Project
SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for RXRA_NR2F6_NR2C2
Z-value: 0.86
Motif logo
Transcription factors associated with RXRA_NR2F6_NR2C2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000186350.8 | retinoid X receptor alpha | |
| ENSG00000160113.5 | nuclear receptor subfamily 2 group F member 6 | |
| ENSG00000177463.11 | nuclear receptor subfamily 2 group C member 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NR2C2 | hg19_v2_chr3_+_14989186_14989236 | -0.84 | 3.0e-06 | Click! |
| RXRA | hg19_v2_chr9_+_137298396_137298431 | -0.76 | 8.8e-05 | Click! |
| NR2F6 | hg19_v2_chr19_-_17356697_17356762 | 0.37 | 1.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_48867291 Show fit | 2.24 |
ENST00000435956.3
|
transmembrane protein 143 |
|
| chr19_-_36304201 Show fit | 2.17 |
ENST00000301175.3
|
proline dehydrogenase (oxidase) 2 |
|
| chr19_-_48867171 Show fit | 2.12 |
ENST00000377431.2
ENST00000436660.2 ENST00000541566.1 |
transmembrane protein 143 |
|
| chr16_-_4401258 Show fit | 1.61 |
ENST00000577031.1
|
presequence translocase-associated motor 16 homolog (S. cerevisiae) |
|
| chr19_+_50919056 Show fit | 1.60 |
ENST00000599632.1
|
CTD-2545M3.6 |
|
| chr16_-_4401284 Show fit | 1.49 |
ENST00000318059.3
|
presequence translocase-associated motor 16 homolog (S. cerevisiae) |
|
| chr19_+_10197463 Show fit | 1.42 |
ENST00000590378.1
ENST00000397881.3 |
chromosome 19 open reading frame 66 |
|
| chr19_+_49055332 Show fit | 1.42 |
ENST00000201586.2
|
sulfotransferase family, cytosolic, 2B, member 1 |
|
| chr3_-_119396193 Show fit | 1.35 |
ENST00000484810.1
ENST00000497116.1 ENST00000261070.2 |
COX17 cytochrome c oxidase copper chaperone |
|
| chr5_-_176981417 Show fit | 1.28 |
ENST00000514747.1
ENST00000443375.2 ENST00000329540.5 |
family with sequence similarity 193, member B |
Network of associatons between targets according to the STRING database.
First level regulatory network of RXRA_NR2F6_NR2C2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.5 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.1 | 3.1 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 2.5 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
| 0.2 | 2.4 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.7 | 2.2 | GO:0070902 | mitochondrial tRNA pseudouridine synthesis(GO:0070902) |
| 0.3 | 2.2 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.0 | 1.9 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.6 | 1.8 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.4 | 1.8 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 0.1 | 1.8 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.5 | 2.6 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.0 | 2.5 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 2.4 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 2.4 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 1.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 1.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.8 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 1.6 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 1.6 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.5 | GO:0001848 | complement binding(GO:0001848) |
| 0.7 | 2.2 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 0.5 | 2.2 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.0 | 2.2 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 2.0 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 1.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 1.7 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 1.5 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 1.5 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.2 | 1.4 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 3.0 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 2.6 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.2 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 0.9 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.0 | 0.8 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.7 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.7 | ST GA13 PATHWAY | G alpha 13 Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.1 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.0 | 2.9 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 2.6 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 2.5 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 2.2 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 2.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 2.0 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 1.9 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 1.5 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 1.5 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |