
ENST00000590425.1
|
KRT13
|
keratin 13 |
| chr17_-_39674668 | 3.74 |
ENST00000393981.3
|
KRT15
|
keratin 15 |
| chr5_+_148206156 | 3.66 |
ENST00000305988.4
|
ADRB2
|
adrenoceptor beta 2, surface |
| chr5_-_138861926 | 3.59 |
ENST00000510817.1
|
TMEM173
|
transmembrane protein 173 |
| chr5_+_35856951 | 3.59 |
ENST00000303115.3
ENST00000343305.4 ENST00000506850.1 ENST00000511982.1 |
IL7R
|
interleukin 7 receptor |
| chr7_+_18535346 | 3.51 |
ENST00000405010.3
ENST00000406451.4 ENST00000428307.2 |
HDAC9
|
histone deacetylase 9 |
| chr5_-_39270725 | 3.43 |
ENST00000512138.1
ENST00000512982.1 ENST00000540520.1 |
FYB
|
FYN binding protein |
| chr3_-_99569821 | 3.43 |
ENST00000487087.1
|
FILIP1L
|
filamin A interacting protein 1-like |
| chr17_-_74533963 | 3.27 |
ENST00000293230.5
|
CYGB
|
cytoglobin |
| chr3_+_189349162 | 3.27 |
ENST00000264731.3
ENST00000382063.4 ENST00000418709.2 ENST00000320472.5 ENST00000392460.3 ENST00000440651.2 |
TP63
|
tumor protein p63 |
| chr20_+_44637526 | 3.23 |
ENST00000372330.3
|
MMP9
|
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| chr3_+_189507432 | 3.17 |
ENST00000354600.5
|
TP63
|
tumor protein p63 |
| chr4_+_106816592 | 3.06 |
ENST00000379987.2
ENST00000453617.2 ENST00000427316.2 ENST00000514622.1 ENST00000305572.8 |
NPNT
|
nephronectin |
| chr14_+_85996507 | 3.05 |
ENST00000554746.1
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr14_+_85996471 | 2.89 |
ENST00000330753.4
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr4_-_152147579 | 2.84 |
ENST00000304527.4
ENST00000455740.1 ENST00000424281.1 ENST00000409598.4 |
SH3D19
|
SH3 domain containing 19 |
| chr15_+_67390920 | 2.80 |
ENST00000559092.1
ENST00000560175.1 |
SMAD3
|
SMAD family member 3 |
| chr15_-_60695071 | 2.79 |
ENST00000557904.1
|
ANXA2
|
annexin A2 |
| chr15_+_49715449 | 2.75 |
ENST00000560979.1
|
FGF7
|
fibroblast growth factor 7 |
| chr6_+_144904334 | 2.74 |
ENST00000367526.4
|
UTRN
|
utrophin |
| chr11_-_118122996 | 2.68 |
ENST00000525386.1
ENST00000527472.1 ENST00000278949.4 |
MPZL3
|
myelin protein zero-like 3 |
| chr7_+_18535321 | 2.68 |
ENST00000413380.1
ENST00000430454.1 |
HDAC9
|
histone deacetylase 9 |
| chr19_+_56989485 | 2.68 |
ENST00000585445.1
ENST00000586091.1 ENST00000594783.1 ENST00000592146.1 ENST00000588158.1 ENST00000299997.4 ENST00000591797.1 |
ZNF667-AS1
|
ZNF667 antisense RNA 1 (head to head) |
| chrX_+_68048803 | 2.63 |
ENST00000204961.4
|
EFNB1
|
ephrin-B1 |
| chr19_-_42636617 | 2.56 |
ENST00000529067.1
ENST00000529952.1 ENST00000533720.1 ENST00000389341.5 ENST00000342301.4 |
POU2F2
|
POU class 2 homeobox 2 |
| chr14_-_85996332 | 2.53 |
ENST00000380722.1
|
RP11-497E19.1
|
RP11-497E19.1 |
| chr13_-_38172863 | 2.51 |
ENST00000541481.1
ENST00000379743.4 ENST00000379742.4 ENST00000379749.4 ENST00000541179.1 ENST00000379747.4 |
POSTN
|
periostin, osteoblast specific factor |
| chr6_+_15401075 | 2.31 |
ENST00000541660.1
|
JARID2
|
jumonji, AT rich interactive domain 2 |
| chr1_+_152486950 | 2.30 |
ENST00000368790.3
|
CRCT1
|
cysteine-rich C-terminal 1 |
| chr3_+_50126341 | 2.30 |
ENST00000347869.3
ENST00000469838.1 ENST00000404526.2 ENST00000441305.1 |
RBM5
|
RNA binding motif protein 5 |
| chr6_-_75912508 | 2.28 |
ENST00000416123.2
|
COL12A1
|
collagen, type XII, alpha 1 |
| chr2_+_173292059 | 2.19 |
ENST00000412899.1
ENST00000409532.1 |
ITGA6
|
integrin, alpha 6 |
| chr12_-_15114492 | 2.17 |
ENST00000541546.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr21_-_36421626 | 2.14 |
ENST00000300305.3
|
RUNX1
|
runt-related transcription factor 1 |
| chr7_+_70229899 | 2.12 |
ENST00000443672.1
|
AUTS2
|
autism susceptibility candidate 2 |
| chr12_-_15114191 | 2.07 |
ENST00000541380.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr5_-_39203093 | 2.07 |
ENST00000515010.1
|
FYB
|
FYN binding protein |
| chr4_-_57976544 | 2.05 |
ENST00000295666.4
ENST00000537922.1 |
IGFBP7
|
insulin-like growth factor binding protein 7 |
| chr21_-_36421401 | 2.04 |
ENST00000486278.2
|
RUNX1
|
runt-related transcription factor 1 |
| chr14_+_51955831 | 2.01 |
ENST00000356218.4
|
FRMD6
|
FERM domain containing 6 |
| chr2_+_173292390 | 1.88 |
ENST00000442250.1
ENST00000458358.1 ENST00000409080.1 |
ITGA6
|
integrin, alpha 6 |
| chr1_+_26872324 | 1.86 |
ENST00000531382.1
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| chr6_+_116692102 | 1.84 |
ENST00000359564.2
|
DSE
|
dermatan sulfate epimerase |
| chr19_-_49496557 | 1.83 |
ENST00000323798.3
ENST00000541188.1 ENST00000544287.1 ENST00000540532.1 ENST00000263276.6 |
GYS1
|
glycogen synthase 1 (muscle) |
| chr10_+_101419187 | 1.80 |
ENST00000370489.4
|
ENTPD7
|
ectonucleoside triphosphate diphosphohydrolase 7 |
| chr11_-_102826434 | 1.80 |
ENST00000340273.4
ENST00000260302.3 |
MMP13
|
matrix metallopeptidase 13 (collagenase 3) |
| chr11_+_35198243 | 1.77 |
ENST00000528455.1
|
CD44
|
CD44 molecule (Indian blood group) |
| chr1_-_153348067 | 1.74 |
ENST00000368737.3
|
S100A12
|
S100 calcium binding protein A12 |
| chr17_-_1532106 | 1.73 |
ENST00000301335.5
ENST00000382147.4 |
SLC43A2
|
solute carrier family 43 (amino acid system L transporter), member 2 |
| chr10_+_24738355 | 1.72 |
ENST00000307544.6
|
KIAA1217
|
KIAA1217 |
| chr1_-_175161890 | 1.69 |
ENST00000545251.2
ENST00000423313.1 |
KIAA0040
|
KIAA0040 |
| chr2_+_173292280 | 1.63 |
ENST00000264107.7
|
ITGA6
|
integrin, alpha 6 |
| chr3_+_156799587 | 1.63 |
ENST00000469196.1
|
RP11-6F2.5
|
RP11-6F2.5 |
| chr21_-_36421535 | 1.59 |
ENST00000416754.1
ENST00000437180.1 ENST00000455571.1 |
RUNX1
|
runt-related transcription factor 1 |
| chr7_-_84121858 | 1.59 |
ENST00000448879.1
|
SEMA3A
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| chr12_-_4754339 | 1.59 |
ENST00000228850.1
|
AKAP3
|
A kinase (PRKA) anchor protein 3 |
| chr6_+_63921399 | 1.59 |
ENST00000356170.3
|
FKBP1C
|
FK506 binding protein 1C |
| chr2_+_173292301 | 1.58 |
ENST00000264106.6
ENST00000375221.2 ENST00000343713.4 |
ITGA6
|
integrin, alpha 6 |
| chr1_+_196621156 | 1.57 |
ENST00000359637.2
|
CFH
|
complement factor H |
| chr3_-_71179699 | 1.57 |
ENST00000497355.1
|
FOXP1
|
forkhead box P1 |
| chr3_-_196014520 | 1.57 |
ENST00000441879.1
ENST00000292823.2 ENST00000411591.1 ENST00000431016.1 ENST00000443555.1 |
PCYT1A
|
phosphate cytidylyltransferase 1, choline, alpha |
| chr3_+_49977440 | 1.55 |
ENST00000442092.1
ENST00000266022.4 ENST00000443081.1 |
RBM6
|
RNA binding motif protein 6 |
| chr2_-_214016314 | 1.55 |
ENST00000434687.1
ENST00000374319.4 |
IKZF2
|
IKAROS family zinc finger 2 (Helios) |
| chr1_+_196621002 | 1.54 |
ENST00000367429.4
ENST00000439155.2 |
CFH
|
complement factor H |
| chr5_+_145316120 | 1.53 |
ENST00000359120.4
|
SH3RF2
|
SH3 domain containing ring finger 2 |
| chr16_+_82090028 | 1.53 |
ENST00000568090.1
|
HSD17B2
|
hydroxysteroid (17-beta) dehydrogenase 2 |
| chr13_-_46756351 | 1.51 |
ENST00000323076.2
|
LCP1
|
lymphocyte cytosolic protein 1 (L-plastin) |
| chr19_+_13135386 | 1.50 |
ENST00000360105.4
ENST00000588228.1 ENST00000591028.1 |
NFIX
|
nuclear factor I/X (CCAAT-binding transcription factor) |
| chr14_+_75988768 | 1.49 |
ENST00000286639.6
|
BATF
|
basic leucine zipper transcription factor, ATF-like |
| chr19_+_13135731 | 1.49 |
ENST00000587260.1
|
NFIX
|
nuclear factor I/X (CCAAT-binding transcription factor) |
| chr3_+_9944303 | 1.46 |
ENST00000421412.1
ENST00000295980.3 |
IL17RE
|
interleukin 17 receptor E |
| chr1_+_149553003 | 1.45 |
ENST00000369222.3
|
PPIAL4C
|
peptidylprolyl isomerase A (cyclophilin A)-like 4C |
| chr19_+_13135790 | 1.45 |
ENST00000358552.3
|
NFIX
|
nuclear factor I/X (CCAAT-binding transcription factor) |
| chr6_+_42847649 | 1.45 |
ENST00000424341.2
ENST00000602561.1 |
RPL7L1
|
ribosomal protein L7-like 1 |
| chr14_-_21493649 | 1.42 |
ENST00000553442.1
ENST00000555869.1 ENST00000556457.1 ENST00000397844.2 ENST00000554415.1 |
NDRG2
|
NDRG family member 2 |
| chr14_-_21493884 | 1.42 |
ENST00000556974.1
ENST00000554419.1 ENST00000298687.5 ENST00000397858.1 ENST00000360463.3 ENST00000350792.3 ENST00000397847.2 |
NDRG2
|
NDRG family member 2 |
| chr7_+_18330035 | 1.39 |
ENST00000413509.2
|
HDAC9
|
histone deacetylase 9 |
| chr1_+_89246647 | 1.38 |
ENST00000544045.1
|
PKN2
|
protein kinase N2 |
| chr2_+_33359687 | 1.37 |
ENST00000402934.1
ENST00000404525.1 ENST00000407925.1 |
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr11_-_94965667 | 1.35 |
ENST00000542176.1
ENST00000278499.2 |
SESN3
|
sestrin 3 |
| chr15_+_73976545 | 1.35 |
ENST00000318443.5
ENST00000537340.2 ENST00000318424.5 |
CD276
|
CD276 molecule |
| chr17_+_7462031 | 1.34 |
ENST00000380535.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr12_-_120662499 | 1.33 |
ENST00000552550.1
|
PXN
|
paxillin |
| chr11_-_128457446 | 1.32 |
ENST00000392668.4
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| chr3_-_71179988 | 1.32 |
ENST00000491238.1
|
FOXP1
|
forkhead box P1 |
| chr1_+_209929377 | 1.31 |
ENST00000400959.3
ENST00000367025.3 |
TRAF3IP3
|
TRAF3 interacting protein 3 |
| chr6_+_37787704 | 1.30 |
ENST00000474522.1
|
ZFAND3
|
zinc finger, AN1-type domain 3 |
| chr1_-_144364246 | 1.30 |
ENST00000540273.1
|
PPIAL4B
|
peptidylprolyl isomerase A (cyclophilin A)-like 4B |
| chr15_-_78358465 | 1.29 |
ENST00000435468.1
|
TBC1D2B
|
TBC1 domain family, member 2B |
| chr1_-_94147385 | 1.29 |
ENST00000260502.6
|
BCAR3
|
breast cancer anti-estrogen resistance 3 |
| chr14_-_23564320 | 1.29 |
ENST00000605057.1
|
ACIN1
|
apoptotic chromatin condensation inducer 1 |
| chr4_+_2800722 | 1.28 |
ENST00000508385.1
|
SH3BP2
|
SH3-domain binding protein 2 |
| chr2_+_182850551 | 1.26 |
ENST00000452904.1
ENST00000409137.3 ENST00000280295.3 |
PPP1R1C
|
protein phosphatase 1, regulatory (inhibitor) subunit 1C |
| chr12_-_54121212 | 1.26 |
ENST00000548263.1
ENST00000430117.2 ENST00000550804.1 ENST00000549173.1 ENST00000551900.1 ENST00000546619.1 ENST00000548177.1 ENST00000549349.1 |
CALCOCO1
|
calcium binding and coiled-coil domain 1 |
| chr12_+_25205446 | 1.25 |
ENST00000557489.1
ENST00000354454.3 ENST00000536173.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr15_-_64665911 | 1.24 |
ENST00000606793.1
ENST00000561349.1 ENST00000560278.1 |
CTD-2116N17.1
|
Uncharacterized protein |
| chr17_-_56494908 | 1.24 |
ENST00000577716.1
|
RNF43
|
ring finger protein 43 |
| chr12_-_54121261 | 1.23 |
ENST00000549784.1
ENST00000262059.4 |
CALCOCO1
|
calcium binding and coiled-coil domain 1 |
| chr11_+_35198118 | 1.23 |
ENST00000525211.1
ENST00000526000.1 ENST00000279452.6 ENST00000527889.1 |
CD44
|
CD44 molecule (Indian blood group) |
| chr12_-_96793142 | 1.22 |
ENST00000552262.1
ENST00000551816.1 ENST00000552496.1 |
CDK17
|
cyclin-dependent kinase 17 |
| chr1_+_12524965 | 1.21 |
ENST00000471923.1
|
VPS13D
|
vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| chr4_+_89444961 | 1.17 |
ENST00000513325.1
|
HERC3
|
HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| chr1_+_209929494 | 1.17 |
ENST00000367026.3
|
TRAF3IP3
|
TRAF3 interacting protein 3 |
| chr1_+_156308245 | 1.15 |
ENST00000368253.2
ENST00000470342.1 ENST00000368254.1 |
TSACC
|
TSSK6 activating co-chaperone |
| chr2_+_33359646 | 1.15 |
ENST00000390003.4
ENST00000418533.2 |
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr12_-_49245916 | 1.14 |
ENST00000552512.1
ENST00000551468.1 |
DDX23
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 |
| chr8_+_27168988 | 1.14 |
ENST00000397501.1
ENST00000338238.4 ENST00000544172.1 |
PTK2B
|
protein tyrosine kinase 2 beta |
| chr12_-_10542617 | 1.14 |
ENST00000240618.6
|
KLRK1
|
killer cell lectin-like receptor subfamily K, member 1 |
| chr19_+_10197463 | 1.14 |
ENST00000590378.1
ENST00000397881.3 |
C19orf66
|
chromosome 19 open reading frame 66 |
| chr9_-_34048873 | 1.13 |
ENST00000449054.1
ENST00000379239.4 ENST00000539807.1 ENST00000379238.1 ENST00000418786.2 ENST00000360802.1 ENST00000412543.1 |
UBAP2
|
ubiquitin associated protein 2 |
| chr17_+_7461849 | 1.11 |
ENST00000338784.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr19_-_14048804 | 1.11 |
ENST00000254320.3
ENST00000586075.1 |
PODNL1
|
podocan-like 1 |
| chr3_+_49977523 | 1.11 |
ENST00000422955.1
|
RBM6
|
RNA binding motif protein 6 |
| chr3_+_41240986 | 1.11 |
ENST00000396185.3
|
CTNNB1
|
catenin (cadherin-associated protein), beta 1, 88kDa |
| chr12_-_48276710 | 1.10 |
ENST00000550314.1
|
VDR
|
vitamin D (1,25- dihydroxyvitamin D3) receptor |
| chr20_+_19870167 | 1.09 |
ENST00000440354.2
|
RIN2
|
Ras and Rab interactor 2 |
| chr16_+_2802623 | 1.09 |
ENST00000576924.1
ENST00000575009.1 ENST00000576415.1 ENST00000571378.1 |
SRRM2
|
serine/arginine repetitive matrix 2 |
| chr1_+_151171012 | 1.09 |
ENST00000349792.5
ENST00000409426.1 ENST00000441902.2 ENST00000368890.4 ENST00000424999.1 ENST00000368888.4 |
PIP5K1A
|
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| chr17_-_56494882 | 1.08 |
ENST00000584437.1
|
RNF43
|
ring finger protein 43 |
| chr3_+_49977490 | 1.07 |
ENST00000539992.1
|
RBM6
|
RNA binding motif protein 6 |
| chr3_+_50284321 | 1.06 |
ENST00000451956.1
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| chr17_-_2169425 | 1.04 |
ENST00000570606.1
ENST00000354901.4 |
SMG6
|
SMG6 nonsense mediated mRNA decay factor |
| chr6_-_30043539 | 1.04 |
ENST00000376751.3
ENST00000244360.6 |
RNF39
|
ring finger protein 39 |
| chr6_+_151042224 | 1.04 |
ENST00000358517.2
|
PLEKHG1
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 1 |
| chr5_+_67576062 | 1.03 |
ENST00000523807.1
|
PIK3R1
|
phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| chr1_+_156308403 | 1.02 |
ENST00000481479.1
ENST00000368252.1 ENST00000466306.1 ENST00000368251.1 |
TSACC
|
TSSK6 activating co-chaperone |
| chr8_+_27183033 | 1.02 |
ENST00000420218.2
|
PTK2B
|
protein tyrosine kinase 2 beta |
| chr17_-_56494713 | 1.00 |
ENST00000407977.2
|
RNF43
|
ring finger protein 43 |
| chrX_-_80377162 | 0.99 |
ENST00000430960.1
ENST00000447319.1 |
HMGN5
|
high mobility group nucleosome binding domain 5 |
| chr2_+_234545148 | 0.98 |
ENST00000373445.1
|
UGT1A10
|
UDP glucuronosyltransferase 1 family, polypeptide A10 |
| chr12_-_56753858 | 0.97 |
ENST00000314128.4
ENST00000557235.1 ENST00000418572.2 |
STAT2
|
signal transducer and activator of transcription 2, 113kDa |
| chr12_+_25205568 | 0.95 |
ENST00000548766.1
ENST00000556887.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr19_+_56989609 | 0.94 |
ENST00000601875.1
|
ZNF667-AS1
|
ZNF667 antisense RNA 1 (head to head) |
| chrM_+_8527 | 0.93 |
ENST00000361899.2
|
MT-ATP6
|
mitochondrially encoded ATP synthase 6 |
| chr17_+_7462103 | 0.93 |
ENST00000396545.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr6_+_25279759 | 0.93 |
ENST00000377969.3
|
LRRC16A
|
leucine rich repeat containing 16A |
| chrX_-_80377118 | 0.92 |
ENST00000373250.3
|
HMGN5
|
high mobility group nucleosome binding domain 5 |
| chr10_-_29811456 | 0.92 |
ENST00000535393.1
|
SVIL
|
supervillin |
| chr3_-_56950407 | 0.91 |
ENST00000496106.1
|
ARHGEF3
|
Rho guanine nucleotide exchange factor (GEF) 3 |
| chr12_-_58145889 | 0.89 |
ENST00000547853.1
|
CDK4
|
cyclin-dependent kinase 4 |
| chr8_-_116681221 | 0.89 |
ENST00000395715.3
|
TRPS1
|
trichorhinophalangeal syndrome I |
| chr11_-_66103867 | 0.88 |
ENST00000424433.2
|
RIN1
|
Ras and Rab interactor 1 |
| chr8_-_101718991 | 0.87 |
ENST00000517990.1
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr11_+_114310102 | 0.86 |
ENST00000265881.5
|
REXO2
|
RNA exonuclease 2 |
| chr3_-_4508925 | 0.85 |
ENST00000534863.1
ENST00000383843.5 ENST00000458465.2 ENST00000405420.2 ENST00000272902.5 |
SUMF1
|
sulfatase modifying factor 1 |
| chr2_+_220325441 | 0.84 |
ENST00000396688.1
|
SPEG
|
SPEG complex locus |
| chr8_+_27182862 | 0.84 |
ENST00000521164.1
ENST00000346049.5 |
PTK2B
|
protein tyrosine kinase 2 beta |
| chr1_+_230193521 | 0.84 |
ENST00000543760.1
|
GALNT2
|
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) |
| chr6_-_112081113 | 0.83 |
ENST00000517419.1
|
FYN
|
FYN oncogene related to SRC, FGR, YES |
| chr11_+_114310164 | 0.83 |
ENST00000544196.1
ENST00000539754.1 ENST00000539275.1 |
REXO2
|
RNA exonuclease 2 |
| chr15_-_93632421 | 0.82 |
ENST00000329082.7
|
RGMA
|
repulsive guidance molecule family member a |
| chr5_+_67535647 | 0.82 |
ENST00000520675.1
|
PIK3R1
|
phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| chr1_-_151798546 | 0.81 |
ENST00000356728.6
|
RORC
|
RAR-related orphan receptor C |
| chr4_+_71600063 | 0.80 |
ENST00000513597.1
|
RUFY3
|
RUN and FYVE domain containing 3 |
| chr1_-_179112189 | 0.80 |
ENST00000512653.1
ENST00000344730.3 |
ABL2
|
c-abl oncogene 2, non-receptor tyrosine kinase |
| chr11_+_117049910 | 0.79 |
ENST00000431081.2
ENST00000524842.1 |
SIDT2
|
SID1 transmembrane family, member 2 |
| chr3_+_51575596 | 0.79 |
ENST00000409535.2
|
RAD54L2
|
RAD54-like 2 (S. cerevisiae) |
| chr11_-_118047376 | 0.79 |
ENST00000278947.5
|
SCN2B
|
sodium channel, voltage-gated, type II, beta subunit |
| chr12_-_4754356 | 0.78 |
ENST00000540967.1
|
AKAP3
|
A kinase (PRKA) anchor protein 3 |
| chr12_-_53594227 | 0.78 |
ENST00000550743.2
|
ITGB7
|
integrin, beta 7 |
| chr19_+_7580103 | 0.78 |
ENST00000596712.1
|
ZNF358
|
zinc finger protein 358 |
| chr19_-_14064114 | 0.77 |
ENST00000585607.1
ENST00000538517.2 ENST00000587458.1 ENST00000538371.2 |
PODNL1
|
podocan-like 1 |
| chr12_+_25205155 | 0.76 |
ENST00000550945.1
|
LRMP
|
lymphoid-restricted membrane protein |
| chr8_-_116681123 | 0.75 |
ENST00000519674.1
|
TRPS1
|
trichorhinophalangeal syndrome I |
| chr12_-_4754318 | 0.73 |
ENST00000536414.1
|
AKAP3
|
A kinase (PRKA) anchor protein 3 |
| chr1_-_184006611 | 0.72 |
ENST00000546159.1
|
COLGALT2
|
collagen beta(1-O)galactosyltransferase 2 |
| chr1_+_117544366 | 0.72 |
ENST00000256652.4
ENST00000369470.1 |
CD101
|
CD101 molecule |
| chr1_-_115300579 | 0.72 |
ENST00000358528.4
ENST00000525132.1 |
CSDE1
|
cold shock domain containing E1, RNA-binding |
| chr19_-_42636543 | 0.72 |
ENST00000528894.4
ENST00000560804.2 ENST00000560558.1 ENST00000560398.1 ENST00000526816.2 |
POU2F2
|
POU class 2 homeobox 2 |
| chr1_-_150978953 | 0.72 |
ENST00000493834.2
|
FAM63A
|
family with sequence similarity 63, member A |
| chr10_+_115511213 | 0.72 |
ENST00000361048.1
|
PLEKHS1
|
pleckstrin homology domain containing, family S member 1 |
| chr6_+_25279651 | 0.72 |
ENST00000329474.6
|
LRRC16A
|
leucine rich repeat containing 16A |
| chrM_+_8366 | 0.71 |
ENST00000361851.1
|
MT-ATP8
|
mitochondrially encoded ATP synthase 8 |
| chr8_-_72274355 | 0.71 |
ENST00000388741.2
|
EYA1
|
eyes absent homolog 1 (Drosophila) |
| chr8_-_72274467 | 0.71 |
ENST00000340726.3
|
EYA1
|
eyes absent homolog 1 (Drosophila) |
| chr11_-_61124776 | 0.71 |
ENST00000542361.1
|
CYB561A3
|
cytochrome b561 family, member A3 |
| chr1_-_150979333 | 0.70 |
ENST00000312210.5
|
FAM63A
|
family with sequence similarity 63, member A |
| chr9_+_125795788 | 0.70 |
ENST00000373643.5
|
RABGAP1
|
RAB GTPase activating protein 1 |
| chr17_-_73178599 | 0.70 |
ENST00000578238.1
|
SUMO2
|
small ubiquitin-like modifier 2 |
| chrX_+_22050546 | 0.68 |
ENST00000379374.4
|
PHEX
|
phosphate regulating endopeptidase homolog, X-linked |
| chr1_-_115300592 | 0.67 |
ENST00000261443.5
ENST00000534699.1 ENST00000339438.6 ENST00000529046.1 ENST00000525970.1 ENST00000369530.1 ENST00000530886.1 |
CSDE1
|
cold shock domain containing E1, RNA-binding |
| chr15_+_68582544 | 0.67 |
ENST00000566008.1
|
FEM1B
|
fem-1 homolog b (C. elegans) |
| chr2_+_33359473 | 0.67 |
ENST00000432635.1
|
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr11_-_66103932 | 0.67 |
ENST00000311320.4
|
RIN1
|
Ras and Rab interactor 1 |
| chr1_+_24120143 | 0.67 |
ENST00000374501.1
|
LYPLA2
|
lysophospholipase II |
| chr5_-_127674883 | 0.67 |
ENST00000507835.1
|
FBN2
|
fibrillin 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of RUNX3_BCL11A
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.6 | 18.5 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
| 3.7 | 14.6 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 1.4 | 18.5 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 1.4 | 5.5 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 1.3 | 4.0 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 1.2 | 3.7 | GO:0002025 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) |
| 1.0 | 3.1 | GO:0097195 | pilomotor reflex(GO:0097195) |
| 1.0 | 5.9 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.7 | 2.8 | GO:0052362 | multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419) |
| 0.7 | 3.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.6 | 10.9 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 0.6 | 4.2 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.6 | 5.4 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.5 | 5.4 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.5 | 2.1 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 0.5 | 2.9 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.5 | 1.9 | GO:1903045 | neural crest cell migration involved in sympathetic nervous system development(GO:1903045) |
| 0.5 | 3.3 | GO:2000490 | negative regulation of hepatic stellate cell activation(GO:2000490) |
| 0.5 | 7.3 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.4 | 3.0 | GO:0010752 | regulation of cGMP-mediated signaling(GO:0010752) |
| 0.4 | 2.5 | GO:1990523 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523) |
| 0.4 | 6.6 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.4 | 1.1 | GO:2000502 | negative regulation of natural killer cell chemotaxis(GO:2000502) |
| 0.4 | 2.6 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.4 | 3.0 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.4 | 7.7 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.4 | 1.4 | GO:0000354 | cis assembly of pre-catalytic spliceosome(GO:0000354) |
| 0.4 | 3.9 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.3 | 2.1 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.3 | 3.4 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.3 | 1.1 | GO:0010979 | regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
| 0.3 | 0.8 | GO:0002874 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) |
| 0.3 | 2.2 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.3 | 1.0 | GO:2001303 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303) |
| 0.3 | 0.3 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 0.2 | 2.0 | GO:0003383 | apical constriction(GO:0003383) |
| 0.2 | 1.7 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.2 | 0.6 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.2 | 2.6 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.2 | 0.6 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.2 | 1.4 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.2 | 0.4 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 0.2 | 1.9 | GO:2000489 | regulation of hepatic stellate cell activation(GO:2000489) |
| 0.2 | 0.5 | GO:1902771 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.2 | 4.5 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.2 | 0.7 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.2 | 0.8 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.2 | 2.8 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.2 | 2.8 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.2 | 1.3 | GO:0030578 | PML body organization(GO:0030578) |
| 0.2 | 3.6 | GO:0033160 | positive regulation of protein import into nucleus, translocation(GO:0033160) |
| 0.2 | 2.7 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.2 | 0.8 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.2 | 5.7 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.1 | 1.0 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.1 | 7.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 0.4 | GO:0070676 | intralumenal vesicle formation(GO:0070676) |
| 0.1 | 2.3 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.1 | 0.7 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.1 | 0.4 | GO:0033488 | cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488) |
| 0.1 | 3.1 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.1 | 1.6 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 0.5 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.1 | 1.3 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.1 | 1.7 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.1 | 0.6 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.1 | 0.4 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 0.1 | 0.4 | GO:0045362 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
| 0.1 | 0.4 | GO:2000523 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.1 | 0.8 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.1 | 0.7 | GO:1901911 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.1 | 0.4 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 0.1 | 0.4 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.1 | 1.4 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.1 | 1.5 | GO:0061458 | reproductive system development(GO:0061458) |
| 0.1 | 3.0 | GO:0002335 | mature B cell differentiation(GO:0002335) |
| 0.1 | 0.8 | GO:0097398 | response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398) |
| 0.1 | 1.4 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.1 | 0.5 | GO:0046086 | adenosine biosynthetic process(GO:0046086) |
| 0.1 | 2.6 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.1 | 1.4 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 0.6 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.1 | 0.9 | GO:1904636 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 0.1 | 2.3 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.1 | 1.7 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.1 | 1.3 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.1 | 0.6 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.1 | 1.5 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 1.9 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.1 | 1.8 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.1 | 3.1 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 0.4 | GO:0060283 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 0.4 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.1 | 0.3 | GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 0.1 | 0.2 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.1 | 1.9 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.1 | 1.8 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 1.3 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.1 | 0.7 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.1 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.1 | 0.7 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.1 | 1.3 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.1 | 0.4 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) |
| 0.1 | 0.8 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.1 | 0.4 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.1 | 1.1 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.1 | 0.7 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 0.4 | GO:0043129 | surfactant homeostasis(GO:0043129) |
| 0.1 | 0.2 | GO:0050894 | determination of affect(GO:0050894) |
| 0.1 | 0.2 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 0.1 | 0.5 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 1.7 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.0 | 1.0 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.3 | GO:0072156 | distal tubule morphogenesis(GO:0072156) |
| 0.0 | 1.0 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
| 0.0 | 0.6 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.0 | 2.3 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 2.3 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.0 | 2.7 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 2.6 | GO:0001755 | neural crest cell migration(GO:0001755) |
| 0.0 | 0.6 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.0 | 0.3 | GO:0072092 | ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093) |
| 0.0 | 0.8 | GO:0043981 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 0.3 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.0 | 0.2 | GO:0048010 | vascular endothelial growth factor receptor signaling pathway(GO:0048010) |
| 0.0 | 1.3 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.3 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.0 | 2.4 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.0 | 0.7 | GO:2000059 | negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059) |
| 0.0 | 0.5 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.0 | 0.5 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.0 | 1.5 | GO:0042407 | cristae formation(GO:0042407) |
| 0.0 | 0.2 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.0 | 0.3 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.0 | 0.8 | GO:0060850 | regulation of transcription involved in cell fate commitment(GO:0060850) |
| 0.0 | 0.3 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.0 | 0.2 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.0 | 0.5 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.0 | 0.5 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 2.2 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.1 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
| 0.0 | 0.5 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.0 | 1.0 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.0 | 1.6 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 0.6 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 0.1 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.0 | 0.6 | GO:0006939 | smooth muscle contraction(GO:0006939) |
| 0.0 | 0.3 | GO:0001553 | luteinization(GO:0001553) |
| 0.0 | 0.8 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.6 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.0 | 1.3 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 0.2 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.5 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 0.6 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 1.1 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 1.6 | GO:0051972 | regulation of telomerase activity(GO:0051972) |
| 0.0 | 0.1 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.0 | 3.4 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 1.9 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.8 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.1 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) |
| 0.0 | 0.2 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.0 | 0.4 | GO:0098743 | cell aggregation(GO:0098743) |
| 0.0 | 0.1 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
| 0.0 | 2.8 | GO:0007338 | single fertilization(GO:0007338) |
| 0.0 | 0.4 | GO:0042574 | retinal metabolic process(GO:0042574) |
| 0.0 | 0.3 | GO:0002097 | tRNA wobble base modification(GO:0002097) |
| 0.0 | 0.3 | GO:0034205 | beta-amyloid formation(GO:0034205) |
| 0.0 | 0.1 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.0 | 0.2 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 0.7 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.0 | 1.3 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.5 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
| 0.0 | 0.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.3 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.0 | 0.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.2 | GO:0006071 | glycerol metabolic process(GO:0006071) |
| 0.0 | 0.7 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.2 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.3 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.1 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
| 0.0 | 0.6 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.1 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 7.3 | GO:0034676 | integrin alpha6-beta4 complex(GO:0034676) |
| 0.8 | 2.3 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.6 | 2.8 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.5 | 3.1 | GO:0034678 | smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678) |
| 0.4 | 3.0 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.3 | 2.4 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.2 | 2.6 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.2 | 3.1 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.2 | 0.6 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.2 | 1.0 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 0.2 | 5.8 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.2 | 0.8 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.1 | 3.9 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.6 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.1 | 2.0 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.1 | 2.7 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 3.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 1.3 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.1 | 9.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 4.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 1.6 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 0.9 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.1 | 7.9 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 1.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 11.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 2.2 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 0.6 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 1.6 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.1 | 8.9 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.1 | 0.5 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 1.1 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 0.2 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.9 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.0 | 0.3 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.0 | 0.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 1.4 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 0.4 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 18.1 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 0.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.4 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.0 | 3.4 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.6 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.1 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.0 | 0.8 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 0.4 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.0 | 0.6 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 1.2 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 0.4 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.2 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.0 | 3.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 2.8 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 0.6 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.6 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.2 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 1.3 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.5 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.0 | 0.3 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 1.4 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.4 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 2.5 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 0.2 | GO:0030990 | intraciliary transport particle(GO:0030990) |
| 0.0 | 0.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 1.9 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 0.1 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.0 | 0.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 18.3 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 1.5 | 4.5 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 1.2 | 3.7 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
| 0.9 | 14.6 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.9 | 3.6 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 0.8 | 3.3 | GO:0047888 | fatty acid peroxidase activity(GO:0047888) |
| 0.6 | 5.5 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.5 | 3.2 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.5 | 7.3 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.5 | 3.0 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.4 | 2.6 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.4 | 1.8 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.4 | 1.1 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 0.4 | 4.2 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.3 | 1.6 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.3 | 20.9 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.3 | 1.1 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 0.3 | 8.0 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.3 | 1.5 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.3 | 1.0 | GO:0047977 | hepoxilin-epoxide hydrolase activity(GO:0047977) |
| 0.2 | 1.3 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.2 | 7.1 | GO:0032041 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.2 | 2.3 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.2 | 0.6 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.2 | 2.0 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.2 | 0.7 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 0.2 | 2.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.1 | 1.2 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 1.5 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.1 | 1.8 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.1 | 0.4 | GO:0008398 | sterol 14-demethylase activity(GO:0008398) |
| 0.1 | 3.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.4 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 0.1 | 3.1 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 0.7 | GO:0034432 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.1 | 0.4 | GO:0004082 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 0.1 | 0.5 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 0.1 | 4.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 1.9 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.1 | 1.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.8 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.1 | 0.6 | GO:0070728 | leucine binding(GO:0070728) |
| 0.1 | 1.3 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 4.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 0.4 | GO:0005502 | 11-cis retinal binding(GO:0005502) all-trans retinal binding(GO:0005503) |
| 0.1 | 0.7 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 0.4 | GO:0005011 | macrophage colony-stimulating factor receptor activity(GO:0005011) |
| 0.1 | 3.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 0.7 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.1 | 0.8 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 0.6 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 3.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 4.0 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 0.4 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.1 | 0.8 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.1 | 0.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 0.7 | GO:0031386 | protein tag(GO:0031386) |
| 0.1 | 0.4 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 0.2 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
| 0.1 | 0.2 | GO:0004961 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 0.1 | 0.4 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.0 | 0.8 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.0 | 0.6 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.8 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.0 | 0.7 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 1.4 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 1.6 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.5 | GO:0009374 | biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374) |
| 0.0 | 2.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.3 | GO:0045569 | TRAIL binding(GO:0045569) |
| 0.0 | 1.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 5.4 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 1.1 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 1.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 1.9 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.2 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.0 | 2.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 1.1 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.0 | 3.2 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 3.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 1.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 3.1 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 2.0 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.7 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 1.6 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.0 | 0.3 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.0 | 1.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 1.0 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 2.1 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 1.1 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.0 | 0.5 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.0 | 0.8 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.7 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.2 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.0 | 0.5 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.0 | 0.1 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.0 | 1.1 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 1.0 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 0.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.8 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.3 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 0.5 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 0.1 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
| 0.0 | 0.5 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 2.6 | GO:0070851 | growth factor receptor binding(GO:0070851) |
| 0.0 | 0.6 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 4.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.5 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 0.6 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) ankyrin binding(GO:0030506) |
| 0.0 | 0.4 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.1 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.0 | 0.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.2 | GO:0031701 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.0 | 0.5 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.0 | 0.3 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.0 | 1.1 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 0.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.1 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.0 | 1.2 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 1.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.7 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 0.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.0 | 0.6 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 18.7 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.2 | 22.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 2.7 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 8.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 4.9 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 2.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.1 | 3.5 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 2.1 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 2.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 7.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 2.5 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.1 | 1.0 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.1 | 4.0 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 1.1 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 2.3 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 3.1 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 3.8 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 0.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 4.5 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 2.2 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.0 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 1.8 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 5.3 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.8 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 2.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 1.8 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 1.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 3.5 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 1.0 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 1.3 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 1.4 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 0.1 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 1.1 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.2 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 2.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 1.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.3 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.3 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.0 | 0.3 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.3 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 1.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 19.3 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.2 | 8.5 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.2 | 6.0 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 4.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 4.0 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.1 | 3.7 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 3.7 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 2.7 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 2.1 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.1 | 4.6 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 4.2 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 2.6 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 2.4 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 7.1 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 0.5 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 1.6 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 1.1 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 1.0 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 0.8 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 1.1 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.0 | 2.2 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 2.9 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 0.5 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 2.0 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 2.0 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.9 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.5 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 2.0 | REACTOME EXTRACELLULAR MATRIX ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.0 | 0.6 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.2 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 4.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.3 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.3 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.0 | 3.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.9 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.3 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 1.2 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.8 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 2.3 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.0 | 0.2 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 1.8 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 0.0 | 1.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.4 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 1.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.9 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |